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Author |
Hostikka, S.L.; Eddy, R.L.; Byers, M.G.; Hoyhtya, M.; Shows, T.B.; Tryggvason, K. |
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Title  |
Identification of a distinct type IV collagen alpha chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome |
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Journal Article |
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Year |
1990 |
Publication |
Proceedings of the National Academy of Sciences of the United States of America |
Abbreviated Journal |
Proc. Natl. Acad. Sci. U.S.A. |
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Volume |
87 |
Issue |
4 |
Pages |
1606-1610 |
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Keywords |
Amino Acid Sequence; Base Sequence; Chromosome Mapping; Cloning, Molecular; Collagen/*genetics; Epitopes/analysis; Female; Fluorescent Antibody Technique; Gene Library; *Genes; Humans; Immunoblotting; Kidney/cytology/*metabolism; Macromolecular Substances; Molecular Sequence Data; Nephritis, Hereditary/*genetics; Oligopeptides/chemical synthesis/immunology; Placenta/metabolism; Pregnancy; Restriction Mapping; Sequence Homology, Nucleic Acid; *X Chromosome |
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We have identified and extensively characterized a type IV collagen alpha chain, referred to as alpha 5(IV). Four overlapping cDNA clones isolated contain an open reading frame for 543 amino acid residues of the carboxyl-terminal end of a collagenous domain, a 229-residue carboxyl-terminal noncollagenous domain, and 1201 base pairs coding for a 3' untranslated region. The collagenous Gly-Xaa-Yaa repeat sequence has five imperfections that coincide with those in the corresponding region of the alpha 1(IV) chain. The noncollagenous domain has 12 conserved cysteine residues and 83% and 63% sequence identity with the noncollagenous domains of the alpha 1(IV) and alpha 2(IV) chains, respectively. The alpha 5(IV) chain has less sequence identity with the putative bovine alpha 3(IV) and alpha 4(IV) chains. Antiserum against an alpha 5(IV) synthetic peptide stained a polypeptide chain of about 185 kDa by immunoblot analysis and immunolocalization of the chain in human kidney was almost completely restricted to the glomerulus. The gene was assigned to the Xq22 locus by somatic cell hybrids and in situ hybridization. This may be identical or close to the locus of the X chromosome-linked Alport syndrome that is believed to be a type IV collagen disease. |
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Biocenter, University of Oulu, Finland |
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0027-8424 |
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PMID:1689491 |
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Equine Behaviour @ team @ |
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5291 |
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Author |
Cheney D.L.; Seyfarth, R.M. |
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Title |
How monkeys see the world: Inside the mind of another species |
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1990 |
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University of Chicago Press |
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Chicago |
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refbase @ user @ |
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706 |
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Author |
Cheney, D.L.; Seyfarth, R.M. |
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Title |
How Monkeys See the World |
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Miscellaneous |
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1990 |
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Equine Behaviour @ team @ |
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4866 |
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Author |
Edgar, G.K.; Smith, A.T. |
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Title |
Hemifield differences in perceived spatial frequency |
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Journal Article |
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Year |
1990 |
Publication |
Perception |
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19 |
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6 |
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759-766 |
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Measurements of the perceived spatial frequency of stationary sinewave gratings were made with the gratings presented at the same eccentricity in the left, right, upper, and lower visual hemifields. Ten subjects performed the task binocularly with spatial frequencies of 1, 2, and 4 cycles deg-1. Two of these subjects also performed the task monocularly at 2 cycles deg-1. In the majority of cases, the spatial frequency of stimuli presented in the left and lower visual hemifields was overestimated relative to stimuli presented in the right and upper visual hemifields. The results were similar for all spatial frequencies tested, and the direction of the asymmetry was the same whether viewing was with the left eye, right eye or binocular, suggesting that the differences in perceived spatial frequency are not retinal in origin. |
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Pion Ltd |
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Equine Behaviour @ team @ |
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5374 |
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Hinrichs, K.; Watson, E.D.; Kenney, R.M. |
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Title |
Granulosa cell tumor in a mare with a functional contralateral ovary |
