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Author |
Carroll, G.L.; Matthews, N.S.; Hartsfield, S.M.; Slater, M.R.; Champney, T.H.; Erickson, S.W. |
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Title |
The effect of detomidine and its antagonism with tolazoline on stress-related hormones, metabolites, physiologic responses, and behavior in awake ponies |
Type |
Journal Article |
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Year |
1997 |
Publication |
Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons |
Abbreviated Journal |
Vet Surg |
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Volume  |
26 |
Issue |
1 |
Pages |
69-77 |
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Keywords |
Adrenergic alpha-Antagonists/administration & dosage/*pharmacology; Animals; Behavior, Animal/drug effects/physiology; Blood Glucose/metabolism; Blood Pressure/drug effects/physiology; Consciousness/physiology; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine/blood; Fatty Acids, Nonesterified/blood; Female; Heart Rate/drug effects/physiology; Horse Diseases/metabolism/physiopathology/psychology; Horses/blood/metabolism/*physiology; Hydrocortisone/blood; Hypnotics and Sedatives/administration & dosage/*pharmacology; Imidazoles/administration & dosage/*pharmacology; Injections, Intravenous; Male; Norepinephrine/blood; Receptors, Adrenergic, alpha/drug effects/*physiology; Stress/metabolism/physiopathology/veterinary; Time Factors; Tolazoline/administration & dosage/*pharmacology |
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Abstract |
Six ponies were used to investigate the effect of tolazoline antagonism of detomidine on physiological responses, behavior, epinephrine, norepinephrine, cortisol, glucose, and free fatty acids in awake ponies. Each pony had a catheter inserted into a jugular vein 1 hour before beginning the study. Awake ponies were administered detomidine (0.04 mg/kg intravenously [i.v.]) followed 20 minutes later by either tolazoline (4.0 mg/kg i.v.) or saline. Blood samples were drawn from the catheter 5 minutes before detomidine administration (baseline), 5 minutes after detomidine administration, 20 minutes before detomidine administration which was immediately before the administration of tolazoline or saline (time [T] = 0), and at 5, 30, and 60 minutes after injections of tolazoline or saline (T = 5, 30, and 60 minutes, respectively). Compared with heart rate at T = 0, tolazoline antagonism increased heart rate 45% at 5 minutes. There was no difference in heart rate between treatments at 30 minutes. Blood pressure remained stable after tolazoline, while it decreased over time after saline. Compared with concentrations at T = 0, tolazoline antagonism of detomidine in awake ponies resulted in a 55% increase in cortisol at 30 minutes and a 52% increase in glucose at 5 minutes. The change in free fatty acids was different for tolazoline and saline over time. Free fatty acids decreased after detomidine administration. Free fatty acids did not change after saline administration. After tolazoline administration, free fatty acids increased transiently. Tolazoline tended to decrease sedation and analgesia at 15 and 60 minutes postantagonism. Antagonism of detomidine-induced physiological and behavioral effects with tolazoline in awake ponies that were not experiencing pain appears to precipitate a stress response as measured by cortisol, glucose, and free fatty acids. If antagonism of an alpha-agonist is contemplated, the potential effect on hormones and metabolites should be considered. |
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Department of Small Animal Medicine and Surgery, Texas A&M University, College Station, USA |
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ISSN |
0161-3499 |
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Notes |
PMID:9123816 |
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no |
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Call Number |
refbase @ user @ |
Serial |
96 |
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Author |
Iwuala, M.O.; Okpala, I. |
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Title |
Studies on the ectoparasitic fauna of Nigerian livestock II: Seasonal infestation rates |
Type |
Journal Article |
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Year |
1978 |
Publication |
Bulletin of Animal Health and Production in Africa. Bulletin des Sante et Production Animales en Afrique |
Abbreviated Journal |
Bull Anim Health Prod Afr |
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Volume |
26 |
Issue |
4 |
Pages |
351-359 |
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Keywords |
Animal Diseases/*epidemiology; Animals; Cattle; Dogs; Ecology; Ectoparasitic Infestations/epidemiology/*veterinary; Goats; Horses; Nigeria; Seasons; Sheep; Swine |
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ISSN |
0378-9721 |
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Notes |
PMID:756759 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2695 |
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Author |
Iwuala, M.O.; Okpala, I. |
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Title |
Studies on the ectoparasitic fauna of Nigerian livestock I: Types and distribution patterns on hosts' |
Type |
Journal Article |
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Year |
1978 |
Publication |
Bulletin of Animal Health and Production in Africa. Bulletin des Sante et Production Animales en Afrique |
Abbreviated Journal |
Bull Anim Health Prod Afr |
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Volume |
26 |
Issue |
4 |
Pages |
339-350 |
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Keywords |
