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Ecker, C.; Marquand, A.; Mourao-Miranda, J.; Johnston, P.; Daly, E.M.; Brammer, M.J.; Maltezos, S.; Murphy, C.M.; Robertson, D.; Williams, S.C.; Murphy, D.G.M. |
![goto web page (via DOI) doi](img/doi.gif)
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Describing the Brain in Autism in Five Dimensions--Magnetic Resonance Imaging-Assisted Diagnosis of Autism Spectrum Disorder Using a Multiparameter Classification Approach |
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2010 |
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J. Neurosci. |
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J. Neurosci. |
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30 |
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32 |
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10612-10623 |
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Autism spectrum disorder (ASD) is a neurodevelopmental condition with multiple causes, comorbid conditions, and a wide range in the type and severity of symptoms expressed by different individuals. This makes the neuroanatomy of autism inherently difficult to describe. Here, we demonstrate how a multiparameter classification approach can be used to characterize the complex and subtle structural pattern of gray matter anatomy implicated in adults with ASD, and to reveal spatially distributed patterns of discriminating regions for a variety of parameters describing brain anatomy. A set of five morphological parameters including volumetric and geometric features at each spatial location on the cortical surface was used to discriminate between people with ASD and controls using a support vector machine (SVM) analytic approach, and to find a spatially distributed pattern of regions with maximal classification weights. On the basis of these patterns, SVM was able to identify individuals with ASD at a sensitivity and specificity of up to 90% and 80%, respectively. However, the ability of individual cortical features to discriminate between groups was highly variable, and the discriminating patterns of regions varied across parameters. The classification was specific to ASD rather than neurodevelopmental conditions in general (e.g., attention deficit hyperactivity disorder). Our results confirm the hypothesis that the neuroanatomy of autism is truly multidimensional, and affects multiple and most likely independent cortical features. The spatial patterns detected using SVM may help further exploration of the specific genetic and neuropathological underpinnings of ASD, and provide new insights into the most likely multifactorial etiology of the condition. |
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10.1523/Jneurosci.5413-09.2010 |
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Equine Behaviour @ team @ |
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5191 |
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Fiske, J.C.; Potter, G.D. |
![goto web page (via DOI) doi](img/doi.gif)
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Title |
Discrimination reversal learning in yearling horses |
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1979 |
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J. Anim. Sci. |
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J. Anim. Sci. |
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49 |
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2 |
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583-588 |
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Twenty-six yearling horses were tested on a serial reversal learning discrimination combining spatial and brightness cues. An original discrimination of rewarded or nonrewarded stimuli was made followed by 20 daily reversals for position/brightness discrimination. Learning criteria were defined as 11 out of 12 correct, with the last eight responses all correct. Each horse was allowed 30 trials per discrimination to achieve criteria. Mean errors (ME) and mean trials (MT) required to achieve criteria were computed for each horse. A relative learning ability index (LAI) was calculated by the formula 1000/MT/ME. A daily emotionality score, based on a scale of one (tranquil) to six (very excitable) was assigned each horse each day after testing and a mean computed for each horse. A single subjective trainability score, based on a scale of one (difficult to train) to six (easy to train) was obtained for each horse from an independent trainer. Linear regression analyses for all 26 horses revealed a reduction in MT and ME (P<.01) over the 21-day test period indicating evidence of learning to learn. Differences (P<.05) were evident between sexes for MT and ME. Significant correlations between trainability scores and learning ability indices MT, ME, and LAI were evident for colts and geldings but not for fillies. Pooled data showed significant correlations between ME and trainability. There was a negative correlation (P<.05) between emotionality and trainability scores for all 26 horses, although the filly group did not exhibit significant correlation between these parameters. |
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Cited By (since 1996): 31; Export Date: 24 October 2008 |
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Admin @ knut @ |
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4583 |
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McCall, C.A.; Potter, G.D.; Friend, T.H.; Ingram, R.S. |
![find record details (via OpenURL) openurl](img/xref.gif)
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Learning abilities in yearling horses using the Hebb-Williams closed field maze |
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1981 |
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J. Anim. Sci. |
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J. Anim. Sci. |
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53 |
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4 |
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928-933 |
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Cited By (since 1996): 9; Export Date: 24 October 2008 |
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Admin @ knut @ |
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4613 |
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Herbst, C.T.; Herzel, H.; Svec, J.G.; Wyman, M.T.; Fitch, W.T. |
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Visualization of system dynamics using phasegrams |
