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Author |
Steinhoff, H.J.; Lieutenant, K.; Redhardt, A. |
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Title |
Conformational transition of aquomethemoglobin: intramolecular histidine E7 binding reaction to the heme iron in the temperature range between 220 K and 295 K as seen by EPR and temperature-jump measurements |
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Journal Article |
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Year |
1989 |
Publication |
Biochimica et Biophysica Acta |
Abbreviated Journal |
Biochim Biophys Acta |
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Volume |
996 |
Issue |
1-2 |
Pages |
49-56 |
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Keywords |
Animals; Electron Spin Resonance Spectroscopy; Heme; Histidine; Horses; Humans; Hydrogen-Ion Concentration; Methemoglobin/*ultrastructure; Motion; Protein Conformation; Temperature; Thermodynamics; Water |
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Abstract |
Temperature-dependent EPR and temperature-jump measurements have been carried out, in order to examine the high-spin to low-spin transition of aquomethemogobin (pH 6.0). Relaxation rates and equilibrium constants could be determined as a function of temperature. As a reaction mechanism for the high-spin to low-spin transition, the binding of N epsilon of His E7 to the heme iron had been proposed; the same mechanism had been suggested for the ms-effect, found in temperature-jump experiments on aquomethemoglobin. A comparison of the thermodynamic quantities, deduced form the measurements in this paper, gives evidence that indeed the same reaction is investigated in both cases. Our results and most of the findings of earlier studies on the spin-state transitions of aquomethemoglobin, using susceptibility, optical, or EPR measurements, can be explained by the transition of methemoglobin with H2O as ligand (with high-spin state at all temperatures) and methemoglobin with ligand N epsilon of His E7 (with a low-spin ground state). Thermal fluctuations of large amplitude have to be postulated for the reaction to take place, so this reaction may be understood as a probe for the study of protein dynamics. |
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Institut fur Biophysik, Ruhr-Universitat Bochum, F.R.G |
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0006-3002 |
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PMID:2544230 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3803 |
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Author |
Yamada, T.; Rojanasuphot, S.; Takagi, M.; Wungkobkiat, S.; Hirota, T. |
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Title |
Studies on an epidemic of Japanese encephalitis in the northern region of Thailand in 1969 and 1970 |
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Journal Article |
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Year |
1971 |
Publication |
Biken Journal |
Abbreviated Journal |
Biken J |
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Volume |
14 |
Issue |
3 |
Pages |
267-296 |
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Keywords |
Adolescent; Adult; Animals; Arboviruses/immunology; Buffaloes; Cattle; Chickens; Child; Child, Preschool; Cross Reactions; Culicidae; Dengue Virus/immunology; Disease Outbreaks; Ducks; Ecology; Encephalitis Virus, Japanese/immunology/isolation & purification; Encephalitis, Japanese/cerebrospinal fluid/*epidemiology/immunology/microbiology/mortality; Female; Hemagglutination Inhibition Tests; Hemorrhagic Fevers, Viral/epidemiology; Horses; Humans; Infant; Male; Mice; Neutralization Tests; Swine; Thailand |
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0006-2324 |
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PMID:4400462 |
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Equine Behaviour @ team @ |
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2728 |
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Author |
Meyer, W.; Pakur, M. |
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Title |
[Remarks on the domestic dog as an object of instruction for the education of the developing child] |
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Journal Article |
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Year |
1999 |
Publication |
Berliner und Munchener Tierarztliche Wochenschrift |
Abbreviated Journal |
Berl Munch Tierarztl Wochenschr |
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Volume |
112 |
Issue |
4 |
Pages |
131-138 |
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Keywords |
Animals; Animals, Domestic; *Bonding, Human-Pet; Character; Child; *Child Development; Child, Preschool; Cognition; *Dogs; Emotions; Empathy; Humans |
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Abstract |
Based on an intensive analysis of literature, the study summarizes problems involved in the significance of domesticated dogs as objects of instruction and assistants of the education of children. Several important topics are discussed in view of advances for children in families keeping dogs. Such topics are mainly related to a general socio-emotional level, the support of cognitive development and character formation. Further aspects are the acquisition of a sense of responsibility, and the development of self-confidence, a sense of social membership and security, as well as important attributes of character such as frankness, broad mindedness, and sympathetic understanding. Moreover, knowledge about the life cycle and functions of body organs can be conveyed, and the dog could, at least in part, substitute for brothers and sisters. Basically, positive attitudes towards animals in general, as well as nature and environment are supported. All topics are critically commented and considered to be realistic or not. The supporting role of parents, in particular, is emphasized. Parental commitment should include deep concern with the typical attributes of the dog breed desired, and optimal dog keeping conditions to prevent harm to the children. The final commentary lays special emphasis on negative features of domestication for a pet owner, and cautions against non-biological and illusionary ideas about domesticated animals. |
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Anatomisches Institut der Tierakztlichen Hochschule Hannover |
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German |
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Bemerkungen zum Haushund als Lehrobjekt und Erziehungshilfe fur das sich entwickelnde Kind |
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ISSN ![sorted by ISSN field, descending order (down)](img/sort_desc.gif) |
