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	Author	Griffin, B.
	Title	The use of fecal markers to facilitate sample collection in group-housed cats			Type	Journal Article
	Year	2002	Publication	Contemporary Topics in Laboratory Animal Science / American Association for Laboratory Animal Science	Abbreviated Journal	Contemp Top Lab Anim Sci
	Volume	41	Issue	2	Pages	51-56
	Keywords	Animals; Behavior, Animal; Biological Markers/analysis; Cats/physiology/psychology; Diet/veterinary; Feces/chemistry; Food Coloring Agents/analysis; Housing, Animal; Individuality; Plastics/analysis; Specimen Handling/methods/veterinary
	Abstract	The provision of proper social housing is a priority when designing an experiment using domestic cats as laboratory animals. When animals are group-housed, studies requiring analysis of stool samples from individual subjects pose difficulty in sample collection and identification. In this study, commercially available concentrated food colorings (known as bakers pastes) were used as fecal markers in group-housed cats. Cats readily consumed 0.5 ml of bakers paste food coloring once daily in canned cat food. Colorings served as fecal markers by imparting a distinct color to each cat s feces, allowing identification in the litter box. In addition, colored glitter (1/8 teaspoon in canned food) was fed to cats and found to be a reliable fecal marker. Long-term feeding of colorings and glitter was found to be safe and effective at yielding readily identifiable stools.
	Address	Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Alabama 36841, USA
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	1060-0558	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:11958604			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	4165
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	Author	Pollmann, U.
	Title	[Keeping of horses in circus and show businesses]			Type	Journal Article
	Year	2002	Publication	DTW. Deutsche Tierarztliche Wochenschrift	Abbreviated Journal	Dtsch Tierarztl Wochenschr
	Volume	109	Issue	3	Pages	126-129
	Keywords	Animal Husbandry/methods; Animal Welfare; Animals; Behavior, Animal; Horses; Housing, Animal; Humans; Reward
	Abstract	The conditions under which horses are kept and the performance of acts in the circus ring may give rise to animal protection-relevant aspects for circus and show horses. A number of intolerable conditions under which horses are kept and procedures adopted for the work with circus and show horses are described. In addition, attention is drawn to monitoring methods capable of exposing the deplorable shortcomings of these businesses.
	Address	Fachbereich Ethologie und Tierschutz des Chemischen und Veterinaruntersuchungsamtes Freiburg. Ursula.Pollmann@cvuafr.bwl.de
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	German	Summary Language		Original Title	Pferdehaltung in Zirkus- und Schaustellerbetrieben
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0341-6593	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:11963363			Approved	no
	Call Number	refbase @ user @			Serial	1914
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	Author	Haruta, N.; Kitagawa, T.
	Title	Time-resolved UV resonance Raman investigation of protein folding using a rapid mixer: characterization of kinetic folding intermediates of apomyoglobin			Type	Journal Article
	Year	2002	Publication	Biochemistry	Abbreviated Journal	Biochemistry
	Volume	41	Issue	21	Pages	6595-6604
	Keywords	Animals; Apoproteins/chemistry; Circular Dichroism; Holoenzymes/chemistry; Horses; Hydrochloric Acid/chemistry; Hydrogen-Ion Concentration; Imidazoles/chemistry; Kinetics; Models, Molecular; Myoglobin/chemistry; Peptide Fragments/chemistry; Protein Folding; Protein Structure, Secondary; Spectrum Analysis, Raman/methods; Tryptophan/*chemistry; Ultraviolet Rays; Whales
	Abstract	The 244-nm excited transient UV resonance Raman spectra are observed for the refolding intermediates of horse apomyoglobin (h-apoMb) with a newly constructed mixed flow cell system, and the results are interpreted on the basis of the spectra observed for the equilibrium acid unfolding of the same protein. The dead time of mixing, which was determined with the appearance of UV Raman bands of imidazolium upon mixing of imidazole with acid, was 150 micros under the flow rate that was adopted. The pH-jump experiments of h-apoMb from pH 2.2 to 5.6 conducted with this device demonstrated the presence of three folding intermediates. On the basis of the analysis of W3 and W7 bands of Trp7 and Trp14, the first intermediate, formed before 250 micros, involved incorporation of Trp14 into the alpha-helix from a random coil. The frequency shift of the W3 band of Trp14 observed for this process was reproduced with a model peptide of the A helix when it forms the alpha-helix. In the second intermediate, formed around 1 ms after the start of refolding, the surroundings of both Trp7 and Trp14 were significantly hydrophobic, suggesting the formation of the hydrophobic core. In the third intermediate appearing around 3 ms, the hydrophobicity was relaxed to the same level as that of the pH 4 equilibrium intermediate, which was investigated in detail with the stationary state technique. The change from the third intermediate to the native state needs more time than 40 ms, while the appearance of the native spectrum after the mixing of the same solutions was confirmed separately.
