| |
Records |
Links |
|
Author |
Bannasch, D.; Rinaldo, C.; Millon, L.; Latson, K.; Spangler, T.; Hubberty, S.; Galuppo, L.; Lowenstine, L. |
|
| |
Title |
SRY negative 64,XX intersex phenotype in an American saddlebred horse |
Type |
Journal Article |
| |
Year |
2007 |
Publication |
Veterinary Journal (London, England : 1997) |
Abbreviated Journal |
Vet J |
|
| |
Volume |
173 |
Issue |
2 |
Pages |
437-439 |
|
| |
Keywords |
Animals; Female; Genitalia/abnormalities; Hermaphroditism/*veterinary; Horse Diseases/*diagnosis/genetics; Horses/*genetics/*physiology; Karyotyping; Phenotype; Sex Differentiation; Sex Differentiation Disorders/diagnosis/veterinary; Sex-Determining Region Y Protein/genetics/*metabolism |
|
| |
Abstract |
A female American saddlebred horse was presented for surgical correction of a possible pseudohermaphrodite condition. The horse had abnormal external genitalia and exhibited stallion-like behaviour. No evidence of uterine or ovarian tissue was identified on laparoscopic examination, but hypoplastic testicular-like tissue was removed, although this was found to contain no spermatogonia upon histopathological examination. A karyotype was performed and showed the normal chromosomal complement for a female horse (64,XX). Polymerase chain reaction to detect the SRY gene was negative in peripheral blood as well as the testicular-like tissue. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse. |
|
| |
Address |
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. dlbannasch@ucdavis.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1090-0233 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:16386440 |
Approved |
no |
|
| |
Call Number  |
|
Serial |
1882 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Piccione, G.; Caola, G.; Refinetti, R. |
|
| |
Title |
Temporal relationships of 21 physiological variables in horse and sheep |
Type |
Journal Article |
| |
Year |
2005 |
Publication |
Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology |
Abbreviated Journal |
Comp Biochem Physiol A Mol Integr Physiol |
|
| |
Volume |
142 |
Issue |
4 |
Pages |
389-396 |
|
| |
Keywords |
Animals; Behavior, Animal/physiology; Blood Glucose/physiology; Body Temperature/*physiology; Circadian Rhythm/*physiology; Female; Horses/*physiology; Melatonin/blood/*physiology; Motor Activity/*physiology; Rectum/physiology; Sheep/*physiology; Time Factors |
|
| |
Abstract |
Daily or circadian oscillation has been documented in a variety of physiological and behavioral processes. Although individual variables have been studied in great detail, very few studies have been conducted on the temporal relationships between the rhythms of different variables. It is not known whether the circadian pacemaker generates each and every rhythm individually or whether most rhythms are simply derived from a few clock-controlled rhythms. As a first step in elucidating this issue, 21 physiological variables were recorded simultaneously in horse and sheep. The results indicated that, in both species, different variables exhibit different degrees of daily rhythmicity and reach their daily peaks at different times of the day. The variables exhibiting strongest rhythmicity were locomotor activity, rectal temperature, and plasma concentrations of melatonin and glucose. Comparison of rhythmicity and acrophase in the various rhythms allowed inferences to be made about mechanisms of causation. |
|
| |
Address |
Dipartimento di Morfologia, Biochimica, Fisiologia e Produzioni Animali, Facolta di Medicina Veterinaria, Universita degli Studi di Messina, 98168 Messina, Italy |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1095-6433 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:16290083 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1884 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Husted, L.; Andersen, M.S.; Borggaard, O.K.; Houe, H.; Olsen, S.N. |
|
| |
Title |
Risk factors for faecal sand excretion in Icelandic horses |
Type |
Journal Article |
| |
Year |
2005 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
|
| |
Volume |
37 |
Issue |
4 |
Pages |
351-355 |
|
| |
Keywords |
Animal Feed; Animal Husbandry/methods; Animals; Denmark; Feces/*chemistry; Female; Gastrointestinal Diseases/epidemiology/etiology/prevention & control/veterinary; Horse Diseases/epidemiology/etiology/prevention & control; Horses/*metabolism; Logistic Models; Male; Pilot Projects; *Poaceae/growth & development; Risk Factors; Silicon Dioxide/administration & dosage/adverse effects/*analysis; Soil/*analysis |
