Records |
Author |
Baum, M.J. |
Title |
Mammalian animal models of psychosexual differentiation: when is 'translation' to the human situation possible? |
Type |
Journal Article |
Year |
2006 |
Publication |
Hormones and Behavior |
Abbreviated Journal |
Horm Behav |
Volume |
50 |
Issue |
4 |
Pages |
579-588 |
Keywords |
Animals; Estradiol/*physiology; Female; *Gender Identity; Humans; Hypothalamus/anatomy & histology/physiology; Male; Models, Animal; Sexual Behavior/physiology/psychology; Sexual Behavior, Animal/*physiology; Testosterone/*physiology |
Abstract |
Clinical investigators have been forced primarily to use experiments of nature (e.g., cloacal exstrophy; androgen insensitivity, congenital adrenal hyperplasia) to assess the contribution of fetal sex hormone exposure to the development of male- and female-typical profiles of gender identity and role behavior as well as sexual orientation. In this review, I summarize the results of numerous correlative as well as mechanistic animal experiments that shed significant light on general neuroendocrine mechanisms controlling the differentiation of neural circuits controlling sexual partner preference (sexual orientation) in mammalian species including man. I also argue, however, that results of animal studies can, at best, provide only indirect insights into the neuroendocrine determinants of human gender identity and role behaviors. |
Address |
Department of Biology, Boston University, 5 Cummington Sreet, Boston, MA 02215, USA. baum@bu.edu |
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Language |
English |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0018-506X |
ISBN |
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Medium |
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Conference |
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Notes |
PMID:16876166 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
4190 |
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Author |
Enileeva, N.K. |
Title |
[Ecological characteristics of horse stomach botflies in Uzbekistan] |
Type |
Journal Article |
Year |
1987 |
Publication |
Parazitologiia |
Abbreviated Journal |
Parazitologiia |
Volume |
21 |
Issue |
4 |
Pages |
577-579 |
Keywords |
Animals; Diptera/*physiology; Ecology; Female; Flight, Animal; Horses/*parasitology; Larva/physiology; Male; Population Dynamics; Uzbekistan |
Abstract |
The paper describes the flight periods and dynamics of abundance of horse botflies, life span of females and males, effect of environmental factors on the activity of flies and their behaviour, potential fecundity of different species of botflies, duration of embryonal development, preservation of viability of larvae in egg membranes, localization of different stages of botflies in the host, and methods of their control. |
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Language |
Russian |
Summary Language |
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Original Title |
Ekologicheskie osobennosti zheludochnykh ovodov loshadei v Uzbekistane |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0031-1847 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:2958767 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2680 |
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Author |
Waters, A.J.; Nicol, C.J.; French, N.P. |
Title |
Factors influencing the development of stereotypic and redirected behaviours in young horses: findings of a four year prospective epidemiological study |
Type |
Journal Article |
Year |
2002 |
Publication |
Equine veterinary journal |
Abbreviated Journal |
Equine Vet J |
Volume |
34 |
Issue |
6 |
Pages |
572-579 |
Keywords |
Age Factors; Animal Husbandry/*methods; Animal Welfare; Animals; *Behavior, Animal; Female; Horse Diseases/epidemiology/prevention & control/*psychology; Horses; Housing, Animal; Longitudinal Studies; Male; Prevalence; Prospective Studies; Risk Factors; *Stereotyped Behavior; Weaning |
Abstract |