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Journal Article |
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Year |
1990 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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Volume |
197 |
Issue |
8 |
Pages |
1037-1038 |
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Animals; Corpus Luteum/*physiopathology; Female; Granulosa Cell Tumor/pathology/physiopathology/*veterinary; Horse Diseases/*pathology/physiopathology; Horses; Ovarian Neoplasms/pathology/*veterinary; Ovary/*pathology/physiopathology |
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A functional corpus luteum was found in the ovary contralateral to the ovary with a granulosa cell tumor in a 24-year-old Standardbred mare. The mare was ovariectomized because she was to be used as a jump mare for collection of semen from stallions. The blood concentration of progesterone was 2.2 ng/ml, and the luteal tissue progesterone concentration was 6.3 micrograms/mg. Atrophy of the contralateral ovary is one of the major signs used in diagnosis of granulosa cell tumor; however, our findings indicate that the ovary contralateral to a granulosa cell tumor is not invariably nonfunctional. |
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Department of Medicine, School of Veterinary Medicine, Tufts University, North Grafton, MA 01536 |
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0003-1488 |
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PMID:2243036 |
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Call Number |
Equine Behaviour @ team @ |
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3802 |
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Author |
Thouless, C.R. |
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Title |
Feeding competition between grazing red deer hinds |
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Journal Article |
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Year |
1990 |
Publication |
Animal Behaviour. |
Abbreviated Journal |
Anim. Behav. |
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40 |
Issue |
1 |
Pages |
105-111 |
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The effect of social rank on the feeding behaviour of female red deer, Cervus elaphus L., on the Isle of Rhum, Scotland, was investigated. Hinds were less likely to approach and more likely to leave the vicinity of other individuals if these hinds were dominant to them. Movements away by subordinates were more likely to involve a break from feeding. Feeding rate, as measured by bite rate, increased with distance from dominant neighbours, but was unaffected by the distance to subordinates. It appears that aggressive interactions had little direct effect on access to food. Instead, it is suggested that feeding competition in red deer hinds is largely a passive process, operating through the avoidance of conflict by subordinates. |
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Equine Behaviour @ team @ |
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4267 |
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Author |
Thierry, B. |
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Title |
Feedback loop between kinship and dominance: the macaque model |
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Journal Article |
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Year |
1990 |
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Journal of Theoretical Biology |
Abbreviated Journal |
J. Theor. Biol. |
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145 |
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4 |
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511-522 |
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There is growing evidence that macaque social systems represent sets of coadapted traits in which strength of hierarchies and degree of nepotism covary. A framework is developed to explain the link between dominance and kinship phenomena, assuming that power brought by alliances among non-kin is allometrically related to those involving relatives. This can account for the type of social relationships observed in “despotic” systems vs. “egalitarian” ones. When social bonds are mostly founded on kinship, lineages are closed and social power generated by coalitions among relatives may reach high levels; social power frequently outweighs the fighting abilities of single individuals, and asymmetry of dominance between group members may be marked. When lineages are more open, social bonds and alliances are less kin-biased, social relationships are more equal, and as the influence of coalitions is less important, the individual retains a certain degree of freedom in relation to the power of kin-networks. Acknowledging that the balance between individual and social power is not set at the same level across different species can explain a number of variations in rules of rank inheritance and relative dominance of males and females among macaques. The framework illustrates how epigenetic processes may shape complex features of primate social systems, and offers opportunities for testing. |
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refbase @ user @ |
Serial |
867 |
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Author |
Huizinga, H.A.; Boukamp, M.; Smolders, G. |
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Estimated parameters of field performance testing of mares from the Dutch Warmblood riding horse population |
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Journal Article |
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Year |
1990 |
Publication |
Livestock Production Science |
Abbreviated Journal |
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26 |