	Address	School of Mathematical and Physical Sciences, The Graduate University for Advanced Studies, Myodaiji, Okazaki 444-8585, Japan
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0006-2960	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12022863			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	3785
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	Author	Turner, A.; Kirkpatrick, J.F.
	Title	Effects of immunocontraception on population, longevity and body condition in wild mares (Equus caballus)			Type	Journal Article
	Year	2002	Publication	Reproduction (Cambridge, England) Supplement	Abbreviated Journal	Reprod Suppl
	Volume	60	Issue		Pages	187-195
	Keywords	Animals; Animals, Wild; Antigens/administration & dosage; Body Constitution; Contraception, Immunologic/methods/veterinary; Egg Proteins/administration & dosage; Female; Horses; Longevity; Membrane Glycoproteins/administration & dosage; Population Control; Population Dynamics; Receptors, Cell Surface; Swine; Vaccines, Contraceptive/administration & dosage
	Abstract	Contraception is becoming a common approach for the management of captive and wild ungulates yet there are few data for contraceptive effects on entire populations. Management-level treatment of mares with porcine zona pellucida (PZP) vaccine resulted in zero population growth of the Assateague Island wild horse population within 1 year of initiation of treatment. Contraceptive efficacy was 90% for mares treated twice in the first year and annually thereafter. For mares given a single initial inoculation, contraceptive efficacy was 78%. The effort required to achieve zero population growth decreased, as 95, 83 and 84% of all adult mares were treated in each of the first 3 years, compared with 59 and 52% during the last 2 years. Mortality rates for mares and foals after the initiation of management-level treatments decreased below historic and pretreatment mortality rates of approximately 5%. Two new age classes have appeared among treated animals (21-25 years and > 25 years), indicating an increase in longevity among treated animals. Body condition scores for all horses, all adult mares and non-lactating mares increased significantly between summer 1989 and autumn 1999 but did not change significantly in lactating mares. These results provide reliable data for the construction of realistic models for contraceptive management of free-roaming or captive ungulate populations.
	Address	Assateague Island National Seashore, Berlin, MD 21811, USA
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	1477-0415	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12220158			Approved	no
	Call Number	refbase @ user @			Serial	142
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	Author	Kirkpatrick, J.F.; Turner, A.
	Title	Reversibility of action and safety during pregnancy of immunization against porcine zona pellucida in wild mares (Equus caballus)			Type	Journal Article
	Year	2002	Publication	Reproduction (Cambridge, England) Supplement	Abbreviated Journal	Reprod Suppl
	Volume	60	Issue		Pages	197-202
	Keywords	Animals; Animals, Wild; Antigens/administration & dosage; Contraception, Immunologic/methods/veterinary; Egg Proteins/administration & dosage; Female; Fertility; Horses; Immunization, Secondary/veterinary; Membrane Glycoproteins/administration & dosage; Population Control; Pregnancy; Receptors, Cell Surface; Safety; Swine; Time Factors; Vaccines, Contraceptive/*administration & dosage
	Abstract	Contraceptive management of publicly valued wildlife species requires safeguards to ensure that these populations are preserved in a healthy state. In addition, reversibility of contraceptive effects and safety in pregnant animals are major concerns. A population of wild horses has been immunized against porcine zona pellucida (PZP) over a 12 year period on Assateague Island National Seashore, MD (ASIS). Mares initially received one or two 65 microg inoculations and once a year 65 microg booster inoculations, all delivered by dart. All young mares aged > 2 years were treated with PZP for 3 consecutive years regardless of whether they have bred successfully and they were then removed from treatment until they had foaled. All mares vaccinated for 1 or 2 consecutive years became fertile again and 69% of mares treated for 3 consecutive years returned to fertility. All five mares treated for 4 or 5 consecutive years have also returned to fertility, but over longer periods of time. Mares treated for 7 consecutive years have not returned to fertility, but several, while still infertile, have started ovulating again. There was no difference in survival rates between foals born to treated and untreated mares, and PZP treatment of pregnant mares did not affect subsequent fertility of their female offspring.
