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Workshop on the geographic spread of Aedes albopictus in Europe and the concern among public health authorities. Proceedings of a workshop held at the Istituto Superiore di Sanita, Rome, Italy, 19-20 December 1994 |
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Conference Article |
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1995 |
Publication |
Parassitologia |
Abbreviated Journal |
Parassitologia |
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37 |
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2-3 |
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87-90 |
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*Aedes/growth & development/parasitology/virology; African horse sickness virus; Animals; Commerce; Dengue Virus; Dirofilaria; Disease Reservoirs; Ecology; Europe; Humans; *Insect Vectors/growth & development/parasitology/virology; Italy; *Mosquito Control/methods/organization & administration; Public Health; Rift Valley fever virus |
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0048-2951 |
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PMID:8778669 |
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Equine Behaviour @ team @ |
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2659 |
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Author |
Scheibe, K.M.; Gromann, C. |
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Application testing of a new three-dimensional acceleration measuring system with wireless data transfer (WAS) for behavior analysis |
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Year |
2006 |
Publication |
Behavior research methods |
Abbreviated Journal |
Behav Res Methods |
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38 |
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3 |
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427-433 |
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Acceleration; Animals; *Behavior, Animal; Cattle; Cattle Diseases/*diagnosis; Computer Communication Networks/*instrumentation; Forelimb/physiopathology; Fractals; Hindlimb/physiopathology; Horse Diseases/*diagnosis; Horses; Imaging, Three-Dimensional/instrumentation/methods/veterinary; Lameness, Animal/*diagnosis; Monitoring, Ambulatory/instrumentation/*methods; Motor Activity; Movement; Pattern Recognition, Automated/methods |
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A wireless acceleration measurement system was applied to free-moving cows and horses. Sensors were available as a collar and a flat box for measuring leg or trunk movements. Results were transmitted simultaneously by radio or stored in an 8-MB internal memory. As analytical procedures, frequency distributions with standard deviations, spectral analyses, and fractal analyses were applied. Bymeans of the collar sensor, basic behavior patterns (standing, grazing, walking, ruminating, drinking, and hay uptake) could be identified in cows. Lameness could be detected in cows and horses by means of the leg sensor. The portion of basic and harmonic spectral components was reduced; the fractal dimension was reduced. The system can be used for the detection and analysis of even small movements of free-moving humans or animals over several hours. It is convenient for the analysis of basic behaviors, emotional reactions, or events causing flight or fright or for comparing different housing elements, such as floors or fences. |
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Institute for Zoo and Wildlife Research, Berlin, Germany. kscheibe@izw-berlin.de |
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1554-351X |
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PMID:17186752 |
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1775 |
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Author |
Jonsson, H.; Egenvall, A. |
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Title |
Prevalence of gastric ulceration in Swedish Standardbreds in race training |
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Journal Article |
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Year |
2006 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
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Volume |
38 |
Issue |
3 |
Pages |
209-213 |
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Keywords |
Age Factors; Animal Feed; Animals; Cross-Sectional Studies; Female; Gastric Mucosa/pathology; Gastroscopy/methods/veterinary; Horse Diseases/*epidemiology/etiology/pathology; Horses; Male; Physical Conditioning, Animal/*adverse effects; Prevalence; Questionnaires; Severity of Illness Index; Sex Factors; Sports; Stomach Ulcer/epidemiology/etiology/pathology/*veterinary; Sweden/epidemiology |
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Abstract |
