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Author |
Czerlinski, G.H.; Erickson, J.O.; Theorell, H. |
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Title |
Chemical relaxation studies on the horse liver alcohol dehydrogenase system |
Type |
Journal Article |
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Year |
1979 |
Publication |
Physiological Chemistry and Physics |
Abbreviated Journal |
Physiol Chem Phys |
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Volume |
11 |
Issue |
6 |
Pages |
537-569 |
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Keywords |
Alcohol Oxidoreductases/*metabolism; Animals; Buffers; Electron Transport; Ethanol/metabolism; Horses; Hydrogen-Ion Concentration; Liver/*enzymology; Mathematics; NAD/metabolism; Oscillometry; Osmolar Concentration; Temperature; Time Factors |
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Abstract |
Chemical relaxation studies on the system horse liver alcohol dehydrogenase, nicotinamide adenine dinucleotide, and ethanol were conducted observing fluorescence changes between 400 and 500 nm. Temperature-jump experiments were performed at pH 6.5, 7.0, 8.0, and 9.0; concentration-jump experiments at pH 9.0. The reciprocal of the slowest relaxation time was found to be linearly dependent upon the enzyme concentration for relatively low enzyme concentrations, as predicted earlier. Use of the wide pH-range necessitated expression of the four apparent dissociation constants of the catalytic reaction cycle in terms of pH-independent constants. The system was described in terms of only one (or two) catalysis-linked protons not associated with the electron transfer. Protonic steps in a buffered system are in rapid equilibrium, too fast to be measured with the equipment available. Assuming only two of the four bimolecular reaction steps in the four-step cycle are fast compared to the remaining two, six cases may be considered with six expressions for the reciprocal of the slowest relaxation time. Comparison with the experimental data revealed that the bimolecular reaction steps governing the slowest relaxation time change with pH. Above the effective time resolution of the temperature-lump instrument with fluorescence detection (0.1 msec) only one other relaxation time was detectable and only at pH 9. This relaxation time, found to be independent of the concentration of all reactants within experimental error (r = 10 +/- 5 msec), is most likely due to an interconversion among ternary complexes. |
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0031-9325 |
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PMID:44918 |
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Equine Behaviour @ team @ |
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3813 |
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Author |
Ogbourne, C.P. |
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Title |
Variations in the fecundity of strongylid worms of the horse |
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Journal Article |
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Year |
1971 |
Publication |
Parasitology |
Abbreviated Journal |
Parasitology |
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Volume |
63 |
Issue |
2 |
Pages |
289-298 |
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Keywords |
Animals; Animals, Newborn; Ecology; Feces; Female; Horses; Larva/growth & development; Male; Ovum; Parasite Egg Count; Reproduction; Seasons; Strongyle Infections, Equine/*etiology; Strongyloides/*growth & development; Time Factors |
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0031-1820 |
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PMID:5129804 |
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Call Number |
Equine Behaviour @ team @ |
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2727 |
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Author |
Houpt, T.R. |
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Title |
The physiological determination of meal size in pigs |
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Journal Article |
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Year |
1985 |
Publication |
The Proceedings of the Nutrition Society |
Abbreviated Journal |
Proc Nutr Soc |
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Volume |
44 |
Issue |
2 |
Pages |
323-330 |
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Keywords |
Animals; Appetite/physiology; Drinking; Duodenum/physiology; *Eating; Energy Intake; Food; Horses/physiology; Milk; Osmolar Concentration; Receptors, Cell Surface/physiology; Receptors, Cholecystokinin; Swine/*physiology; Time Factors |
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0029-6651 |
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PMID:2996010 |
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no |
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Call Number |
refbase @ user @ |
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53 |
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Author |
Moses, S.N.; Villate, C.; Ryan, J.D. |
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Title |
An investigation of learning strategy supporting transitive inference performance in humans compared to other species |
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Journal Article |
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Year |
2006 |
Publication |
Neuropsychologia |
Abbreviated Journal |
Neuropsychologia |
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Volume |
44 |
Issue |
8 |
Pages |
1370-1387 |
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Keywords |
Adult; Analysis of Variance; Association Learning/*physiology; *Cognition; *Concept Formation; Female; Humans; *Logic; Male; Pattern Recognition, Visual/physiology; Photic Stimulation/methods; Reaction Time/physiology |
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Abstract |
Generalizations about neural function are often drawn from non-human animal models to human cognition, however, the assumption of cross-species conservation may sometimes be invalid. Humans may use different strategies mediated by alternative structures, or similar structures may operate differently within the context of the human brain. The transitive inference problem, considered a hallmark of logical reasoning, can be solved by non-human species via associative learning rather than logic. We tested whether humans use similar strategies to other species for transitive inference. Results are crucial for evaluating the validity of widely accepted assumptions of similar neural substrates underlying performance in humans and other animals. Here we show that successful transitive inference in humans is unrelated to use of associative learning strategies and is associated with ability to report the hierarchical relationship among stimuli. Our work stipulates that cross-species generalizations must be interpreted cautiously, since performance on the same task may be mediated by different strategies and/or neural systems. |
