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Author |
Douglas Wilson, A. |
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Title |
The effects of diet on blood glucose, insulin, gastrin and the serum tryptophan: Large neutral amino acid ratio in foals |
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Journal Article |
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Year |
2006 |
Publication |
The Veterinary Journal |
Abbreviated Journal |
Vet J |
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Diet; Horse; Insulin; Gastrin; Tryptophan |
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Abstract  |
High carbohydrate diets can affect the health and behaviour of foals, but the mechanisms are not always fully understood. The objective of this study was to compare the effects of feeding a starch and sugar (SS), or a fat (oil) and fibre (FF) rich diet to two groups of eight foals. Diets were fed from 4 to 42 weeks of age, alongside ad libitum forage. Faecal pH levels did not differ significantly between groups and endoscopic examination showed that the gastric mucosa was healthy in both groups at 25 and 42 weeks of age. At 40 weeks of age, SS foals had significantly higher total blood glucose and lower total blood gastrin than FF foals during the 6h period following ingestion of their respective diets, but insulin levels did not differ significantly. The ratio between serum tryptophan and other large neutral amino acids showed a trend towards an interaction between diet and sampling time. The results provide preliminary information about the effects of diet on the physiology of young horses. |
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School of Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU, UK |
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Amanda J. Badnell-Watersb, Rachel Biceb, Ailison Kellandb, Pat A. Harrisc and Christine J. Nicol |
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English |
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1090-0233 |
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PMID:16945560 |
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refbase @ user @ |
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63 |
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Author |
Robitaille, J.; Brouillette, C.; Lemieux, S.; Perusse, L.; Gaudet, D.; Vohl, M.C. |
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Title |
Plasma concentrations of apolipoprotein B are modulated by a gene-diet interaction effect between the LFABP T94A polymorphism and dietary fat intake in French-Canadian men |
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Journal Article |
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Year |
2004 |
Publication |
Molecular Genetics and Metabolism |
Abbreviated Journal |
Mol Genet Metabol |
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Volume |
82 |
Issue |
4 |
Pages |
296-303 |
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Keywords |
Apolipoprotein B; Gene-diet interaction; Liver fatty acid-binding protein; Metabolic syndrome |
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Abstract |
Hyperapobetalipoproteinemia is a common feature of the metabolic syndrome and could result from the interaction between genetic and dietary factors. The objective of this study was to verify whether dietary fat intake interacts with the T94A polymorphism of the liver fatty acid-binding protein (LFABP) gene to modulate plasma apolipoprotein (apo) B levels. Dietary fat and saturated fat intakes were obtained by a dietitian-administered food frequency questionnaire and the LFABP T94A genotype was determined by a PCR-RFLP based method in 623 French-Canadian men recruited through the Chicoutimi Lipid Clinic (279 T94/T94, 285 T94/A94, and 59 A94/A94). The LFABP T94A polymorphism was not associated with plasma apo B levels when fat intake was not taken into consideration. However, in a model including the polymorphism, fat intake expressed as a percentage of total energy intake, the interaction term and covariates, the variance in apo B concentrations was partly explained by the LFABP T94A polymorphism (5.24%, p=0.01) and by the LFABP T94A * fat interaction (6.25%, p=0.005). Results were similar when saturated fat replaced fat intake in the model (4.49%, p=0.02 for LFABP T94A and 6.43%, p=0.004 for the interaction). Moreover, in men consuming more than 30% of energy from fat, the odds ratio for having plasma apo B levels above 1.04 g/L for A94 carriers was of 0.40 (p=0.02) compared to T94/T94 homozygotes. Results were similar for carriers of the A94 allele consuming more than 10% of energy from saturated fat (OR: 0.32, p=0.005). In conclusion, T94/T94 exhibit higher apo B levels whereas carriers of the A94 allele seem to be protected against high apo B levels when consuming a high fat and saturated fat diet. These findings reinforce the importance to take into account gene-diet interactions in the prevention and management of the metabolic syndrome. |
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refbase @ user @ |
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799 |
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Author |
Laut, J.E.; Houpt, K.A.; Hintz, H.F.; Houpt, T.R. |
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Title |
The effects of caloric dilution on meal patterns and food intake of ponies |
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Journal Article |
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Year |
1985 |
Publication |
Physiology & behavior |
Abbreviated Journal |
Physiol. Behav. |
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Volume |
35 |
Issue |
4 |
Pages |
549-554 |
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Keywords |
Animals; Body Weight; *Diet; Energy Intake; *Feeding Behavior; Homeostasis; Horses/*physiology; Male |
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Abstract |
