| |
Records |
Links |
|
Author |
Baudry, L.; Leroy, D.; Chollet, D. |
|
| |
Title |
The effect of combined self- and expert-modelling on the performance of the double leg circle on the pommel horse |
Type |
|
| |
Year |
2006 |
Publication |
Journal of Sports Sciences |
Abbreviated Journal |
J Sports Sci |
|
| |
Volume |
24 |
Issue |
10 |
Pages |
1055-1063 |
|
| |
Keywords |
Adolescent; Analysis of Variance; Child; *Expert Testimony; Feedback; Gymnastics/*physiology; Humans; *Leg/physiology; Movement/physiology; Physical Education and Training; Posture/physiology; Range of Motion, Articular/physiology; Retention (Psychology); *Video Recording |
|
| |
Abstract |
In this study, we investigated whether video modelling can enhance gymnasts' performance of the circle on a pommel horse. The procedure associated expert-modelling with self-modelling and quantitative performance analysis. Sixteen gymnasts were randomly assigned to one of two groups: (1) a modelling group, which received expert- and self-modelling, and performance feedback, or (2) a control group, which received no feedback. After five sessions of training, an analysis of variance with repeated measures indicated that the gains in the back, entry, front, and exit phases of the circle were greater for the modelling group than for the control group. During the training sessions, the gymnasts in the modelling group improved their body segmental alignment during the back phase more quickly than during the other phases. As predicted, although both groups performed the same number of circles (300 in 5 days, with 10 sequences of 6 circles), the modelling group improved their body segmental alignment more than the control group. It thus appears that immediate video modelling can help to correct complex sports movements such as the circle performed on the pommel horse. However, its effectiveness seemed to be dependent on the complexity of the phase. |
|
| |
Address |
CETAPS Laboratory, UPRES EA 3832, Faculty of Sports Sciences, Rouen University, Mont-Saint Aignan, France. ludovic_baudry@yahoo.fr |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN  |
0264-0414 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:17115520 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
4026 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Munoz-Sanz, A. |
|
| |
Title |
[Christopher Columbus flu. A hypothesis for an ecological catastrophe] |
Type |
Journal Article |
| |
Year |
2006 |
Publication |
Enfermedades Infecciosas y Microbiologia Clinica |
Abbreviated Journal |
Enferm Infecc Microbiol Clin |
|
| |
Volume |
24 |
Issue |
5 |
Pages |
326-334 |
|
| |
Keywords |
Animals; Atlantic Islands; Birds; Chickens; Disease Outbreaks/*history; Disease Reservoirs; Disease Susceptibility; Ecology; Europe/ethnology; History, 15th Century; Horses; Humans; Indians, South American; Influenza A virus/classification/genetics/pathogenicity; Influenza in Birds/epidemiology/history/transmission/virology; Influenza, Human/epidemiology/*history/mortality/transmission; Models, Biological; Orthomyxoviridae Infections/epidemiology/history/veterinary/virology; Poultry Diseases/epidemiology/history/transmission/virology; Reassortant Viruses/genetics/pathogenicity; Species Specificity; Sus scrofa; Swine Diseases/history/transmission/virology; Terminology; West Indies/epidemiology |
|
| |
Abstract |
When Christopher Columbus and his men embarked on the second Colombian expedition to the New World (1493), the crew suffered from fever, respiratory symptoms and malaise. It is generally accepted that the disease was influenza. Pigs, horses and hens acquired in Gomera (Canary Islands) traveled in the same ship. The pigs may well have been the origin of the flu and the intermediary hosts for genetic recombination of other viral subtypes. The Caribbean archipelago had a large population of birds, the natural reservoir of the avian influenza virus. In this ecological scenario there was a concurrence of several biological elements that had never before coexisted in the New World: pigs, horses, the influenza virus and humans. We propose that birds are likely to have played an important role in the epidemiology of the flu occurring on the second Colombian trip, which caused a fatal demographic catastrophe, with an estimated mortality of 90% among the natives. |
|
| |
Address |
Unidad de Patologia Infecciosa, Hospital Universitario Infanta Cristina, Servicio Extremeno de Salud, Universidad de Extremadura, Badajoz, Espana. infectio@unex.es |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
Spanish |
Summary Language |
|
Original Title |
La gripe de Cristobal Colon. Hipotesis sobre una catastrofe ecologica |
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0213-005X |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:16762260 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2624 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Heitkamp, H.C.; Horstmann, T.; Hillgeris, D. |
|
| |
Title |
[Riding injuries and injuries due to handling horses in experienced riders] |
Type |
Journal Article |
| |
Year |
1998 |
Publication |
Der Unfallchirurg |
Abbreviated Journal |
Unfallchirurg |
|
| |
Volume |
101 |
Issue |
2 |
Pages |
122-128 |
|
| |
Keywords |
Adult; Animals; Athletic Injuries/*epidemiology/etiology/surgery; Cross-Sectional Studies; Female; Fractures, Bone/epidemiology/etiology/surgery; Germany/epidemiology; *Horses; Humans; Incidence; Male; Multiple Trauma/epidemiology/etiology/surgery; Risk Factors |
|
| |
Abstract |
