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Author |
Marc, M.; Parvizi, N.; Ellendorff, F.; Kallweit, E.; Elsaesser, F. |
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Title |
Plasma cortisol and ACTH concentrations in the warmblood horse in response to a standardized treadmill exercise test as physiological markers for evaluation of training status |
Type |
Journal Article |
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Year |
2000 |
Publication |
Journal of Animal Science |
Abbreviated Journal |
J. Anim Sci. |
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Volume |
78 |
Issue |
7 |
Pages |
1936-1946 |
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Keywords |
Adrenocorticotropic Hormone/*blood/diagnostic use; Animals; Catheterization/veterinary; Exercise Test; Horses/*blood; Hydrocortisone/*blood; Male; *Physical Conditioning, Animal |
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Abstract |
Reliable physiological markers for performance evaluation in sport horses are missing. To determine the diagnostic value of plasma ACTH and cortisol measurements in the warmblood horse, 10 initially 3-yr-old geldings of the Hannovarian breed were either exposed to a training schedule or served as controls. During experimental Phase 1, horses were group-housed, and half of the horses were trained for 20 wk on a high-speed treadmill. During Phase 2, groups were switched and one group was trained for 10 wk as during Phase 1, whereas the control group was confined to boxes. During Phase 3 horses were initially schooled for riding. Thereafter, all horses were regularly schooled for dressage and jumping, and half of the horses received an additional endurance training for 24 wk. During all phases horses were exposed at regular intervals to various standardized treadmill exercise tests. During and after the tests frequent blood samples were taken from an indwelling jugular catheter for determination of ACTH and cortisol. Treadmill exercise increased both hormones. Maximum ACTH concentrations were recorded at the end of exercise, and maximum cortisol levels were recorded 20 to 30 min later. Except for one test there were no differences in ACTH levels between trained horses and controls. There was no significant effect of training on the cortisol response (net increase) to treadmill exercise in any of the tests during Phase 1. During Phase 2 higher cortisol responses were recorded in controls than in trained horses (P < .05) after 10 wk of training (controls confined to boxes). During Phase 3 plasma cortisol responses were also higher in controls than in trained horses (P < .05 after 6, 18, and 24, P < or = .07 after 12 wk of training) when the inclination of the treadmill was 5%, but not at 3%. There was no overlap in net cortisol responses at 30 min between trained and untrained horses. An ACTH application after 24 wk of training resulted in higher cortisol responses in controls than in trained horses (P < or = .05), without any overlap between the groups at 30 min after ACTH. Plasma cortisol responses to either treadmill exercise or ACTH injection may be a reliable physiological marker for performance evaluation. Prerequisites are sufficient differences in training status and sufficient intensity of exercise test conditions. |
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Institute of Animal Science and Animal Behaviour, Federal Agricultural Research Center (FAL) Mariensee, Neustadt, Germany |
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0021-8812 |
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PMID:10907837 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3732 |
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Author |
Ferguson, D.L.; Rosales-Ruiz, J. |
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Title |
Loading the problem loader: the effects of target training and shaping on trailer-loading behavior of horses |
Type |
Journal Article |
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Year |
2001 |
Publication |
Journal of Applied Behavior Analysis |
Abbreviated Journal |
J Appl Behav Anal |
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Volume |
34 |
Issue |
4 |
Pages |
409-423 |
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Keywords |
Animals; *Conditioning, Operant; *Escape Reaction; Female; Horses/*psychology; Reinforcement (Psychology); *Transportation |
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Abstract |
The purpose of this study was to develop an effective method for trailer loading horses based on principles of positive reinforcement. Target training and shaping were used to teach trailer-loading behavior to 5 quarter horse mares in a natural setting. All 5 had been trailer loaded before through the use of aversive stimulation. Successive approximations to loading and inappropriate behaviors were the dependent variables. After training a horse to approach a target, the target was moved to various locations inside the trailer. Horses started training on the left side of a two-horse trailer. After a horse was loading on the left side, she was moved to the right side, then to loading half on the right and half on the left. A limited-hold procedure and the presence of a companion horse seemed to facilitate training for 1 horse. Inappropriate behaviors fell to zero immediately after target training, and all the horses successfully completed the shaping sequence. Finally, these effects were observed to generalize to novel conditions (a different trainer and a different trailer). |