In order to determine if horses will increase their intake in response to caloric dilution, four pony geldings were fed ad lib a mixed grain diet either undiluted (3.4 Mcal/kg of digestible energy) or diluted (wt/wt) with 25% sawdust (2.6 Mcal/kg) or with 50% sawdust (1.7 Mcal/kg). The mean daily caloric intake was 17,457 kcal (3.4 Mcal diet), 17,546 kcal (2.6 Mcal diet) and 12,844 kcal (1.7 Mcal). The mean time spent eating was 246 (3.4 Mcal), 351 (2.6 Mcal), and 408 (1.7 Mcal) minutes/day. Meal size increased and meal frequency decreased with increasing dilution. The median long survivorships of intermeal intervals were 6.4 min (3.4 Mcal), 3.95 min (2.6 Mcal) and 4.91 min (1.7 Mcal). Ponies responded to caloric dilution by increasing the volume of intake to maintain caloric intake when the diet had 25% diluent. When the diet was diluted by 50%, intake was increased, but not at a rate adequate to maintain caloric intake. However, the ponies were able to maintain body weight. |
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0031-9384 |
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PMID:4070429 |
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refbase @ user @ |
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52 |
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Katz, M.; Lachlan, R.F. |
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Title |
Social learning of food types in zebra finches (Taenopygia guttata) is directed by demonstrator sex and feeding activity |
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Journal Article |
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Year |
2003 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
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6 |
Issue |
1 |
Pages |
11-16 |
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Keywords |
Animals; Color; Diet; *Feeding Behavior; Female; *Learning; Male; Sex Factors; *Social Behavior; *Songbirds |
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Abstract |
In this study we examined how social learning of feeding preferences by zebra finches was affected by the identity of different demonstrators. We presented adult zebra finches with two demonstrators, one male and one female, that exhibited different food choices, and we recorded their subsequent preference when given a choice between the two food types. Previously it was found that young zebra finches' patterns of social learning are affected by the sex of the individual demonstrating a feeding behaviour. This result could be explained by the lack of exposure these animals had to the opposite sex, or by their mating status. Therefore, we investigated the social learning preferences of adult mated zebra finches. We found the same pattern of directed social learning of a different type of feeding behaviour (food colour): female zebra finches preferred the colour of food eaten by male demonstrators, whereas male zebra finches showed little evidence of any preference for the colour of food eaten by female demonstrators. Furthermore, we found that female observers' preferences were biased by demonstrators' relative feeding activity: the female demonstrator was only ever preferred if it ate less than its male counterpart. |
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Institute of Evolutionary and Ecological Science, University of Leiden, Kaiserstraat 63, 2311GP, Leiden, The Netherlands |
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1435-9448 |
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PMID:12658531 |
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Call Number |
Equine Behaviour @ team @ |
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2585 |
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Author |
Brown, R.F.; Houpt, K.A.; Schryver, H.F. |
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Title |
Stimulation of food intake in horses by diazepam and promazine |
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Journal Article |
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Year |
1976 |
Publication |
Pharmacology, biochemistry, and behavior |
Abbreviated Journal |
Pharmacol Biochem Behav |
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5 |
Issue |
4 |
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495-497 |
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Age Factors; Animals; Diazepam/*pharmacology; Diet; Feeding Behavior/*drug effects; Female; Horses/*physiology; Male; Promazine/*pharmacology; Stimulation, Chemical |
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In two adult horses doses of 0.02-0.03 mg/kg diazepam, intravenously, increased 1 hr intake 54-75% above control levels. Intake was stimulated when the diet was a high grain, calorically dense one and also when the diet was a high fiber, calorically dilute one. Two young rapidly growing weanling horses showed an even more pronounced stimulation of intake. Following diazepam 1 hr intake was increased 105-240% above control lelvels. Promazine at a dose of 0.5 mg/kg also stimulated intake in adult horses, but not as markedly as did diazepam. A transquilizer and a neuroleptic appear to have a stimulatory eff upon short-term intake in horses. |
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0091-3057 |
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PMID:1005496 |
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refbase @ user @ |
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60 |
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Author |
Turpeinen, O. |
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Title |
Effect of cholesterol-lowering diet on mortality from coronary heart disease and other causes |
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Journal Article |
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Year |
1979 |
Publication |
Circulation |
Abbreviated Journal |
Circulation |
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59 |
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1 |
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1-7 |
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Keywords |
Coronary Disease/blood/*mortality/prevention & control; Dairy Products; *Dietary Fats; *Fats, Unsaturated; Finland; Humans; Hypercholesterolemia/complications/*diet therapy/mortality; Male; Middle Aged; Neoplasms/mortality |