|
| |
Abstract |
REASONS FOR PERFORMING STUDY: Sandy soil is often mentioned as a risk factor in the development of sand-related gastrointestinal disease (SGID) in the horse. There are other variables, but few studies confirm any of these. OBJECTIVE: To investigate soil type, pasture quality, feeding practice in the paddock, age, sex and body condition score as risk factors for sand intake in the horse. METHODS: Faeces were collected from 211 Icelandic horses on 19 different studs in Denmark together with soil samples and other potential risk factors. Sand content in faeces determined by a sand sedimentation test was interpreted as evidence of sand intake. Soil types were identified by soil analysis and significance of the data was tested using logistic analysis. RESULTS: Of horses included in the study, 56.4% showed sand in the faeces and 5.7% had more than 5 mm sand as quantified by the rectal sleeve sedimentation test. Soil type had no significant effect when tested as main effect, but there was interaction between soil type and pasture quality. Significant interactions were also found between paddock feeding practice and pasture quality. CONCLUSION: To evaluate the risk of sand intake it is important to consider 3 variables: soil type, pasture quality and feeding practice. Pasture quality was identified as a risk factor of both short and long grass in combination with sandy soil, while clay soil had the lowest risk in these combinations. Feeding practice in the paddock revealed feeding directly on the ground to be a risk factor when there was short (1-5 cm) or no grass. Also, no feeding outdoors increased the risk on pastures with short grass, while this had no effect in paddocks with no grass. More than 50% of all horses investigated in this study had sand in the faeces. POTENTIAL RELEVANCE: The identification of risk factors is an important step towards prevention of SGID. Further research is necessary to determine why some horses exhibit more than 5 mm sand in the sedimentation test and whether this is correlated with geophagic behaviour. |
|
| |
Address |
Department of Large Animal Sciences, The Royal Veterinary and Agricultural University, Dyrlaegevej 88, DK-1870 Frederiksberg, Denmark |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0425-1644 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:16028626 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1888 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Pritchard, J.C.; Lindberg, A.C.; Main, D.C.J.; Whay, H.R. |
|
| |
Title |
Assessment of the welfare of working horses, mules and donkeys, using health and behaviour parameters |
Type |
Journal Article |
| |
Year |
2005 |
Publication |
Preventive Veterinary Medicine |
Abbreviated Journal |
Prev Vet Med |
|
| |
Volume |
69 |
Issue |
3-4 |
Pages |
265-283 |
|
| |
Keywords |
*Animal Welfare; Animals; Behavior, Animal; Developing Countries; *Equidae; Female; Health; Male |
|
| |
Abstract |
Working animals provide an essential transport resource in developing countries worldwide. Many of these animals are owned by poor people and work in harsh environments, so their welfare is a cause for concern. A protocol was developed to assess the welfare of working horses, mules and donkeys in urban and peri-urban areas, using direct observation of health and behaviour parameters. In this study, 4903 animals used for draught, pack and ridden work in Afghanistan, Egypt, India, Jordan and Pakistan were assessed between December 2002 and April 2003. The data showed that donkeys were more likely than mules or horses to demonstrate avoidance or aggressive behaviour towards an observer, while horses were most likely to make a friendly approach. Fewer than 8% of working equines had abnormal mucous membranes, ectoparasites or poor coat condition. Body lesions occurred predominantly in the areas of the breast/shoulder, withers and girth in all three species, with mules having the highest prevalence of lesions in these areas (22.5, 21.3 and 28.4%, respectively). Among horses and donkeys, the prevalence of these lesions was influenced by the type of work carried out. Lesions on the head, neck, ribs, flank and tail base were seen in less than 10% of animals. Across all three species