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University of North Texas, Denton 76203, USA |
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0021-8855 |
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Notes |
PMID:11800182 |
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no |
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Call Number |
refbase @ user @ |
Serial |
1915 |
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Author |
Gavrilova, O.; Haluzik, M.; Matsusue, K.; Cutson, J.J.; Johnson, L.; Dietz, K.R.; Nicol, C.J.; Vinson, C.; Gonzalez, F.J.; Reitman, M.L. |
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Title |
Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass |
Type |
Journal Article |
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Year |
2003 |
Publication |
The Journal of biological chemistry |
Abbreviated Journal |
J Biol Chem |
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Volume |
278 |
Issue |
36 |
Pages |
34268-34276 |
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Keywords |
Adipose Tissue/*metabolism; Animals; Blotting, Southern; Blotting, Western; Female; Hypoglycemia/genetics; Insulin Resistance/genetics; Lipid Metabolism; Liver/*metabolism; Liver Diseases/genetics/*metabolism; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; RNA/metabolism; Receptors, Cytoplasmic and Nuclear/*genetics/*physiology; Recombination, Genetic; Thiazoles/pharmacology; *Thiazolidinediones; Time Factors; Transcription Factors/*genetics/*physiology; Triglycerides/*metabolism |
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Abstract |
Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor that mediates the antidiabetic effects of thiazolidinediones. PPAR gamma is present in adipose tissue and becomes elevated in fatty livers, but the roles of specific tissues in thiazolidinedione actions are unclear. We studied the function of liver PPAR gamma in both lipoatrophic A-ZIP/F-1 (AZIP) and wild type mice. In AZIP mice, ablation of liver PPAR gamma reduced the hepatic steatosis but worsened the hyperlipidemia, triglyceride clearance, and muscle insulin resistance. Inactivation of AZIP liver PPAR gamma also abolished the hypoglycemic and hypolipidemic effects of rosiglitazone, demonstrating that, in the absence of adipose tissue, the liver is a primary and major site of thiazolidinedione action. In contrast, rosiglitazone remained effective in non-lipoatrophic mice lacking liver PPAR gamma, suggesting that adipose tissue is the major site of thiazolidinedione action in typical mice with adipose tissue. Interestingly, mice without liver PPAR gamma, but with adipose tissue, developed relative fat intolerance, increased adiposity, hyperlipidemia, and insulin resistance. Thus, liver PPAR gamma regulates triglyceride homeostasis, contributing to hepatic steatosis, but protecting other tissues from triglyceride accumulation and insulin resistance. |
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Address |
Diabetes Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. oksanag@bdg10.niddk.nih.gov |
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English |
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ISSN |
0021-9258 |
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Notes |
PMID:12805374 |
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no |
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Call Number |
refbase @ user @ |
Serial |
81 |
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Author |
Thor, D.H.; Holloway, W.R. |
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Title |
Social memory of the male laboratory rat |
Type |
Journal Article |
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Year |
1982 |
Publication |
Journal of Comparative and Physiological Psychology |
Abbreviated Journal |
J. Comp. Physiol. Psychol. |
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Volume |
96 |
Issue |
6 |
Pages |
1000-1006 |
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Keywords |
duration of social-investigatory behavior, measure of conspecific recognition &; social memory, male rats |
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Abstract |
Used duration of social-investigatory behavior by 36 mature male Long-Evans rats as a measure of individual recognition in 5 experiments to assess social memory. In Exp I, the duration of social investigation during a 2nd exposure to the same juvenile (n[en space]=[en space]12) was directly related to the length of the interexposure interval. In Exp II, Ss were exposed to the same or different juvenile 10 min after an initial 5-min exposure to a novel juvenile; reexposure to the same juvenile elicited significantly less social investigation than an exposure to a different juvenile. Exps III and IV demonstrated that following a 5-min introductory exposure, social memory of the juvenile was relatively brief in comparison with that of mature Ss. Exp V revealed a retroactive interference effect on recently acquired memory for an individual: 12 mature Ss exposed to interpolated social experience engaged in significantly longer investigation of a juvenile than those with no interpolated social experience. The combined results suggest that (1) the rat normally engages in spontaneous learning of individual identity and (2) social memory may be a significant aspect of complex social interactions. (16 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved) |
