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Author |
Machnik, M.; Hegger, I.; Kietzmann, M.; Thevis, M.; Guddat, S.; Schanzer, W. |
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Title |
Pharmacokinetics of altrenogest in horses |
Type |
Journal Article |
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Year |
2007 |
Publication  |
Journal of Veterinary Pharmacology and Therapeutics |
Abbreviated Journal |
J Vet Pharmacol Ther |
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Volume |
30 |
Issue |
1 |
Pages |
86-90 |
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Keywords |
Administration, Oral; Animals; Chromatography, Liquid/veterinary; Doping in Sports/prevention & control; Horses/*metabolism; Male; Mass Spectrometry/veterinary; Progesterone Congeners/administration & dosage/blood/*pharmacokinetics/urine; Reproducibility of Results; Substance Abuse Detection/veterinary; Trenbolone/administration & dosage/*analogs & derivatives/blood/pharmacokinetics/urine |
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Abstract |
The Federation Equestre Internationale has permitted the use of altrenogest in mares for the control of oestrus. However, altrenogest is also suspicious to misuse in competition horses for its potential anabolic effects and suppression of typical male behaviour, and thus is a controlled drug. To investigate the pharmacokinetics of altrenogest in horses we conducted an elimination study. Five oral doses of 44 mug/kg altrenogest were administered to 10 horses at a dose interval of 24 h. Following administration blood and urine samples were collected at appropriate intervals. Altrenogest concentrations were measured by liquid chromatography-tandem mass spectrometry. The plasma levels of altrenogest reached maximal concentrations of 23-75 ng/mL. Baseline values were achieved within 3 days after the final administration. Urine peak concentrations of total altrenogest ranged from 823 to 3895 ng/mL. Twelve days after the final administration concentrations were below the limit of detection (ca 2 ng/mL). |
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Institute of Biochemistry, German Sport University, Cologne, Germany. m.machnik@biochem.dshs-koeln.de |
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0140-7783 |
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PMID:17217407 |
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Serial |
1841 |
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Author |
Zehnder, A.M.; Ramer, J.C.; Proudfoot, J.S. |
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Title |
The use of altrenogest to control aggression in a male Grant's Zebra (Equus burchelli boehmi) |
Type |
Journal Article |
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Year |
2006 |
Publication |
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians |
Abbreviated Journal |
J Zoo Wildl Med |
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Volume |
37 |
Issue |
1 |
Pages |
61-63 |
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Keywords |
Aggression/*drug effects; Animals; Animals, Zoo; Behavior, Animal/*drug effects; Dose-Response Relationship, Drug; Equidae/*physiology; Female; Horses; Male; Treatment Outcome; Trenbolone/*analogs & derivatives/therapeutic use |
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A male Grant's Zebra (Equus burchelli boehmi) housed with two mares at the Indianapolis Zoo had a 9-yr history of intermittent aggressive behavior toward mares and other animals. Periods of separation allowed the mares time to heal after sustaining superficial bite wounds. On 26 March 2003, the male (890293) was started on altrenogest at a dosage of 19.8 mg orally once daily to allow reintroduction. The dosage was doubled (40 mg once a day) because of a perceived lack of response. Reintroduction to the mares occurred on 17 May 2003 with no signs of aggression noted. Treatment was reduced to 19.8 mg orally once a day and then discontinued. Altrenogest was restarted at 39.5 mg orally once a day because of the planned introduction of a new mare. There have been no major aggressive displays at this dosage of altrenogest and the dosage has recently been reduced following successful introduction of a new mare. |
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University of Florida, 2015 SW 16th Street, Gainesville, Florida 32610, USA |
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1042-7260 |
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PMID:17312816 |
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1772 |
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Author |
Robert, N.; Walzer, C.; Ruegg, S.R.; Kaczensky, P.; Ganbaatar, O.; Stauffer, C. |
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Title |
Pathologic findings in reintroduced Przewalski's horses (Equus caballus przewalskii) in southwestern Mongolia |
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Journal Article |
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Year |
2005 |
Publication |
Journal of zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians |
Abbreviated Journal |
J Zoo Wildl Med |
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Volume |
36 |
Issue |
2 |
Pages |
273-285 |
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Keywords |
Animals; Babesiosis/epidemiology/pathology/*veterinary; Cause of Death; Conservation of Natural Resources; Disease Susceptibility/veterinary; Environment; Female; Food Chain; Horse Diseases/*epidemiology/pathology; Horses; Male; Mongolia/epidemiology; Streptococcal Infections/epidemiology/pathology/*veterinary; *Streptococcus equi; Theileriasis/*epidemiology/pathology; Weather |