approximately 70% of animals were thin, having a body condition score (BCS) of 2 or less on a scale of 1-5 (1, very thin; 5, very fat) and more horses were in very thin condition (BCS 1) than mules or donkeys. Over 75% of animals demonstrated limb deformities and abnormalities of gait. The results of this study are being used as the initial stage of a long-term strategy to inform priorities for welfare interventions in working equines and to establish a welfare benchmark. Subsequent stages will rank the welfare concerns identified, assess the contributing risk factors and implement specific interventions to address these risks. Following intervention, success in improving welfare will be measured by repetition of this protocol and comparison with the benchmark. |
|
| |
Address |
Department of Clinical Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU, UK. joy.pritchard@bristol.ac.uk |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0167-5877 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15907574 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1889 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Grogan, E.H.; McDonnell, S.M. |
|
| |
Title |
Behavioral responses to two intranasal vaccine applicators in horses and ponies |
Type |
|
| |
Year |
2005 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
|
| |
Volume |
226 |
Issue |
10 |
Pages |
1689-1693 |
|
| |
Keywords |
Administration, Intranasal; Animals; *Behavior, Animal; Female; Horses/physiology/*psychology; Immunization/instrumentation/methods/*veterinary; Male; Patient Compliance/psychology; Physical Examination/psychology/*veterinary; Vaccines/*administration & dosage; Videotape Recording |
|
| |
Abstract |
OBJECTIVE: To evaluate behavioral compliance of horses and ponies with simulated intranasal vaccination and assess development of generalized aversion to veterinary manipulations. DESIGN: Clinical trial. ANIMALS: 28 light horse mares, 3 pony geldings, 2 light horse stallions, and 3 pony stallions that had a history of compliance with veterinary procedures. PROCEDURE: Behavioral compliance with 2 intranasal vaccine applicators was assessed. Compliance with standard physical examination procedures was assessed before and after a single experience with either of the applicators or a control manipulation to evaluate development of generalized aversion to veterinary manipulation. RESULTS: In all 30 horses, simulated intranasal vaccination or the control manipulation could be performed without problematic avoidance behavior, and simulated intranasal vaccination did not have any significant effect on duration of or compliance with a standardized physical examination that included manipulation of the ears, nose, and mouth. Results were similar for the 2 intranasal vaccine applicators, and no difference in compliance was seen between horses in which warm versus cold applicators were used. For 3 of the 6 ponies, substantial avoidance behavior was observed in association with simulated intranasal vaccination, and compliance with physical examination procedures decreased after simulated intranasal vaccination. CONCLUSIONS AND CLINICAL RELEVANCE: Although some compliance problems were seen with ponies, neither problems with compliance with simulated intranasal vaccination nor adverse effects on subsequent physical examination were identified in any of the horses. Further study is needed to understand factors involved in practitioner reports of aversion developing in association with intranasal vaccination. |
|
| |
Address |
Equine Behavior Laboratory, New Bolton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square, PA 19348, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0003-1488 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15906570 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1890 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Davies, H.M.S. |
|
| |
Title |
The timing and distribution of strains around the surface of the midshaft of the third metacarpal bone during treadmill exercise in one Thoroughbred racehorse |
Type |
Journal Article |
| |
Year |
2005 |
Publication |
Australian Veterinary Journal |
Abbreviated Journal |
Aust Vet J |
|
| |
Volume |
83 |
Issue |
3 |
Pages |
157-162 |
|
| |
Keywords |
Animals; Exercise Test/veterinary; Female; Gait/*physiology; Horses/*physiology; Metacarpus/*physiology; Motor Activity/physiology; Physical Conditioning, Animal/*physiology; Stress, Mechanical; Weight-Bearing/physiology |
