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Author |
Goodloe, R.B |
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Title |
Population characteristics of feral horses on Cumberland Island, Georgia and their management implications |
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Year |
2000 |
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Journal of Wildlife Management |
Abbreviated Journal |
J Wildl Manag |
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64 |
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1 |
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114-121 |
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937-2817 |
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Equine Behaviour @ team @ |
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2296 |
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Author |
Roels, S.; Tilmant, K.; Van Daele, A.; Van Marck, E.; Ducatelle, R. |
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Title |
Proliferation, DNA ploidy, p53 overexpression and nuclear DNA fragmentation in six equine melanocytic tumours |
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Journal Article |
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Year |
2000 |
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Journal of Veterinary Medicine, Series A |
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47 |
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439-438 |
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refbase @ user @ |
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2016 |
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Author |
Miyashita, Y.; Nakajima, S.; Imada, H. |
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Title |
Differential outcome effect in the horse. |
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Journal Article |
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Year |
2000 |
Publication |
Journal of the Experimental Analysis of Behavior |
Abbreviated Journal |
J Exp Anal Behav |
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Volume |
74 |
Issue |
2 |
Pages |
245-253. |
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Abstract |
hree horses were trained with a discrimination task in which the color (blue or yellow) of a center panel signaled the correct (left or right) response (lever press). Reinforcing outcomes for the two correct color-position combinations (blue-left and yellow-right) were varied across phases. Discrimination performance was better when the combinations were differentially reinforced by two types of food (chopped carrot pieces and a solid food pellet) than when the combinations were randomly reinforced by these outcomes or when there was a common reinforcer for each of the correct combinations. However, the discrimination performance established by the differential outcome procedure was still 80% to 90% correct, and an analysis of two-trial sequences revealed that the stimulus color of the preceding trial interfered with discrimination performance on a given trial. Our demonstration of the differential outcome effect in the horse and its further analysis might contribute to more efficient control of equine behavior in the laboratory as well as in horse sports. |
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Equine Behaviour @ team @ |
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3579 |
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Author |
Miller, R.M. |
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Title |
The revolution in horsemanship |
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Journal Article |
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Year |
2000 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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216 |
Issue |
8 |
Pages |
1232-1233 |
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Keywords |
*Animal Welfare; Animals; *Behavior, Animal; *Bonding, Human-Pet; *Horses/psychology; Humans; *Physical Conditioning, Animal |
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0003-1488 |
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PMID:10767957 |
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no |
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refbase @ user @ |
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1925 |
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Author |
Madigan, J.E.; Whittemore, J. |
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Title |
The role of the equine practitioner in disasters |
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Journal Article |
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Year |
2000 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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216 |
Issue |
8 |
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1238-1239 |
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*Animal Husbandry/education; *Animal Welfare; Animals; Disaster Planning; *Horses; *Natural Disasters; United States; *Veterinary Medicine |
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Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis 95616, USA |
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0003-1488 |
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PMID:10767959 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4055 |
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Author |
Hagen, S.J.; Eaton, W.A. |
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Title |
Two-state expansion and collapse of a polypeptide |
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Journal Article |
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Year |
2000 |
Publication |
Journal of Molecular Biology |
Abbreviated Journal |
J Mol Biol |
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301 |
