| |
Records |
Links |
|
Author |
Andersson, P.; Kvassman, J.; Lindstrom, A.; Olden, B.; Pettersson, G. |
|
| |
Title |
Effect of NADH on the pKa of zinc-bound water in liver alcohol dehydrogenase |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
European Journal of Biochemistry / FEBS |
Abbreviated Journal |
Eur J Biochem |
|
| |
Volume |
113 |
Issue |
3 |
Pages |
425-433 |
|
| |
Keywords |
Alcohol Oxidoreductases/*metabolism; Aldehydes/metabolism; Animals; Binding Sites; Cinnamates/metabolism; Horses; Hydrogen-Ion Concentration; Kinetics; Ligands; Liver/*metabolism; NAD/*metabolism; Water/metabolism; Zinc/metabolism |
|
| |
Abstract |
Equilibrium constants for coenzyme binding to liver alcohol dehydrogenase have been determined over the pH range 10--12 by pH-jump stop-flow techniques. The binding of NADH or NAD+ requires the protonated form of an ionizing group (distinct from zinc-bound water) with a pKa of 10.4. Complex formation with NADH exhibits an additional dependence on the protonation state of an ionizing group with a pKa of 11.2. The binding of trans-N,N-dimethylaminocinnamaldehyde to the enzyme . NADH complex is prevented by ionization of the latter group. It is concluded from these results that the pKa-11.2-dependence of NADH binding most likely derives from ionization of the water molecule bound at the catalytic zinc ion of the enzyme subunit. The pKa value of 11.2 thus assigned to zinc-bound water in the enzyme . NADH complex appears to be typical for an aquo ligand in the inner-sphere ligand field provided by the zinc-binding amino acid residues in liver alcohol dehydrogenase. This means that the pKa of metal-bound water in zinc-containing enzymes can be assumed to correlate primarily with the number of negatively charged protein ligands coordinated by the active-site zinc ion. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0014-2956 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes  |
PMID:7011796 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
3810 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Bernstein, I.S.; Dobrofsky, M. |
|
| |
Title |
Compensatory social responses of older pigtailed monkeys to maternal separation |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
Developmental Psychobiology |
Abbreviated Journal |
Dev Psychobiol |
|
| |
Volume |
14 |
Issue |
2 |
Pages |
163-168 |
|
| |
Keywords |
Animals; Dependency (Psychology); Female; Macaca nemestrina; Male; *Maternal Deprivation; *Social Behavior |
|
| |
Abstract |
Thirteen 3-5-year-old pigtailed monkeys were subjected to five 2-hr maternal separations while remaining in their normal social group. Significant changes in activity profiles were noted during separation and reunion phases. This suggests the continued social dependence of older offspring upon the matriarch. The shift in social activities reflected attempts by the juvenile and adolescent subjects to compensate for maternal absence by intensification of other affiliative social behavior and avoidance of potentially socially disruptive situation. The subjects oriented more towards kin in the absence of the matriarch, but actual time with kin decreased. Upon the return of the matriarch, the intensified some responses depressed during her absence and returned to preseparation social relationships. Play and aggressive responses declined whereas social approaches increased during maternal absences. Submissive responses declined upon the return of the matriarch, and play increased. The subjects also showed a marked, temporary increase of direct interaction, largely sniffing and grooming, with the matriarch upon her return. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0012-1630 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:7202854 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
4171 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Hendricks, J.C.; Morrison, A.R. |
|
| |
Title |
Normal and abnormal sleep in mammals |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
|
| |
Volume |
178 |
Issue |
2 |
Pages |
121-126 |
|
| |
Keywords |
Animals; Cat Diseases/physiopathology; Cats; Cattle; Dog Diseases/physiopathology; Dogs; Dreams; Horses/physiology; Humans; Narcolepsy/physiopathology/veterinary; Sleep/*physiology; Sleep Apnea Syndromes/physiopathology/veterinary; Sleep Disorders/physiopathology/*veterinary; Sleep, REM/physiology |
|
| |
Abstract |
|
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0003-1488 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:7204232 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
101 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Hoff, M.P.; Nadler, R.D.; Maple, T.L. |
|
| |
Title |
Development of infant independence in a captive group of lowland gorillas |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
Developmental Psychobiology |
Abbreviated Journal |
Dev Psychobiol |
|
| |
Volume |
14 |
Issue |
3 |
Pages |
251-265 |
|
| |
Keywords |
Animals; *Dependency (Psychology); Female; Gorilla gorilla/*growth & development; Male; Maternal Behavior; *Personality; Sex Factors; Social Behavior; Weaning |
|
| |
Abstract |
In March 1976, 3 lowlands gorillas (Gorilla gorilla gorilla) were born to primiparous females living with an adult male in a large compound at the field station of the Yerkes Regional Primate Research Center of Emory University. Observations of parent and infant behavior began at the birth of the infants, using several methods of data collection. This report focuses on the development of independence in these infants over the 1st 1 1/2 years of life. As expected, measures of mother-infant contact and proximity decreased with age. Several measures suggested that infant independence developed as an interactive process between mothers and infants, with primary responsibility changing over the months of study. Maternal behaviors that served to maintain mother-infant contact were found to decrease with age, with an eventual shift to infant responsibility for contact maintenance. Additionally, the adult male appeared to influence developing independence as reflected in the maternal protectiveness evoked by his behavior. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0012-1630 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:7262467 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
