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Author McGreevy, P.D.; Cripps, P.J.; French, N.P.; Green, L.E.; Nicol, C.J. openurl 
  Title Management factors associated with stereotypic and redirected behaviour in the thoroughbred horse Type Journal Article
  Year 1995 Publication Equine veterinary journal Abbreviated Journal Equine Vet J  
  Volume (down) 27 Issue 2 Pages 86-91  
  Keywords Animal Husbandry/*methods; Animals; Horse Diseases/psychology/*therapy; Horses; Risk Factors; *Stereotyped Behavior; Time Factors  
  Abstract A greater knowledge of the effect of management factors is required to investigate the ontogeny of abnormal behaviour in the stabled horse. A postal survey of racehorse (flat) trainers yielded information about 22 yard and management factors. The relationship of the factors to the prevalence of abnormal behaviour was analysed by logistic regression. Management factors related to the time spent in the stable showed the strongest associations with stereotypic behaviour. The risk of horses performing abnormal behaviour increased: 1) as the amount of forage fell below 6.8 kg/day, 2) when bedding types other than straw were used, 3) when the total number of horses on the yard was fewer than 75, 4) in association with box designs that minimised contact between neighbouring horses, 5) when hay, rather than other types of forage, was used.  
  Address Department of Animal Health and Husbandry, School of Veterinary Science, University of Bristol, Langford, UK  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:7607155 Approved no  
  Call Number refbase @ user @ Serial 91  
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Author Carroll, G.L.; Matthews, N.S.; Hartsfield, S.M.; Slater, M.R.; Champney, T.H.; Erickson, S.W. openurl 
  Title The effect of detomidine and its antagonism with tolazoline on stress-related hormones, metabolites, physiologic responses, and behavior in awake ponies Type Journal Article
  Year 1997 Publication Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons Abbreviated Journal Vet Surg  
  Volume (down) 26 Issue 1 Pages 69-77  
  Keywords Adrenergic alpha-Antagonists/administration & dosage/*pharmacology; Animals; Behavior, Animal/drug effects/physiology; Blood Glucose/metabolism; Blood Pressure/drug effects/physiology; Consciousness/physiology; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine/blood; Fatty Acids, Nonesterified/blood; Female; Heart Rate/drug effects/physiology; Horse Diseases/metabolism/physiopathology/psychology; Horses/blood/metabolism/*physiology; Hydrocortisone/blood; Hypnotics and Sedatives/administration & dosage/*pharmacology; Imidazoles/administration & dosage/*pharmacology; Injections, Intravenous; Male; Norepinephrine/blood; Receptors, Adrenergic, alpha/drug effects/*physiology; Stress/metabolism/physiopathology/veterinary; Time Factors; Tolazoline/administration & dosage/*pharmacology  
  Abstract Six ponies were used to investigate the effect of tolazoline antagonism of detomidine on physiological responses, behavior, epinephrine, norepinephrine, cortisol, glucose, and free fatty acids in awake ponies. Each pony had a catheter inserted into a jugular vein 1 hour before beginning the study. Awake ponies were administered detomidine (0.04 mg/kg intravenously [i.v.]) followed 20 minutes later by either tolazoline (4.0 mg/kg i.v.) or saline. Blood samples were drawn from the catheter 5 minutes before detomidine administration (baseline), 5 minutes after detomidine administration, 20 minutes before detomidine administration which was immediately before the administration of tolazoline or saline (time [T] = 0), and at 5, 30, and 60 minutes after injections of tolazoline or saline (T = 5, 30, and 60 minutes, respectively). Compared with heart rate at T = 0, tolazoline antagonism increased heart rate 45% at 5 minutes. There was no difference in heart rate between treatments at 30 minutes. Blood pressure remained stable after tolazoline, while it decreased over time after saline. Compared with concentrations at T = 0, tolazoline antagonism of detomidine in awake ponies resulted in a 55% increase in cortisol at 30 minutes and a 52% increase in glucose at 5 minutes. The change in free fatty acids was different for tolazoline and saline over time. Free fatty acids decreased after detomidine administration. Free fatty acids did not change after saline administration. After tolazoline administration, free fatty acids increased transiently. Tolazoline tended to decrease sedation and analgesia at 15 and 60 minutes postantagonism. Antagonism of detomidine-induced physiological and behavioral effects with tolazoline in awake ponies that were not experiencing pain appears to precipitate a stress response as measured by cortisol, glucose, and free fatty acids. If antagonism of an alpha-agonist is contemplated, the potential effect on hormones and metabolites should be considered.  
