| |
Records |
Links |
|
Author |
Turner, J.W.J.; Kirkpatrick, J.F. |
|
| |
Title |
Androgens, behaviour and fertility control in feral stallions |
Type |
Journal Article |
| |
Year |
1982 |
Publication |
Journal of reproduction and fertility. Supplement |
Abbreviated Journal |
J Reprod Fertil Suppl |
|
| |
Volume |
32 |
Issue |
|
Pages |
79-87 |
|
| |
Keywords |
Animals; Animals, Wild; Copulation/drug effects; Female; *Fertility/drug effects; Horses/*physiology; Male; Periodicity; Pregnancy; Seasons; *Sexual Behavior, Animal/drug effects; Sexual Maturation; Sperm Count; Sperm Motility/drug effects; Testosterone/*blood/pharmacology |
|
| |
Abstract |
This field study of feral stallions in Montana and Idaho examines and correlates the seasonal pattern of plasma androgens and specific sociosexual behaviour and reports the effect of a long-acting androgenic steroid on this behaviour and on fertility. Plasma testosterone was measured by competitive protein binding assay in samples obtained by jugular venepuncture from captured animals. In samples taken from 34 sexually mature stallions in 6 different months during the year, a definite seasonal pattern in testosterone was present, with a peak in May (3.04 +/- 0.63 ng/ml) and a nadir in December (1.55 +/- 0.34 ng/ml). Values were less than 2.0 ng/ml in non-breeding months and greater than 2.4 ng/ml in breeding months. Behavioural endpoints measured were (1) stallion scent marking in response to elimination by mares (elimination marking), (2) mounting and (3) copulation. The frequencies of each of these endpoints followed closely the seasonal pattern seen for plasma androgens. In the fertility study microcapsulated testosterone propionate (microTP) was administered i.m. to 10 harem stud stallions 3 months before the 1980 breeding season. In these stallions and in 10 control harem studs, the above behavioural endpoints were examined in the 1980 and 1981 breeding seasons, and foal counts were made in 1981. There were no direct inhibitory or stimulatory effects of microTP treatment on any of the behavioural endpoints in either year. In 1981 foals were produced in 87.5% of the control bands and 28.4% of the microTP-treated bands. These results indicate that microencapsulated testosterone propionate can provide effective fertility control in feral horses without causing significant alterations in sociosexual behaviour. |
|
| |
Address  |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0449-3087 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:6962905 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
138 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Henning, J.M.; Zentall, T.R. |
|
| |
Title |
Imitation, social facilitation, and the effects of ACTH 4-10 on rats' bar-pressing behavior |
Type |
Journal Article |
| |
Year |
1981 |
Publication |
The American journal of psychology |
Abbreviated Journal |
Am J Psychol |
|
| |
Volume |
94 |
Issue |
1 |
Pages |
125-134 |
|
| |
Keywords |
Adrenocorticotropic Hormone/*pharmacology; Animals; Conditioning, Operant/*drug effects; Dose-Response Relationship, Drug; Extinction, Psychological/drug effects; Imitative Behavior/*drug effects; Male; Peptide Fragments/*pharmacology; Rats; *Social Facilitation |
|
| |
Abstract |
The effects of ACTH 4-10 on rats' imitation learning was examined during the acquisition and extinction of a bar-press response for water reinforcement. Rats were exposed to either a bar-pressing conspecific (OB), an experimentally naive conspecific (ON), or an empty box (OE) during bar-press acquisition. In a factorial design, each rat was then exposed to one of the same three conditions during extinction. An 80 mcg dose of ACTH 4-10 was administered to half of the rats in each group prior to observation. Performance differences during acquisition were generally small, but significant performance differences during extinction were found. Social facilitation was indicated by the finding that rats extinguished in the presence of a conspecific exhibited significantly greater resistance to extinction than rats extinguished in the presence of an empty box. An imitation effect was also found. Rats that observed a bar-pressing conspecific during both acquisition and extinction (group OB-OB) showed significantly greater resistance top extinction than did groups OB-ON, CB-OE, or OE-OE. There were no significant effects of the hormone, however, relative to saline controls. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0002-9556 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:6263117 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