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2013 |
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J R Soc Interface |
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10 |
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Equine Behaviour @ team @ Herbst2013 |
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6487 |
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Riede, T.; Herzel, H.; Mehwald, D.; Seidner, W.; Trumler, E.; Böhme, G. |
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Nonlinear phenomena in the natural howling of a dog-wolf mix |
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2000 |
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J Acoust Soc Am |
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108 |
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Equine Behaviour @ team @ Riede2000 |
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6484 |
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Bannikov, A.G. |
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Recent status of the wild ass in Mongolia |
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1975 |
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IUCN Bulletin |
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6 |
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4 |
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16 |
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Equine Behaviour @ team @ |
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2219 |
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Clark, T.B.; Peterson, B.V.; Whitcomb, R.F.; Henegar, R.B.; Hackett, K.J.; Tully, J.G. |
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Spiroplasmas in the Tabanidae |
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1984 |
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Israel Journal of Medical Sciences |
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Isr J Med Sci |
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20 |
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10 |
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1002-1005 |
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Animals; Diptera/*microbiology/ultrastructure; Ecology; Female; Hemolymph/microbiology; Male; Maryland; North Carolina; Plants/microbiology; Spiroplasma/classification/*isolation & purification/physiology |
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Spiroplasmas were observed in seven species of the family Tabanidae (horse flies and deer flies). This is the fifth family of the order Diptera now known to harbor spiroplasmas. Noncultivable spiroplasmas were seen in the hemolymph of three species of the genus Tabanus, and cultivable forms were isolated from the guts of six species in three genera. Isolates from T. calens and T. sulcifrons were serologically similar and closely related to a spiroplasma in the lampyrid beetle, Ellychnia corrusca. These three isolates represent a new serogroup. Isolates from Hybomitra lasiophthalma were related to Group IV strains, while those from T. nigrovittatus and Chrysops sp. both represented new serogroups. At least some tabanids probably acquire spiroplasmas from contaminated flower surfaces. The possibility of vertebrate reservoirs for some tabanid spiroplasmas remains an open question. |
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English |
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0021-2180 |
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PMID:6511308 |
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Equine Behaviour @ team @ |
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2687 |
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Kaplan, G.; Rogers, L.J. |
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Title |
Patterns of Gazing in Orangutans (Pongo pygmaeus) |
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2002 |
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International Journal of Primatology |
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Int. J. Primatol. |
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23 |
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3 |
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501-526 |
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Eyes play an important role in communication amongst humans and animals. However, relatively little is known about specific differences in eye morphology amongst primates and how these features might be associated with social structure and direction of gaze. We present a detailed study of gazing and eye morphology-exposed sclera and surrounding features in orangutans. We measured gazing in rehabilitating orangutans in two contexts: interspecific viewing of the experimenter (with video camera) and intraspecific gazing (between subjects). Our findings show that direct staring is avoided and social looking is limited to certain age/social categories: juveniles engage in more looking at other orangutans than do adults or infants. While orangutans use eye movements in social communication, they avoid the more prolonged mutual gaze that is characteristic of humans, and also apparent in chimpanzees and gorillas. Detailed frame-by-frame analysis of videotapes from field and zoo studies of orangutans revealed that they pay visual attention to both human observers and conspecifics by glancing sideways, with the head turned at an angle away from the subject being observed. Mutual gaze was extremely rare, and we have observed only two incidences of gaze following. Orangutans in captivity appear to use a more restricted pattern of gazes compared to free-living, rehabilitating ones, possibly suggesting the presence of a pathological condition (such as depression) in the captive subjects. Our findings have implications for further investigations of social communication and cognition in orangutans. |
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Equine Behaviour @ team @ |
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3398 |
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Visser, E. K.; Ellis, A.D.; Rijksen, L.; Van Reenen,C.G.; VanDierendonck,M. |
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Title |
Effect of training method on response of horses to a human approach test |
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2008 |
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IESM 2008 |
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Horse, training, welfare |