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The Przewalski's horse (Equus caballus przewalskii) was extinct in the wild by the mid 1960s. The species has survived because of captive breeding only. The Takhin Tal reintroduction project is run by the International Takhi Group; it is one of two projects reintroducing horses to the wild in Mongolia. In 1997 the first harem group was released. The first foals were successfully raised in the wild in 1999. Currently, 63 Przewalski's horses live in Takhin Tal. Little information exists on causes of mortality before the implementation of a disease-monitoring program in 1998. Since 1999, all dead horses recovered (n = 28) have been examined and samples collected and submitted for further investigation. Equine piroplasmosis, a tick-transmitted disease caused by Babesia caballi or Theileria equi, is endemic in Takhin Tal and was identified as the cause of death of four stallions and one stillborn foal. In December 2000, wolf predation was implicated in the loss of several Przewalski's horses. However, thorough clinical, pathologic, and bacteriologic investigations performed on dead and surviving horses of this group revealed lesions compatible with strangles. The extreme Mongolian winter of 2000-2001 is thought to have most probably weakened the horses, making them more susceptible to opportunistic infection and subsequent wolf predation. Other occasional causes of death since 1999 were trauma, exhaustion, wasting, urolithiasis, pneumonia, abortion, and stillbirth. The pathologic examination of the Przewalski's horses did not result in a definitive diagnosis in each case. Several disease factors were found to be important in the initial phase of the reintroduction, which could potentially jeopardize the establishment of a self-sustaining population. |
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Center for Fish and Wildlife Health, Institute of Animal Pathology, University of Berne, Langgass-Strasse 122, CH-3001 Berne, Switzerland |
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1042-7260 |
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PMID:17323569 |
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2023 |
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Author |
Leadbeater, E. |
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Title |
What evolves in the evolution of social learning? |
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Journal Article |
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Year |
2015 |
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Journal of Zoology |
Abbreviated Journal |
J Zool |
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295 |
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1 |
Pages |
4-11 |
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Keywords |
social learning; associative learning; social information use |
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Social learning is fundamental to social life across the animal kingdom, but we still know little about how natural selection has shaped social learning abilities on a proximate level. Sometimes, complex social learning phenomena can be entirely explained by Pavlovian processes that have little to do with the evolution of sociality. This implies that the ability to learn socially could be an exaptation, not an adaptation, to social life but not that social learning abilities have been left untouched by natural selection. I discuss new empirical evidence for associative learning in social information use, explain how natural selection might facilitate the associative learning process and discuss why such studies are changing the way that we think about social learning. |
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1469-7998 |
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Equine Behaviour @ team @ |
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6015 |
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Author |
Linklater, W.L.; Cameron, E.Z.; Stafford, K.J.; Veltman, C.J. |
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Title |
Social and spatial structure and range use by Kaimanawa wild horses (Equus caballus: Equidae) |
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Journal Article |
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Year |
2000 |
Publication |
New Zealand Journal of Ecology |
Abbreviated Journal |
New Zealand J. Ecol. |
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24 |
Issue |
2 |
Pages |
139-152 |
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Keywords |
Bachelor male; Band; Density; Habitat use; Home range; Management proposals; Micro-climate; Vegetation monitoring; habitat use; home range; mammal; social structure; spatial distribution; New Zealand; Equus caballus |