|
| |
Abstract |
OBJECTIVE: To confirm that the midshaft dorsal cortex of the third metacarpal bone experienced higher compressive strains during fast exercise than the medial or lateral cortices, and that the strain peak occurred earlier in the hoof-down phase of the stride on the dorsal cortex than the medial or lateral cortices. DESIGN: Observations of a single horse. PROCEDURE: Strains were collected from a single, sound, 3-year-old Thoroughbred mare during treadmill exercise from rosette strain gauges implanted onto the medial, lateral and dorsal surfaces of the midshaft of the right cannon bone, simultaneously with data from a hoof switch that showed when the hoof was in the stance phase. RESULTS: Peak compressive strains on the dorsal surface of the third metacarpal bone were proportional to exercise speed and occurred at about 30% of stance. Peak compressive strains on the medial surface of the non-lead limb reached a maximum at a speed around 10 m/s and occurred at mid-stance. Peak compressive strains on the lateral surface varied in timing and size between strides at all exercise speeds, but remained less than -2000 microstrains. CONCLUSIONS: The timing of peak compressive strains on the dorsal cortex suggests a relationship to deceleration of the limb following hoof impact, so the main determinants of their size would be exercise speed and turning (as shown in previous experiments). This experiment confirms data from other laboratories that were published but not discussed, that peak compressive strains on the medial surface occur at mid-stance. This suggests that they are related to the support of body weight. The strains on the lateral cortex occurred at variable times so may be associated with the maintenance of balance as well as the support of body weight. Understanding the loading of the third metacarpal bone will help to determine causes of damage to it and ways in which the bone might be conditioned to prevent such damage. |
|
| |
Address |
Department of Veterinary Science, University of Melbourne, Parkville, Victoria 3010. h.davies@unimelb.edu.au |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0005-0423 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15825628 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1891 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Hausberger, M.; Bruderer, C.; Le Scolan, N.; Pierre, J.-S. |
|
| |
Title |
Interplay between environmental and genetic factors in temperament/personality traits in horses (Equus caballus) |
Type |
Journal Article |
| |
Year |
2004 |
Publication |
Journal of Comparative Psychology |
Abbreviated Journal |
J Comp Psychol |
|
| |
Volume |
118 |
Issue |
4 |
Pages |
434-446 |
|
| |
Keywords |
*Affect; Animals; Behavior, Animal/*physiology; *Environment; Female; Horses/*psychology; Learning; Male; Memory/physiology |
|
| |
Abstract |
The aim of the present study was to broach the question of the relative influence of different genetic and environmental factors on different temperament/personality traits of horses (Equus caballus). The researchers submitted 702 horses to standardized experimental tests and investigated 9 factors, either genetic or environmental. Genetic factors, such as sire or breed, seemed to influence more neophobic reactions, whereas environmental factors, such as the type of work, seemed to play a more dominant role in reactions to social separation or learning abilities. Additive effects were evident, showing how environmental factors may modulate behavioral traits. This study constitutes a first step toward understanding the relative weights of genetic factors and how the environment may intervene in determining individual behavioral characteristics. |
|
| |
Address |
Ethologie-Evolution-Ecologie, Universite de Rennes 1, Rennes, France. Martine.Hausberger@univ-rennes1.fr |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
Washington, D.C. : 1983 |
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0735-7036 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15584780 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1897 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Rietmann, T.R.; Stauffacher, M.; Bernasconi, P.; Auer, J.A.; Weishaupt, M.A. |
|
| |
Title |