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ISSN |
0021-9940 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
5133 |
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Author |
Blunden, A.S.; Smith, K.C.; Whitwell, K.E.; Dunn, K.A. |
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Title |
Systemic infection by equid herpesvirus-1 in a Grevy's zebra stallion (Equus grevyi) with particular reference to genital pathology |
Type |
Journal Article |
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Year |
1998 |
Publication |
Journal of Comparative Pathology |
Abbreviated Journal |
J Comp Pathol |
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Volume |
119 |
Issue |
4 |
Pages |
485-493 |
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Keywords |
Animals; Animals, Zoo; Epididymis/pathology/virology; Equidae/*virology; Herpesviridae Infections/diagnosis/pathology/*veterinary; Herpesvirus 1, Equid/isolation & purification/*pathogenicity; Lymph Nodes/pathology/virology; Male; Nasal Mucosa/pathology/virology; Pulmonary Edema/pathology; Spleen/virology; Testis/*pathology/virology |
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Abstract |
A severe multi-systemic form of equid herpesvirus-1 infection is described in an adult zebra stallion. There was multifocal necrotizing rhinitis, marked hydrothorax and pulmonary oedema, with viral antigen expression in degenerating epithelial cells, local endothelial cells and intravascular leucocytes of the nasal mucosa and lung. Specific localization of EHV-1 infection was seen in the testes and epididymides, including infection of Leydig cells and germinal epithelium, which would have facilitated venereal shedding of virus in life. The case provided a unique opportunity to study hitherto undescribed aspects of the pathogenesis of naturally occurring EHV-1 infection in the male equine genital tract. Restriction digests of the isolate demonstrated a pattern similar to that of EHV-1 isolates previously recovered from aborted zebra and onager fetuses. |
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Address |
Animal Health Trust Centre for Preventive Medicine, Newmarket, Suffolk, UK |
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English |
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ISSN |
0021-9975 |
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Notes |
PMID:9839210 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2239 |
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Author |
Kirkpatrick, J.F.; Wiesner, L.; Kenney, R.M.; Ganjam, V.K.; Turner, J.W. |
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Title |
Seasonal variation in plasma androgens and testosterone in the North American wild horse |
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Journal Article |
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Year |
1977 |
Publication |
The Journal of endocrinology |
Abbreviated Journal |
J Endocrinol |
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Volume |
72 |
Issue |
2 |
Pages |
237-238 |
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Keywords |
Androgens/*blood; Animals; Horses/*blood; Male; *Seasons; Testosterone/*blood |
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English |
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ISSN |
0022-0795 |
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Notes |
PMID:845536 |
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no |
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Call Number |
refbase @ user @ |
Serial |
148 |
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Author |
Arnold, W.; Ruf, T.; Kuntz, R. |
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Title |
Seasonal adjustment of energy budget in a large wild mammal, the Przewalski horse (Equus ferus przewalskii) II. Energy expenditure |
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Journal Article |
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Year |
2006 |
Publication |
The Journal of experimental biology |
Abbreviated Journal |
J Exp Biol |
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Volume |
209 |
Issue |
Pt 22 |
Pages |
4566-4573 |
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Keywords |
Animals; Animals, Wild/*physiology; Body Temperature; Body Temperature Regulation; Eating; *Energy Metabolism; Female; Heart Rate; Horses/*physiology; Male; Motor Activity; Pregnancy; Reproduction; *Seasons |
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Abstract |
