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Author |
Matzke, S.M.; Oubre, J.L.; Caranto, G.R.; Gentry, M.K.; Galbicka, G. |
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Title |
Behavioral and immunological effects of exogenous butyrylcholinesterase in rhesus monkeys |
Type |
Journal Article |
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Year |
1999 |
Publication |
Pharmacology, Biochemistry, and Behavior |
Abbreviated Journal |
Pharmacol Biochem Behav |
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Volume |
62 |
Issue |
3 |
Pages |
523-530 |
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Keywords |
Animals; Antibody Formation/drug effects; Behavior, Animal/*drug effects; Butyrylcholinesterase/*immunology/pharmacokinetics/*pharmacology; Cognition/drug effects; Color Perception/drug effects; Conditioning, Operant/drug effects; Discrimination Learning/drug effects; Half-Life; Horses; Humans; Macaca mulatta; Male |
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Abstract |
Although conventional therapies prevent organophosphate (OP) lethality, laboratory animals exposed to such treatments typically display behavioral incapacitation. Pretreatment with purified exogenous human or equine serum butyrylcholinesterase (Eq-BuChE), conversely, has effectively prevented OP lethality in rats and rhesus monkeys, without producing the adverse side effects associated with conventional treatments. In monkeys, however, using a commercial preparation of Eq-BuChE has been reported to incapacitate responding. In the present study, repeated administration of commercially prepared Eq-BuChE had no systematic effect on behavior in rhesus monkeys as measured by a six-item serial probe recognition task, despite 7- to 18-fold increases in baseline BuChE levels in blood. Antibody production induced by the enzyme was slight after the first injection and more pronounced following the second injection. The lack of behavioral effects, the relatively long in vivo half-life, and the previously demonstrated efficacy of BuChE as a biological scavenger for highly toxic OPs make BuChE potentially more effective than current treatment regimens for OP toxicity. |
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Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA |
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0091-3057 |
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PMID:10080246 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4064 |
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Author |
Dunbar, K.; MacLeod, C.M. |
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Title |
A horse race of a different color: Stroop interference patterns with transformed words |
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Journal Article |
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Year |
1984 |
Publication |
Journal of Experimental Psychology. Human Perception and Performance |
Abbreviated Journal |
J Exp Psychol Hum Percept Perform |
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Volume |
10 |
Issue |
5 |
Pages |
622-639 |
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Keywords |
*Attention; *Color Perception; Discrimination Learning; Humans; Orientation; Reaction Time; Reading; *Semantics |
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Abstract |
Four experiments investigated Stroop interference using geometrically transformed words. Over experiments, reading was made increasingly difficult by manipulating orientation uncertainty and the number of noncolor words. As a consequence, time to read color words aloud increased dramatically. Yet, even when reading a color word was considerably slower than naming the color of ink in which the word was printed, Stroop interference persisted virtually unaltered. This result is incompatible with the simple horse race model widely used to explain color-word interference. When reading became extremely slow, a reversed Stroop effect--interference in reading the word due to an incongruent ink color--appeared for one transformation together with the standard Stroop interference. Whether or not the concept of automaticity is invoked, relative speed of processing the word versus the color does not provide an adequate overall explanation of the Stroop phenomenon. |
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0096-1523 |
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PMID:6238123 |
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Equine Behaviour @ team @ |
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4065 |
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Author |
Wolfe, J.M. |
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Title |
Hidden visual processes |
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Journal Article |
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Year |
1983 |
Publication |
Scientific American |
Abbreviated Journal |
Sci Am |
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Volume |
248 |
Issue |
2 |
Pages |
94-103 |
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Keywords |
Color Perception/*physiology; Humans; Motion Perception/physiology; Ocular Physiology; Vision; Visual Perception/*physiology |
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Abstract |
Isoluminant stimulus is an image whose edges are defined only by a change in color, not by change in brightness. The stimulus here is imperfect: the blue parts and the green parts of the image are only as nearly equal in brightness as they can be on the printed page. Moreover, the change in brightness beyond the edge of the page is apparent, and so is the fact that the reader is holding the magazine at reading distance. When such cues are removed under laboratory conditions, subjects faced with an isoluminant stimulus prove unable to bring its edges into focus. This deficiency contributes to making a familiar face hard to recognize. The experiment indicates that the brain process underlying visual accommodation (the focusing of the eyes) cannot “see” color; it is a hidden process distinct from the processes that lead to perception. The image shows Groucho Marx as he appeared in the motion picture Horse Feathers. |
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0036-8733 |
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Notes |
PMID:6836258 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4066 |
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Author |
Salzen, E.A.; Cornell, J.M. |
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Title |
Self-perception and species recognition in birds |
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Journal Article |
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Year |
1968 |
Publication |
Behaviour |
Abbreviated Journal |
Behaviour |
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Volume |
30 |
Issue |
1 |
Pages |
44-65 |
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Keywords |
Animals; Birds; Color Perception; Discrimination Learning; Generalization, Response; Imprinting (Psychology); *Perception; *Self Concept; Social Isolation; *Species Specificity; Water |
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0005-7959 |
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PMID:5644775 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4154 |
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Author |
Griffin, B. |
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Title |
The use of fecal markers to facilitate sample collection in group-housed cats |
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Journal Article |
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Year |
2002 |
Publication |
Contemporary Topics in Laboratory Animal Science / American Association for Laboratory Animal Science |
Abbreviated Journal |
Contemp Top Lab Anim Sci |
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Volume |
41 |
Issue |
2 |
Pages |
51-56 |
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Keywords |
Animals; Behavior, Animal; Biological Markers/*analysis; Cats/*physiology/psychology; Diet/veterinary; Feces/*chemistry; Food Coloring Agents/analysis; Housing, Animal; Individuality; Plastics/analysis; Specimen Handling/methods/*veterinary |
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Abstract |
The provision of proper social housing is a priority when designing an experiment using domestic cats as laboratory animals. When animals are group-housed, studies requiring analysis of stool samples from individual subjects pose difficulty in sample collection and identification. In this study, commercially available concentrated food colorings (known as bakers pastes) were used as fecal markers in group-housed cats. Cats readily consumed 0.5 ml of bakers paste food coloring once daily in canned cat food. Colorings served as fecal markers by imparting a distinct color to each cat s feces, allowing identification in the litter box. In addition, colored glitter (1/8 teaspoon in canned food) was fed to cats and found to be a reliable fecal marker. Long-term feeding of colorings and glitter was found to be safe and effective at yielding readily identifiable stools. |
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Scott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Alabama 36841, USA |
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1060-0558 |
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PMID:11958604 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4165 |
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