Animal Diseases/*epidemiology; Animals; Cattle; Dogs; Ecology; Ectoparasitic Infestations/epidemiology/*veterinary; Goats; Horses; Nigeria; Sheep; Swine |
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English |
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0378-9721 |
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Notes |
PMID:756758 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2696 |
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Author |
Munoz-Sanz, A. |
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Title |
[Christopher Columbus flu. A hypothesis for an ecological catastrophe] |
Type |
Journal Article |
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Year |
2006 |
Publication |
Enfermedades Infecciosas y Microbiologia Clinica |
Abbreviated Journal |
Enferm Infecc Microbiol Clin |
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Volume |
24 |
Issue |
5 |
Pages |
326-334 |
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Keywords |
Animals; Atlantic Islands; Birds; Chickens; Disease Outbreaks/*history; Disease Reservoirs; Disease Susceptibility; Ecology; Europe/ethnology; History, 15th Century; Horses; Humans; Indians, South American; Influenza A virus/classification/genetics/pathogenicity; Influenza in Birds/epidemiology/history/transmission/virology; Influenza, Human/epidemiology/*history/mortality/transmission; Models, Biological; Orthomyxoviridae Infections/epidemiology/history/veterinary/virology; Poultry Diseases/epidemiology/history/transmission/virology; Reassortant Viruses/genetics/pathogenicity; Species Specificity; Sus scrofa; Swine Diseases/history/transmission/virology; Terminology; West Indies/epidemiology |
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Abstract |
When Christopher Columbus and his men embarked on the second Colombian expedition to the New World (1493), the crew suffered from fever, respiratory symptoms and malaise. It is generally accepted that the disease was influenza. Pigs, horses and hens acquired in Gomera (Canary Islands) traveled in the same ship. The pigs may well have been the origin of the flu and the intermediary hosts for genetic recombination of other viral subtypes. The Caribbean archipelago had a large population of birds, the natural reservoir of the avian influenza virus. In this ecological scenario there was a concurrence of several biological elements that had never before coexisted in the New World: pigs, horses, the influenza virus and humans. We propose that birds are likely to have played an important role in the epidemiology of the flu occurring on the second Colombian trip, which caused a fatal demographic catastrophe, with an estimated mortality of 90% among the natives. |
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Address |
Unidad de Patologia Infecciosa, Hospital Universitario Infanta Cristina, Servicio Extremeno de Salud, Universidad de Extremadura, Badajoz, Espana. infectio@unex.es |
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Spanish |
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Original Title |
La gripe de Cristobal Colon. Hipotesis sobre una catastrofe ecologica |
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Series Volume |
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Edition |
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ISSN |
0213-005X |
ISBN |
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Expedition |
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Conference |
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Notes |
PMID:16762260 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2624 |
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Author |
Carmalt, J.L.; Carmalt, K.P.; Barber, S.M. |
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Title |
The effect of occlusal equilibration on sport horse performance |
Type |
Journal Article |
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Year |
2006 |
Publication |
Journal of Veterinary Dentistry |
Abbreviated Journal |
J Vet Dent |
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Volume |
23 |
Issue |
4 |
Pages |
226-230 |
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Keywords |
Analysis of Variance; Animals; Cross-Over Studies; *Dental Occlusion, Balanced; Horse Diseases/*therapy; Horses; Malocclusion/therapy/*veterinary; Occlusal Adjustment/methods/*veterinary; Prospective Studies; Treatment Outcome |
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Abstract |
The objective of this study was to investigate the effect of routine dental occlusal equilibration treatment on dressage horse performance. Sixteen horses (11 treated; 5 untreated) ridden by a single rider performed a standardized dressage test twice and were scored by two experienced dressage judges according to recognized movements and rider cues. All horses were sedated and a full-mouth speculum was used to facilitate a complete oral examination. Treated horses had dental equilibration performed using a motorized dental instrument. The horses performed a second test 48-hours after dental equilibration, exactly as the baseline test, with the judges and rider blinded as to treatment group. The total test score as well as the individual movement scores were evaluated for equality of variance and statistical tests were applied to determine the influence of treatment. There was no significant improvement in the test score of horses that had received occlusal equilibration. |
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Address |
Scone Veterinary Hospital, NSW, Australia. carmalt_vet@hotmail.com |
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English |
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ISSN |
0898-7564 |
ISBN |
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Notes |
PMID:17286128 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3708 |
