| Records |
| Author |
Bannasch, D.; Rinaldo, C.; Millon, L.; Latson, K.; Spangler, T.; Hubberty, S.; Galuppo, L.; Lowenstine, L. |
| Title |
SRY negative 64,XX intersex phenotype in an American saddlebred horse |
Type |
Journal Article |
| Year |
2007 |
Publication |
Veterinary Journal (London, England : 1997) |
Abbreviated Journal |
Vet J |
| Volume |
173 |
Issue |
2 |
Pages |
437-439 |
| Keywords |
Animals; Female; Genitalia/abnormalities; Hermaphroditism/*veterinary; Horse Diseases/*diagnosis/genetics; Horses/*genetics/*physiology; Karyotyping; Phenotype; Sex Differentiation; Sex Differentiation Disorders/diagnosis/veterinary; Sex-Determining Region Y Protein/genetics/*metabolism |
| Abstract |
A female American saddlebred horse was presented for surgical correction of a possible pseudohermaphrodite condition. The horse had abnormal external genitalia and exhibited stallion-like behaviour. No evidence of uterine or ovarian tissue was identified on laparoscopic examination, but hypoplastic testicular-like tissue was removed, although this was found to contain no spermatogonia upon histopathological examination. A karyotype was performed and showed the normal chromosomal complement for a female horse (64,XX). Polymerase chain reaction to detect the SRY gene was negative in peripheral blood as well as the testicular-like tissue. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse. |
| Address |
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. dlbannasch@ucdavis.edu |
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English |
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Series Issue |
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Edition |
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| ISSN |
1090-0233 |
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| Notes |
PMID:16386440 |
Approved |
no |
| Call Number |
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Serial |
1882 |
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| Author |
Breen, M.; Downs, P.; Irvin, Z.; Bell, K. |
| Title |
Intrageneric amplification of horse microsatellite markers with emphasis on the Przewalski's horse (E. przewalskii) |
Type |
Journal Article |
| Year |
1994 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
| Volume |
25 |
Issue |
6 |
Pages |
401-405 |
| Keywords |
Animals; DNA, Satellite/*genetics; *Gene Amplification; Gene Frequency; *Genetic Markers; Heterozygote; Horses/*genetics; Species Specificity |
| Abstract |
Primer sequences flanking 13 microsatellite loci isolated from the domestic horse (E. caballus) were successfully used to amplify homologous loci in the Przewalski's horse (E. przewalskii). The results demonstrate that the level of polymorphism at all 13 loci in the Przewalski's horse was comparable to that in the domestic horse and the overall exclusion probability in the Przewalski's horse was calculated to be 0.9994. The results suggest that it should be possible to use E. caballus-derived microsatellite markers to provide parentage verification and additional valuable information to the captive management of E. przewalskii. The ability to amplify corresponding loci in the remaining five species of the genus was also confirmed, illustrating the general application of markers isolated from the domestic horse to the evaluation of polymorphism in the other six species of the genus. |
| Address |
Australian Equine Blood Typing Research Laboratory, University of Queensland, St Lucia |
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English |
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| ISSN |
0268-9146 |
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Conference |
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| Notes |
PMID:7695120 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2246 |
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| Author |
Hintz, R.L. |
| Title |
Genetics of performance in the horse |
Type |
Journal Article |
| Year |
1980 |
Publication |
Journal of Animal Science |
Abbreviated Journal |
J. Anim Sci. |
| Volume |
51 |
Issue |
3 |
Pages |
582-594 |
| Keywords |
Animals; Exertion; Horses/*genetics/physiology; Sports |
| Abstract |
Criteria used to measure performance, environmental factors that influence performance and estimates of heritability are needed to estimate genetic differences. Published heritability estimates of various measures of performance in the horse are summarized. The average heritability estimates of pulling ability and cutting ability are .25 and .04, respectively. Heritability estimates are .18, .19 and .17 for log of earnings from jumping, 3-day event and dressage performance, respectively. Heritability estimates of performance rates, log of earnings, earnings, handicap weight, best handicap weight, time and best time for the Thoroughbred are .55, .49, .09, .49, .33, .15 and .23, respectively. Heritability estimates of log of earnings, earnings, time and best time for the trotter are .41, .20, .32, and .25, respectively. The heritability estimate of best time for the pacer is .23. The effectiveness of selection will depend on which performance trait is to be improved. |
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English |
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| ISSN |
0021-8812 |
ISBN |
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| Notes |
PMID:7440446 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
3758 |
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| Author |