REASONS FOR PERFORMING STUDY: There is little information about the prevalence of gastric ulcers in Standardbred trotters and potential correlations between ulcers and various traits, e.g. age, sex, performance, temperament and feeding regimens, need further elucidation. OBJECTIVES: The prevalence of ulcers in the gastric squamous mucosa of Swedish Standardbreds was estimated and the associations between ulcer score and age, sex, performance, temperament and feeding regimens were determined. METHODS: Eighty Swedish Standardbreds in active race training, trained by 9 different trainers, underwent gastroscopy. Information on age, gender, status of training, performance over the last 4 months compared with the trainer's expectations before that period, behaviour, eating habits, feed type, bedding type, time spent outdoors per day and medical treatment during the last month was collected. Gastroscopy was performed and lesions in the squamous gastric mucosa were scored from 0 to 4 (0 = no lesions; 4 = > 5 lesions with haemorrhage, > 10 lesions with no haemorrhage, or a large area of diffuse loss of surface epithelium). RESULTS: Twenty-four (30%) of the horses had no lesions in the squamous mucosa, 22 (27.5%) had a score of 1; 21 (26.2%) score 2; 9 (11.2%) score 3; and 4 (5%) score 4. Horses that were in preparatory training and those that had raced during the last month were significantly more affected than horses that were fit for racing but had not raced during the last month, using a logistic regression model with trainer incorporated as a random effect. CONCLUSIONS: The study confirmed a high prevalence of ulcers in the gastric squamous mucosa of Standardbreds in race training. Of the studied parameters only status of training showed a significant association with gastric ulcers of the squamous mucosa. POTENTIAL RELEVANCE: Gastric ulceration is a common disease and diagnosis should be made by endoscopic examination of the gastric mucosa, since parameters such as age, gender, performance, behaviour, eating habits provide only weak clues as to which horses might be affected. Further studies are needed to determine the aetiology of the syndrome and to find ways to reduce, if possible, the frequency of gastric ulcers. |
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ATG:s Hastsjukhus Farjestad, Norra Infarten 82, SE-654 65 Karlstad, Sweden |
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0425-1644 |
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PMID:16706273 |
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Serial |
1870 |
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Author |
Robertson, S. |
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Title |
The importance of assessing pain in horses and donkeys |
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Journal Article |
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Year |
2006 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
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38 |
Issue |
1 |
Pages |
5-6 |
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Keywords |
Animals; *Behavior, Animal/physiology; Equidae/*physiology; Horses/physiology; Pain/diagnosis/prevention & control/*veterinary; Pain Measurement/methods/*veterinary; Veterinary Medicine/*methods |
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Section of Anaesthesia and Pain Management, College of Veterinary of Medicine, University of Florida, Gainesville 32610-0136, USA |
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0425-1644 |
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PMID:16411578 |
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Call Number |
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Serial |
1881 |
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Author |
Kristiansen, K.K.; Kold, S.E. |
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Title |
Multivariable analysis of factors influencing outcome of 2 treatment protocols in 128 cases of horses responding positively to intra-articular analgesia of the distal interphalangeal joint |
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Journal Article |
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Year |
2007 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
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39 |
Issue |
2 |
Pages |
150-156 |
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Keywords |
Analgesia/methods/*veterinary; Anesthesia, Local/methods/veterinary; Animals; Anti-Inflammatory Agents/therapeutic use; Female; Foot Diseases/drug therapy/prevention & control/*veterinary; Glycosaminoglycans/therapeutic use; Horse Diseases/*drug therapy/prevention & control; Horses; Injections, Intra-Articular/*veterinary; Joint Diseases/drug therapy/prevention & control/veterinary; Lameness, Animal/drug therapy/prevention & control; Male; Methylprednisolone/analogs & derivatives/therapeutic use; Multivariate Analysis; Pain/prevention & control/veterinary; Retrospective Studies; Time Factors; *Toe Joint/drug effects/pathology; Treatment Outcome |
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Abstract |
REASONS FOR PERFORMING STUDY: There is limited knowledge available of factors influencing response to treatments of the DIP-joint in horses with lameness responding to diagnostic analgesia of the DIP-joint. For this reason a multivariable statistical analysis was performed. HYPOTHESIS: Horses with lameness reduced by > or = 75% 10 min after intra-articular analgesia of the DIP-joint, can be treated successfully by intra-articular medication of the joint. Multiple factors influence the response to treatment. METHODS: The study was performed retrospectively based on clinical records of horses treated with either polysulphated glycosaminoglycan (PSGAG) or methylprednisolone acetate (MPA) in the DIP-joint between January 1996 and January 2003. Information was collected from clinical records and from the owners of the horses via a detailed questionnaire, in which they described their perception of the outcome a minimum of one year after treatment. Allocation of the horses to the 2 treatment groups was done mainly because of a change in treatment policy. In Regime A all horses received 3 intra-articular injections of PSGAG approximately 8 days apart, whereas in Regime B all horses received a single intra-articular injection of MPA as a first treatment. If the horse did not improve sufficiently to return to work by 4 weeks, a series of 3 intra-articular PSGAG injections was administered. RESULTS: Of the horses receiving Regime A, 67% had a successful outcome, compared with 46% of the group receiving Regime B. A significantly better result was obtained in dressage horses than in jumping horses (eventing and showjumping). Other variables such as age, duration of lameness, distribution of lameness, degree of lameness, response to DIP-joint analgesia and radiographic observations were also associated with success of treatment. CONCLUSIONS AND POTENTIAL RELEVANCE: There is a rationale for using either PSGAG or MPA intra-articularly in the treatment of lameness, reduced > or = 75% within 10 min of analgesia of the DIP-joint. |