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Address |
Rotman Research Institute, Baycrest Centre for Geriatric Care, Toronto, Canada. smoses@rotman-baycrest.on.ca |
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0028-3932 |
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PMID:16503340 |
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no |
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Call Number |
refbase @ user @ |
Serial |
153 |
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Author |
de Waal, F.B.M.; Davis, J.M. |
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Title |
Capuchin cognitive ecology: cooperation based on projected returns |
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Journal Article |
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Year |
2003 |
Publication |
Neuropsychologia |
Abbreviated Journal |
Neuropsychologia |
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Volume |
41 |
Issue |
2 |
Pages |
221-228 |
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Keywords |
Animals; Attention; Cebus/*psychology; *Cooperative Behavior; Decision Making; Dominance-Subordination; Female; Male; *Motivation; Reaction Time; Reinforcement Schedule; *Social Behavior |
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Abstract |
Stable cooperation requires that each party's pay-offs exceed those available through individual action. The present experimental study on brown capuchin monkeys (Cebus apella) investigated if decisions about cooperation are (a) guided by the amount of competition expected to follow the cooperation, and (b) made instantaneously or only after a period of familiarization. Pairs of adult monkeys were presented with a mutualistic cooperative task with variable opportunities for resource monopolization (clumped versus dispersed rewards), and partner relationships (kin versus nonkin). After pre-training, each pair of monkeys (N=11) was subjected to six tests, consisting of 15 2 min trials each, with rewards available to both parties. Clumped reward distribution had an immediate negative effect on cooperation: this effect was visible right from the start, and remained visible even if clumped trials alternated with dispersed trials. The drop in cooperation was far more dramatic for nonkin than kin, which was explained by the tendency of dominant nonkin to claim more than half of the rewards under the clumped condition. The immediacy of responses suggests a decision-making process based on predicted outcome of cooperation. Decisions about cooperation thus take into account both the opportunity for and the likelihood of subsequent competition over the spoils. |
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Living Links, Yerkes Primate Center, Emory University, 954 N. Gatewood Road, Atlanta, GA 30322, USA. dewaal@emory.edu |
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0028-3932 |
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Notes |
PMID:12459220 |
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no |
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Call Number |
refbase @ user @ |
Serial |
182 |
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Author |
Rands, S.A.; Cowlishaw, G.; Pettifor, R.A.; Rowcliffe, J.M.; Johnstone, R.A. |
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Title |
Spontaneous emergence of leaders and followers in foraging pairs |
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Journal Article |
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Year |
2003 |
Publication |
Nature |
Abbreviated Journal |
Nature |
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Volume |
423 |
Issue |
6938 |
Pages |
432-434 |
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Keywords |
Animals; *Energy Metabolism; Food; *Food Chain; *Models, Biological; Motor Activity; *Social Behavior; Time Factors |
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Abstract |
Animals that forage socially often stand to gain from coordination of their behaviour. Yet it is not known how group members reach a consensus on the timing of foraging bouts. Here we demonstrate a simple process by which this may occur. We develop a state-dependent, dynamic game model of foraging by a pair of animals, in which each individual chooses between resting or foraging during a series of consecutive periods, so as to maximize its own individual chances of survival. We find that, if there is an advantage to foraging together, the equilibrium behaviour of both individuals becomes highly synchronized. As a result of this synchronization, differences in the energetic reserves of the two players spontaneously develop, leading them to adopt different behavioural roles. The individual with lower reserves emerges as the 'pace-maker' who determines when the pair should forage, providing a straightforward resolution to the problem of group coordination. Moreover, the strategy that gives rise to this behaviour can be implemented by a simple 'rule of thumb' that requires no detailed knowledge of the state of other individuals. |
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Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK. s.rands@zoo.cam.ac.uk |
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ISSN |
0028-0836 |
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Notes |
PMID:12761547 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
5138 |
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Author |
Seyfarth, R.M. |
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Title |
A model of social grooming among adult female monkeys |
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Journal Article |
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Year |
1977 |
Publication |
Journal of Theoretical Biology |
Abbreviated Journal |
J. Theor. Biol. |
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Volume |
65 |
Issue |
4 |
Pages |
671-698 |
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Keywords |
Animals; Behavior, Animal; Female; *Grooming; Haplorhini/*physiology; *Models, Biological; Reproduction; Social Dominance; Time Factors |
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Abstract |
