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Author (up) Baum, M.J. doi  openurl
  Title Mammalian animal models of psychosexual differentiation: when is 'translation' to the human situation possible? Type Journal Article
  Year 2006 Publication Hormones and Behavior Abbreviated Journal Horm Behav  
  Volume 50 Issue 4 Pages 579-588  
  Keywords Animals; Estradiol/*physiology; Female; *Gender Identity; Humans; Hypothalamus/anatomy & histology/physiology; Male; Models, Animal; Sexual Behavior/physiology/psychology; Sexual Behavior, Animal/*physiology; Testosterone/*physiology  
  Abstract Clinical investigators have been forced primarily to use experiments of nature (e.g., cloacal exstrophy; androgen insensitivity, congenital adrenal hyperplasia) to assess the contribution of fetal sex hormone exposure to the development of male- and female-typical profiles of gender identity and role behavior as well as sexual orientation. In this review, I summarize the results of numerous correlative as well as mechanistic animal experiments that shed significant light on general neuroendocrine mechanisms controlling the differentiation of neural circuits controlling sexual partner preference (sexual orientation) in mammalian species including man. I also argue, however, that results of animal studies can, at best, provide only indirect insights into the neuroendocrine determinants of human gender identity and role behaviors.  
  Address Department of Biology, Boston University, 5 Cummington Sreet, Boston, MA 02215, USA. baum@bu.edu  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0018-506X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16876166 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4190  
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