267 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Tobin, T.; Combie, J.D. |
|
| |
Title |
Performance testing in horses: a review of the role of simple behavioral models in the design of performance experiments |
Type |
Journal Article |
| |
Year |
1982 |
Publication |
Journal of Veterinary Pharmacology and Therapeutics |
Abbreviated Journal |
J Vet Pharmacol Ther |
|
| |
Volume |
5 |
Issue |
2 |
Pages |
105-118 |
|
| |
Keywords |
Analgesics, Opioid/pharmacology; Animals; Apomorphine/pharmacology; Behavior, Animal/*drug effects; Dose-Response Relationship, Drug; Fentanyl/pharmacology; Horses/*physiology; Methylphenidate/pharmacology; *Models, Biological; Motor Activity/drug effects |
|
| |
Abstract |
|
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0140-7783 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:6125601 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
1957 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Nelson, G.S. |
|
| |
Title |
Onchocerciasis |
Type |
Journal Article |
| |
Year |
1970 |
Publication |
Advances in Parasitology |
Abbreviated Journal |
Adv Parasitol |
|
| |
Volume |
8 |
Issue |
|
Pages |
173-224 |
|
| |
Keywords |
Africa; Animals; Anthelmintics/therapeutic use; Artiodactyla; Blindness/etiology; Cattle; Circadian Rhythm; Ddt; Diethylcarbamazine/therapeutic use; Diptera/anatomy & histology/growth & development; Dwarfism/etiology; Ecology; Eye/pathology; Feeding Behavior; Female; Geography; Haplorhini; Hernia, Femoral/etiology; Horses; Humans; Insect Vectors/growth & development; Larva/growth & development; Male; Onchocerca/classification/growth & development; *Onchocerciasis/diagnosis/drug therapy/epidemiology/immunology/pathology/prevention & control/veterinary; Primates; Serologic Tests; Skin/pathology; Skin Tests; Suramin/therapeutic use |
|
| |
Abstract |
|
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0065-308X |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:4997515 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2738 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Domjan, M. |
|
| |
Title |
Selective suppression of drinking during a limited period following aversive drug treatment in rats |
Type |
Journal Article |
| |
Year |
1977 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
|
| |
Volume |
3 |
Issue |
1 |
Pages |
66-76 |
|
| |
Keywords |
Animals; *Avoidance Learning; Awareness; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking Behavior/*drug effects; Lithium/*poisoning; Male; Osmolar Concentration; Rats; Saccharin/administration & dosage; *Taste; Time Factors |
|
| |
Abstract |
Administration of lithium chloride disrupted the intake of flavored solutions but not water in rats. This intake suppression was directly related to the amount of lithium administered (Experiment 1), occurred with both palatable and unpalatable novel saccharin solutions (Experiment 2), but was only observed if subjects were tested starting less than 75 min. after lithium treatment (Experiment 3). Twenty-five daily exposures to saccharin did not attenuate the effect (Experiment 4). However, in saccharin-reared and vinegar-reared rats, lithium did not disrupt consumption of the solutions these subjects had access to throughout life, even though suppressions of intake were observed when these subjects were tested with novel flavors (Experiment 5). The selective disruption of drinking is interpreted as a novelty-dependent sensitization reaction to the discomfort of aversive drug administration. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0097-7403 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:845544 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2788 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Mitchell, D.; Kirschbaum, E.H.; Perry, R.L. |
|
| |
Title |
Effects of neophobia and habituation on the poison-induced avoidance of exteroceptive stimuli in the rat |