Ishida, N.; Hirano, T.; Mukoyama, H. |
| Title |
Detection of aberrant alleles in the D-loop region of equine mitochondrial DNA by single-strand conformation polymorphism (SSCP) analysis |
Type |
Journal Article |
| Year |
1994 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
| Volume |
25 |
Issue |
4 |
Pages |
287 |
| Keywords |
*Alleles; Animals; Base Sequence; *DNA, Mitochondrial; DNA, Single-Stranded/genetics; Female; Gene Frequency; Genomic Imprinting; Horses/*genetics; Male; Molecular Sequence Data; Pedigree; *Polymorphism, Genetic |
| Abstract |
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| Address |
Laboratory of Molecular and Cellular Biology, Japan Racing Association, Tokyo |
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| Language |
English |
Summary Language |
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Original Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0268-9146 |
ISBN |
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Conference |
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| Notes |
PMID:7985852 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2213 |
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| Author |
Ishida, N.; Oyunsuren, T.; Mashima, S.; Mukoyama, H.; Saitou, N. |
| Title |
Mitochondrial DNA sequences of various species of the genus Equus with special reference to the phylogenetic relationship between Przewalskii's wild horse and domestic horse |
Type |
Journal Article |
| Year |
1995 |
Publication |
Journal of Molecular Evolution |
Abbreviated Journal |
J Mol Evol |
| Volume |
41 |
Issue |
2 |
Pages |
180-188 |
| Keywords |
Animals; Base Sequence; Chromosomes; Conserved Sequence/genetics; DNA, Mitochondrial/*genetics; Evolution; Genetic Variation/*genetics; Horses/*genetics; Molecular Sequence Data; *Phylogeny; RNA, Transfer, Pro/genetics; Sequence Alignment; Sequence Analysis, DNA |
| Abstract |
The noncoding region between tRNAPro and the large conserved sequence block is the most variable region in the mammalian mitochondrial DNA D-loop region. This variable region (ca. 270 bp) of four species of Equus, including Mongolian and Japanese native domestic horses as well as Przewalskii's (or Mongolian) wild horse, were sequenced. These data were compared with our recently published Thoroughbred horse mitochondrial DNA sequences. The evolutionary rate of this region among the four species of Equus was estimated to be 2-4 x 10(-8) per site per year. Phylogenetic trees of Equus species demonstrate that Przewalskii's wild horse is within the genetic variation among the domestic horse. This suggests that the chromosome number change (probably increase) of the Przewalskii's wild horse occurred rather recently. |
| Address |
Laboratory of Molecular and Cellular Biology, Japan Racing Association, Tokyo |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0022-2844 |
ISBN |
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Medium |
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| Notes |
PMID:7666447 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5042 |
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| Author |
Momozawa, Y.; Takeuchi, Y.; Tozaki, T.; Kikusui, T.; Hasegawa, T.; Raudsepp, T.; Chowdhary, B.P.; Kusunose, R.; Mori, Y. |
| Title |
SNP detection and radiation hybrid mapping in horses of nine candidate genes for temperament |
Type |
Journal Article |
| Year |
2007 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
| Volume |
38 |
Issue |
1 |
Pages |
81-83 |
| Keywords |
Animals; *Behavior, Animal; Breeding; Horses/*genetics/physiology; *Polymorphism, Single Nucleotide; Radiation Hybrid Mapping; *Temperament |
| Abstract |
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| Address |
Laboratory of Veterinary Ethology, The University of Tokyo, Tokyo 113-8657, Japan |
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English |
Summary Language |
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Edition |
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| ISSN |
0268-9146 |
ISBN |
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Conference |
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| Notes |
PMID:17257195 |
Approved |
no |
| Call Number |
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Serial |
1834 |
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| Author |
Oakenfull, E.A.; Ryder, O.A. |
| Title |
Mitochondrial control region and 12S rRNA variation in Przewalski's horse (Equus przewalskii) |
Type |
Journal Article |
| Year |
1998 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
| Volume |
29 |
Issue |
6 |
Pages |
456-459 |
| Keywords |
Animals; DNA, Mitochondrial/*genetics; Female; *Genetic Variation; Horses/*genetics; Male; Pedigree; RNA, Ribosomal/*genetics |
| Abstract |
Variation in the control region and the 12S rRNA gene of all surviving mitochondrial lineages of Przewalski's horse was investigated. Variation is low despite the present day population being descended from 13 individuals probably representing animals from three different regions of its range. Phylogenetic comparison of these sequences, with sequences for the domestic horse, does not resolve the ancestral status of either horse. |
| Address |
Center for Reproduction of Endangered Species, Zoological Society of San Diego, CA 92112, USA |
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English |
Summary Language |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0268-9146 |
ISBN |