	Address	Science and Conservation Center, ZooMontana, Billings 59106, USA. zoolab@wtp.net
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	1477-0415	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12220160			Approved	no
	Call Number	refbase @ user @			Serial	141
Permanent link to this record



	Author	Waters, A.J.; Nicol, C.J.; French, N.P.
	Title	Factors influencing the development of stereotypic and redirected behaviours in young horses: findings of a four year prospective epidemiological study			Type	Journal Article
	Year	2002	Publication	Equine veterinary journal	Abbreviated Journal	Equine Vet J
	Volume	34	Issue	6	Pages	572-579
	Keywords	Age Factors; Animal Husbandry/methods; Animal Welfare; Animals; Behavior, Animal; Female; Horse Diseases/epidemiology/prevention & control/psychology; Horses; Housing, Animal; Longitudinal Studies; Male; Prevalence; Prospective Studies; Risk Factors; Stereotyped Behavior; Weaning
	Abstract	Stereotypies are invariant and repetitive behaviour patterns that seemingly have no function, which tend to develop in captive animals faced with insoluble problems and may be indicative of reduced welfare. A 4 year prospective study of the factors influencing the development of stereotypic and redirected behaviours (abnormal behaviour) in a population of 225 young Thoroughbred and part-Thoroughbred horses was conducted between 1995 and 1999. Abnormal behaviour affected 34.7% of the population. Multivariable analysis showed that foals of low- or middle-ranking mares were less likely to develop abnormal behaviour than foals of dominant mares (rate ratio (RR) 0.23, P<0.01; RR 0.48, P<0.01, respectively). Weaning by confinement in a stable or barn was associated with an increased rate of development of abnormal behaviour, compared with paddock-weaning (RR 2.19, P<0.05), and housing in barns, rather than at grass after weaning, was associated with a further increase (RR 2.54, P<0.01). Specific stereotypic and redirected behaviours were then considered as separate outcomes. Crib-biting was initiated by 10.5% of horses at median age 20 weeks, weaving by 4.6% of horses at median age 60 weeks, box-walking by 2.3% of horses at median age 64 weeks and wood-chewing by 30.3% of horses at median age 30 weeks. Wood-chewing developed at a lower rate in horses born to subordinate or mid-ranking mares than in horses born to dominant mares (RR 0.29, P<0.01; RR 0.41, P<0.01, respectively), and at a higher rate in horses kept in barns or stables rather than at grass after weaning (RR 4.49, P<0.001; RR 1A6, P<0.001, respectively). Feeding concentrates after weaning was associated with a 4-fold increase in the rate of development of crib-biting (RR 4.12, P = 0.02). The results of this study support the idea that simple changes in feeding, housing and weaning practices could substantially lower the incidence of abnormal behaviour in young horses.
	Address	University of Bristol, Department of Clinical Veterinary Science, Langford, Bristol, UK
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0425-1644	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12357996			Approved	no
	Call Number	refbase @ user @			Serial	84
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	Author	Goodwin, D.; Davidson, H.P.B.; Harris, P.