The association between heart rate, heart rate variability, endocrine and behavioural pain measures in horses suffering from laminitis |
Type |
Journal Article |
| |
Year |
2004 |
Publication |
Journal of Veterinary Medicine. A, Physiology, Pathology, Clinical Medicine |
Abbreviated Journal |
J Vet Med A Physiol Pathol Clin Med |
|
| |
Volume |
51 |
Issue |
5 |
Pages |
218-225 |
|
| |
Keywords |
Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Autonomic Nervous System; Behavior, Animal; Electrophysiology/*methods; Endocrine System; Female; Heart Rate; Horse Diseases/blood/drug therapy/*physiopathology; Horses; Joint Diseases/physiopathology/*veterinary; Male; Pain/physiopathology/*veterinary; Pain Measurement/*veterinary; Predictive Value of Tests |
|
| |
Abstract |
The objective of this study was to compare the stress response of horses suffering from laminitis after short- and long-term treatment with the intent to evaluate power spectral analysis of heart rate variability (HRV) for pain monitoring. Data were collected from 19 horses with acute or chronic exacerbating laminitis without known primary disease before and after treatment with non-steroidal anti-inflammatory drugs (NSAID). Recordings were carried out the day after admission to the equine hospital. Measurements were repeated on day 7 of the treatment. The recorded parameters included a clinical orthopaedic index (OLPI: Obel-grade plus hoof tester score), frequency of weight-shifting between contralateral limbs, mean beat-to-beat interval (R-R) duration, standard deviation of continuous R-R intervals, low- (LF) and high-frequency (HF) components of HRV, sympatho-vagal balance (LF/HF), and plasma concentration of cortisol, adrenalin and noradrenalin. The LF represents mainly sympathetic influences on the heart whereas HF is mediated by the parasympathetic tone. Weight-shifting and OLPI decreased significantly with treatment. The LF normalized units (n.u.) decreased after NSAID from 60.41 +/- 21.42 to 51.12 +/- 19.81 and was 49.33 +/- 22.64 on day 7, whereas HF n.u. increased from 35.07 +/- 20.02 to 43.14 +/- 18.30 and was 45.98 +/- 23.00 on day 7. Hormone levels showed no tendency to change with treatment. The OLPI was only correlated with LF/HF, LF and HF (R = 0.57, 0.55 and -0.54 respectively). Significant negative correlations existed between HFn.u. and weight-shifting frequency (R = -0.37), HFn.u. and adrenalin (R = -0.47), and HFn.u. and noradrenalin (R = 0.33). The LFn.u. only correlated positively with adrenalin. Cortisol levels were poorly associated with the other parameters. Determination of the sympatho-vagal influences on cardiac function may offer complementary information for reliable assessment of pain and may represent a valuable alternative method to catecholamine measurements. |
|
| |
Address |
Equine Hospital, Faculty of Veterinary Medicine, University of Zurich, Winterthurerstrasse 260, CH-8057 Zurich, Switzerland |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0931-184X |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15315700 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1899 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Zeitler-Feicht, M.H. |
|
| |
Title |
[Critical consideration of the “Guideline for the Evaluation of Raising Horses” and keeping horses outside in the winter] |
Type |
Journal Article |
| |
Year |
2004 |
Publication |
DTW. Deutsche Tierarztliche Wochenschrift |
Abbreviated Journal |
Dtsch Tierarztl Wochenschr |
|
| |
Volume |
111 |
Issue |
3 |
Pages |
120-123 |
|
| |
Keywords |
Animal Feed/standards; Animal Husbandry/legislation & jurisprudence/methods/*standards; *Animal Welfare/legislation & jurisprudence; Animals; Cold; Female; Germany; Guidelines/*standards; Horses/*physiology; Housing, Animal/legislation & jurisprudence/*standards; Legislation, Veterinary; Male; Seasons |
|
| |
Abstract |
