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Author |
de Waal, F.B.; Uno, H.; Luttrell, L.M.; Meisner, L.F.; Jeannotte, L.A. |
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Title |
Behavioral retardation in a macaque with autosomal trisomy and aging mother |
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Journal Article |
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Year |
1996 |
Publication |
American journal of mental retardation : AJMR |
Abbreviated Journal |
Am J Ment Retard |
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Volume |
100 |
Issue |
4 |
Pages |
378-390 |
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Keywords |
Animals; *Behavior, Animal; Brain/physiopathology; Female; Hydrocephalus/complications; Longitudinal Studies; Macaca mulatta/*genetics; Magnetic Resonance Imaging; Male; *Maternal Age; Psychomotor Disorders/*etiology; Social Behavior; Trisomy/*genetics; X Chromosome |
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Abstract |
The social development of a female rhesus monkey (Macaca mulatta) was followed from the day of birth until her death, at age 32 months. The subject, born to an older mother, had an extra autosome (karyotype: 43, XX, +18), an affliction that came about spontaneously. MRI scans revealed that she was also hydrocephalic. Compared to 23 female monkeys growing up under identical conditions, the subject showed serious motor deficiencies, a dramatic delay in the development of social behavior, poorly established dominance relationships, and greater than usual dependency on mother and kin. The subject was well-integrated into the social group, however. |
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University of Wisconsin-Madison, USA |
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0895-8017 |
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PMID:8718992 |
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no |
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Call Number |
refbase @ user @ |
Serial |
205 |
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Author |
Stock, K.F.; Distl, O. |
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Title |
Evaluation of expected response to selection for orthopedic health and performance traits in Hanoverian Warmblood horses |
Type |
Journal Article |
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Year |
2005 |
Publication |
American Journal of Veterinary Research |
Abbreviated Journal |
Am J Vet Res |
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Volume |
66 |
Issue |
8 |
Pages |
1371-1379 |
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Keywords |
Animals; Bone Diseases/genetics/*veterinary; *Breeding; Genetic Predisposition to Disease; Horse Diseases/*genetics; Horses/*genetics; Joint Diseases/genetics/*veterinary; Selection (Genetics) |
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Abstract |
OBJECTIVE: To determine whether selection schemes accounting for orthopedic health traits were compatible with breeding progress in performance parameters in Hanoverian Warmblood horses. ANIMALS: 5,928 horses. PROCEDURE: Relative breeding values (RBVs) were predicted for osseous fragments in fetlock (metacarpo- and metatarsophalangeal) and tarsal joints, deforming arthropathy in tarsal joints, and pathologic changes in distal sesamoid bones. Selection schemes were developed on the basis of total indices for radiographic findings (TIR), dressage (TID), and jumping (TIJ). Response to selection was traced over 2 generations of horses for dressage and jumping ability and all-purpose breeding. Development of mean RBVs and mean total indices in sires and prevalences of orthopedic health traits in their offspring were used to assess response to selection. RESULTS: Giving equal weight toTIR andTID, TIJ, or a combined index of 60% TID and 40% TIJ, 43% to 53% of paternal grandsires and 70% to 82% of descending sires passed selection. In each case, RBVs and total indices increased by as much as 9% in selected sires, when compared with all sires, and prevalences of orthopedic health traits in offspring of selected sires decreased relatively by as much as 16%. When selection was exclusively based on TID, TIJ, or TID and TIJ, percentages of selected sires were 44% to 66% in the first and 73% to 84% in the second generation and TID and TIJ increased by 9% to 10% and 19% to 23%, respectively. CONCLUSIONS AND CLINICAL RELEVANCE: Compared with exclusively performance-based selection, percentages of selected sires changed slightly and breeding progress in TID, TIJ, or TID and TIJ was only slightly decreased; however, prevalences of orthopedic health traits decreased in offspring of TIR-selected sires. |
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Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover (Foundation), Bunteweg 17p, 30559 Hannover, Germany |
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0002-9645 |
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Notes |
PMID:16173480 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3713 |
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Author |
Nettle, D. |
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Title |
The evolution of personality variation in humans and other animals |
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Journal Article |
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Year |
2006 |
Publication |
The American Psychologist |
Abbreviated Journal |
Am Psychol |
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Volume |
61 |
Issue |
6 |
Pages |
622-631 |
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Keywords |
Animals; Birds; *Evolution; Female; Fishes; Humans; Insects; Male; Personality/*genetics/*physiology |
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Abstract |
A comprehensive evolutionary framework for understanding the maintenance of heritable behavioral variation in humans is yet to be developed. Some evolutionary psychologists have argued that heritable variation will not be found in important, fitness-relevant characteristics because of the winnowing effect of natural selection. This article propounds the opposite view. Heritable variation is ubiquitous in all species, and there are a number of frameworks for understanding its persistence. The author argues that each of the Big Five dimensions of human personality can be seen as the result of a trade-off between different fitness costs and benefits. As there is no unconditionally optimal value of these trade-offs, it is to be expected that genetic diversity will be retained in the population. |