Stereotypies are invariant and repetitive behaviour patterns that seemingly have no function, which tend to develop in captive animals faced with insoluble problems and may be indicative of reduced welfare. A 4 year prospective study of the factors influencing the development of stereotypic and redirected behaviours (abnormal behaviour) in a population of 225 young Thoroughbred and part-Thoroughbred horses was conducted between 1995 and 1999. Abnormal behaviour affected 34.7% of the population. Multivariable analysis showed that foals of low- or middle-ranking mares were less likely to develop abnormal behaviour than foals of dominant mares (rate ratio (RR) 0.23, P<0.01; RR 0.48, P<0.01, respectively). Weaning by confinement in a stable or barn was associated with an increased rate of development of abnormal behaviour, compared with paddock-weaning (RR 2.19, P<0.05), and housing in barns, rather than at grass after weaning, was associated with a further increase (RR 2.54, P<0.01). Specific stereotypic and redirected behaviours were then considered as separate outcomes. Crib-biting was initiated by 10.5% of horses at median age 20 weeks, weaving by 4.6% of horses at median age 60 weeks, box-walking by 2.3% of horses at median age 64 weeks and wood-chewing by 30.3% of horses at median age 30 weeks. Wood-chewing developed at a lower rate in horses born to subordinate or mid-ranking mares than in horses born to dominant mares (RR 0.29, P<0.01; RR 0.41, P<0.01, respectively), and at a higher rate in horses kept in barns or stables rather than at grass after weaning (RR 4.49, P<0.001; RR 1A6, P<0.001, respectively). Feeding concentrates after weaning was associated with a 4-fold increase in the rate of development of crib-biting (RR 4.12, P = 0.02). The results of this study support the idea that simple changes in feeding, housing and weaning practices could substantially lower the incidence of abnormal behaviour in young horses. |
Address |
University of Bristol, Department of Clinical Veterinary Science, Langford, Bristol, UK |
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Language |
English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0425-1644 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:12357996 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
84 |
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Author |
Ikeda, M.; Patterson, K.; Graham, K.S.; Ralph, M.A.L.; Hodges, J.R. |
Title |
A horse of a different colour: do patients with semantic dementia recognise different versions of the same object as the same? |
Type |
Journal Article |
Year |
2006 |
Publication |
Neuropsychologia |
Abbreviated Journal |
Neuropsychologia |
Volume |
44 |
Issue |
4 |
Pages |
566-575 |
Keywords |
Adult; Aged; Anomia/diagnosis/psychology; Atrophy; *Attention; Color Perception; Dementia/*diagnosis/psychology; *Discrimination Learning; Dominance, Cerebral; Female; Humans; Male; *Memory, Short-Term; Middle Aged; Neuropsychological Tests; Orientation; *Pattern Recognition, Visual; Reference Values; Retention (Psychology); Semantics; Size Perception; Temporal Lobe/pathology |
Abstract |
Ten patients with semantic dementia resulting from bilateral anterior temporal lobe atrophy, and 10 matched controls, were tested on an object recognition task in which they were invited to choose (from a four-item array) the picture representing “the same thing” as an object picture that they had just inspected and attempted to name. The target in the response array was never physically identical to the studied picture but differed from it – in the various conditions – in size, angle of view, colour or exemplar (e.g. a different breed of dog). In one test block for each patient, the response array was presented immediately after the studied picture was removed; in another block, a 2 min filled delay was inserted between study and test. The patients performed relatively well when the studied object and target response differed only in the size of the picture on the page, but were significantly impaired as a group in the other three type-of-change conditions, even with no delay between study and test. The five patients whose structural brain imaging revealed major right-temporal atrophy were more impaired overall, and also more affected by the 2 min delay, than the five patients with an asymmetric pattern characterised by predominant left-sided atrophy. These results are interpreted in terms of a hypothesis that successful classification of an object token as an object type is not a pre-semantic ability but rather results from interaction of perceptual and conceptual processing. |
Address |
Department of Neuropsychiatry, Ehime University School of Medicine, Shitsukawa, Toon City, Ehime 791-0295, Japan. mikeda@m.ehime-u.ac.jp |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0028-3932 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:16115656 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
4059 |
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Author |
de Waal, F.B.; Berger, M.L. |
Title |
Payment for labour in monkeys |
Type |
Journal Article |
Year |
2000 |
Publication |
Nature |
Abbreviated Journal |
Nature |
Volume |
404 |
Issue |
6778 |
Pages |
563 |
Keywords |
Animals; Cebus/*physiology; *Cooperative Behavior; Evolution; *Feeding Behavior; Female; Male; Reward |
