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Author Sinclair, M.; Buhrmann, G.; Gummow, B. openurl 
  Title An epidemiological investigation of the African horsesickness outbreak in the Western Cape Province of South Africa in 2004 and its relevance to the current equine export protocol Type Journal Article
  Year 2006 Publication Journal of the South African Veterinary Association Abbreviated Journal (up) J S Afr Vet Assoc  
  Volume 77 Issue 4 Pages 191-196  
  Keywords African Horse Sickness/diagnosis/*epidemiology; African horse sickness virus/*isolation & purification; Animals; Ceratopogonidae/virology; Diagnosis, Differential; Disease Outbreaks/*veterinary; Female; Horses; Insect Vectors/virology; Male; Prevalence; Retrospective Studies; Sentinel Surveillance; South Africa/epidemiology; Viral Vaccines/administration & dosage  
  Abstract African Horsesickness (AHS) is a controlled disease in South Africa. The country is divided into an infected area and a control area. An outbreak of AHS in the control area can result in a ban of exports for at least 2 years. A retrospective epidemiological study was carried out on data collected during the 2004 AHS outbreak in the surveillance zone of the AHS control area in the Western Cape Province. The objective of this study was to describe the 2004 outbreak and compare it with the 1999 AHS outbreak in the same area. As part of the investigation, a questionnaire survey was conducted in the 30 km radius surrounding the index case. Spatial, temporal and population patterns for the outbreak are described. The investigation found that the outbreak occurred before any significant rainfall and that the main AHS vector (Culicoides imicola) was present in abundance during the outbreak. Furthermore, 63% of cases occurred at temperatures < or = 15 degrees C, the Eerste River Valley was a high risk area, only 17% of owners used vector protection as a control measure and 70% of horses in the outbreak area were protected by means of vaccination at the start of the outbreak. The study revealed that the current AHS control measures do not function optimally because of the high percentage of vaccinated horses in the surveillance zone, which results in insufficient sentinel animals and the consequent failure of the early warning system. Alternative options for control that allow continued export are discussed in the paper.  
  Address State Veterinarian Epidemiology, Elsenburg, South Africa. marnas@elsenburg.com  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1019-9128 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:17458343 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2354  
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Author Venter, G.J.; Koekemoer, J.J.O.; Paweska, J.T. openurl 
  Title Investigations on outbreaks of African horse sickness in the surveillance zone in South Africa Type Journal Article
  Year 2006 Publication Revue Scientifique et Technique (International Office of Epizootics) Abbreviated Journal (up) Rev Sci Tech  
  Volume 25 Issue 3 Pages 1097-1109  
  Keywords African Horse Sickness/*epidemiology; African horse sickness virus/genetics/*isolation & purification; Animals; Ceratopogonidae/*virology; Disease Outbreaks/*veterinary; Horses; Insect Vectors/*virology; Prevalence; Sentinel Surveillance/veterinary; South Africa/epidemiology  
  Abstract Confirmed outbreaks of African horse sickness (AHS) occurred in the surveillance zone of the Western Cape in 1999 and 2004, both of which led to a two-year suspension on the export of horses. Light trap surveys in the outbreak areas showed that known vector competent Culicoides species, notably C. imicola, were abundant and present in numbers equal to those in the traditional AHS endemic areas. Isolations of AHS virus serotypes 1 and 7, equine encephalosis virus, and bluetongue virus from field-collected C. imicola in the surveillance zone demonstrated that this species was highly competent and could transmit viruses belonging to different serogroups of the Orbivirus genus. Molecular identification of recovered virus isolates indicated that at least two incursions of AHS into the surveillance zone had taken place in 2004. The designation of an AHS-free zone in the Western Cape remains controversial since it can be easily compromised, as evidenced by the two recent outbreaks. In light of the results reported in the present study, the policy of maintaining a large population of unvaccinated horses in the surveillance zone should be reconsidered, as it leaves them vulnerable to infection with AHS virus, which is the most pathogenic of all equine viruses.  
  Address Agricultural Research Council-Onderstepoort Veterinary Institute, Private Bag X5, Onderstepoort, 0110 South Africa  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0253-1933 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:17361773 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2355  
Permanent link to this record
 

 
Author Ward, M.P.; Ramsay, B.H.; Gallo, K. doi  openurl
  Title Rural cases of equine West Nile virus encephalomyelitis and the normalized difference vegetation index Type Journal Article
  Year 2005 Publication Vector Borne and Zoonotic Diseases (Larchmont, N.Y.) Abbreviated Journal (up) Vector Borne Zoonotic Dis  
  Volume 5 Issue 2 Pages 181-188  
  Keywords Animals; Biomass; Cluster Analysis; Disease Outbreaks/veterinary; Ecology; *Geographic Information Systems; Horse Diseases/*epidemiology; Horses; Indiana/epidemiology; Plants; Population Surveillance; Rural Health; Seasons; Topography, Medical/*methods; West Nile Fever/epidemiology/*veterinary  
  Abstract Data from an outbreak (August to October, 2002) of West Nile virus (WNV) encephalomyelitis in a population of horses located in northern Indiana was scanned for clusters in time and space. One significant (p = 0.04) cluster of case premises was detected, occurring between September 4 and 10 in the south-west part of the study area (85.70 degrees N, 45.50 degrees W). It included 10 case premises (3.67 case premises expected) within a radius of 2264 m. Image data were acquired by the Advanced Very High Resolution Radiometer (AVHRR) sensor onboard a National Oceanic and Atmospheric Administration polar-orbiting satellite. The Normalized Difference Vegetation Index (NDVI) was calculated from visible and near-infrared data of daily observations, which were composited to produce a weekly-1km(2) resolution raster image product. During the epidemic, a significant (p < 0.01) decrease (0.025 per week) in estimated NDVI was observed at all case and control premise sites. The median estimated NDVI (0.659) for case premises within the cluster identified was significantly (p < 0.01) greater than the median estimated NDVI for other case (0.571) and control (0.596) premises during the same period. The difference in median estimated NDVI for case premises within this cluster, compared to cases not included in this cluster, was greatest (5.3% and 5.1%, respectively) at 1 and 5 weeks preceding occurrence of the cluster. The NDVI may be useful for identifying foci of WNV transmission.  