A group of experienced riders who qualified for the German riding badge 9.5 years ago answered a questionnaire pertaining to injuries during jumping, dressage and cross-country riding, as well as handling the horse. During riding 69% of the persons had had 187 injuries and while handling the horse 52% had had 124 injuries. Fractures and contusions were the most-frequent injuries; most riding injuries were located in the upper extremities and shoulder while handling mainly in the hands and feet. The number of injuries was comparable in jumping, dressage or cross-country riding. The time engaged in jumping was about one-third of the other types of riding, but the injuries were more severe. While handling the horse the number of injuries relative to the time spent during the activity were higher but less complicated. No change in safety precautions had been implemented by 67% of the persons injured. The injury rate for equestrians is relatively low both in handling the horse and during riding. The frequent fractures and contusions may be reduced by following the required safety regulations. |
|
| |
Address |
Abteilung Sportmedizin, Universitat Tubingen |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
German |
Summary Language |
|
Original Title |
Reitverletzungen und Verletzungen beim Umgang mit Pferden bei erfahrenen Reitern |
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0177-5537 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:9553480 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
3735 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Lansade, L.; Bouissou, M.-F. |
|
| |
Title |
Reactivity to humans: A temperament trait of horses which is stable across time and situations |
Type |
Journal Article |
| |
Year |
2008 |
Publication |
Applied Animal Behaviour Science |
Abbreviated Journal |
Appl. Anim. Behav. Sci. |
|
| |
Volume |
114 |
Issue |
3-4 |
Pages |
492-508 |
|
| |
Keywords |
Horse; Equus caballus; Reactivity to humans; Temperament trait; Personality; Behavioural consistency |
|
| |
Abstract |
The aim of this study was to test the existence of a “reactivity-to-humans” trait which is stable over time and across situations. For this purpose, four test situations were repeated on the same animals at 8 months, 1.5 years (N = 110 horses) and 2.5 years of age (N = 54 horses). These situations involved a “familiar passive human test” during which a familiar person stayed motionless in the test pen, a “familiar active human test” and an “unfamiliar active human test” during which a familiar or unfamiliar person attempted to touch the horse, and a “halter-fitting and heart-rate measurement test”, during which the horse was haltered and equipped with a surcingle and then had its heart-rate measured. Many behavioural variables were recorded during the tests, and correlations between ages and variables measured during other situations were investigated. When correlations were found, we concluded that the variables corresponded to temperament traits which are stable over time and across situations. The horses tested were divided into four groups according to breed (Anglo-Arab and Welsh) and year of birth (2001 and 2002). Data for each group were analysed separately with Spearman rank correlations. Regarding stability over time, there was a strong correlation between ages in the frequency of licking/nibbling the passive human, the time taken by a familiar or unfamiliar person to touch the horse, and the time taken to fit a halter (e.g. the time taken to touch the horse's muzzle was significantly correlated between ages in 7 out of the 8 possible cases: 0.40 <= R <= 0.67). Regarding stability across situations, results indicate that the more frequently a horse sniffed, licked or nibbled a passive human, the easier it was for either a familiar or unfamiliar active human to touch and halter it. Moreover, a horse which could be touched easily by a familiar human could also be touched and haltered easily by an unfamiliar human. These behaviours, which are linked directly to humans, therefore indicate good stability over time and across situations. In conclusion, this stability suggests the existence of a “reactivity-to-humans” temperament trait, whether the human is passive or active, familiar or unfamiliar. When the animals do not have frequent contact with humans, this reactivity is stable over time and can be measured as early as 8 months of age using the behavioural variables cited above. |
|
| |
Address |
|
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
|
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0168-1591 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
|
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
4710 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Barwick, R.S.; Mohammed, H.O.; McDonough, P.L.; White, M.E. |
|
| |
Title |
Epidemiologic features of equine Leptospira interrogans of human significance |
Type |
Journal Article |
| |
Year |
1998 |
Publication |
Preventive Veterinary Medicine |
Abbreviated Journal |
Prev Vet Med |
|
| |
Volume |
36 |
Issue |
2 |
Pages |
153-165 |
|
| |
Keywords |
Animals; Horse Diseases/epidemiology/*microbiology; Horses/microbiology; Humans; *Leptospira interrogans; New York/epidemiology; Weil Disease/epidemiology/microbiology/*veterinary; Zoonoses/epidemiology/*microbiology |
|
| |
Abstract |
Leptospirosis is a zoonotic bacterial disease caused by Leptospira interrogans. There is a serologic evidence that horses are exposed to L. interrogans and, as a shedder of these organisms, can be a threat to humans. We examined risk factors associated with the risk of testing seropositive to three L. interrogans serovars (L. icterohaemorrhagiae, L. grippotyphosa, and L. canicola) in the horses of New York State, in order to understand the epidemiology of the disease and suggest strategies to control and prevent equine leptospirosis. To carry out this study, blood samples were collected from a random sample of 2551 horses and tested for the presence of antibodies to the above serovars using the microscopic agglutination test. Samples with a titer $100 were considered positive. Clinical and demographic data were collected on each horse, the farms' management practices and ecology. Logistic regression analysis was used to develop a multivariate indexing system and to identify