Issue |
4 |
Pages |
1019-1027 |
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Animals; Computer Simulation; Cytochrome c Group/*chemistry/*metabolism; Horses; Kinetics; Lasers; Models, Chemical; Peptides/*chemistry/*metabolism; Protein Conformation; Protein Denaturation; *Protein Folding; Spectrometry, Fluorescence; Temperature; Thermodynamics |
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Abstract |
The initial phase of folding for many proteins is presumed to be the collapse of the polypeptide chain from expanded to compact, but still denatured, conformations. Theory and simulations suggest that this collapse may be a two-state transition, characterized by barrier-crossing kinetics, while the collapse of homopolymers is continuous and multi-phasic. We have used a laser temperature-jump with fluorescence spectroscopy to measure the complete time-course of the collapse of denatured cytochrome c with nanosecond time resolution. We find the process to be exponential in time and thermally activated, with an apparent activation energy approximately 9 k(B)T (after correction for solvent viscosity). These results indicate that polypeptide collapse is kinetically a two-state transition. Because of the observed free energy barrier, the time scale of polypeptide collapse is dramatically slower than is predicted by Langevin models for homopolymer collapse. |
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Address |
Laboratory of Chemical Physics, NIDDK, National Institutes of Health, Building 5, Bethesda, MD, 20892-0520, USA |
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0022-2836 |
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PMID:10966803 |
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Equine Behaviour @ team @ |
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3790 |
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Author |
Pierce, M.M.; Nall, B.T. |
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Title |
Coupled kinetic traps in cytochrome c folding: His-heme misligation and proline isomerization |
Type |
Journal Article |
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Year |
2000 |
Publication |
Journal of Molecular Biology |
Abbreviated Journal |
J Mol Biol |
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Volume |
298 |
Issue |
5 |
Pages |
955-969 |
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Keywords |
Amino Acid Sequence; Amino Acid Substitution/genetics; Binding Sites; Cytochrome c Group/*chemistry/genetics/*metabolism; *Cytochromes c; Enzyme Stability/drug effects; Fluorescence; Guanidine/pharmacology; Heme/*metabolism; Histidine/genetics/*metabolism; Hydrogen-Ion Concentration; Isomerism; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation/genetics; Proline/*chemistry/metabolism; Protein Conformation/drug effects; Protein Denaturation/drug effects; *Protein Folding; Protein Renaturation; Saccharomyces cerevisiae/enzymology/genetics; Sequence Alignment; Thermodynamics |
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Abstract |
The effect of His-heme misligation on folding has been investigated for a triple mutant of yeast iso-2 cytochrome c (N26H,H33N,H39K iso-2). The variant contains a single misligating His residue at position 26, a location at which His residues are found in several cytochrome c homologues, including horse, tuna, and yeast iso-1. The amplitude for fast phase folding exhibits a strong initial pH dependence. For GdnHCl unfolded protein at an initial pH<5, the observed refolding at final pH 6 is dominated by a fast phase (tau(2f)=20 ms, alpha(2f)=90 %) that represents folding in the absence of misligation. For unfolded protein at initial pH 6, folding at final pH 6 occurs in a fast phase of reduced amplitude (alpha(2f) approximately 20 %) but the same rate (tau(2f)=20 ms), and in two slower phases (tau(m)=6-8 seconds, alpha(m) approximately 45 %; and tau(1b)=16-20 seconds, alpha(1b) approximately 35 %). Double jump experiments show that the initial pH dependence of the folding amplitudes results from a slow pH-dependent equilibrium between fast and slow folding species present in the unfolded protein. The slow equilibrium arises from coupling of the His protonation equilibrium to His-heme misligation and proline isomerization. Specifically, Pro25 is predominantly in trans in the unligated low-pH unfolded protein, but is constrained in a non-native cis isomerization state by His26-heme misligation near neutral pH. Refolding from the misligated unfolded form proceeds slowly due to the large energetic barrier required for proline isomerization and displacement of the misligated His26-heme ligand. |
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Center for Biomolecular Structure, Department of Biochemistry, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA |
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0022-2836 |
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PMID:10801361 |
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refbase @ user @ |
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3853 |
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Author |
Zentall, T.R.; Kaiser, D.H.; Clement, T.S.; Weaver, J.E.; Campbell, G. |
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Title |
Presence/absence-sample matching by pigeons: divergent retention functions may result from the similarity of behavior during the absence sample and the retention interval |
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Journal Article |
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Year |
2000 |
Publication |
Journal of experimental psychology. Animal behavior processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
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Volume |
26 |
Issue |
3 |
Pages |
294-304 |
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Keywords |