Grooming networks among adult female monkeys exhibit two similar features across a number of different species. High-ranking animals receive more grooming than others, and the majority of grooming occurs between females of adjacent rank. A theoretical model which duplicates these features is presented, and the properties of the model are used to explain the possible causation and function of female grooming behaviour. The model illustrates how relatively simple principles governing the behaviour of individuals may be used to explain more complex aspects of the social structure of non-human primate groups. |
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0022-5193 |
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PMID:406485 |
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Equine Behaviour @ team @ |
Serial |
5259 |
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Author |
Zentall, T.R. |
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Title |
Support for a theory of memory for event duration must distinguish between test-trial ambiguity and actual memory loss |
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Journal Article |
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Year |
1999 |
Publication |
Journal of the experimental analysis of behavior |
Abbreviated Journal |
J Exp Anal Behav |
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Volume |
72 |
Issue |
3 |
Pages |
467-472 |
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Keywords |
Animals; Behavior, Animal/physiology; Columbidae; Conditioning, Operant/physiology; Discrimination Learning/physiology; Memory/*physiology; *Psychological Theory; Time Factors; Time Perception/physiology |
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Abstract |
Staddon and Higa's (1999) trace-strength theory of timing and memory for event duration can account for pigeons' bias to “choose short” when retention intervals are introduced and to “choose long” when, following training with a fixed retention interval, retention intervals are shortened. However, it does not account for the failure of pigeons to choose short when the intertrial interval is distinct from the retention interval. That finding suggests that stimulus generalization (or ambiguity) between the intertrial interval and the retention interval may result in an effect that has been attributed to memory loss. Such artifacts must be eliminated before a theory of memory for event duration can be adequately tested. |
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Department of Psychology, University of Kentucky, Lexington 40506, USA. zentall@pop.uky.edu |
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0022-5002 |
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PMID:10605105 |
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Call Number |
refbase @ user @ |
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251 |
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Author |
Nevin, J.A.; Shettleworth, S.J. |
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Title |
An analysis of contrast effects in multiple schedules |
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Journal Article |
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Year |
1966 |
Publication |
Journal of the experimental analysis of behavior |
Abbreviated Journal |
J Exp Anal Behav |
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Volume |
9 |
Issue |
4 |
Pages |
305-315 |
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Keywords |
Animals; Birds; *Conditioning (Psychology); Conditioning, Operant; Discrimination Learning; *Extinction, Psychological; Male; Reaction Time; *Reinforcement (Psychology) |
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0022-5002 |
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PMID:5961499 |
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Call Number |
refbase @ user @ |
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392 |
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Author |
Kirkpatrick, J.F.; Liu, I.M.; Turner, J.W.J.; Naugle, R.; Keiper, R. |
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Title |
Long-term effects of porcine zonae pellucidae immunocontraception on ovarian function in feral horses (Equus caballus) |
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Journal Article |
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Year |
1992 |
Publication |
Journal of reproduction and fertility |
Abbreviated Journal |
J Reprod Fertil |
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Volume |
94 |
Issue |
2 |
Pages |
437-444 |
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Keywords |
Animals; Contraception, Immunologic/*veterinary; *Egg Proteins; Estrogens, Conjugated (USP)/urine; Female; Glycoproteins/*pharmacology; Horses/immunology/*physiology; *Membrane Glycoproteins; Ovary/drug effects/*physiology; Progesterone/metabolism; *Receptors, Cell Surface; Swine/immunology; Time Factors; Zona Pellucida/*immunology |
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Abstract |
Ten feral mares free-roaming in Maryland, USA, were inoculated with porcine zonae pellucidae (PZP) protein before the breeding season for three consecutive years (1988-90). Ovarian function was monitored for 51 days during the peak of the breeding season after the third annual PZP inoculation, in seven of these mares and in four untreated control mares, by means of urinary oestrone conjugates and nonspecific progesterone metabolites. None of the ten inoculated mares became pregnant in 1990, compared with 55% of 20 control mares, which included two of the four monitored for ovarian function. Three of the untreated mares demonstrated apparent normal ovarian activity, characterized by preovulatory oestrogen peaks, concurrent progesterone nadirs at ovulation, breeding activity, and luteal-phase progesterone increases after ovulation. Two of the seven monitored PZP-treated mares demonstrated ovulatory cycles that did not result in conception. One was pregnant as a result of conception in 1989 and demonstrated a normal, late-gestation, endocrine profile. The remaining four PZP-treated mares revealed no evidence of ovulation, and urinary oestrogen concentrations were significantly depressed. The experiments indicated that (i) a third consecutive annual PZP booster inoculation is greater than 90% effective in preventing pregnancies in mares and (ii) three consecutive years of PZP treatment may interfere with normal ovarian function as shown by markedly depressed oestrogen secretion. |
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Deaconess Research Institute, Billings, MT 59102 |
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0022-4251 |
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PMID:1317449 |
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no |
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Call Number |
refbase @ user @ |
Serial |
145 |
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