4170 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Cambefort, J.P. |
|
| |
Title |
A comparative study of culturally transmitted patterns of feeding habits in the chacma baboon Papio ursinus and the vervet monkey Cercopithecus aethiops |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
Folia Primatologica; International Journal of Primatology |
Abbreviated Journal |
Folia Primatol (Basel) |
|
| |
Volume |
36 |
Issue |
3-4 |
Pages |
243-263 |
|
| |
Keywords |
Age Factors; Animals; *Cercopithecus; *Cercopithecus aethiops; Culture; *Feeding Behavior; Female; Group Structure; Learning; Male; *Papio; Social Class; Teaching |
|
| |
Abstract |
Japanese workers have studied social acquisition patterns of new feeding habits in Macaca fuscata which they have termed precultural. The present study investigates the same phenomenon in the chacma baboon and the vervet monkey in their natural habitat. The questions addressed are: (1) How a new feeding habit enters a troop and by which age and sex category, also how it is propagated? (2) When individuals are permitted with a choice between palatable and unpalatable food, can they learn by demonstration only or do they have to pass through a direct learning process? (3) Can the results from the above questions be explained by social parameters such as the social structure of the individual species? It was found that juvenile baboons discover new food and that after the discovery propagation is instantaneous. In vervets discovery is random among the age classes and propagation is slow and takes place through certain 'pivot' individuals. Both species fail to learn about palatability by demonstration but have to go through a direct learning process. This contrasts strongly with the forest baboon Mandrillus sphinx that have been shown to learn by demonstration. Socially, baboon juveniles stay closer to each other than the adults who force them to live at the periphery of the troop. Vervets again forage without precise sub-group formation. The link between social and cultural propagation and social structure is discussed on the basis of these findings. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0015-5713 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:7319426 |
Approved |
no |
|
| |
Call Number |
|
Serial |
2087 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Heird, J.C.; Lennon, A.M.; Bell, R.W. |
|
| |
Title |
Effects of early experience on the learning ability of yearling horses |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
Journal of Animal Science |
Abbreviated Journal |
J. Anim Sci. |
|
| |
Volume |
53 |
Issue |
5 |
Pages |
1204-1209 |
|
| |
Keywords |
Animals; Conditioning (Psychology); Female; *Handling (Psychology); Horses/*physiology; *Learning |
|
| |
Abstract |
Twenty-four yearling Quarter Horse fillies were divided into three groups (I) very limited handling, (II) intermediate handling and (III) extensive handling. At about 14 months of age, each horse was preconditioned for 2 weeks and then run in a simple place-learning T-maze test in which it had to locate its feed. Thirty trials were run daily for 20 days, with the location of the feed changed each day. To retire from the maze, a horse had to meet the criterion: 11 correct responses in 12 tries, with the last eight being consecutive. Horses in Group II required the fewest trials to reach criterion. These horses also learned more and had the highest percentage of correct responses (P less than .05). Mean trainability tended to predict learning ability; however, trainability and trials to criterion were not significantly correlated. Mean emotionality scores indicated a tendency for horses in the intermediately handled group to be less emotional than those in Group I or III. Results indicated that horses with an intermediate amount of handling scored higher on an intermediate test of learning. All handled horses scored higher on learning tests than those not handled. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0021-8812 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:7319966 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
3577 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Boice, R. |
|
| |
Title |
Behavioral comparability of wild and domesticated rats |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
|
| |
Volume |
11 |
Issue |
5 |
Pages |
545-553 |
|
| |
Keywords |
Animals; *Behavior, Animal; Female; Genetics, Behavioral; Intelligence; Learning; Male; Rats/*genetics |
|
| |
Abstract |
The oft-repeated concern for the lack of behavioral comparability of domestic rats with wild forms of Rattus norvegicus is unfounded. Laboratory rats appear to show the potential for all wild-type behaviors, including the most dramatic social postures. Moreover, domestics are capable of assuming a feral existence without difficulty, one where they readily behave in a fashion indistinguishable from wild rats. The one behavioral difference that is clearly established concerns performance in laboratory learning paradigms. The superiority of domestics in these laboratory tasks speaks more to quieting the concerns of degeneracy theorists than to problems of using domestic Norway rats as subjects representative of their species. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0001-8244 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:7325955 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
4144 |
|
| Permanent link to this record |