Abstract |
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Address |
Living Links, Yerkes Regional Primate Research Center, and Department of Psychology, Emory University, Atlanta, Georgia 30329, USA. dewaal@emory.edu |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0028-0836 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:10766228 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
190 |
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Author |
Crowell-Davis, S.L.; Houpt, K.A. |
Title |
Maternal behavior |
Type |
Journal Article |
Year |
1986 |
Publication |
The Veterinary clinics of North America. Equine practice |
Abbreviated Journal |
Vet Clin North Am Equine Pract |
Volume |
2 |
Issue |
3 |
Pages |
557-571 |
Keywords |
Aggression; Animals; Animals, Wild; Female; *Horses; Lactation; *Maternal Behavior; Pregnancy; *Pregnancy, Animal; Rejection (Psychology) |
Abstract |
Parturition in mares is rapid and is followed by a brief period of sensitivity to imprinting on a foal. There is large individual variation in normal maternal style, but normal mothers actively defend their foal, remain near the foal when it is sleeping, tolerate or assist nursing, and do not injure their own foal. Disturbance of a mare and foal during the early imprinting period can predispose a mare to rejection of her foal; therefore, it should be avoided. There are a variety of forms of foal rejection and numerous etiologies. Therefore, each case should be evaluated individually. |
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English |
Summary Language |
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Original Title |
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Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
0749-0739 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:3492245 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
49 |
Permanent link to this record |
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Author |
Nicol, C.J.; Adachi, M.; Akiyama, T.E.; Gonzalez, F.J. |
Title |
PPARgamma in endothelial cells influences high fat diet-induced hypertension |
Type |
Journal Article |
Year |
2005 |
Publication |
American journal of hypertension : journal of the American Society of Hypertension |
Abbreviated Journal |
Am J Hypertens |
Volume |
18 |
Issue |
4 Pt 1 |
Pages |
549-556 |
Keywords |
Administration, Oral; Animals; Antihypertensive Agents/pharmacology; Blood Pressure/drug effects; Diabetes Mellitus, Type 2/physiopathology; Dietary Fats/*administration & dosage/pharmacology; Dose-Response Relationship, Drug; Endothelial Cells/*metabolism; Female; Heart Rate/drug effects; Hypertension/*etiology; Ligands; Male; Mice; Mice, Knockout; PPAR gamma/*metabolism; Sodium Chloride/administration & dosage/pharmacology; Thiazolidinediones/pharmacology |
Abstract |
BACKGROUND: Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands improve human hypertension. However, the mechanism and site of this effect remains unknown, confounded by PPARgamma expression in many cell types, including endothelial cells (ECs). METHODS: To evaluate the vascular role of PPARgamma we used a conditional null mouse model. Specific disruption of PPARgamma in ECs was created by crossing Tie2-Cre+ transgenic (T2T+) and PPARgamma-floxed (fl/fl) mice to generate PPARgamma (fl/fl)T2T+ (PPARgamma E-null) mice. Conscious 8- to 12-week-old congenic PPARgamma (fl/fl)Cre- (wild type) and PPARgamma E-null mice were examined for changes in systolic blood pressure (BP) and heart rate (HR), untreated, after 2 months of salt-loading (drinking water), and after treatment for 3 months with high fat (HF) diet alone or supplemented during the last 2 weeks with rosiglitazone (3 mg/kg/d). RESULTS: Untreated PPARgamma E-nulls were phenotypically indistinguishable from wild-type littermates. However, compared to similarly treated wild types, HF-treated PPARgamma E-nulls had significantly elevated systolic BP not seen after normal diet or salt-loading. Despite sex-dependent baseline differences, salt-loaded and HF-treated PPARgamma E-nulls of either sex had significantly elevated HR versus wild types. Interestingly, rosiglitazone improved serum insulin levels, but not HF diet-induced hypertension, in PPARgamma E-null mice. CONCLUSIONS: These results suggest that PPARgamma in ECs not only is an important regulator of hypertension and HR under stressed conditions mimicking those arising in type 2 diabetics, but also mediates the antihypertensive effects of rosiglitazone. These data add evidence supporting a beneficial role for PPARgamma-specific ligands in the treatment of hypertension, and suggest therapeutic strategies targeting ECs may prove useful. |