Type |
Journal Article |
| |
Year |
1975 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
|
| |
Volume |
1 |
Issue |
1 |
Pages |
47-55 |
|
| |
Keywords |
Animals; Avoidance Learning/*drug effects; *Awareness; *Cognition; Conditioning, Operant; Feeding Behavior/drug effects; *Habituation, Psychophysiologic; Injections, Intraperitoneal; Lithium/administration & dosage/poisoning; Male; Rats; *Taste; Time Factors; *Visual Perception |
|
| |
Abstract |
Two experiments on the role of neophobia in poison-induced aversions to exteroceptive stimuli are reported. In Experiment 1, rats were given either 10 or 25 days of habituation to the test situation prior to conditioning. Those animals with the longer habituation period avoided a complex of novel exteroceptive stimuli while those with the shorter habituation period did not. In Experiment 2 rats initially avoided the more novel of two containers, but gradually came to eat equal amounts from both. A single pairing of toxicosis with consumption from either the novel or the familiar container reinstated the avoidance of the novel container in both cases. The results were discussed in terms of an interaction between habituation and conditioning procedures. It was suggested that previously reported differences between interoceptive and exteroceptive conditioning effects may have been influenced by the differential novelty of the two classes of stimuli in the test situation. It was further suggested that non-contingently poisoned control groups should routinely be included in poison avoidance conditioning studies. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0097-7403 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:1151289 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2791 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Pennisi, E. |
|
| |
Title |
Schizophrenia clues from monkeys |
Type |
|
| |
Year |
1997 |
Publication |
Science (New York, N.Y.) |
Abbreviated Journal |
Science |
|
| |
Volume |
277 |
Issue |
5328 |
Pages |
900 |
|
| |
Keywords |
Animals; Antipsychotic Agents/pharmacology; Behavior, Animal/drug effects; *Cercopithecus aethiops; Clozapine/pharmacology; Cognition/drug effects; *Disease Models, Animal; Dopamine/*metabolism; Excitatory Amino Acid Antagonists/pharmacology; Memory/drug effects; Phencyclidine/*pharmacology; Prefrontal Cortex/*metabolism; Schizophrenia/chemically induced/drug therapy/*metabolism; Schizophrenic Psychology |
|
| |
Abstract |
|
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0036-8075 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:9281070 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2844 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Dunn, M.F.; Branlant, G. |
|
| |
Title |
Roles of zinc ion and reduced coenzyme in horse liver alcohol dehydrogenase catalysis. The mechanism of aldehyde activation |
Type |
Journal Article |
| |
Year |
1975 |
Publication |
Biochemistry |
Abbreviated Journal |
Biochemistry |
|
| |
Volume |
14 |
Issue |
14 |
Pages |
3176-3182 |
|
| |
Keywords |
*Alcohol Oxidoreductases/metabolism; Aldehydes/*pharmacology; Animals; Binding Sites; Enzyme Activation/drug effects; Horses; Hydrogen-Ion Concentration; Kinetics; Liver/enzymology; *NAD/analogs & derivatives/pharmacology; Oxidation-Reduction; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Temperature; *Zinc/pharmacology |
|
| |
Abstract |
1,4,5,6-Tetrahydronicotinamide adenine dinucleotide (H2NADH) has been investigated as a reduced coenzyme analog in the reaction between trans-4-N,N-dimethylaminocinnamaldehyde (I) (lambdamax 398 nm, epsilonmax 3.15 X 10-4 M-minus 1 cm-minus 1) and the horse liver alcohol dehydrogenase-NADH complex. These equilibrium binding and temperature-jump kinetic studies establish the following. (i) Substitution of H2NADH for NADH limits reaction to the reversible formation of a new chromophoric species, lambdamax 468 nm, epsilonmax 5.8 x 10-4 M-minus 1 cm-minus 1. This chromophore is demonstrated to be structurally analogous to the transient intermediate formed during the reaction of I with the enzyme-NADH complex [Dunn, M. F., and Hutchison, J. S. (1973), Biochemistry 12, 4882]. (ii) The process of intermediate formation with the enzyme-NADH