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Willesley Equine Clinic Ltd., Tetbury, Gloucestershire, GL8 8QU UK |
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0425-1644 |
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PMID:17378444 |
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Equine Behaviour @ team @ |
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3707 |
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Author |
Verheyen, K.; Price, J.; Lanyon, L.; Wood, J. |
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Title |
Exercise distance and speed affect the risk of fracture in racehorses |
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Journal Article |
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Year |
2006 |
Publication |
Bone |
Abbreviated Journal |
Bone |
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39 |
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6 |
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1322-1330 |
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Keywords |
Animals; Case-Control Studies; Cohort Studies; England; Exertion; Female; Fractures, Bone/etiology/*veterinary; Horse Diseases/*etiology; Horses/*injuries; Male; Physical Conditioning, Animal/adverse effects/methods; Poisson Distribution; Prospective Studies; Regression Analysis; Risk Factors; Running/injuries/physiology |
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Abstract |
In order to gain insight into those training regimens that can minimise the risk of fracture in athletic populations, we conducted a large epidemiological study in racehorses. Thoroughbred racehorses provide a suitable model for studying fracture development and exercise-related risk factors in physically active populations. They represent a homogeneous population, undertaking intensive exercise programmes that are sufficiently heterogeneous to determine those factors that influence injury risk. Daily exercise information was recorded for a cohort of 1178 thoroughbreds that were monitored for up to 2 years. A total of 148 exercise-induced fractures occurred in the study population. Results from a nested case-control study showed a strong interactive effect of exercise distances at different speeds on fracture risk. Horses that exceeded 44 km at canter (< or =14 m/s) and 6 km at gallop (>14 m/s) in a 30-day period were at particularly increased risk of fracture. These distances equate to ca. 7700 bone loading cycles at canter and 880 loading cycles at gallop. Fifty-six fractures occurred in the subset of study horses that were followed since entering training as yearlings, when skeletally immature (n = 335). Cohort analysis of this data set showed that, in previously untrained bones, accumulation of canter exercise increased the risk of fracture (P < or = 0.01), whereas accumulation of high-speed gallop exercise had a protective effect (P < 0.01). However, increasing distances at canter and gallop in short time periods (up to one month) were associated with an increasing fracture risk. All training exercise involves a balance between the risk of fracture inherent in exposure to loading and the beneficial effect that loading has by stimulating bone cells to produce a more robust architecture. Results from our study provide important epidemiological evidence of the effects of physical exercise on bone adaptation and injury risk and can be used to inform the design of safer exercise regimens in physically active populations. |
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Epidemiology Unit, Animal Health Trust, Newmarket, United Kingdom. kverheyen@rvc.ac.uk |
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8756-3282 |
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PMID:16926125 |
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Call Number |
Equine Behaviour @ team @ |
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4030 |
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Author |
Thomas, K.E.; Annest, J.L.; Gilchrist, J.; Bixby-Hammett, D.M. |
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Non-fatal horse related injuries treated in emergency departments in the United States, 2001-2003 |
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Year |
2006 |
Publication |
British Journal of Sports Medicine |
Abbreviated Journal |
Br J Sports Med |
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Volume |
40 |
Issue |
7 |
Pages |
619-626 |
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Keywords |
Accident Prevention/methods; Accidental Falls/prevention & control; Adolescent; Adult; Aged; Animals; Athletic Injuries/*epidemiology/prevention & control; Child; Child, Preschool; Emergency Service, Hospital/*statistics & numerical data; Female; Head Protective Devices/utilization; Health Promotion; *Horses; Humans; Infant; Male; Middle Aged; Patient Education; Sex Distribution; United States/epidemiology |