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Author |
Gothe, R. |
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Title |
[Tapeworms, a problem in equine practice?] |
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Journal Article |
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Year |
1994 |
Publication |
Tierarztliche Praxis |
Abbreviated Journal |
Tierarztl Prax |
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Volume |
22 |
Issue |
5 |
Pages |
466-470 |
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Keywords |
Animals; Cestode Infections/diagnosis/parasitology/therapy/*veterinary; *Horse Diseases/diagnosis/parasitology/therapy; Horses |
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Abstract |
This paper gives a survey on biology and ecology of equine tapeworms as well as on pathogenesis, clinics, diagnosis, therapy, and prophylaxis of tapeworm infections. |
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Address |
Institut fur Vergleichende Tropenmedizin und Parasitologie, Ludwig-Maximilians-Universitat Munchen |
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Language |
German |
Summary Language |
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Original Title |
Bandwurmer, ein Problem in der Pferdepraxis? |
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Abbreviated Series Title |
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Edition |
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ISSN |
0303-6286 |
ISBN |
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Notes |
PMID:7855855 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2663 |
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Author |
Bast, T.F.; Whitney, E.; Benach, J.L. |
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Title |
Considerations on the ecology of several arboviruses in eastern Long Island |
Type |
Journal Article |
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Year |
1973 |
Publication |
The American Journal of Tropical Medicine and Hygiene |
Abbreviated Journal |
Am J Trop Med Hyg |
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Volume |
22 |
Issue |
1 |
Pages |
109-115 |
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Keywords |
Animals; Antibodies, Viral/analysis; Arboviruses/*isolation & purification; Birds; Brain/microbiology; Ecology; Encephalitis Virus, St. Louis/immunology/isolation & purification; Encephalitis Virus, Western Equine/immunology/isolation & purification; Encephalitis Viruses/immunology/isolation & purification; Encephalitis Viruses, Tick-Borne/immunology/isolation & purification; Encephalomyelitis, Equine/epidemiology/veterinary; Hemagglutination Inhibition Tests; Horse Diseases/epidemiology; Horses; Humans; Insects; Liver/microbiology; Mites; Neutralization Tests; New York; Snakes; Ticks |
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English |
Summary Language |
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Abbreviated Series Title |
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ISSN |
0002-9637 |
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Notes |
PMID:4684881 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2715 |
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Author |
Dabareiner, R.M.; Sullins, K.E.; White, N.A. 2nd |
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Title |
Progression of femoropatellar osteochondrosis in nine young horses. Clinical, radiographic and arthroscopic findings |
Type |
Journal Article |
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Year |
1993 |
Publication |
Veterinary Surgery : VS : the Official Journal of the American College of Veterinary Surgeons |
Abbreviated Journal |
Vet Surg |
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Volume |
22 |
Issue |
6 |
Pages |
515-523 |
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Keywords |
Animals; Arthroscopy/veterinary; Debridement/veterinary; Exudates and Transudates; Female; Femur; Follow-Up Studies; Horse Diseases/*diagnosis/radiography/surgery; Horses; Lameness, Animal/*etiology; Male; Osteochondritis/diagnosis/radiography/surgery/*veterinary; Patella; Stifle; Treatment Outcome |
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Abstract |
The clinical and radiographic progression, and arthroscopic findings for nine young horses (< 1 year of age) with femoropatellar osteochondrosis (OCD) are presented. Horses had a 2 to 12 week history of bilateral (8 horses) or unilateral (1 horse) hindlimb lameness. The most consistent clinical signs included femoropatellar joint distention and bilateral hindlimb lameness. At the onset of clinical signs, radiographic lesions were not present (4 horses) or subtle (5 horses), but were easily identified on radiographs taken 4 to 24 weeks later. Arthroscopic surgery was delayed until radiographic changes became obvious. Surgical findings in 20 femoropatellar joints were most commonly osteochondral “flaps” located on the proximal lateral trochlear ridge of the femur and were larger than had been indicated by the radiographs. Eight horses were being used for their intended purpose, which was racing (3 horses were racing and 3 were in race training), dressage (1 horse) or pleasure riding (1 horse). One horse required a second surgery when similar lesions developed on the opposite stifle, and was euthanatized 2 months later because of persistent lameness. One clinical signs are observed, osteochondrosis lesions of the distal femur can progress in foals younger than 9 months of age and the full extent of the radiographic lesion may take several weeks to develop. |
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Address |
Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, Virginia |