  Address Department of Small Animal Medicine and Surgery, Texas A&M University, College Station, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0161-3499 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:9123816 Approved no  
  Call Number refbase @ user @ Serial 96  
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Author Milgram, N.W.; Head, E.; Muggenburg, B.; Holowachuk, D.; Murphey, H.; Estrada, J.; Ikeda-Douglas, C.J.; Zicker, S.C.; Cotman, C.W. openurl 
  Title Landmark discrimination learning in the dog: effects of age, an antioxidant fortified food, and cognitive strategy Type Journal Article
  Year 2002 Publication Neuroscience and Biobehavioral Reviews Abbreviated Journal Neurosci Biobehav Rev  
  Volume (down) 26 Issue 6 Pages 679-695  
  Keywords Age Factors; Aging/*physiology; Analysis of Variance; Animals; Antioxidants/*pharmacology; Blood Chemical Analysis/methods; Cognition/*physiology; *Diet; Discrimination Learning/*drug effects/*physiology; Distance Perception/drug effects/physiology; Dogs/physiology; Female; Male; Psychomotor Performance/physiology; Retention (Psychology)/drug effects/physiology; Spatial Behavior/*drug effects/*physiology; Task Performance and Analysis; Time Factors; Vitamin E/blood  
  Abstract The landmark discrimination learning test can be used to assess the ability to utilize allocentric spatial information to locate targets. The present experiments examined the role of various factors on performance of a landmark discrimination learning task in beagle dogs. Experiments 1 and 2 looked at the effects of age and food composition. Experiments 3 and 4 were aimed at characterizing the cognitive strategies used in performance on this task and in long-term retention. Cognitively equivalent groups of old and young dogs were placed into either a test group maintained on food enriched with a broad-spectrum of antioxidants and mitochondrial cofactors, or a control group maintained on a complete and balanced food formulated for adult dogs. Following a wash-in period, the dogs were tested on a series of problems, in which reward was obtained when the animal responded selectively to the object closest to a thin wooden block, which served as a landmark. In Experiment 1, dogs were first trained to respond to a landmark placed directly on top of coaster, landmark 0 (L0). In the next phase of testing, the landmark was moved at successively greater distances (1, 4 or 10 cm) away from the reward object. Learning varied as a function of age group, food group, and task. The young dogs learned all of the tasks more quickly than the old dogs. The aged dogs on the enriched food learned L0 significantly more rapidly than aged dogs on control food. A higher proportion of dogs on the enriched food learned the task, when the distance was increased to 1cm. Experiment 2 showed that accuracy decreased with increased distance between the reward object and landmark, and this effect was greater in old animals. Experiment 3 showed stability of performance, despite using a novel landmark, and new locations, indicating that dogs learned the landmark concept. Experiment 4 found age impaired long-term retention of the landmark task. These results indicate that allocentric spatial learning is impaired in an age-dependent manner in dogs, and that age also affects performance when the distance between the landmark and target is increased. In addition, these results both support a role of oxidative damage in the development of age-associated cognitive dysfunction and indicate that short-term administration of a food enriched with supplemental antioxidants and mitochondrial cofactors can partially reverse the deleterious effects of aging on cognition.  