  Address Department of Veterinary Pathobiology, Purdue University School of Veterinary Medicine, West Lafayette, Indiana, USA. mward@cvm.tamu.edu  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1530-3667 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16011435 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2627  
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Author Dargatz, D.A.; Traub-Dargatz, J.L. doi  openurl
  Title Multidrug-resistant Salmonella and nosocomial infections Type Journal Article
  Year 2004 Publication The Veterinary Clinics of North America. Equine Practice Abbreviated Journal (up) Vet Clin North Am Equine Pract  
  Volume 20 Issue 3 Pages 587-600  
  Keywords Animals; Anti-Bacterial Agents/*pharmacology; Cross Infection/prevention & control/*veterinary; Disease Outbreaks/prevention & control/veterinary; Drug Resistance, Bacterial; *Drug Resistance, Multiple, Bacterial; Horse Diseases/*drug therapy/transmission; Horses; Infection Control/methods; Microbial Sensitivity Tests/veterinary; Salmonella/*drug effects; Salmonella Infections, Animal/*drug therapy/transmission  
  Abstract Nosocomial infections are a serious threat to optimum patient care. In addition, nosocomial infections can have far-reaching consequences for the hospital personnel and the financial aspects of the hospital. Nosocomial infections with Salmonella spp have been described among hospitalized equine populations more frequently than any other agent. Salmonella spp associated with hospitalized equids often possess more antimicrobial resistance determinants than do Salmonella spp isolated from healthy horses in the general population. There is little evidence to suggest that resistant salmonellae are more virulent than nonresistant forms. MDR forms of Salmonella complicate the selection of appropriate antimicrobials when they are indicated, however. Furthermore, the use of some antimicrobials may apply selection pressure toward enhanced ability of MDR Salmonella to colonize equine patients. Further research should help to elucidate the risky uses of antimicrobials in the hospital setting and define the role of disinfectants and treatments such as NSAIDs in the ecology of MDR forms of nosocomial infections, including Salmonella. In the meantime, thoughtful selection of when and how to use antimicrobials in equine patients, together with deliberate selection of which antimicrobials to use based on monitoring data and other factors, such as safety and spectrum, is advised.  
  Address Animal and Plant Health Inspection Service, Veterinary Services, Centers for Epidemiology and Animal Health, United States Department of Agriculture, 2150 Centre Avenue, Building MS 2E7, Fort Collins, CO 80521, USA. david.a.dargatz@aphis.usda.gov  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0749-0739 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:15519820 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2632  
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Author Cilnis, M.J.; Kang, W.; Weaver, S.C. doi  openurl
  Title Genetic conservation of Highlands J viruses Type Journal Article
  Year 1996 Publication Virology Abbreviated Journal (up) Virology  
  Volume 218 Issue 2 Pages 343-351  
  Keywords Alphavirus/*genetics; Alphavirus Infections/transmission/veterinary/virology; Amino Acid Sequence; Animals; Base Sequence; Conserved Sequence; Disease Outbreaks; Encephalitis, Viral/veterinary/virology; *Evolution, Molecular; Horses; Molecular Sequence Data; Phylogeny; RNA, Viral/genetics; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Turkeys; Variation (Genetics)/*genetics  
  Abstract We studied molecular evolution of the mosquito-borne alphavirus Highlands J (HJ) virus by sequencing PCR products generated from 19 strains isolated between 1952 and 1994. Sequences of 1200 nucleotides including portions of the E1 gene and the 3' untranslated region revealed a relatively slow evolutionary rate estimated at 0.9-1.6 x 10(-4) substitutions per nucleotide per year. Phylogenetic trees indicated that all HJ viruses descended from a common ancestor and suggested the presence of one dominant lineage in North America. However, two or more minor lineages probably circulated simultaneously for periods of years to a few decades. Strains isolated from a horse suffering encephalitis, and implicated in a recent turkey outbreak, were not phylogenetically distinct from strains isolated in other locations during the same time periods. Our findings are remarkably similar to those we obtained previously for another North American alphavirus, eastern equine encephalomyelitis virus, with which Highlands J shares primary mosquito and avian hosts, geographical distribution, and ecology. These results support the hypotheses that the duration of the transmission season affects arboviral evolutionary rates and vertebrate host mobility influences genetic diversity.  
  Address Department of Biology, University of California, San Diego, La Jolla 92093-0116, USA  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0042-6822 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:8610461 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2657  
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