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OBJECTIVE: To characterise and provide nationally representative estimates of persons with non-fatal horse related injuries treated in American emergency departments. METHODS: The National Electronic Injury Surveillance System All Injury Program (NEISS-AIP) is a stratified probability sample comprising 66 hospitals. Data on injuries treated in these emergency departments are collected and reported. NEISS-AIP data on all types (horseback riding and otherwise) of non-fatal horse related injuries from 2001 to 2003 were analysed. RESULTS: An estimated 102,904 persons with non-fatal horse related injuries (35.7 per 100,000 population) were treated in American emergency departments each year from 2001 to 2003 inclusive. Non-fatal injury rates were higher for females (41.5 per 100,000) than for males (29.8 per 100,000). Most patients were injured while mounted on a horse (66.1%), commonly from falling or being thrown by the horse; while not mounted, injuries most often resulted from being kicked by the horse. The body parts most often injured were the head/neck region (23.2%), lower extremity (22.2%), and upper extremity (21.5%). The most common principal diagnoses were contusions/abrasions (31.4%) and fractures (25.2%). For each year that was studied, an estimated 11 502 people sustained traumatic brain injuries from horse related incidents. Overall, more than 11% of those injured were admitted to hospital. CONCLUSIONS: Horse related injuries are a public health concern not just for riders but for anyone in close contact with horses. Prevention programmes should target horseback riders and horse caregivers to promote helmet use and educate participants about horse behaviour, proper handling of horses, and safe riding practices. |
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Office of Statistics and Programming, National Center for Injury Prevention and Control, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. KEThomas@cdc.gov |
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1473-0480 |
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Notes |
PMID:16611723 |
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no |
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Call Number |
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Serial |
1866 |
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Author |
Gulotta, M.; Gilmanshin, R.; Buscher, T.C.; Callender, R.H.; Dyer, R.B. |
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Title |
Core formation in apomyoglobin: probing the upper reaches of the folding energy landscape |
Type |
Journal Article |
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Year |
2001 |
Publication |
Biochemistry |
Abbreviated Journal |
Biochemistry |
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Volume |
40 |
Issue |
17 |
Pages |
5137-5143 |
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Keywords |
Animals; Apoproteins/*chemistry; Computer Simulation; Horses; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Myoglobin/*chemistry; *Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence/instrumentation/methods; Thermodynamics; Tryptophan/chemistry |
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Abstract |
An acid-destabilized form of apomyoglobin, the so-called E state, consists of a set of heterogeneous structures that are all characterized by a stable hydrophobic core composed of 30-40 residues at the intersection of the A, G, and H helices of the protein, with little other secondary structure and no other tertiary structure. Relaxation kinetics studies were carried out to characterize the dynamics of core melting and formation in this protein. The unfolding and/or refolding response is induced by a laser-induced temperature jump between the folded and unfolded forms of E, and structural changes are monitored using the infrared amide I' absorbance at 1648-1651 cm(-1) that reports on the formation of solvent-protected, native-like helix in the core and by fluorescence emission changes from apomyoglobin's Trp14, a measure of burial of the indole group of this residue. The fluorescence kinetics data are monoexponential with a relaxation time of 14 micros. However, infrared kinetics data are best fit to a biexponential function with relaxation times of 14 and 59 micros. These relaxation times are very fast, close to the limits placed on folding reactions by diffusion. The 14 micros relaxation time is weakly temperature dependent and thus represents a pathway that is energetically downhill. The appearance of this relaxation time in both the fluorescence and infrared measurements indicates that this folding event proceeds by a concomitant formation of compact secondary and tertiary structures. The 59 micros relaxation time is much more strongly temperature dependent and has no fluorescence counterpart, indicating an activated process with a large energy barrier wherein nonspecific hydrophobic interactions between helix A and the G and H helices cause some helix burial but Trp14 remains solvent exposed. These results are best fit by a multiple-pathway kinetic model when U collapses to form the various folded core structures of E. Thus, the results suggest very robust dynamics for core formation involving multiple folding pathways and provide significant insight into the primary processes of protein folding. |
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Department of Biochemistry, Albert Einstein College of Medicine, Bronx, New York 10461, USA |