  Address Life Science Division, University of Toronto at Scarborough, 1265 Military Trail, Scarborough, Ont., Canada M1C 1A4. milgram@psych.utoronto.ca  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0149-7634 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12479842 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2806  
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Author Schmoldt, A.; Benthe, H.F.; Haberland, G. openurl 
  Title Digitoxin metabolism by rat liver microsomes Type Journal Article
  Year 1975 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol  
  Volume (down) 24 Issue 17 Pages 1639-1641  
  Keywords Animals; Chromatography, Thin Layer; Digitoxigenin/metabolism; Digitoxin/*metabolism; Hydroxylation; Male; Microsomes, Liver/*metabolism; NADP/metabolism; Rats; Time Factors  
  Abstract  
  Address  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0006-2952 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:10 Approved no  
  Call Number Admin @ knut @ Serial 20  
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Author Ulloa, A.; Gonzalez-Ceron, L.; Rodriguez, M.H. openurl 
  Title Host selection and gonotrophic cycle length of Anopheles punctimacula in southern Mexico Type Journal Article
  Year 2006 Publication Journal of the American Mosquito Control Association Abbreviated Journal J Am Mosq Control Assoc  
  Volume (down) 22 Issue 4 Pages 648-653  
  Keywords Animals; Anopheles/*physiology; Appetitive Behavior/*physiology; Cattle; Female; Horses; Humans; Insect Vectors/*physiology; Malaria/transmission; Mexico; Oviparity/*physiology; Seasons; Time Factors; Vitellogenesis/physiology  
  Abstract The host preference, survival rates, and length of the gonotrophic cycle of Anopheles punctimacula was investigated in southern Mexico. Mosquitoes were collected in 15-day separate experiments during the rainy and dry seasons. Daily changes in the parous-nulliparous ratio were recorded and the gonotrophic cycle length was estimated by a time series analysis. Anopheles punctimacula was most abundant during the dry season and preferred animals to humans. The daily survival rate in mosquitoes collected in animal traps was 0.96 (parity rate = 0.86; gonotrophic cycle = 4 days). The length of gonotrophic cycle of 4 days was estimated on the base of a high correlation coefficient value appearing every 4 days. The minimum time estimated for developing mature eggs after blood feeding was 72 h. The proportion of mosquitoes living enough to transmit Plasmodium vivax malaria during the dry season was 0.35.  
  Address Centro de Investigacion de Paludismo, Instituto Nacional de Salud Publica, Apartado Postal 537, Tapachula, Chiapas 30700, Mexico  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 8756-971X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:17304932 Approved no  
  Call Number Serial 1830  
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Author Fetterman, J.G. openurl 
  Title Dimensions of stimulus complexity Type Journal Article
  Year 1996 Publication Journal of Experimental Psychology. Animal Behavior Processes Abbreviated Journal J Exp Psychol Anim Behav Process  
  Volume (down) 22 Issue 1 Pages 3-18  
  Keywords Animals; *Behavior, Animal; Cognition; *Learning; Memory; Time Factors  
  Abstract Animal learning research has increasingly used complex stimuli that approximate natural objects, events, and locations, a trend that has accompanied a resurgence of interest in the role of cognitive factors in learning. Accounts of complex stimulus control have focused mainly on cognitive mechanisms and largely ignored the contribution of stimulus information to perception and memory for complex events. It is argued here that research on animal learning stands to benefit from a more detailed consideration of the stimulus and that James Gibson's stimulus-centered theory of perception serves as a useful framework for analyses of complex stimuli. Several issues in the field of animal learning and cognition are considered from the Gibsonian perspective on stimuli, including the fundamental problem of defining the effective stimulus.  
  Address Department of Psychology, Indiana University-Purdue University, Indianapolis 46202, USA  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0097-7403 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:8568494 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2782  
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Author Crowell-Davis, S.L.; Houpt, K.A. openurl 
  Title Coprophagy by foals: effect of age and possible functions Type Journal Article
  Year 1985 Publication Equine veterinary journal Abbreviated Journal Equine Vet J  
  Volume (down) 17 Issue 1 Pages 17-19  
  Keywords *Aging; Animals; *Coprophagia; Deoxycholic Acid/physiology; Female; Horse Diseases/*physiopathology; Horses; Humans; Male; Pheromones/physiology; Time Factors; Urination  