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English |
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Abbreviated Series Title |
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Series Volume |
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Edition |
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ISSN |
0161-3499 |
ISBN |
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Notes |
PMID:8116209 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3748 |
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Author |
Aviad, A.D.; Houpt, J.B. |
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Title |
The molecular weight of therapeutic hyaluronan (sodium hyaluronate): how significant is it? |
Type |
Journal Article |
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Year |
1994 |
Publication |
The Journal of rheumatology |
Abbreviated Journal |
J Rheumatol |
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Volume |
21 |
Issue |
2 |
Pages |
297-301 |
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Keywords |
Animals; Horse Diseases/drug therapy; Horses; Humans; Hyaluronic Acid/*chemistry/*therapeutic use; Joint Diseases/*drug therapy/veterinary; Molecular Weight; Osteoarthritis/drug therapy/veterinary; Synovial Fluid/drug effects/physiology; Viscosity |
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Abstract |
Various molecular weight hyaluronic acid (HA) preparations have been injected into joints for the treatment of human and equine osteoarthritis. A therapeutic advantage has been claimed for commercial products with a molecular weight in the range found in normal synovial fluid (SF), compared to lower molecular weight products. But a correlation between molecular weight and efficacy is not borne out by an analysis of the available literature on clinical results. SF viscosity, HA concentration, HA molecular weight and rate of synthesis in joint disease. It is proposed that the beneficial effect of injected HA in joint disease may be due to pharmacological rather than to physical properties. |
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Address |
Rheumatic Disease Unit, Mount Sinai Hospital, University of Toronto, ON, Canada |
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English |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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ISSN |
0315-162X |
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Notes |
PMID:8182640 |
Approved |
no |
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Call Number |
refbase @ user @ |
Serial |
35 |
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Author |
Dargatz, D.A.; Traub-Dargatz, J.L. |
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Title |
Multidrug-resistant Salmonella and nosocomial infections |
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Journal Article |
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Year |
2004 |
Publication |
The Veterinary Clinics of North America. Equine Practice |
Abbreviated Journal |
Vet Clin North Am Equine Pract |
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Volume |
20 |
Issue |
3 |
Pages |
587-600 |
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Keywords |
Animals; Anti-Bacterial Agents/*pharmacology; Cross Infection/prevention & control/*veterinary; Disease Outbreaks/prevention & control/veterinary; Drug Resistance, Bacterial; *Drug Resistance, Multiple, Bacterial; Horse Diseases/*drug therapy/transmission; Horses; Infection Control/methods; Microbial Sensitivity Tests/veterinary; Salmonella/*drug effects; Salmonella Infections, Animal/*drug therapy/transmission |
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Abstract |
Nosocomial infections are a serious threat to optimum patient care. In addition, nosocomial infections can have far-reaching consequences for the hospital personnel and the financial aspects of the hospital. Nosocomial infections with Salmonella spp have been described among hospitalized equine populations more frequently than any other agent. Salmonella spp associated with hospitalized equids often possess more antimicrobial resistance determinants than do Salmonella spp isolated from healthy horses in the general population. There is little evidence to suggest that resistant salmonellae are more virulent than nonresistant forms. MDR forms of Salmonella complicate the selection of appropriate antimicrobials when they are indicated, however. Furthermore, the use of some antimicrobials may apply selection pressure toward enhanced ability of MDR Salmonella to colonize equine patients. Further research should help to elucidate the risky uses of antimicrobials in the hospital setting and define the role of disinfectants and treatments such as NSAIDs in the ecology of MDR forms of nosocomial infections, including Salmonella. In the meantime, thoughtful selection of when and how to use antimicrobials in equine patients, together with deliberate selection of which antimicrobials to use based on monitoring data and other factors, such as safety and spectrum, is advised. |
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Address |
Animal and Plant Health Inspection Service, Veterinary Services, Centers for Epidemiology and Animal Health, United States Department of Agriculture, 2150 Centre Avenue, Building MS 2E7, Fort Collins, CO 80521, USA. david.a.dargatz@aphis.usda.gov |
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English |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0749-0739 |
ISBN |
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Expedition |
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Notes |
PMID:15519820 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2632 |
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| Permanent link to this record |