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Address |
University of Newcastle, Newcastle, United Kingdom. daniel.nettle@ncl.ac.uk |
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0003-066X |
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Notes |
PMID:16953749 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4105 |
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Author |
Ishida, N.; Hirano, T.; Mukoyama, H. |
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Title |
Detection of aberrant alleles in the D-loop region of equine mitochondrial DNA by single-strand conformation polymorphism (SSCP) analysis |
Type |
Journal Article |
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Year |
1994 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
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Volume |
25 |
Issue |
4 |
Pages |
287 |
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Keywords |
*Alleles; Animals; Base Sequence; *DNA, Mitochondrial; DNA, Single-Stranded/genetics; Female; Gene Frequency; Genomic Imprinting; Horses/*genetics; Male; Molecular Sequence Data; Pedigree; *Polymorphism, Genetic |
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Laboratory of Molecular and Cellular Biology, Japan Racing Association, Tokyo |
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0268-9146 |
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Notes |
PMID:7985852 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2213 |
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Author |
Momozawa, Y.; Takeuchi, Y.; Tozaki, T.; Kikusui, T.; Hasegawa, T.; Raudsepp, T.; Chowdhary, B.P.; Kusunose, R.; Mori, Y. |
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Title |
SNP detection and radiation hybrid mapping in horses of nine candidate genes for temperament |
Type |
Journal Article |
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Year |
2007 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
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Volume |
38 |
Issue |
1 |
Pages |
81-83 |
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Keywords |
Animals; *Behavior, Animal; Breeding; Horses/*genetics/physiology; *Polymorphism, Single Nucleotide; Radiation Hybrid Mapping; *Temperament |
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Address |
Laboratory of Veterinary Ethology, The University of Tokyo, Tokyo 113-8657, Japan |
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0268-9146 |
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Notes |
PMID:17257195 |
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no |
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Serial |
1834 |
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Author |
Breen, M.; Downs, P.; Irvin, Z.; Bell, K. |
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Title |
Intrageneric amplification of horse microsatellite markers with emphasis on the Przewalski's horse (E. przewalskii) |
Type |
Journal Article |
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Year |
1994 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
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Volume |
25 |
Issue |
6 |
Pages |
401-405 |
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Keywords |
Animals; DNA, Satellite/*genetics; *Gene Amplification; Gene Frequency; *Genetic Markers; Heterozygote; Horses/*genetics; Species Specificity |
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Abstract |
Primer sequences flanking 13 microsatellite loci isolated from the domestic horse (E. caballus) were successfully used to amplify homologous loci in the Przewalski's horse (E. przewalskii). The results demonstrate that the level of polymorphism at all 13 loci in the Przewalski's horse was comparable to that in the domestic horse and the overall exclusion probability in the Przewalski's horse was calculated to be 0.9994. The results suggest that it should be possible to use E. caballus-derived microsatellite markers to provide parentage verification and additional valuable information to the captive management of E. przewalskii. The ability to amplify corresponding loci in the remaining five species of the genus was also confirmed, illustrating the general application of markers isolated from the domestic horse to the evaluation of polymorphism in the other six species of the genus. |
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Address |
Australian Equine Blood Typing Research Laboratory, University of Queensland, St Lucia |
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0268-9146 |
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Notes |
PMID:7695120 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2246 |
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Permanent link to this record |
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Author |
Wallner, B.; Brem, G.; Muller, M.; Achmann, R. |
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Title |
Fixed nucleotide differences on the Y chromosome indicate clear divergence between Equus przewalskii and Equus caballus |
Type |
Journal Article |
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Year |
2003 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
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Volume |
34 |
Issue |
6 |
Pages |
453-456 |
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Keywords |
Animals; Base Sequence; DNA, Mitochondrial/genetics; Genetic Variation/*genetics; Horses/classification/*genetics; Male; Molecular Sequence Data; Phylogeny; Probability; Species Specificity; Y Chromosome/*genetics |
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Abstract |
The phylogenetic relationship between Equus przewalskii and E. caballus is often a matter of debate. Although these taxa have different chromosome numbers, they do not form monophyletic clades in a phylogenetic tree based on mtDNA sequences. Here we report sequence variation from five newly identified Y chromosome regions of the horse. Two fixed nucleotide differences on the Y chromosome clearly display Przewalski's horse and domestic horse as sister taxa. At both positions the Przewalski's horse haplotype shows the ancestral state, in common with the members of the zebra/ass lineage. We discuss the factors that may have led to the differences in mtDNA and Y-chromosomal observations. |
