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Dwan, K.; Altman, D.G.; Arnaiz, J.A.; Bloom, J.; Chan, A.-W.; Cronin, E.; Decullier, E.; Easterbrook, P.J.; Von Elm, E.; Gamble, C.; Ghersi, D.; Ioannidis, J.P.A.; Simes, J.; Williamson, P.R. |
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Title |
Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias |
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Journal Article |
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Year |
2008 |
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Plos One |
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Plos One |
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3 |
Issue |
8 |
Pages |
e3081 |
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Background The increased use of meta-analysis in systematic reviews of healthcare interventions has highlighted several types of bias that can arise during the completion of a randomised controlled trial. Study publication bias has been recognised as a potential threat to the validity of meta-analysis and can make the readily available evidence unreliable for decision making. Until recently, outcome reporting bias has received less attention. Methodology/Principal Findings We review and summarise the evidence from a series of cohort studies that have assessed study publication bias and outcome reporting bias in randomised controlled trials. Sixteen studies were eligible of which only two followed the cohort all the way through from protocol approval to information regarding publication of outcomes. Eleven of the studies investigated study publication bias and five investigated outcome reporting bias. Three studies have found that statistically significant outcomes had a higher odds of being fully reported compared to non-significant outcomes (range of odds ratios: 2.2 to 4.7). In comparing trial publications to protocols, we found that 40-62% of studies had at least one primary outcome that was changed, introduced, or omitted. We decided not to undertake meta-analysis due to the differences between studies. Conclusions Recent work provides direct empirical evidence for the existence of study publication bias and outcome reporting bias. There is strong evidence of an association between significant results and publication; studies that report positive or significant results are more likely to be published and outcomes that are statistically significant have higher odds of being fully reported. Publications have been found to be inconsistent with their protocols. Researchers need to be aware of the problems of both types of bias and efforts should be concentrated on improving the reporting of trials. |
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Public Library of Science |
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Equine Behaviour @ team @ |
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6644 |
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Author |
Bateson, P. |
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Title |
Play, playfulness, creativity and innovation. |
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Journal Article |
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2014 |
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Animal Behavior and Cognition |
Abbreviated Journal |
Anim. Behav. Cogn. |
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1 |
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2 |
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99-112 |
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Equine Behaviour @ team @ |
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6553 |
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Broekhuis, F.; Madsen, E.K.; Klaassen, B. |
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Title |
Predators and pastoralists: how anthropogenic pressures inside wildlife areas influence carnivore space use and movement behaviour |
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2019 |
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Animal Conservation |
Abbreviated Journal |
Anim Conserv |
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cheetah; livestock; movement; human pressure; protected areas; space use |
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Abstract Across the globe, wildlife populations and their behaviours are negatively impacted by people. Protected areas are believed to be an antidote to increasing human pressures but even they are not immune to the impact of anthropogenic activities. Areas that have been set aside for the protection of wildlife therefore warrant more attention when investigating the impact of anthropogenic pressures on wildlife. We use cheetahs Acinonyx jubatus as a case study to explore how a large carnivore responds to anthropogenic pressures inside wildlife areas. Using GPS-collar data we investigate cheetah space use, both when moving and stationary, and movement parameters (speed and turn angles) in relation to human disturbance, distance to human settlement, livestock abundance and livestock site use inside wildlife areas. Space use was negatively influenced by human disturbance, resulting in habitat loss and fragmentation and potentially reducing landscape permeability between neighbouring wildlife areas. Cheetahs were also less likely to stop in areas where livestock numbers were high, but more likely to stop in areas that were frequently used by livestock. The latter could reflect that cheetahs are attracted to livestock however, cheetahs in the study area rarely predated on livestock. It is therefore more likely that areas that are frequently used by livestock attract wild herbivores, which in turn could influence cheetah space use. We did not find any effects of people and livestock on cheetahs? speed and turn angles which might be related to the resolution of the data. We found that cheetahs are sensitive to human pressures and we believe that they could be an indicator species for other large carnivores facing similar challenges. We suggest that further research is needed to determine the levels of anthropogenic pressures needed to maintain ecological integrity, especially inside wildlife areas. |
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John Wiley & Sons, Ltd (10.1111) |
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1367-9430 |
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doi: 10.1111/acv.12483 |
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Equine Behaviour @ team @ |
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6522 |
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Lee, P. |
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Title |
Adaptation to environmental change:an evolutionary perspective |
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1991 |
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Primate responses to environmental changes |
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39-56 |
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Chapmann & Hall |
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London |
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H. O. Box |
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Equine Behaviour @ team @ |
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6523 |
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Beck, B. B. |
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Title |
Animal tool behaviour: The use and manufacture of tools by animals |
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1980 |
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Garland |
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New York |
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no |
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Equine Behaviour @ team @ |
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6524 |
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Fisher, J.; Hinde, R. A. |
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Title |
The opening of milk bottles by birds |
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1994 |
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British Birds |
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British Birds |
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42 |
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347-357 |
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Equine Behaviour @ team @ |
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6525 |
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Author |
Thorpe, W. H. |
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Title |
Learning and Instinct in Animals. |
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1963 |
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Methuen |
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Equine Behaviour @ team @ |
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6527 |
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Author |
Reader, S. M.; Laland, K.N. |
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Title |
Animal Innovation |
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2003 |
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Oxford University Press |
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Oxford |
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Equine Behaviour @ team @ |
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6531 |
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Author |
Sol, D. |
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Title |
Behavioural flexibility: a neglected issue in the ecological and evolutionary literature |
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2003 |
Publication |
Animal innovation. |
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63-82 |
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Oxford University Press |
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Oxford |
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S. M. Reader and K. N. Laland |
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Equine Behaviour @ team @ |
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6532 |
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Author |
Lee, P.C. |
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Title |
Innovation as a behavioural response to environmental challenges |
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2003 |
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Animal Innovation |
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261-279 |
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Oxford University Press |
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Oxford |
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S. M. Reader and K. N. Laland |
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Equine Behaviour @ team @ |
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6534 |
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