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Author |
Brown, R.F.; Houpt, K.A.; Schryver, H.F. |
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Title |
Stimulation of food intake in horses by diazepam and promazine |
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Journal Article |
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Year |
1976 |
Publication |
Pharmacology, biochemistry, and behavior |
Abbreviated Journal |
Pharmacol Biochem Behav |
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Volume |
5 |
Issue |
4 |
Pages |
495-497 |
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Keywords |
Age Factors; Animals; Diazepam/*pharmacology; Diet; Feeding Behavior/*drug effects; Female; Horses/*physiology; Male; Promazine/*pharmacology; Stimulation, Chemical |
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Abstract |
In two adult horses doses of 0.02-0.03 mg/kg diazepam, intravenously, increased 1 hr intake 54-75% above control levels. Intake was stimulated when the diet was a high grain, calorically dense one and also when the diet was a high fiber, calorically dilute one. Two young rapidly growing weanling horses showed an even more pronounced stimulation of intake. Following diazepam 1 hr intake was increased 105-240% above control lelvels. Promazine at a dose of 0.5 mg/kg also stimulated intake in adult horses, but not as markedly as did diazepam. A transquilizer and a neuroleptic appear to have a stimulatory eff upon short-term intake in horses. |
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English |
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0091-3057 |
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PMID:1005496 |
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Call Number |
refbase @ user @ |
Serial |
60 |
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Author |
Houpt, T.R.; Houpt, K.A. |
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Title |
Nitrogen conservation by ponies fed a low -protein ration |
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Journal Article |
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Year |
1971 |
Publication |
American journal of veterinary research |
Abbreviated Journal |
Am J Vet Res |
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Volume |
32 |
Issue |
4 |
Pages |
579-588 |
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Keywords |
Administration, Oral; Amino Acids/biosynthesis; Animals; Anti-Infective Agents/pharmacology; Body Weight/drug effects; Dietary Proteins/*pharmacology; Horses/*metabolism; Nitrogen/*metabolism; Urea/administration & dosage/antagonists & inhibitors/metabolism; Water/metabolism |
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English |
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0002-9645 |
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Notes |
PMID:5110116 |
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Call Number |
refbase @ user @ |
Serial |
62 |
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Author |
Jeong, S.; Han, M.; Lee, H.; Kim, M.; Kim, J.; Nicol, C.J.; Kim, B.H.; Choi, J.H.; Nam, K.-H.; Oh, G.T.; Yoon, M. |
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Title |
Effects of fenofibrate on high-fat diet-induced body weight gain and adiposity in female C57BL/6J mice |
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Journal Article |
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Year |
2004 |
Publication |
Metabolism: clinical and experimental |
Abbreviated Journal |
Metabolism |
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Volume |
53 |
Issue |
10 |
Pages |
1284-1289 |
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Keywords |
Adipose Tissue/*anatomy & histology/drug effects; Animals; Antilipemic Agents/*pharmacology; Body Composition/*drug effects; Body Weight/drug effects; Dietary Fats/*pharmacology; Eating/drug effects; Fatty Acids/metabolism; Female; Gene Expression Regulation/drug effects; Leptin/metabolism; Liver/metabolism; Mice; Mice, Inbred C57BL; Ovariectomy; Procetofen/*pharmacology; RNA, Messenger/biosynthesis/genetics; Receptors, Cytoplasmic and Nuclear/biosynthesis/genetics/metabolism; Transcription Factors/biosynthesis/genetics/metabolism; Weight Gain/*drug effects |
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Abstract |
Our previous study suggested that fenofibrate affects obesity and lipid metabolism in a sexually dimorphic manner in part through the differential activation of hepatic peroxisome proliferator-activated receptor alpha (PPARalpha) in male and female C57BL/6J mice. To determine whether fenofibrate reduces body weight gain and adiposity in female sham-operated (Sham) and ovariectomized (OVX) C57BL/6J mice, the effects of fenofibrate on not only body weight, white adipose tissue (WAT) mass, and food intake, but also the expression of both leptin and PPARalpha target genes were measured. Compared to their respective low-fat diet-fed controls, both Sham and OVX mice exhibited increases in body weight and WAT mass when fed a high-fat diet. Fenofibrate treatment decreased body weight gain and WAT mass in OVX, but not in Sham mice. Furthermore, fenofibrate increased the mRNA levels of PPARalpha target genes encoding peroxisomal enzymes involved in fatty acid beta-oxidation, and reduced apolipoprotein C-III (apo C-III) mRNA, all of which were expressed at higher levels in OVX compared to Sham mice. However, leptin mRNA levels were found to positively correlate with WAT mass, and food intake was not changed in either OVX or Sham mice following fenofibrate treatment. These results suggest that fenofibrate differentially regulates body weight and adiposity due in part to differences in PPARalpha activation, but not to differences in leptin production, between female OVX and Sham mice. |
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Department of Life Sciences, Mokwon University, Taejon, Korea |
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ISSN |
0026-0495 |
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Notes |
PMID:15375783 |
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Call Number |
refbase @ user @ |
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72 |
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Author |
Nelson, G.S. |
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Title |
Onchocerciasis |
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Journal Article |
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Year |
1970 |
Publication |
Advances in Parasitology |
Abbreviated Journal |
Adv Parasitol |
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Volume |
8 |
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173-224 |
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Keywords |
Africa; Animals; Anthelmintics/therapeutic use; Artiodactyla; Blindness/etiology; Cattle; Circadian Rhythm; Ddt; Diethylcarbamazine/therapeutic use; Diptera/anatomy & histology/growth & development; Dwarfism/etiology; Ecology; Eye/pathology; Feeding Behavior; Female; Geography; Haplorhini; Hernia, Femoral/etiology; Horses; Humans; Insect Vectors/growth & development; Larva/growth & development; Male; Onchocerca/classification/growth & development; *Onchocerciasis/diagnosis/drug therapy/epidemiology/immunology/pathology/prevention & control/veterinary; Primates; Serologic Tests; Skin/pathology; Skin Tests; Suramin/therapeutic use |
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English |
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0065-308X |