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Address |
Institut fur Tierzucht und Genetik, Veterinarmedizinische Universitat Wien, Veterinarplatz, Wien, Austria. wallner@i122server.vu-wien.ac.at |
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0268-9146 |
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Notes |
PMID:14687077 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
5038 |
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Author |
Oakenfull, E.A.; Ryder, O.A. |
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Title |
Mitochondrial control region and 12S rRNA variation in Przewalski's horse (Equus przewalskii) |
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Journal Article |
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Year |
1998 |
Publication |
Animal Genetics |
Abbreviated Journal |
Anim Genet |
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Volume |
29 |
Issue |
6 |
Pages |
456-459 |
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Keywords |
Animals; DNA, Mitochondrial/*genetics; Female; *Genetic Variation; Horses/*genetics; Male; Pedigree; RNA, Ribosomal/*genetics |
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Abstract |
Variation in the control region and the 12S rRNA gene of all surviving mitochondrial lineages of Przewalski's horse was investigated. Variation is low despite the present day population being descended from 13 individuals probably representing animals from three different regions of its range. Phylogenetic comparison of these sequences, with sequences for the domestic horse, does not resolve the ancestral status of either horse. |
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Center for Reproduction of Endangered Species, Zoological Society of San Diego, CA 92112, USA |
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0268-9146 |
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Notes |
PMID:9883508 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
5040 |
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Author |
Chilton, N.B. |
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Title |
The use of nuclear ribosomal DNA markers for the identification of bursate nematodes (order Strongylida) and for the diagnosis of infections |
Type |
Journal Article |
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Year |
2004 |
Publication |
Animal Health Research Reviews / Conference of Research Workers in Animal Diseases |
Abbreviated Journal |
Anim Health Res Rev |
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Volume |
5 |
Issue |
2 |
Pages |
173-187 |
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Keywords |
Animals; Birds; Cats; DNA Primers; DNA, Helminth/*analysis; DNA, Ribosomal/*analysis; Dogs; Horses; Molecular Diagnostic Techniques/veterinary; Ruminants; Strongylida/*genetics; Strongylida Infections/diagnosis/*veterinary |
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Abstract |
Many bursate nematodes are of major importance to animal health. Animals are often parasitized by multiple species that differ in their prevalence, relative abundance and/or pathogenicity. Implementation of effective management strategies for these parasites requires reliable methods for their detection in hosts, identification to the species level and measurement of intensity of infection. One major problem is the difficulty of accurately identifying and distinguishing many species of bursate nematode because of the remarkable morphological similarity of their eggs and larvae. The inability to identify, with confidence, individual nematodes (irrespective of their life-cycle stage) to the species level by morphological methods has often led to a search for species-specific genetic markers. Studies over the past 15 years have shown that sequences of the internal transcribed spacers of ribosomal DNA provide useful genetic markers, providing the basis for the development of PCR-based diagnostic tools. Such molecular methods represent powerful tools for studying the systematics, epidemiology and ecology of bursate nematodes and, importantly, for the specific diagnosis of infections in animals and humans, thus contributing to improved control and prevention strategies for these parasites. |
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Department of Biology, University of Saskatchewan, 112 Science Place, Saskatoon, Saskatchewan S7N 5E2, Canada. neil.chilton@usask.ca |
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ISSN |
1466-2523 |
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Notes |
PMID:15984323 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2628 |
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Permanent link to this record |
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Author |
Morley, K.I.; Montgomery, G.W. |
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Title |
The genetics of cognitive processes: candidate genes in humans and animals |
Type |
Journal Article |
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Year |
2001 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
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Volume |
31 |
Issue |
6 |
Pages |
511-531 |
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Keywords |
Animals; *Chromosome Mapping; Drosophila melanogaster; Genetic Markers/*genetics; Humans; Intelligence/*genetics; Mental Retardation/genetics; Mice; Phenotype; Quantitative Trait, Heritable |
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Abstract |
It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition was compiled. Some genes are particularly strong candidates based on evidence for involvement in cognitive processes in humans, mice, and Drosophila melanogaster. This survey confirms that many genes are associated with cognitive variation and highlights the potential importance of animal models in the study of human cognition. |
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Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia |
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0001-8244 |
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Notes |
PMID:11838530 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4141 |
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Permanent link to this record |