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0006-2960 |
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PMID:11318635 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3789 |
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Author |
Haruta, N.; Kitagawa, T. |
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Title |
Time-resolved UV resonance Raman investigation of protein folding using a rapid mixer: characterization of kinetic folding intermediates of apomyoglobin |
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Journal Article |
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Year |
2002 |
Publication |
Biochemistry |
Abbreviated Journal |
Biochemistry |
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Volume |
41 |
Issue |
21 |
Pages |
6595-6604 |
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Keywords |
Animals; Apoproteins/*chemistry; Circular Dichroism; Holoenzymes/chemistry; Horses; Hydrochloric Acid/chemistry; Hydrogen-Ion Concentration; Imidazoles/chemistry; Kinetics; Models, Molecular; Myoglobin/*chemistry; Peptide Fragments/chemistry; *Protein Folding; Protein Structure, Secondary; Spectrum Analysis, Raman/*methods; Tryptophan/*chemistry; Ultraviolet Rays; Whales |
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Abstract |
The 244-nm excited transient UV resonance Raman spectra are observed for the refolding intermediates of horse apomyoglobin (h-apoMb) with a newly constructed mixed flow cell system, and the results are interpreted on the basis of the spectra observed for the equilibrium acid unfolding of the same protein. The dead time of mixing, which was determined with the appearance of UV Raman bands of imidazolium upon mixing of imidazole with acid, was 150 micros under the flow rate that was adopted. The pH-jump experiments of h-apoMb from pH 2.2 to 5.6 conducted with this device demonstrated the presence of three folding intermediates. On the basis of the analysis of W3 and W7 bands of Trp7 and Trp14, the first intermediate, formed before 250 micros, involved incorporation of Trp14 into the alpha-helix from a random coil. The frequency shift of the W3 band of Trp14 observed for this process was reproduced with a model peptide of the A helix when it forms the alpha-helix. In the second intermediate, formed around 1 ms after the start of refolding, the surroundings of both Trp7 and Trp14 were significantly hydrophobic, suggesting the formation of the hydrophobic core. In the third intermediate appearing around 3 ms, the hydrophobicity was relaxed to the same level as that of the pH 4 equilibrium intermediate, which was investigated in detail with the stationary state technique. The change from the third intermediate to the native state needs more time than 40 ms, while the appearance of the native spectrum after the mixing of the same solutions was confirmed separately. |
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School of Mathematical and Physical Sciences, The Graduate University for Advanced Studies, Myodaiji, Okazaki 444-8585, Japan |
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0006-2960 |
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PMID:12022863 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3785 |
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Author |
Griffin, B. |
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Title |
The use of fecal markers to facilitate sample collection in group-housed cats |
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Journal Article |
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Year |
2002 |
Publication |
Contemporary Topics in Laboratory Animal Science / American Association for Laboratory Animal Science |
Abbreviated Journal |
Contemp Top Lab Anim Sci |
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Volume |
41 |
Issue |
2 |
Pages |
51-56 |
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Keywords |
Animals; Behavior, Animal; Biological Markers/*analysis; Cats/*physiology/psychology; Diet/veterinary; Feces/*chemistry; Food Coloring Agents/analysis; Housing, Animal; Individuality; Plastics/analysis; Specimen Handling/methods/*veterinary |
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Abstract |
The provision of proper social housing is a priority when designing an experiment using domestic cats as laboratory animals. When animals are group-housed, studies requiring analysis of stool samples from individual subjects pose difficulty in sample collection and identification. In this study, commercially available concentrated food colorings (known as bakers pastes) were used as fecal markers in group-housed cats. Cats readily consumed 0.5 ml of bakers paste food coloring once daily in canned cat food. Colorings served as fecal markers by imparting a distinct color to each cat s feces, allowing identification in the litter box. In addition, colored glitter (1/8 teaspoon in canned food) was fed to cats and found to be a reliable fecal marker. Long-term feeding of colorings and glitter was found to be safe and effective at yielding readily identifiable stools. |
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Address |
Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Alabama 36841, USA |
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English |
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ISSN |
1060-0558 |
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Notes |
PMID:11958604 |
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Call Number |
Equine Behaviour @ team @ |
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4165 |
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