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Author |
Owaga Ml, |
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Title |
The feeding ecology of wildbeest and zebra in Athi – Kaputei plains |
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Journal Article |
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Year |
1975 |
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Abbreviated Journal |
E Afr Wildl J |
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Volume |
13 |
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375-384 |
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Notes |
from Professor Hans Klingels Equine Reference List |
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no |
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1445 |
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Author |
Dunn, M.F.; Branlant, G. |
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Title |
Roles of zinc ion and reduced coenzyme in horse liver alcohol dehydrogenase catalysis. The mechanism of aldehyde activation |
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Journal Article |
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Year |
1975 |
Publication |
Biochemistry |
Abbreviated Journal |
Biochemistry |
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Volume |
14 |
Issue |
14 |
Pages |
3176-3182 |
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Keywords |
*Alcohol Oxidoreductases/metabolism; Aldehydes/*pharmacology; Animals; Binding Sites; Enzyme Activation/drug effects; Horses; Hydrogen-Ion Concentration; Kinetics; Liver/enzymology; *NAD/analogs & derivatives/pharmacology; Oxidation-Reduction; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Temperature; *Zinc/pharmacology |
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Abstract |
1,4,5,6-Tetrahydronicotinamide adenine dinucleotide (H2NADH) has been investigated as a reduced coenzyme analog in the reaction between trans-4-N,N-dimethylaminocinnamaldehyde (I) (lambdamax 398 nm, epsilonmax 3.15 X 10-4 M-minus 1 cm-minus 1) and the horse liver alcohol dehydrogenase-NADH complex. These equilibrium binding and temperature-jump kinetic studies establish the following. (i) Substitution of H2NADH for NADH limits reaction to the reversible formation of a new chromophoric species, lambdamax 468 nm, epsilonmax 5.8 x 10-4 M-minus 1 cm-minus 1. This chromophore is demonstrated to be structurally analogous to the transient intermediate formed during the reaction of I with the enzyme-NADH complex [Dunn, M. F., and Hutchison, J. S. (1973), Biochemistry 12, 4882]. (ii) The process of intermediate formation with the enzyme-NADH complex is independent of pH over the range 6.13-10.54. Although studies were limited to the pH range 5.98-8.72, a similar pH independence appears to hold for the H2NADH system. (iii) Within the ternary complex, I is bound within van der Waal's contact distance of the coenzyme nicotinamide ring. (iv) Formation of the transient intermediate does not involve covalent modification of coenzyme. Based on these findings, we conclude that zinc ion has a Lewis acid function in facilitating the chemical activation of the aldehyde carbonyl for reduction, and that reduced coenzyme plays a noncovalent effector role in this substrate activating step. |
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0006-2960 |
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PMID:238585 |
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Equine Behaviour @ team @ |
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3817 |
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Author |
Sivak, J.G.; Allen, D.B. |
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Title |
An evaluation of the “ramp” retina of the horse eye |
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Journal Article |
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Year |
1975 |
Publication |
Vision Research |
Abbreviated Journal |
Vision Res |
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Volume |
15 |
Issue |
12 |
Pages |
1353-1356 |
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Accommodation, Ocular; Animals; Aqueous Humor/physiology; Cornea/physiology; Freezing; Horses/*anatomy & histology; Lens, Crystalline/anatomy & histology/physiology; Refraction, Ocular; Retina/*anatomy & histology; Vitreous Body/physiology |
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Using a rapid freezing and sectioning technique, the distance between the lens and retina of the horse eye was measured. There is no indication of a ramp retina that could serve accommodation. The pupil axis of the eye coincides with the maximum lens to retina distance. The changes in the lens-retina distance are greater below the axis than above it. Calculations were made of refractive power of the horse eye from measurements of curvature and refractive indices of the ocular tissues. These calculations agree both qualitatively and quantitatively with retinoscopic measurements on live horses. Both show that the refractive state shifts in the direction of hyperopia above and below the axis and that this shift is greater below the axis than above it. Some dynamic accommodative ability in the living eye was observed. |
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0042-6989 |
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PMID:1210017 |
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no |
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Call Number |
Equine Behaviour @ team @ |
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3647 |
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Author |
Montagu I, |
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Title |
The wild ass of Africa |
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Journal Article |
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Year |
1975 |
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Abbreviated Journal |
Wild Life |
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17 |
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Pages |
400-401 |
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from Professor Hans Klingels Equine Reference List |
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no |
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1409 |
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Author |
Smuts Gl, |
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Title |
Home range sizes for Burchell's Zebra, Equus burchelli antiquorum from the Krüger National Park |
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Journal Article |
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Year |
1975 |
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Abbreviated Journal |
Koedoe |
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18 |
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Pages |
139-146 |
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Notes |
from Professor Hans Klingels Equine Reference List |
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no |
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1612 |
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Author |
Smuts Gl, |
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Title |
Pre – and postnatal growth phenomena of Burchell's Zebra, Equus Burchelli Antiquorum |
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Journal Article |
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Year |
1975 |
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Abbreviated Journal |
Koedoe |
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18 |
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69-102 |
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from Professor Hans Klingels Equine Reference List |
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no |
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1613 |
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Author |
Zentall, T.R; Hogan, D.E. |
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Title |
Key pecking in pigeons produced by pairing keylight with inaccessible grain |
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Journal Article |
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Year |
1975 |
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Abbreviated Journal |
J Exp Anal Behav |
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Volume |
23 |
Issue |
2 |
Pages |
199-206 |
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Abstract |
In Experiment I, keylight was paired with inaccessible grain delivery (under two conditions of keylight intensity) to determine if autoshaping would occur in the absence of primary reinforcement. In Experiment II, the procedure was repeated with accessible grain, for comparison. In Experiment III, the procedures were repeated with explicitly unpaired presentations of keylight and either inaccessible or accessible grain. The results indicated that key pecking occurred as quickly in the presence of keylight pairings with inaccessible grain as with accessible grain, though (except for one bird) key pecking was not maintained with inaccessible grain. Furthermore, compared to the dim keylight, the bright keylight greatly suppressed key pecking when paired with inaccessible grain, and reduced the rate of key pecking when paired with accessible grain. Little key pecking occurred in groups exposed to explicitly unpaired presentations of keylight (whether bright or dim) and grain (whether accessible or inaccessible). When the birds in Experiment III were retested with explicitly paired presentations of keylight and grain, little key pecking was observed, suggesting suppressive effects of prior explicitly unpaired presentations. It is suggested that the effects of key-brightness manipulation were produced by the association of grain with cues other than the response key, or by distraction produced by partial illumination of the grain hopper. |
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0022-5002 |
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PMID:16811840 |
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refbase @ user @ |
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273 |
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Author |
Douglas Rh, G.O. |
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Title |
Development of the equine fetus and placenta |
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Journal Article |
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Year |
1975 |
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J Reprod Fert (Suppl) |
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23 |
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495-498 |
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from Professor Hans Klingels Equine Reference List |
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no |
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1023 |
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Author |
Niekerk Van Ch, A.W. |
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Title |
Early embryonic development in the horse |
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Journal Article |
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1975 |
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J Reprod Fert Suppl |
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23 |
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495-498 |
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from Professor Hans Klingels Equine Reference List |
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no |
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1417 |
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Author |
Pickett Bw, V.J. |
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Title |
Abnormalities of mating behaviour in domestic stallions |
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1975 |
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J Reprod Fert Suppl |
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23 |
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129-134 |
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from Professor Hans Klingels Equine Reference List |
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Call Number |
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Serial |
1470 |
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