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International statistics indicate that there is a close correlation between the consumption of saturated fats (dairy fats and meat fats) and the mortality from coronary heart disease (CHD), and this conception has been confirmed by many epidemiological studies. Such studies alone, however, cannot prove the existence of a cause-and-effect relationship between these two variables; dietary intervention trials are needed. The Finnish Mental Hospital Study was such a trial, conducted in two hospitals near Helsinki in 1959--1971. Practically total replacement of dairy fats by vegetable oils in the diets of these hospitals was followed by a substantial reduction in the mortality of men from CHD. Total mortality also appeared to be reduced. As to the causes of death other than CHD, none was significantly influenced by dietary change. This was also true for malignant neoplasms. To alleviate the burden of CHD on public health, many investigators have recommended important changes in the quantity and quality of dietary fats. |
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0009-7322 |
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PMID:758101 |
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refbase @ user @ |
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33 |
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Author |
Goodwin, D.; Davidson, H.P.B.; Harris, P. |
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Title |
Selection and acceptance of flavours in concentrate diets for stabled horses |
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Journal Article |
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Year |
2005 |
Publication |
Applied Animal Behaviour Science |
Abbreviated Journal |
Appl. Anim. Behav. Sci. |
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Volume |
95 |
Issue |
3-4 |
Pages |
223-232 |
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Keywords |
Horse; Flavour; Diet; Selection; Acceptance |
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Like most large grazing herbivores, horses select their food based on visual cues, odour, taste, texture, availability and variety. There is relatively little published information about the role of flavour in diet selection by domestic horses in comparison with other domestic and companion animals. However, previous trials investigating effects of diet flavour in stabled horses indicated significant effects on foraging behaviour and selection. In this series of three trials we aimed to determine relative acceptance by presenting flavour preference tests to eight horses. Horses were stabled and fed hay ad lib on trial data collection days plus a standard unflavoured concentrate ration at 7:30 a.m. In Trial 1, 15 flavours were separately presented in standard 100 g cereal by-product meals and the trial was replicated. Quantity consumed, time of completion, partial rejection or refusal were recorded. Order of presentation was determined by a Latin Square design. Trial data were collected on five sampling days, separated by a minimum of 1 day. Horses were presented with six flavoured meals daily; minimum 1 h between the meals. Twelve flavours were universally accepted and of these the eight flavours with fastest mean consumption times (banana, carrot, cherry, cumin, fenugreek, oregano, peppermint and rosemary) were presented in paired preference tests in Trial 2. In Trial 2, all paired combinations of the eight flavours were presented, in two tests per day at noon and 4 p.m. Presentations of the same flavour were separated by at least 1 day. Paired presentations were in 300 g cereal by-product. Presentations were terminated when approximately half of the total amount presented had been consumed. Flavour preferences were expressed as a ratio from 0 (rejection) to 1 (exclusive consumption). Paired flavour preferences produced the following rank order: fenugreek, banana, cherry, rosemary, cumin, carrot, peppermint, oregano. In Trial 3, relative consumption times of mineral pellets flavoured with fenugreek and banana were significantly reduced in comparison with unflavoured pellets. In these short-term trials, flavour had significant effects on diet acceptance, selection and consumption times. |
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Equine Behaviour @ team @ |
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3643 |
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Author |
Nicol, C.J.; Davidson, H.P.D.; Harris, P.A.; Waters, A.J.; Wilson, A.D. |
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Title |
Study of crib-biting and gastric inflammation and ulceration in young horses |
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Journal Article |
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Year |
2002 |
Publication |
The Veterinary record |
Abbreviated Journal |
Vet. Rec. |
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Volume |
151 |
Issue |
22 |
Pages |
658-662 |
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Keywords |
Animal Husbandry/methods; Animals; Antacids/therapeutic use; *Behavior, Animal; Diet/veterinary; Endoscopy, Gastrointestinal/veterinary; Feces/chemistry; Female; Gastritis/diet therapy/physiopathology/*veterinary; Horse Diseases/diet therapy/*physiopathology/psychology; Horses; Hydrogen-Ion Concentration; Male; Random Allocation; Stereotyped Behavior/*physiology; Stomach Ulcer/diet therapy/physiopathology/*veterinary; Treatment Outcome; Weaning |
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Nineteen young horses that had recently started to perform the stereotypy of crib-biting were compared with 16 non-stereotypic horses for 14 weeks. After initial observations of their behaviour and an endoscopic examination of the condition of their stomachs, the horses were randomly allocated to a control or an antacid diet At the start of the trial, the stomachs of the crib-biting foals were significantly more ulcerated and inflamed than the stomachs of the normal foals. In addition, the faecal pH of the crib-biting foals (6.05) was significantly lower than that of the normal foals (6.58). The antacid diet resulted in a significant improvement in the condition of the horses' stomachs. The crib-biting behaviour declined in most of the foals, regardless of their diet, but tended to decline to a greater extent in the foals on the antacid diet. |