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We measured horse density, social structure, habitat use, home ranges and altitudinal micro-climates in the south-western Kaimanawa ranges east of Waiouru, New Zealand. Horse density in the Auahitotara ecological sector averaged 3.6 horses.km-2 and ranged from 0.9 to 5.2 horses.km-2 within different zones. The population's social structure was like that of other feral horse populations with an even adult sex ratio, year round breeding groups (bands) with stable adult membership consisting of 1 to 11 mares, 1 to 4 stallions, and their predispersal offspring, and bachelor groups with unstable membership. Bands and bachelor males were loyal to undefended home ranges with central core use areas. Band home range sizes varied positively with adult band size. Home ranges overlapped entirely with other home ranges. Horses were more likely to occupy north facing aspects, short tussock vegetation and flush zones and avoid high altitudes, southern aspects, steeper slopes, bare ground and forest remnants. Horses were more likely to be on north facing aspects, steeper slopes, in exotic and red tussock grasslands and flush zones during winter and at lower altitudes and on gentler slopes in spring and summer. Seasonal shifts by bands to river basin and stream valley floors in spring and higher altitudes in autumn and winter are attributed to the beginning of foaling and mating in spring and formation of frost inversion layers in winter. Given horse habitat selectivity and the presence of other ungulate herbivores, results from present exclosures are likely to exaggerate the size of horse impacts on range vegetation. Proposals to manage the population by relocation and confinement are likely to modify current social structure and range use behaviour and may lead to the need for more intensive management in the longer term. |
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Ecology Group, Institute of Natural Resources, Massey University, Private Bag 11-222, Palmerston North, New Zealand |
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01106465 (Issn) |
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Cited By (since 1996): 12; Export Date: 21 April 2007; Source: Scopus; Language of Original Document: English; Correspondence Address: Linklater, W.L.; Ecology Group; Institute of Natural Resources; Massey University; Private Bag 11-222 Palmerston North, New Zealand; email: wlinklater@hotmail.com |
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refbase @ user @ |
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793 |
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Author |
Valone, T.J. |
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Title |
Group foraging, public information, and patch estimation |
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Journal Article |
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Year |
1989 |
Publication |
Oikos |
Abbreviated Journal |
Oikos |
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56 |
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3 |
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357-363 |
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Techniques; Mathematical techniques; Nutrition; Feeding behaviour; Behaviour; Social behaviour^, Comprehensive Zoology; Mathematical model; Resource patch estimation by group members; use of public information; Foraging; Group behaviour |
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Public information is information about the quality of a patch that can be obtained by observing the foraging success of other individuals in that patch. I examine the influence of the use of public information on patch departure and foraging efficiency of group members. When groups depart a patch with the first individual to leave, the use of public information can prevent the underutilization of resource patches. |
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Equine Behaviour @ team @ |
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4274 |
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Author |
Visalberghi E; Trinca L |
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Title |
Tool use in capuchin monkeys: distinguishing between performing and understanding |
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Journal Article |
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Year |
1989 |
Publication |
Primates |
Abbreviated Journal |
Primates |
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30 |
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511 |
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Tool use – Cebus apella – Mental representation |
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A horizontal plexiglas tube containing a food-reward was presented to four naive tufted capuchins and suitable sticks were provided to push the reward out. Three monkeys out of four spontaneously used the tools and showed very different styles of solving the task. In more complex conditions, in which the sticks needed to be combined or actively modified in order to become effective, the monkeys were always successful; however, their performance was loaded with errors which did not disappear throughout the trials. Evidence of a difference between success in solving the problem and its understanding was found. This suggests that although capuchins can discover new means through active experimentation, they do not mentally represent the characteristics necessary for a tool to be effective, nor do they modify the tool appropriately beforehand. At this level, a major difference with chimpanzees emerges. |
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Equine Behaviour @ team @ |
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3047 |
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Ziegler, W.H. |
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Title |
[Endocrinological studies in arterial hypertension. Search for phaeochromocytoma] |
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Journal Article |
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Year |
1976 |
Publication |
Schweizerische Medizinische Wochenschrift |
Abbreviated Journal |
Schweiz Med Wochenschr |