The guidelines of the Federal Ministry of User Protection, Nutrition and Agriculture (BMVEL) regarding “horse keeping with respect to animal welfare” are from 1995 (BMELF, 1995). Therefore, they are not suitable for modern horse keeping. The Veterinary Association for Animal Welfare (TVT) held it to be necessary to rework the guide-lines in light of 1) many subsequent investigations concerning horse keeping, and 2) the species-specific needs of horses in practice. Each chapter of the BMELF (1995) guide-lines was revised such that the literature and practical experiences were updated. Several chapters (recumbency resting behaviour, fences, underground outdoor and in stables, litter) were added in the position paper of the TVT to reflect the increasing use of boxes with paddocks, loose housing systems with open yards, pasture and winter yards as housing conditions. Keeping horses outdoors permanently during winter is possible because horses have very good thermoregulatory capabilities so that they are able to adapt themselves to cold conditions. However, in light of animal welfare, the holding system must include adequate shelter (natural or artificial). Shelters should protect against wetness, heat, cold and wind, and must be sufficiently large and high, with a dry and clean underground. In keeping horses outdoors permanently, the paths to the feeding and watering areas and to the shelter must be dry. The food must also be protected against mould and soiling. Keeping horses permanently without adequate shelter or in deep marsh without any dry places is against the Animal Protection Act. |
|
| |
Address |
Lehrgebiet fur Tierhaltung und Verhaltenskunde, Wissenschaftszentrum Weihenstephan fur Ernahrung, Landnutzung und Umwelt, Technische Universitat Munchen. Zeitler-Feicht@tz.agrar.tu-muenchen.de |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
German |
Summary Language |
|
Original Title |
Kritische Betrachtung der “Leitlinien zur Beurteilung von Pferdehaltungen” und Winteraussenhaltung von Pferden |
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0341-6593 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15195962 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1900 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Dirikolu, L.; Lehner, A.F.; Karpiesiuk, W.; Hughes, C.; Woods, W.E.; Boyles, J.; Harkins, J.D.; Troppmann, A.; Tobin, T. |
|
| |
Title |
Detection, quantification, metabolism, and behavioral effects of selegiline in horses |
Type |
Journal Article |
| |
Year |
2003 |
Publication |
Veterinary Therapeutics : Research in Applied Veterinary Medicine |
Abbreviated Journal |
Vet Ther |
|
| |
Volume |
4 |
Issue |
3 |
Pages |
257-268 |
|
| |
Keywords |
Administration, Oral; Animals; Behavior, Animal/drug effects; Female; Horses/*metabolism; Mass Spectrometry/veterinary; Monoamine Oxidase Inhibitors/administration & dosage/blood/*pharmacokinetics/pharmacology/urine; Selegiline/administration & dosage/blood/*pharmacokinetics/pharmacology/urine; Substance Abuse Detection/veterinary |
|
| |
Abstract |
Selegiline ([R]-[-]N,alpha-dimethyl-N-2- propynylphenethylamine or l-deprenyl), an irreversible inhibitor of monoamine oxidase, is a classic antidyskinetic and antiparkinsonian agent widely used in human medicine both as monotherapy and as an adjunct to levodopa therapy. Selegiline is classified by the Association of Racing Commissioners International (ARCI) as a class 2 agent, and is considered to have high abuse potential in racing horses. A highly sensitive LC/MS/MS quantitative analytical method has been developed for selegiline and its potential metabolites amphetamine and methamphetamine using commercially available deuterated analogs of these compounds as internal standards. After administering 40 mg of selegiline orally to two horses, relatively low (<60 ng/ml) concentrations of parent selegiline, amphetamine, and methamphetamine were recovered in urine samples. However, relatively high urinary concentrations of another selegiline metabolite were found, tentatively identified as N- desmethylselegiline. This metabolite was synthesized and found to be indistinguishable from the new metabolite recovered from horse urine, thereby confirming the chemical identity of the equine metabolite. Additionally, analysis of urine samples from four horses dosed with 50 mg of selegiline confirmed that N-desmethylselegiline is the major urinary metabolite of selegiline in horses. In related behavior studies, p.o. and i.v. administration of 30 mg of selegiline produced no significant changes in either locomotor activities or heart rates. |
|
| |
Address |
Department of Biomedical Sciences, College of Veterinary Medicine, Nursing and Allied Health, Tuskegee University, Tuskegee, AL 36088, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
1528-3593 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15136987 |
Approved |
no |
|
| |
Call Number |
|
Serial |
1901 |
|
| Permanent link to this record |