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Notes |
PMID:4997515 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2738 |
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Author |
Milgram, N.W.; Head, E.; Muggenburg, B.; Holowachuk, D.; Murphey, H.; Estrada, J.; Ikeda-Douglas, C.J.; Zicker, S.C.; Cotman, C.W. |
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Title |
Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy |
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Journal Article |
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Year |
2002 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
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Volume |
26 |
Issue |
6 |
Pages |
679-695 |
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Keywords |
Age Factors; Aging/*physiology; Analysis of Variance; Animals; Antioxidants/*pharmacology; Blood Chemical Analysis/methods; Cognition/*physiology; *Diet; Discrimination Learning/*drug effects/*physiology; Distance Perception/drug effects/physiology; Dogs/physiology; Female; Male; Psychomotor Performance/physiology; Retention (Psychology)/drug effects/physiology; Spatial Behavior/*drug effects/*physiology; Task Performance and Analysis; Time Factors; Vitamin E/blood |
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Abstract |
The landmark discrimination learning test can be used to assess the ability to utilize allocentric spatial information to locate targets. The present experiments examined the role of various factors on performance of a landmark discrimination learning task in beagle dogs. Experiments 1 and 2 looked at the effects of age and food composition. Experiments 3 and 4 were aimed at characterizing the cognitive strategies used in performance on this task and in long-term retention. Cognitively equivalent groups of old and young dogs were placed into either a test group maintained on food enriched with a broad-spectrum of antioxidants and mitochondrial cofactors, or a control group maintained on a complete and balanced food formulated for adult dogs. Following a wash-in period, the dogs were tested on a series of problems, in which reward was obtained when the animal responded selectively to the object closest to a thin wooden block, which served as a landmark. In Experiment 1, dogs were first trained to respond to a landmark placed directly on top of coaster, landmark 0 (L0). In the next phase of testing, the landmark was moved at successively greater distances (1, 4 or 10 cm) away from the reward object. Learning varied as a function of age group, food group, and task. The young dogs learned all of the tasks more quickly than the old dogs. The aged dogs on the enriched food learned L0 significantly more rapidly than aged dogs on control food. A higher proportion of dogs on the enriched food learned the task, when the distance was increased to 1cm. Experiment 2 showed that accuracy decreased with increased distance between the reward object and landmark, and this effect was greater in old animals. Experiment 3 showed stability of performance, despite using a novel landmark, and new locations, indicating that dogs learned the landmark concept. Experiment 4 found age impaired long-term retention of the landmark task. These results indicate that allocentric spatial learning is impaired in an age-dependent manner in dogs, and that age also affects performance when the distance between the landmark and target is increased. In addition, these results both support a role of oxidative damage in the development of age-associated cognitive dysfunction and indicate that short-term administration of a food enriched with supplemental antioxidants and mitochondrial cofactors can partially reverse the deleterious effects of aging on cognition. |
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Address |
Life Science Division, University of Toronto at Scarborough, 1265 Military Trail, Scarborough, Ont., Canada M1C 1A4. milgram@psych.utoronto.ca |
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English |
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ISSN |
0149-7634 |
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Notes |
PMID:12479842 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2806 |
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Author |
Cowley, J.J.; Griesel, R.D. |
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Title |
The effect on growth and behaviour of rehabilitating first and second generation low protein rats |
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Journal Article |
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Year |
1966 |
Publication |
Animal Behaviour. |
Abbreviated Journal |
Anim. Behav. |
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Volume |
14 |
Issue |
4 |
Pages |
506-517 |
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Keywords |
Animals; *Behavior, Animal; Diet Therapy; Dietary Proteins; Female; *Growth; Humans; Intelligence; Learning; Male; Mental Retardation/etiology; Protein Deficiency/*therapy; Rats |
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English |
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ISSN |
0003-3472 |
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Notes |
PMID:6008473 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4119 |
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Author |
Griffin, B. |
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Title |
The use of fecal markers to facilitate sample collection in group-housed cats |
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Journal Article |
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Year |
2002 |
Publication |
Contemporary Topics in Laboratory Animal Science / American Association for Laboratory Animal Science |
Abbreviated Journal |
Contemp Top Lab Anim Sci |
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Volume |
41 |
Issue |
2 |
Pages |
51-56 |
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Keywords |
Animals; Behavior, Animal; Biological Markers/*analysis; Cats/*physiology/psychology; Diet/veterinary; Feces/*chemistry; Food Coloring Agents/analysis; Housing, Animal; Individuality; Plastics/analysis; Specimen Handling/methods/*veterinary |
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Abstract |
The provision of proper social housing is a priority when designing an experiment using domestic cats as laboratory animals. When animals are group-housed, studies requiring analysis of stool samples from individual subjects pose difficulty in sample collection and identification. In this study, commercially available concentrated food colorings (known as bakers pastes) were used as fecal markers in group-housed cats. Cats readily consumed 0.5 ml of bakers paste food coloring once daily in canned cat food. Colorings served as fecal markers by imparting a distinct color to each cat s feces, allowing identification in the litter box. In addition, colored glitter (1/8 teaspoon in canned food) was fed to cats and found to be a reliable fecal marker. Long-term feeding of colorings and glitter was found to be safe and effective at yielding readily identifiable stools. |
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Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Alabama 36841, USA |
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ISSN |
1060-0558 |
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Notes |
PMID:11958604 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4165 |
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