Many large mammals show pronounced seasonal fluctuations of metabolic rate (MR). It has been argued, based on studies in ruminants, that this variation merely results from different levels of locomotor activity (LA), and heat increment of feeding (HI). However, a recent study in red deer (Cervus elaphus) identified a previously unknown mechanism in ungulates--nocturnal hypometabolism--that contributed significantly to reduced energy expenditure, mainly during late winter. The relative contribution of these different mechanisms to seasonal adjustments of MR is still unknown, however. Therefore, in the study presented here we quantified for the first time the independent contribution of thermoregulation, LA and HI to heart rate (f(H)) as a measure of MR in a free-roaming large ungulate, the Przewalski horse or Takhi (Equus ferus przewalskii Poljakow). f(H) varied periodically throughout the year with a twofold increase from a mean of 44 beats min(-1) during December and January to a spring peak of 89 beats min(-1) at the beginning of May. LA increased from 23% per day during December and January to a mean level of 53% per day during May, and declined again thereafter. Daily mean subcutaneous body temperature (T(s)) declined continuously during winter and reached a nadir at the beginning of April (annual range was 5.8 degrees C), well after the annual low of air temperature and LA. Lower T(s) during winter contributed considerably to the reduction in f(H). In addition to thermoregulation, f(H) was affected by reproduction, LA, HI and unexplained seasonal variation, presumably reflecting to some degree changes in organ mass. The observed phase relations of seasonal changes indicate that energy expenditure was not a consequence of energy uptake but is under endogenous control, preparing the organism well in advance of seasonal energetic demands. |
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Address |
Research Institute of Wildlife Ecology, University of Veterinary Medicine, Vienna, Savoyenstrasse 1, 1160 Vienna, Austria. walter.arnold@vu-wien.ac.at |
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0022-0949 |
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Notes |
PMID:17079726 |
Approved |
no |
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Call Number |
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Serial |
1782 |
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Author |
Zentall, S.S.; Zentall, T.R.; Barack, R.C. |
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Title |
Distraction as a function of within-task stimulation for hyperactive and normal children |
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Journal Article |
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Year |
1978 |
Publication |
Journal of learning disabilities |
Abbreviated Journal |
J Learn Disabil |
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Volume |
11 |
Issue |
9 |
Pages |
540-548 |
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Keywords |
*Attention; Child; Child, Preschool; Color Perception; Female; Humans; Hyperkinesis/*psychology; Male; Motor Skills; *Task Performance and Analysis; Visual Perception |
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0022-2194 |
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Notes |
PMID:731119 |
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no |
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Call Number |
refbase @ user @ |
Serial |
270 |
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Author |
Strickman, D. |
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Title |
Notes on Tabanidae (Diptera) from Paraguay |
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Journal Article |
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Year |
1982 |
Publication |
Journal of Medical Entomology |
Abbreviated Journal |
J Med Entomol |
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Volume |
19 |
Issue |
4 |
Pages |
399-402 |
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Keywords |
Animals; Cattle; Diptera/*growth & development; Dogs; Ecology; Female; Geography; Horses; Humans; Insect Bites and Stings/epidemiology/veterinary; Male; Paraguay |
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0022-2585 |
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Notes |
PMID:7154018 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2690 |
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Author |
Nelson, W.A.; Keirans, J.E.; Bell, J.F.; Clifford, C.M. |
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Title |
Host-ectoparasite relationships |
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Journal Article |
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Year |
1975 |
Publication |
Journal of Medical Entomology |
Abbreviated Journal |
J Med Entomol |
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12 |
Issue |
2 |
Pages |
143-166 |
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Keywords |
Animal Nutrition Physiology; Animals; Anoplura/physiology; *Arthropods; Birds/parasitology; Chickens/parasitology; Dermacentor/parasitology; Diptera; Ecology; Feeding Behavior; Female; Horses/parasitology; Humans; Male; Mallophaga/physiology; Mice/parasitology; Mites/physiology; Reproduction; Sarcoptes scabiei/physiology; Sheep/parasitology; Skin/parasitology; Ticks/physiology; Toxins, Biological/toxicity; Trombiculidae/physiology |
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English |
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0022-2585 |
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Notes |
PMID:808617 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2704 |
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