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The human-horse relationship forms an essential component in the diversity of todays use of horses. The reactions of horses to interactions with humans are mostly the result of interplay between their own temperament; the temperament and skills of the human and their previous experience – with humans. Moreover, the understanding of the human-horse relationship may improve the welfare of horses and humans. Nowadays, “sympathetic” training methods are gaining tremendous attention of horse owners. In the “sympathetic” training method the focus lies on the use of body language in human-horse communication, as well as respecting the horses natural needs. With 28 horses the effect of a “sympathetic” training method versus a conventional training method on the horse“s response on a human-approach test was studied. Fourteen horses of 3.5 years of age were subjected to a five week training period with a conventional training method, the other fourteen horses were subjected to a ”sympathetic“ training method. The overall frequency of snorting during the human approach tests decreased on average from 4.4 (± 1.1) before the training period to 3.1 (± 0.9) after the training period (both groups). However, there was a significant (p=0.006) difference between training methods: the horses trained in the ”sympathetic“ method decreased snorting by 4.3 (±1.1) while the horses trained in the conventional method increased with 1.5 (±0.9). While horses trained in the conventional method whinnied less in the second human approach test, horses trained in the ”sympathetic“ method whinnied more after the period of training. This difference was found to be significant (p=0.006). Defecating decreased over time, but was not different between training methods. The frequency of touching the unfamiliar handler increased over time for both training methods. The horses trained in a conventional method increased from 1.5 to 2.5 and for the sympathetic trained horses from 1.9 to 3.7. This increase was not significantly different for the training methods. Heart rate showed a minor decrease between the human approach tests (before training period 85.3 bpm, after training period 74.3 bpm) but there were no significant differences between training methods. Similarly, there was a slight increase in heart rate variability (rmssd: from 37.0 to 45.2), but no significant differences between training methods. Overal it was concluded that horses trained with this ”sympathetic“ method tended to be more trustful and less stressful in the presence of an (unfamiliar) human compared to horses trained with a conventional method. This may have been due to reduced stress during horse-human contact in the ”sympathetic" training method used. The long term effects on the welfare of the horses, still needs to be investigated. |
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Animal Sciences Group, Wageningen University and Research Centres, PO Box 65, 8200 AB Lelystad |
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Visser, E. K. |
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IESM 2008 |
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Poster IESM 2008 |
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yes |
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Equine Behaviour @ team @ |
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4468 |
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De Pasquale, A.; Ingala, A.; Innella, G.; Luigiano, G.; Malara, L.; Panzera, M. |
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Title |
The influence of the enriched environment on the reactivity of the precociously handled foals (Equus caballus L.). |
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2008 |
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IESM 2008 |
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Foal, Handling, Enriched environment, Reactivity. |
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In a preliminary study, we evaluated the effect of precocious handling (at birth, 10, 30 and 60 days) and enriched environment on foal. Two experimental groups were created:
- 3 foals not handled and stabled in semi-enriched environment (Group A).
- 6 foals handled and stabled in an enriched environment (Group B).
All nine foals were tested with a novel object test (umbrella) at three months of age, to assess the Heart Rate (HR) values measured by a telemetric heart rate monitor (Polar Horse Trainer), during opening, touching and closing of the umbrella.
The statistical analysis carried out by means of the Mann-Whitney test showed lower HR values of the foals of group B (P<0.05).
Furthermore we have investigated 10 foals born between 2006 and 2008 to study the influence of enriched environment and precocious handling on behavioural responsiveness. The foals were housed on a farm which ensured an enriched environment and made social intra and interspecific interactions easier, alias autoshaping. They were submitted to:
- Handling within 24 hours from birth.
- Handling and reactivity test (arena test) executed at 10, 30 and 60 days.
The temporal correlation was studied among ages and baseline HR values, using the
Spearman"s test, to assess the beginning of neurovegetative HR control.
In fact statistically significant differences were obtained (r = -0.431; P<0,02). Temporal values of obtained HR baseline, using the Wilcoxon test, showed lower values at 60 days. The comparison was significant among mean and max baseline HR values of 30 vs 60 and 10 vs 60 (P<0.05), while no differences were observed during the reactivity test. This shows that adequate conditions of management associated to a precocious and continuous handling allow the foals to maintain their natural investigative behaviour disappearing fear and flight reactions. |
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Dept. of Experimental Sciences and Applied Biotechnologies, Unit of Applied Physiology and Comparative Ethology , Faculty of Veterinary Medicine – University of Messina, Italy. |
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De Pasquale, A |
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IESM 2008 |
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Talk 15 min IESM 2008 |
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yes |
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Equine Behaviour @ team @ |
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4486 |
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