Analysis of Variance; Animals; *Behavior, Animal; *Choice Behavior; *Columbidae; *Conditioning, Operant; Cues |
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Divergent choose-absence retention functions typically found in pigeons following presence/absence-sample matching have been attributed to the development of a single-code/default coding strategy. However, such effects may result from adventitious differential responding to the samples. In Experiment 1, retention functions were divergent only when differential sample responding could serve as the basis for comparison choice. In Experiment 2, when pecking did not occur during the retention interval, a choose-absence bias was found, but when pecking occurred during the retention interval, a choose-presence bias resulted. In Experiment 3, positive transfer was found when a stimulus associated with the absence of pecking replaced the absence sample but not when a stimulus associated with pecking replaced the presence sample. Thus, presence/absence-sample matching may not encourage the development of a single-code/default coding strategy in pigeons. |
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Department of Psychology, University of Kentucky, Lexington 40506, USA. zentall@pop.uky.edu |
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0097-7403 |
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PMID:10913994 |
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refbase @ user @ |
Serial |
247 |
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Author |
Tommasi, L.; Vallortigara, G. |
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Title |
Searching for the center: spatial cognition in the domestic chick (Gallus gallus) |
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Journal Article |
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Year |
2000 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
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Volume |
26 |
Issue |
4 |
Pages |
477-486 |
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Keywords |
Animals; Behavior, Animal/physiology; Chickens; Cognition/*physiology; Learning/physiology; Male; Space Perception/*physiology; Spatial Behavior/*physiology |
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Abstract |
Chicks learned to find food hidden under sawdust by ground-scratching in the central position of the floor of a closed arena. When tested inan arena of identical shape but a larger area, chicks searched at 2 different locations, one corresponding to the correct distance (i.e., center) in the smaller (training) arena and the other to the actual center of the test arena. When tested in an arena of the same shape but a smaller area, chicks searched in the center of it. These results suggest that chicks are able to encode information on the absolute and relative distance of the food from the walls of the arena. After training in the presence of a landmark located at the center of the arena, animals searched at the center even after the removal of the landmark. Marked changes in the height of the walls of the arena produced some displacement in searching behavior, suggesting that chicks used the angular size of the walls to estimate distances. |
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Department of General Psychology, University of Padua, Italy |
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0097-7403 |
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PMID:11056887 |
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Equine Behaviour @ team @ |
Serial |
2774 |
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Author |
Brannon, E.M.; Terrace, H.S. |
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Title |
Representation of the numerosities 1-9 by rhesus macaques (Macaca mulatta) |
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Journal Article |
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Year |
2000 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
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26 |
Issue |
1 |
Pages |
31-49 |
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Animals; *Cognition; Macaca mulatta/*psychology; *Mathematics; Perception; Reaction Time |
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Three rhesus monkeys (Macaca mulatta) were trained to respond to exemplars of 1, 2, 3, and 4 in an ascending, descending, or a nonmonotonic numerical order (1-->2-->3-->4, 4-->3-->2--1, 3-->1-->4-->2). The monkeys were then tested on their ability to order pairs of the novel numerosities 5-9. In Experiment 1, all 3 monkeys ordered novel exemplars of the numerosities 1-4 in ascending or descending order. The attempt to train a nonmonotonic order (3-->1-->4-->2) failed. In Experiment 2A, the 2 monkeys who learned the ascending numerical rule ordered pairs of the novel numerosities 5-9 on unreinforced trials. The monkey who learned the descending numerical rule failed to extrapolate the descending rule to new numerosities. In Experiment 2B all 3 monkeys ordered novel exemplars of pairs of the numerosities 5-9. Accuracy and latency of responding revealed distance and magnitude effects analogous to previous findings with human participants (R. S. Moyer & T. K. Landaeur, 1967). Collectively these studies show that monkeys represent the numerosities 1-9 on at least an ordinal scale. |
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Department of Psychology, Columbia University, New York, New York 10027, USA. liz@psych.columbia.edu |
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0097-7403 |
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PMID:10650542 |
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Equine Behaviour @ team @ |
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2775 |
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