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Conference |
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| Notes |
PMID:9883508 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5040 |
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| Author |
Ricard, A.; Chanu, I. |
| Title |
Genetic parameters of eventing horse competition in France |
Type |
Journal Article |
| Year |
2001 |
Publication |
Genetics, Selection, Evolution. : GSE |
Abbreviated Journal |
Genet Sel Evol |
| Volume |
33 |
Issue |
2 |
Pages |
175-190 |
| Keywords |
Animals; Behavior, Animal; Female; France; Genotype; Horses/*genetics; Male; Physical Conditioning, Animal; Selection (Genetics); *Sports; Stereotyped Behavior |
| Abstract |
Genetic parameters of eventing horse competitions were estimated. About 13 000 horses, 30 000 annual results during 17 years and 110 000 starts in eventing competitions during 8 years were recorded. The measures of performance were logarithmic transformations of annual earnings, annual earnings per start, and annual earnings per place, and underlying variables responsible for ranks in each competition. Heritabilities were low (0.11 / 0.17 for annual results, 0.07 for ranks). Genetic correlations between criteria were high (greater than 0.90) except between ranks and earnings per place (0.58) or per start (0.67). Genetic correlations between ages (from 5 to 10 years old) were also high (more than 0.85) and allow selection on early performances. The genetic correlation between the results in different levels of competition (high/international and low/amateur) was near 1. Genetic correlations of eventing with other disciplines, which included partial aptitude needed for eventing, were very low for steeplechase races (0.18) and moderate with sport: jumping (0.45), dressage (0.58). The results suggest that selection on jumping performance will lead to some positive correlated response for eventing performance, but much more response could be obtained if a specific breeding objective and selection criteria were developed for eventing. |
| Address |
Institut national de la recherche agronomique, Station de genetique quantitative et appliquee, 78352 Jouy-en-Josas Cedex, France. ugenata@dga.inra.fr |
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English |
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Series Issue |
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Edition |
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| ISSN |
0999-193X |
ISBN |
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| Notes |
PMID:11333833 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
3728 |
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| Author |
Stock, K.F.; Distl, O. |
| Title |
Evaluation of expected response to selection for orthopedic health and performance traits in Hanoverian Warmblood horses |
Type |
Journal Article |
| Year |
2005 |
Publication |
American Journal of Veterinary Research |
Abbreviated Journal |
Am J Vet Res |
| Volume |
66 |
Issue |
8 |
Pages |
1371-1379 |
| Keywords |
Animals; Bone Diseases/genetics/*veterinary; *Breeding; Genetic Predisposition to Disease; Horse Diseases/*genetics; Horses/*genetics; Joint Diseases/genetics/*veterinary; Selection (Genetics) |
| Abstract |
OBJECTIVE: To determine whether selection schemes accounting for orthopedic health traits were compatible with breeding progress in performance parameters in Hanoverian Warmblood horses. ANIMALS: 5,928 horses. PROCEDURE: Relative breeding values (RBVs) were predicted for osseous fragments in fetlock (metacarpo- and metatarsophalangeal) and tarsal joints, deforming arthropathy in tarsal joints, and pathologic changes in distal sesamoid bones. Selection schemes were developed on the basis of total indices for radiographic findings (TIR), dressage (TID), and jumping (TIJ). Response to selection was traced over 2 generations of horses for dressage and jumping ability and all-purpose breeding. Development of mean RBVs and mean total indices in sires and prevalences of orthopedic health traits in their offspring were used to assess response to selection. RESULTS: Giving equal weight toTIR andTID, TIJ, or a combined index of 60% TID and 40% TIJ, 43% to 53% of paternal grandsires and 70% to 82% of descending sires passed selection. In each case, RBVs and total indices increased by as much as 9% in selected sires, when compared with all sires, and prevalences of orthopedic health traits in offspring of selected sires decreased relatively by as much as 16%. When selection was exclusively based on TID, TIJ, or TID and TIJ, percentages of selected sires were 44% to 66% in the first and 73% to 84% in the second generation and TID and TIJ increased by 9% to 10% and 19% to 23%, respectively. CONCLUSIONS AND CLINICAL RELEVANCE: Compared with exclusively performance-based selection, percentages of selected sires changed slightly and breeding progress in TID, TIJ, or TID and TIJ was only slightly decreased; however, prevalences of orthopedic health traits decreased in offspring of TIR-selected sires. |
| Address |
Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover (Foundation), Bunteweg 17p, 30559 Hannover, Germany |
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English |
Summary Language |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0002-9645 |
ISBN |
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| Notes |
PMID:16173480 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
3713 |
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