  Abstract In colts and fillies observed from birth to 24 weeks old, coprophagy occurred from Weeks 1 to 19. Its frequency was greatest during the first two months. Coprophagy was rarely observed in mares and stallions. Foals usually ate the faeces of their mother but were observed to eat their own and those of a stallion and another unrelated mare. Urination by the foal occurred before, during or after 26 per cent of the coprophagy incidents. It is hypothesised that foals may consume faeces in response to a maternal pheromone which signals the presence of deoxycholic acid or other acids which the foal may be deficient in and which it may require for gut immuno-competence myelination of the nervous system. Such a pheromone may also serve to accelerate growth and sexual maturation. Coprophagy may also provide nutrients and introduce normal bacterial flora to the gut.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:4038939 Approved no  
  Call Number refbase @ user @ Serial 55  
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Author Sufit, E.; Houpt, K.A.; Sweeting, M. openurl 
  Title Physiological stimuli of thirst and drinking patterns in ponies Type Journal Article
  Year 1985 Publication Equine veterinary journal Abbreviated Journal Equine Vet J  
  Volume (down) 17 Issue 1 Pages 12-16  
  Keywords Animals; Blood Proteins/analysis; Drinking Behavior/drug effects/*physiology; Furosemide/pharmacology; Horses/*physiology; Male; Osmolar Concentration; Osmotic Pressure; Sodium Chloride/pharmacology; Thirst/drug effects/*physiology; Time Factors; Water Deprivation/physiology  
  Abstract The stimuli that elicit thirst were studied in four ponies. Nineteen hours of water deprivation produced an increase in plasma protein from 67 +/- 0.1 g/litre to 72 +/- 2 g/litre, a mean (+/- se) increase in plasma sodium from 139 +/- 3 to 145 +/- 2 mmol/litre and an increase in plasma osmolality from 297 +/- 1 to 306 +/- 2 mosmol/litre. Undeprived ponies drank 1.5 +/- 0.9 kg/30 mins; 19 h deprived ponies drank 10.2 +/- 2.5 kg/30 mins and corrected the deficits in plasma protein, plasma sodium and plasma osmolality as well as compensating for the water they would have drunk during the deprivation period. In order to determine if an increase in plasma osmolality would stimulate thirst, 250 ml of 15 per cent sodium chloride was infused intravenously. The ponies drank when osmolality increased 3 per cent and when plasma sodium rose from 136 +/- 3 mmol/litre to 143 +/- 3 mmol/litre. Ponies infused with 15 per cent sodium chloride drank 2.9 +/- 0.7 kg; those infused with 0.9 per cent sodium chloride drank 0.7 +/- 0.5 kg. In order to determine if a decrease in plasma volume would stimulate thirst, ponies were injected with 1 or 2 mg/kg bodyweight (bwt) frusemide. Plasma protein rose from 68 +/- 2 g/litre pre-injection to 75 +/- 2 g/litre 1 h after 1 mg/kg bwt frusemide and to 81 +/- 1 g/litre 1 h after 2 mg/kg bwt frusemide.(ABSTRACT TRUNCATED AT 250 WORDS)  
  Address  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:3979367 Approved no  
  Call Number refbase @ user @ Serial 56  
Permanent link to this record
 

 
Author Alexander, F.; Nicholson, J.D. openurl 
  Title The blood and saliva clearances of phenobarbitone and pentobarbitone in the horse Type Journal Article
  Year 1968 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol  
  Volume (down) 17 Issue 2 Pages 203-210  
  Keywords Animals; Female; *Horses; Injections, Intravenous; Male; Metabolic Clearance Rate; Pentobarbital/blood/*metabolism; Phenobarbital/blood/*metabolism; Protein Binding; *Saliva; Time Factors  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0006-2952 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:5647047 Approved no  
  Call Number refbase @ user @ Serial 117  
Permanent link to this record
 

 
Author Steiner, M. openurl 
  Title Biomechanics of tendon healing Type Journal Article
  Year 1982 Publication Journal of Biomechanics Abbreviated Journal J Biomech  
  Volume (down) 15 Issue 12 Pages 951-958  
  Keywords Achilles Tendon/injuries; Animals; Biomechanics; Rats; Tendon Injuries/pathology/*physiopathology; Tensile Strength; Time Factors; *Wound Healing  
  Abstract The biomechanics of tendon healing was investigated with unsutured rat achilles tendons. After two, three, and four weeks of healing tensile parameters were assayed with a bone-muscle-tendon-bone preparation elongated to failure at a controlled physiological strain rate. In the third week of healing, stiffness, strength, and energy absorbing capacity all increased approximately 50%. These changes correlated with early fibroplasia. In the fourth week of healing, strength, energy absorbing capacity and elongation to failure all increased relatively more than stiffness. Histologically, larger fibers with better longitudinal alignment developed during this period. At the end of four weeks the tendon's strength was approximately 25% of normal. To summarize, the return of stiffness in a healing tendon preparation correlated with the presence of fibroplasia and the return of other tensile parameters was a function of the amount and organization of the fibroplasia.  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0021-9290 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:7166555 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4448  
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