complex is independent of pH over the range 6.13-10.54. Although studies were limited to the pH range 5.98-8.72, a similar pH independence appears to hold for the H2NADH system. (iii) Within the ternary complex, I is bound within van der Waal's contact distance of the coenzyme nicotinamide ring. (iv) Formation of the transient intermediate does not involve covalent modification of coenzyme. Based on these findings, we conclude that zinc ion has a Lewis acid function in facilitating the chemical activation of the aldehyde carbonyl for reduction, and that reduced coenzyme plays a noncovalent effector role in this substrate activating step. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0006-2960 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:238585 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
3817 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Wilson, M.T.; Silvestrini, M.C.; Morpurgo, L.; Brunori, M. |
|
| |
Title |
Electron transfer kinetics between Rhus vernicifera stellacyanin and cytochrome c (horse heart cytochrome c and Pseudomonas cytochrome c551) |
Type |
Journal Article |
| |
Year |
1979 |
Publication |
Journal of Inorganic Biochemistry |
Abbreviated Journal |
J Inorg Biochem |
|
| |
Volume |
11 |
Issue |
2 |
Pages |
95-100 |
|
| |
Keywords |
Animals; Copper; Cytochrome c Group/*metabolism; Electron Transport; Kinetics; Metalloproteins/*metabolism; Plant Proteins/*metabolism; *Plants, Toxic; Pseudomonas aeruginosa/*metabolism; Toxicodendron/*metabolism |
|
| |
Abstract |
The electron transfer reactions between Rhus vernicifera stellacyanin and either horse heart cytochrome c or Pseudomonas aeruginosa cytochrome c551 were investigated by rapid reaction techniques. The time course of electron transfer is monophasic under all conditions, and thus consistent with a simple formulation of the reaction. Both stopped-flow and temperature-jump experiments yield equilibrium constants in reasonable agreement with values calculated from the redox potentials. The differences in reaction rate between the two cytochromes and stellacyanin are discussed in terms of the Marcus theory. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0162-0134 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:228006 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
3879 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Tsong, T.Y. |
|
| |
Title |
Conformational relaxations of urea- and guanidine hydrochloride-unfolded ferricytochrome c |
Type |
Journal Article |
| |
Year |
1977 |
Publication |
The Journal of Biological Chemistry |
Abbreviated Journal |
J Biol Chem |
|
| |
Volume |
252 |
Issue |
24 |
Pages |
8778-8780 |
|
| |
Keywords |
*Cytochrome c Group; Guanidines/*pharmacology; Protein Conformation/drug effects; Spectrometry, Fluorescence; Urea/*pharmacology |
|
| |
Abstract |
Several recent studies of protein the unfolded proteins. In urea- and guanidine HCl-unfolded ferricytochrome c (horse heart), an acid-induced spin state transformation of the heme group has been detected by the heme absorptions, Trp-59 fluorescence, and the intrinsic viscosity of protein. Kinetics of this second conformational transition, by the temperature jump and stopped flow methods, are complex. One rapid reaction (tau1), pH-independent, occurs in a 50-mus range; the second reaction (tau2), in a 1-ms range, depends linearly upon pH and is faster at the alkaline side; a third reaction (tau3), in a 1-s range, shows a sigmoidal transition at pH 5.1 and is faster at the acidic side. The results are consistent with a kinetic scheme which involves protein conformational changes in the transformation of the heme coordination state. The kinetics, along with previous equilibrium studies, indicate that ligand or charge interactions within a protein molecule are not completely prohibited even in strongly denaturing conditions, such as in high concentrations of urea and guanidine HCl. Thus, local structures of peptide chain associated with these interactions can exist in the unfolded protein. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0021-9258 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:200618 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
3882 |
|
| Permanent link to this record |