0005-9366 |
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PMID:10337055 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4155 |
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Author |
Dow, M.; Ewing, A.W.; Sutherland, I. |
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Title |
Studies on the behaviour of cyprinodont fish. III. The temporal patterning of aggression in Aphyosemion striatum (Boulenger) |
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Journal Article |
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Year |
1976 |
Publication |
Behaviour |
Abbreviated Journal |
Behaviour |
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Volume |
59 |
Issue |
3-4 |
Pages |
252-268 |
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Keywords |
*Aggression; Animals; *Behavior, Animal; Dominance-Subordination; *Fishes; Humans; Individuality; *Killifishes; Male; Time Factors |
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ISSN ![sorted by ISSN field, descending order (down)](img/sort_desc.gif) |
0005-7959 |
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PMID:1035107 |
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Call Number |
Equine Behaviour @ team @ |
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4151 |
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Author |
McClearn, G.E. |
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Title |
Behavioral genetics |
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Journal Article |
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Year |
1971 |
Publication |
Behavioral Science |
Abbreviated Journal |
Behav Sci |
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Volume |
16 |
Issue |
1 |
Pages |
64-81 |
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Keywords |
Amino Acid Metabolism, Inborn Errors; Animals; Aptitude; Behavior, Animal; Chromosome Aberrations; Cognition; Cytogenetics; Female; *Genetics, Behavioral; Genetics, Population; Humans; Intelligence; Mental Retardation; Mice; Models, Biological; Personality; Phenylketonurias; Pregnancy; Research; Schizophrenia; Sex Chromosome Aberrations; Twins |
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ISSN ![sorted by ISSN field, descending order (down)](img/sort_desc.gif) |
0005-7940 |
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PMID:5105941 |
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Equine Behaviour @ team @ |
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4150 |
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Author |
Cowley, J.J.; Griesel, R.D. |
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Title |
The effect on growth and behaviour of rehabilitating first and second generation low protein rats |
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Journal Article |
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Year |
1966 |
Publication |
Animal Behaviour. |
Abbreviated Journal |
Anim. Behav. |
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Volume |
14 |
Issue |
4 |
Pages |
506-517 |
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Keywords |
Animals; *Behavior, Animal; Diet Therapy; Dietary Proteins; Female; *Growth; Humans; Intelligence; Learning; Male; Mental Retardation/etiology; Protein Deficiency/*therapy; Rats |
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ISSN ![sorted by ISSN field, descending order (down)](img/sort_desc.gif) |
0003-3472 |
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PMID:6008473 |
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Equine Behaviour @ team @ |
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4119 |
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Author |
Hendricks, J.C.; Morrison, A.R. |
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Title |
Normal and abnormal sleep in mammals |
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Journal Article |
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Year |
1981 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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Volume |
178 |
Issue |
2 |
Pages |
121-126 |
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Keywords |
Animals; Cat Diseases/physiopathology; Cats; Cattle; Dog Diseases/physiopathology; Dogs; Dreams; Horses/physiology; Humans; Narcolepsy/physiopathology/veterinary; Sleep/*physiology; Sleep Apnea Syndromes/physiopathology/veterinary; Sleep Disorders/physiopathology/*veterinary; Sleep, REM/physiology |
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ISSN ![sorted by ISSN field, descending order (down)](img/sort_desc.gif) |
0003-1488 |
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PMID:7204232 |
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refbase @ user @ |
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101 |
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Author |
Kaiser, L.; Heleski, C.R.; Siegford, J.; Smith, K.A. |
![find record details (via OpenURL) openurl](img/xref.gif)
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Title |
Stress-related behaviors among horses used in a therapeutic riding program |
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Journal Article |
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Year |
2006 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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Volume |
228 |
Issue |
1 |
Pages |
39-45 |
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Adult; Animals; Behavior, Animal/*physiology; Child; *Disabled Persons; Female; Horses/*psychology; Humans; Male; *Mentally Disabled Persons; Occupational Therapy/methods; Recreation; Risk Factors; Stress/*veterinary |
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OBJECTIVE: To determine whether therapeutic riding resulted in higher levels of stress or frustration for horses than did recreational riding and whether therapeutic riding with at-risk individuals was more stressful for the horses than was therapeutic riding with individuals with physical or emotional handicaps. DESIGN: Observational study. ANIMALS: 14 horses in a therapeutic riding program. PROCEDURE: An ethogram of equine behaviors was created, and horses were observed while ridden by 5 groups of riders (recreational riders, physically handicapped riders, psychologically handicapped riders, at risk children, and special education children). Number of stress-related behaviors (ears pinned back, head raised, head turned, head tossed, head shaken, head down, and defecation) was compared among groups. RESULTS: No significant differences in mean number of stress-related behaviors were found when horses were ridden by recreational riders, physically handicapped riders, psychologically handicapped riders, or special education children. However, mean number of stress-related behaviors was significantly higher when horses were ridden by the at-risk children. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that for horses in a therapeutic riding program, being ridden by physically or psychologically handicapped individuals is no more stressful for the horses than is being ridden in the same setting by recreational riders. However, at-risk children caused more stress to the horses, suggesting that the time horses are ridden by at-risk children should be limited both daily and weekly. |