	Title	Foraging enrichment for stabled horses: effects on behaviour and selection			Type	Journal Article
	Year	2002	Publication	Equine Veterinary Journal	Abbreviated Journal	Equine Vet J
	Volume	34	Issue	7	Pages	686-691
	Keywords	Animal Feed; Animal Husbandry/methods; Animal Welfare; Animals; Behavior, Animal; Female; Horse Diseases/psychology; Horses/physiology; Housing, Animal; Male; Poaceae; Stereotyped Behavior; Videotape Recording
	Abstract	The restricted access to pasture experienced by many competition horses has been linked to the exhibition of stereotypic and redirected behaviour patterns. It has been suggested that racehorses provided with more than one source of forage are less likely to perform these patterns; however, the reasons for this are currently unclear. To investigate this in 4 replicated trials, up to 12 horses were introduced into each of 2 identical stables containing a single forage, or 6 forages for 5 min. To detect novelty effects, in the first and third trials the single forage was hay. In the second and fourth, it was the preferred forage from the preceding trial. Trials were videotaped and 12 mutually exclusive behaviour patterns compared. When hay was presented as the single forage (Trials 1 and 3), all recorded behaviour patterns were significantly different between stables; e.g. during Trial 3 in the 'Single' stable, horses looked over the stable door more frequently (P<0.001), moved for longer (P<0.001), foraged on straw bedding longer (P<0.001), and exhibited behaviour indicative of motivation to search for alternative resources (P<0.001) more frequently. When a previously preferred forage was presented as the single forage (Trials 2 and 4) behaviour was also significantly different between stables, e.g in Trial 4 horses looked out over the stable door more frequently (P<0.005) and foraged for longer in their straw bedding (P<0.005). Further study is required to determine whether these effects persist over longer periods. However, these trials indicate that enrichment of the stable environment through provision of multiple forages may have welfare benefits for horses, in reducing straw consumption and facilitating the expression of highly motivated foraging behaviour.
	Address	Anthrozoology Institute, University of Southampton, UK
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0425-1644	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12455839			Approved	no
	Call Number	refbase @ user @			Serial	1910
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	Author	Milgram, N.W.; Head, E.; Muggenburg, B.; Holowachuk, D.; Murphey, H.; Estrada, J.; Ikeda-Douglas, C.J.; Zicker, S.C.; Cotman, C.W.
	Title	Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy			Type	Journal Article
	Year	2002	Publication	Neuroscience and Biobehavioral Reviews	Abbreviated Journal	Neurosci Biobehav Rev
	Volume	26	Issue	6	Pages	679-695
	Keywords	Age Factors; Aging/physiology; Analysis of Variance; Animals; Antioxidants/pharmacology; Blood Chemical Analysis/methods; Cognition/physiology; Diet; Discrimination Learning/drug effects/physiology; Distance Perception/drug effects/physiology; Dogs/physiology; Female; Male; Psychomotor Performance/physiology; Retention (Psychology)/drug effects/physiology; Spatial Behavior/drug effects/physiology; Task Performance and Analysis; Time Factors; Vitamin E/blood
	Abstract	The landmark discrimination learning test can be used to assess the ability to utilize allocentric spatial information to locate targets. The present experiments examined the role of various factors on performance of a landmark discrimination learning task in beagle dogs. Experiments 1 and 2 looked at the effects of age and food composition. Experiments 3 and 4 were aimed at characterizing the cognitive strategies used in performance on this task and in long-term retention. Cognitively equivalent groups of old and young dogs were placed into either a test group maintained on food enriched with a broad-spectrum of antioxidants and mitochondrial cofactors, or a control group maintained on a complete and balanced food formulated for adult dogs. Following a wash-in period, the dogs were tested on a series of problems, in which reward was obtained when the animal responded selectively to the object closest to a thin wooden block, which served as a landmark. In Experiment 1, dogs were first trained to respond to a landmark placed directly on top of coaster, landmark 0 (L0). In the next phase of testing, the landmark was moved at successively greater distances (1, 4 or 10 cm) away from the reward object. Learning varied as a function of age group, food group, and task. The young dogs learned all of the tasks more quickly than the old dogs. The aged dogs on the enriched food learned L0 significantly more rapidly than aged dogs on control food. A higher proportion of dogs on the enriched food learned the task, when the distance was increased to 1cm. Experiment 2 showed that accuracy decreased with increased distance between the reward object and landmark, and this effect was greater in old animals. Experiment 3 showed stability of performance, despite using a novel landmark, and new locations, indicating that dogs learned the landmark concept. Experiment 4 found age impaired long-term retention of the landmark task. These results indicate that allocentric spatial learning is impaired in an age-dependent manner in dogs, and that age also affects performance when the distance between the landmark and target is increased. In addition, these results both support a role of oxidative damage in the development of age-associated cognitive dysfunction and indicate that short-term administration of a food enriched with supplemental antioxidants and mitochondrial cofactors can partially reverse the deleterious effects of aging on cognition.