Address |
Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA |
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English |
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Edition |
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ISSN |
0895-7061 |
ISBN |
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Medium |
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Area |
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Conference |
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Notes |
PMID:15831367 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
69 |
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Author |
Wilkins, L.J.; Brown, S.N.; Zimmerman, P.H.; Leeb, C.; Nicol, C.J. |
Title |
Investigation of palpation as a method for determining the prevalence of keel and furculum damage in laying hens |
Type |
Journal Article |
Year |
2004 |
Publication |
The Veterinary record |
Abbreviated Journal |
Vet. Rec. |
Volume |
155 |
Issue |
18 |
Pages |
547-549 |
Keywords |
Animal Husbandry/methods; Animal Welfare; Animals; Bone and Bones/*injuries; Chickens/*injuries; Female; Fractures, Bone/diagnosis/epidemiology/*veterinary; Great Britain/epidemiology; Housing, Animal/standards; Oviposition; Palpation/methods/*veterinary; Poultry Diseases/*diagnosis/epidemiology; Prevalence; Sensitivity and Specificity |
Abstract |
Old breaks of the keel and furculum were identified by palpation in 500 end-of-lay hens from 10 flocks housed in free-range and barn systems, and the results were compared with the results obtained by a full dissection and inspection. The method was considered to be sufficiently precise to be used as a diagnostic tool although people using it would need to be trained. The results obtained by dissection indicated that 50 to 78 per cent of the birds in the flocks had breaks of the furculum and keel, but no other breaks of bones were detected. |
Address |
Department of Clinical Veterinary Science, University of Bristol, Bristol BS40 5DU |
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English |
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Series Volume |
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Edition |
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ISSN |
0042-4900 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:15559420 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
70 |
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Author |
Boice, R. |
Title |
Behavioral comparability of wild and domesticated rats |
Type |
Journal Article |
Year |
1981 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
Volume |
11 |
Issue |
5 |
Pages |
545-553 |
Keywords |
Animals; *Behavior, Animal; Female; Genetics, Behavioral; Intelligence; Learning; Male; Rats/*genetics |
Abstract |
The oft-repeated concern for the lack of behavioral comparability of domestic rats with wild forms of Rattus norvegicus is unfounded. Laboratory rats appear to show the potential for all wild-type behaviors, including the most dramatic social postures. Moreover, domestics are capable of assuming a feral existence without difficulty, one where they readily behave in a fashion indistinguishable from wild rats. The one behavioral difference that is clearly established concerns performance in laboratory learning paradigms. The superiority of domestics in these laboratory tasks speaks more to quieting the concerns of degeneracy theorists than to problems of using domestic Norway rats as subjects representative of their species. |
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ISSN |
0001-8244 |
ISBN |
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Notes |
PMID:7325955 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
4144 |
Permanent link to this record |
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Author |
Zentall, S.S.; Zentall, T.R.; Barack, R.C. |
Title |
Distraction as a function of within-task stimulation for hyperactive and normal children |
Type |
Journal Article |
Year |
1978 |
Publication |
Journal of learning disabilities |
Abbreviated Journal |
J Learn Disabil |
Volume |
11 |
Issue |
9 |
Pages |
540-548 |
Keywords |
*Attention; Child; Child, Preschool; Color Perception; Female; Humans; Hyperkinesis/*psychology; Male; Motor Skills; *Task Performance and Analysis; Visual Perception |
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0022-2194 |
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Notes |
PMID:731119 |
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no |
Call Number |
refbase @ user @ |
Serial |
270 |
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