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106 |
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34 |
Pages |
1148-1150 |
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Angiography; Blood Volume; Catecholamines/urine; Glucagon/diagnostic use; Histamine/diagnostic use; Humans; Hydrogen-Ion Concentration; Hypertension/*etiology; Methods; Pheochromocytoma/*complications/diagnosis; Tyramine/diagnostic use |
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Elevated urinary catecholamines and their metabolites are the only findings which confirm the presence of pheochromocytoma. This examination is of particular interest if carried out in urine produced after spontaneous hypertensive episodes. Pharmacologic tests when carried out under standard conditions have proven to be a reliable aid in cases of suspected pheochromocytoma. Roentgenographic studies, determination of local plasma catecholamine concentrations and blood volume control should be undertaken in these patients before surgical procedure. |
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German |
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Endokrinologische Untersuchungen bei arterieller Hypertonie. Suche nach Phaochromozytom |
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0036-7672 |
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PMID:12561 |
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Equine Behaviour @ team @ |
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4047 |
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Author |
Cohen, J. |
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Animal behavior. The world through a chimp's eyes |
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2007 |
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Science (New York, N.Y.) |
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Science |
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316 |
Issue |
5821 |
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44-45 |
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Animal Communication; Animals; *Behavior, Animal; Cognition; Cooperative Behavior; Culture; Memory; Pan troglodytes/*psychology; Social Behavior; Tool Use Behavior |
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1095-9203 |
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PMID:17412932 |
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Equine Behaviour @ team @ |
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2832 |
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Author |
Sabattini, M.S.; Monath, T.P.; Mitchell, C.J.; Daffner, J.F.; Bowen, G.S.; Pauli, R.; Contigiani, M.S. |
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Arbovirus investigations in Argentina, 1977-1980. I. Historical aspects and description of study sites |
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Journal Article |
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1985 |
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The American Journal of Tropical Medicine and Hygiene |
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Am J Trop Med Hyg |
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34 |
Issue |
5 |
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937-944 |
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Animals; Arbovirus Infections/*epidemiology/microbiology; Arboviruses; Argentina; Birds; Cattle; Child; Climate; Ecology; Encephalitis Virus, St. Louis; Encephalitis Virus, Venezuelan Equine; Encephalitis Virus, Western Equine; Encephalitis, St. Louis/epidemiology/microbiology; Encephalomyelitis, Equine/epidemiology/microbiology/veterinary; Encephalomyelitis, Venezuelan Equine/epidemiology/microbiology/veterinary; Geography; Horse Diseases/epidemiology/microbiology; Horses/microbiology; Humans |
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This is the introductory paper to a series on the ecology of arboviruses in Argentina. Epizootics of equine encephalitis have occurred since at least 1908, principally in the Pampa and Espinal biogeographic zones, with significant economic losses; human cases of encephalitis have been rare or absent. Both western equine and eastern equine encephalitis viruses have been isolated from horses during these epizootics, but the mosquitoes responsible for transmission have not been identified. A number of isolations of Venezuelan equine encephalitis (VEE) virus were reported between 1936 and 1958 in Argentina, but the validity of these findings has been seriously questioned. Nevertheless, serological evidence exists for human infections with a member of the VEE virus complex. Serological surveys conducted in the 1960s indicate a high prevalence of infection of humans and domestic animals with St. Louis encephalitis (SLE), and 2 SLE virus strains have been isolated from rodents. Human disease, however, has rarely been associated with SLE infection. Only 7 isolations of other arboviruses have been described (3 of Maguari, 1 of Aura, 2 of Una, and 1 of an untyped Bunyamwera group virus). In 1977, we began longitudinal field studies in Santa Fe Province, the epicenter of previous equine epizootics, and in 1980 we extended these studies to Chaco and Corrientes provinces. The study sites are described in this paper. |
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0002-9637 |
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PMID:4037184 |
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Equine Behaviour @ team @ |
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2685 |
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