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Human-Animal Bond Initiative, College of Nursing, Michigan State University, East Lansing, MI 48824, USA |
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0003-1488 |
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PMID:16426164 |
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1879 |
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Author |
Kaiser, L.; Smith, K.A.; Heleski, C.R.; Spence, L.J. |
![find record details (via OpenURL) openurl](img/xref.gif)
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Title |
Effects of a therapeutic riding program on at-risk and special education children |
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Journal Article |
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Year |
2006 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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Volume |
228 |
Issue |
1 |
Pages |
46-52 |
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Keywords |
Adolescent; Anger; Animals; *Bonding, Human-Pet; Child; Child Behavior; *Child Psychology; Disabled Persons/*psychology/rehabilitation; Female; Horses; Humans; Mainstreaming (Education); Male; Mothers/*psychology; Occupational Therapy/*methods; Recreation; Self Efficacy; Sports/*psychology |
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OBJECTIVE: To determine the effects of a therapeutic riding program on psychosocial measurements among children considered at risk for poor performance or failure in school or life and among children in special education programs. DESIGN: Observational study. POPULATION: 17 at-risk children (6 boys and 11 girls) and 14 special education children (7 boys and 7 girls). PROCEDURE: For the at-risk children, anger, anxiety, perceived self-competence, and physical coordination were assessed. For the special education children, anger and cheerfulness were measured, and the children's and their mothers' perceptions of the children's behavior were assessed. Measurements were made before and after an 8-session therapeutic riding program. RESULTS: For boys enrolled in the special education program, anger was significantly decreased after completion of the riding program. The boys' mothers also perceived significant improvements in their children's behavior after completion of the program. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that an 8-session therapeutic riding program can significantly decrease anger in adolescent boys in a special education program and positively affect their mothers' perception of the boys' behavior. |
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Human-Animal Bond Initiative, College of Nursing, Michigan State University, East Lansing, MI 48824, USA |
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ISSN ![sorted by ISSN field, descending order (down)](img/sort_desc.gif) |
0003-1488 |
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PMID:16426165 |
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1880 |
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Author |
Madigan, J.E.; Bell, S.A. |
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Title |
Owner survey of headshaking in horses |
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Journal Article |
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Year |
2001 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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Volume |
219 |
Issue |
3 |
Pages |
334-337 |
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Keywords |
Animals; Anti-Allergic Agents/*therapeutic use; *Behavior, Animal/drug effects; Cyproheptadine/*therapeutic use; Data Collection; Diagnosis, Differential; Female; Horse Diseases/diagnosis/drug therapy/*etiology; Horses; Humans; Male; Questionnaires; Seasons |
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OBJECTIVE: To determine signalment, history, clinical signs, duration, seasonality, and response to various treatments reported by owners for headshaking in horses. DESIGN: Owner survey. ANIMALS: 109 horses with headshaking. PROCEDURE: Owners of affected horses completed a survey questionnaire. RESULTS: 78 affected horses were geldings, 29 were mares, and 2 were stallions. Mean age of onset was 9 years. Headshaking in 64 horses had a seasonal component, and for most horses, headshaking began in spring and ceased in late summer or fall. The most common clinical signs were shaking the head in a vertical plane, acting like an insect was flying up the nostril, snorting excessively, rubbing the muzzle on objects, having an anxious expression while headshaking, worsening of clinical signs with exposure to sunlight, and improvement of clinical signs at night. Treatment with antihistamines, nonsteroidal anti-inflammatory drugs, corticosteroids, antimicrobials, fly control, chiropractic, and acupuncture had limited success. Sixty-one horses had been treated with cyproheptadine; 43 had moderate to substantial improvement. CONCLUSIONS AND CLINICAL RELEVANCE: Headshaking may have many causes. A large subset of horses have similar clinical signs including shaking the head in a vertical plane, acting as if an insect were flying up the nostrils, and rubbing the muzzle on objects. Seasonality and worsening of clinical signs with exposure to light are also common features of this syndrome. Geldings and Thoroughbreds appear to be overrepresented. Cyproheptadine treatment was beneficial in more than two thirds of treated horses. |
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Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA |
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ISSN ![sorted by ISSN field, descending order (down)](img/sort_desc.gif) |
0003-1488 |
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PMID:11497047 |
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refbase @ user @ |
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1916 |
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