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Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU |
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0042-4900 |
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PMID:12498408 |
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refbase @ user @ |
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83 |
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Jeong, S.; Han, M.; Lee, H.; Kim, M.; Kim, J.; Nicol, C.J.; Kim, B.H.; Choi, J.H.; Nam, K.-H.; Oh, G.T.; Yoon, M. |
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Title |
Effects of fenofibrate on high-fat diet-induced body weight gain and adiposity in female C57BL/6J mice |
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Journal Article |
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Year |
2004 |
Publication |
Metabolism: clinical and experimental |
Abbreviated Journal |
Metabolism |
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53 |
Issue |
10 |
Pages |
1284-1289 |
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Keywords |
Adipose Tissue/*anatomy & histology/drug effects; Animals; Antilipemic Agents/*pharmacology; Body Composition/*drug effects; Body Weight/drug effects; Dietary Fats/*pharmacology; Eating/drug effects; Fatty Acids/metabolism; Female; Gene Expression Regulation/drug effects; Leptin/metabolism; Liver/metabolism; Mice; Mice, Inbred C57BL; Ovariectomy; Procetofen/*pharmacology; RNA, Messenger/biosynthesis/genetics; Receptors, Cytoplasmic and Nuclear/biosynthesis/genetics/metabolism; Transcription Factors/biosynthesis/genetics/metabolism; Weight Gain/*drug effects |
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Our previous study suggested that fenofibrate affects obesity and lipid metabolism in a sexually dimorphic manner in part through the differential activation of hepatic peroxisome proliferator-activated receptor alpha (PPARalpha) in male and female C57BL/6J mice. To determine whether fenofibrate reduces body weight gain and adiposity in female sham-operated (Sham) and ovariectomized (OVX) C57BL/6J mice, the effects of fenofibrate on not only body weight, white adipose tissue (WAT) mass, and food intake, but also the expression of both leptin and PPARalpha target genes were measured. Compared to their respective low-fat diet-fed controls, both Sham and OVX mice exhibited increases in body weight and WAT mass when fed a high-fat diet. Fenofibrate treatment decreased body weight gain and WAT mass in OVX, but not in Sham mice. Furthermore, fenofibrate increased the mRNA levels of PPARalpha target genes encoding peroxisomal enzymes involved in fatty acid beta-oxidation, and reduced apolipoprotein C-III (apo C-III) mRNA, all of which were expressed at higher levels in OVX compared to Sham mice. However, leptin mRNA levels were found to positively correlate with WAT mass, and food intake was not changed in either OVX or Sham mice following fenofibrate treatment. These results suggest that fenofibrate differentially regulates body weight and adiposity due in part to differences in PPARalpha activation, but not to differences in leptin production, between female OVX and Sham mice. |
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Department of Life Sciences, Mokwon University, Taejon, Korea |
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0026-0495 |
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PMID:15375783 |
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refbase @ user @ |
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72 |
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Author |
Nicol, C.J.; Badnell-Waters, A.J.; Bice, R.; Kelland, A.; Wilson, A.D.; Harris, P.A. |
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Title |
The effects of diet and weaning method on the behaviour of young horses |
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Journal Article |
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Year |
2005 |
Publication |
Applied Animal Behaviour Science |
Abbreviated Journal |
Appl. Anim. Behav. Sci. |
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Volume |
95 |
Issue |
3-4 |
Pages |
205-221 |
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Keywords |
Horse; Diet; Weaning; Temperament test |
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Abstract |
The effects of diet on horse behaviour have not previously been quantified in detail. In this study, we examined the behaviour of 17 foals from the age of 2 to 40 weeks. Each foal received either a starch and sugar (SS) diet or a fat and fibre (FF) diet. The two diets contained similar digestible energy, crude protein and micronutrients, but differed in the fat and non-structural carbohydrate balance. The baseline behaviour of the foals was observed every 2 weeks by focal animal sampling. Additional behavioural observations were conducted when the foals were weaned by one of two methods. Approximately 2 months after weaning, the temperament and tractability of the young horses was assessed using standardised tests. Responses to a novel object, to a novel person, and during a handling test were observed and quantified. Horses grew well on both diets with no apparent effects of diet on growth rate or baseline behaviour. Immediately after weaning, horses receiving the FF diet cantered less frequently (F = 5.10; p < 0.05), for a shorter duration (F = 7.23; p < 0.05) and appeared to be more settled. Foals that were barn-weaned appeared more stressed than foals that were paddock-weaned. In the temperament tests, horses receiving the FF diet spent significantly more time investigating (F = 6.78; p < 0.05), and less time looking at (F = 7.93; p < 0.05), the novel object than horses receiving the SS diet. They also spent less time walking away from the novel person (F = 5.16; p < 0.05) and their time taken to complete the handling test was significantly lower (F = 8.72; p = 0.01). Overall, the horses that received the FF diet appeared less distressed immediately after weaning and seemed calmer and more inquisitive during a range of temperament tests. |
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Equine Behaviour @ team @ |
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3642 |
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