	Address	Life Science Division, University of Toronto at Scarborough, 1265 Military Trail, Scarborough, Ont., Canada M1C 1A4. milgram@psych.utoronto.ca
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0149-7634	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12479842			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	2806
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	Author	Nicol, C.J.; Davidson, H.P.D.; Harris, P.A.; Waters, A.J.; Wilson, A.D.
	Title	Study of crib-biting and gastric inflammation and ulceration in young horses			Type	Journal Article
	Year	2002	Publication	The Veterinary record	Abbreviated Journal	Vet. Rec.
	Volume	151	Issue	22	Pages	658-662
	Keywords	Animal Husbandry/methods; Animals; Antacids/therapeutic use; Behavior, Animal; Diet/veterinary; Endoscopy, Gastrointestinal/veterinary; Feces/chemistry; Female; Gastritis/diet therapy/physiopathology/veterinary; Horse Diseases/diet therapy/physiopathology/psychology; Horses; Hydrogen-Ion Concentration; Male; Random Allocation; Stereotyped Behavior/physiology; Stomach Ulcer/diet therapy/physiopathology/*veterinary; Treatment Outcome; Weaning
	Abstract	Nineteen young horses that had recently started to perform the stereotypy of crib-biting were compared with 16 non-stereotypic horses for 14 weeks. After initial observations of their behaviour and an endoscopic examination of the condition of their stomachs, the horses were randomly allocated to a control or an antacid diet At the start of the trial, the stomachs of the crib-biting foals were significantly more ulcerated and inflamed than the stomachs of the normal foals. In addition, the faecal pH of the crib-biting foals (6.05) was significantly lower than that of the normal foals (6.58). The antacid diet resulted in a significant improvement in the condition of the horses' stomachs. The crib-biting behaviour declined in most of the foals, regardless of their diet, but tended to decline to a greater extent in the foals on the antacid diet.
	Address	Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	English	Summary Language		Original Title
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0042-4900	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12498408			Approved	no
	Call Number	refbase @ user @			Serial	83
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	Author	Ziegler, W.H.
	Title	[Endocrinological studies in arterial hypertension. Search for phaeochromocytoma]			Type	Journal Article
	Year	1976	Publication	Schweizerische Medizinische Wochenschrift	Abbreviated Journal	Schweiz Med Wochenschr
	Volume	106	Issue	34	Pages	1148-1150
	Keywords	Angiography; Blood Volume; Catecholamines/urine; Glucagon/diagnostic use; Histamine/diagnostic use; Humans; Hydrogen-Ion Concentration; Hypertension/etiology; Methods; Pheochromocytoma/complications/diagnosis; Tyramine/diagnostic use
	Abstract	Elevated urinary catecholamines and their metabolites are the only findings which confirm the presence of pheochromocytoma. This examination is of particular interest if carried out in urine produced after spontaneous hypertensive episodes. Pharmacologic tests when carried out under standard conditions have proven to be a reliable aid in cases of suspected pheochromocytoma. Roentgenographic studies, determination of local plasma catecholamine concentrations and blood volume control should be undertaken in these patients before surgical procedure.
	Address
	Corporate Author				Thesis
	Publisher		Place of Publication		Editor
	Language	German	Summary Language		Original Title	Endokrinologische Untersuchungen bei arterieller Hypertonie. Suche nach Phaochromozytom
	Series Editor		Series Title		Abbreviated Series Title
	Series Volume		Series Issue		Edition
	ISSN	0036-7672	ISBN		Medium
	Area		Expedition		Conference
	Notes	PMID:12561			Approved	no
	Call Number	Equine Behaviour @ team @			Serial	4047
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