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4 |
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291-299 |
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competition; genetic parameters; horse breeding; mares; performance test |
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The field performance testing (FPT) of mares of the Dutch Warmblood riding horse population is evaluated. Phenotypic and genetic parameters of scored traits are estimated and the genetic relationship with performance of half-sibs in dressage and jumping competition are estimated. Data from 1984 to 1987 are used, covering scores from 2023 at least 3-year-old mares. Seven subjectively scored traits are considered, walk, trot, canter, riding ability, character, jumping ability and total score. Analysis of data is according to a sire model. Variance and covariance components are estimated by Restricted Maximum Likelihood (REML) procedures. Estimates of heritability are moderately low for gaits (average 0.19), jumping ability (0.15) and total score (0.17) and extremely low for riding ability (0.03) and character (0.06). Dressage in competition is most correlated with riding ability (0.83) and is moderately correlated with total score (0.41) from FPT of mares. Jumping competition is most correlated with jumping ability (0.48) and not correlated with total score (0.05) from field test of mares. Some possible bias owing to previous knowledge and preselection is discussed. It is concluded that efficiency of present FPT of mares is limited for selection of broodmares for dressage and jumping ability in competition. |
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refbase @ user @ |
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3964 |
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Loyola, E.G.; Rodriguez, M.H.; Gonzalez, L.; Arredondo, J.I.; Bown, D.N.; Vaca, M.A. |
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Title |
Effect of indoor residual spraying of DDT and bendiocarb on the feeding patterns of Anopheles pseudopunctipennis in Mexico |
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Journal Article |
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Year |
1990 |
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Journal of the American Mosquito Control Association |
Abbreviated Journal |
J Am Mosq Control Assoc |
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6 |
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4 |
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635-640 |
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Animals; Anopheles/*physiology; *Carbamates; Cattle; *Ddt; Ecology; Enzyme-Linked Immunosorbent Assay; Feeding Behavior/*drug effects; Horses; Humans; Insect Vectors; Insecticide Resistance; *Insecticides; Mexico; *Phenylcarbamates; Seasons |
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Intense and persistent use of DDT for malaria control has increased resistance and induced exophilic behavior of Anopheles pseudopunctipennis. An evaluation of bendiocarb and DDT to control this species in Sinaloa, Mexico, showed that, in spite of DDT-resistance, both insecticides produced similar effects. Feeding patterns were analyzed to explain these results. Resting mosquitoes were collected over the dry and wet seasons. Anophelines were tested in an ELISA to determine the source of the meals. The human blood index (HBI) ranged from 3.3 to 6.8% in DDT- and from 12.7 to 26.9% in bendiocarb-sprayed houses. Irritability and repellency in DDT-sprayed houses could explain the reduced HBI. In contrast, bendiocarb produced higher mortality. These effects could have affected different components of the vectorial capacity and similarly reduced malaria. |
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Center for Malaria Research, Chiapas, Mexico |
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8756-971X |
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PMID:2098469 |
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Equine Behaviour @ team @ |
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2671 |
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Author |
Janson, C.H. |
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Ecological consequences of individual spatial choice in foraging groups of brown capuchin monkeys, Cebus apella |
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Year |
1990 |
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Animal Behaviour. |
Abbreviated Journal |
Anim. Behav. |
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40 |
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5 |
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922-934 |
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Individuals in a foraging group of brown capuchin monkeys choose different spatial positions relative to the rest of the group. An individual's choice of spatial positiion affects its foraging success and perceived predation risk (as measured by vigilance behaviour). The two most dominant group members preferred to forage where their expected forwaging success was greatest. Juveniles chose to forage where their perceived predation risk was least, not where they would achieve the highest foraging success. The positions used by non-dominant adults neither maximized foraging success nor minimized predation risk. It is likely that subordinate adults accept spatial positions with suboptimal ecological consequences to avoid the costs of frequent confrontations with the dominant members of the group over foraging sites in poreferred positions. |
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refbase @ user @ |
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774 |
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