factors significantly associated with the risk of leptospirosis. Four indices were developed based on the possible sources of exposure: rodent exposure index; wildlife exposure index; soil and water index; and management index. The soil and water index was significantly associated with the risk of exposure to all three serovars. Management was positively associated with L. icterohaemorrhagiae and L. canicola. Density of horses turned out together was positively associated with the risk of exposure to L. grippotyphosa. We concluded that indirect exposure of horses to L. interrogans through contaminated soil and water appears to be significantly associated with the risk of exposure to all three serovars. Management appears to play an important role in the exposure to L. interrogans. Modification of management practices might reduce the horses' risk of exposure and hopefully minimize the human hazards. |
|
| |
Address |
Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0167-5877 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:9762736 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2653 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Hemelrijk, C.K.; Wantia, J. |
|
| |
Title |
Individual variation by self-organisation |
Type |
Journal Article |
| |
Year |
2005 |
Publication |
Neuroscience and biobehavioral reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
|
| |
Volume |
29 |
Issue |
1 |
Pages |
125-136 |
|
| |
Keywords |
Aggression; Animals; Behavior, Animal/*physiology; Competitive Behavior/*physiology; Female; Humans; *Individuality; Male; Models, Psychological; Sex Characteristics; *Social Dominance; Time Factors |
|
| |
Abstract |
In this paper, we show that differences in dominance and spatial centrality of individuals in a group may arise through self-organisation. Our instrument is a model, called DomWorld, that represents two traits that are often found in animals, namely grouping and competing. In this model individual differences grow under the following conditions: (1) when the intensity of aggression increases and grouping becomes denser, (2) when the degree of sexual dimorphism in fighting power increases. In this case the differences among females compared to males grow too, (3) when, upon encountering another individual, the tendency to attack is 'obligate' and not conditional, namely 'sensitive to risks'. Results resemble phenomena described for societies of primates, mice, birds and pigs. |
|
| |
Address |
Theoretical Biology, University of Groningen, NN Haren, The Netherlands. hemelrij@ifi.unizh.ch |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0149-7634 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15652260 |
Approved |
no |
|
| |
Call Number |
refbase @ user @ |
Serial |
443 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Fabrega, H.J. |
|
| |
Title |
Making sense of behavioral irregularities of great apes |
Type |
Journal Article |
| |
Year |
2006 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
|
| |
Volume |
30 |
Issue |
8 |
Pages |
1260-73; discussion 1274-7 |
|
| |
Keywords |
Animals; Behavior/*physiology; Evolution; Hominidae/*physiology; Humans; Mental Disorders/*physiopathology; Neurosciences; *Psychopathology; Social Behavior |
|
| |
Abstract |
Psychopathology, mental illness, and psychiatric treatment are concepts relevant to modern medicine and medical psychology and replete with cumbersome intellectual and literary baggage. They bear the imprint of suppositions, world views, and general beliefs and values exemplified in the science, history, and general culture of Anglo European societies. The study in higher apes of phenomena addressed by such concepts raises conceptual dilemmas, usually termed speciesism and anthropomorphism, not unlike those encountered in comparative human studies of similar phenomena across cultures and historical periods, namely, ethnocentrism and anachronism. The authors' synthesis of literature and their analysis of the implications of higher ape psychopathology represent an epistemically compelling account that broadens the scope of the comparative study of behavioral irregularities, a topic that provides a different slant for examining challenging questions in evolutionary biology and primatology, such as cognition, self awareness, intentional behavior, culture and behavioral traditions, social intelligence, sickness and healing, and altruism. Theoretical and empirical study of this topic expands formulation and can help provide informative answers about human evolution as well as essential features of human psychiatric syndromes, with potential practical implications. The study of psychopathology of higher apes and other non human primates represents an appropriate focus for neuroscience and bio-behavioral sciences. |
|
| |
Address |
Department of Psychiatry and Anthropology, University of Pittsburgh, School of Medicine, 3811 Ohara Street, Pittsburgh, PA 15213, USA. hfabregajr@adelphia.net |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0149-7634 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:17079015 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2802 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Pickens, C.L.; Holland, P.C. |
|
| |
Title |
Conditioning and cognition |
Type |
Journal Article |
| |
Year |
2004 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
|
| |
Volume |
28 |
Issue |
7 |
Pages |
651-661 |
|
| |
Keywords |
Animals; Association Learning/physiology; Cognition/*physiology; Conditioning (Psychology)/*physiology; Discrimination Learning/physiology; Humans; Memory; Models, Psychological; Reinforcement (Psychology); Visual Perception/physiology |
|
| |
Abstract |
Animals' abilities to use internal representations of absent objects to guide adaptive behavior and acquire new information, and to represent multiple spatial, temporal, and object properties of complex events and event sequences, may underlie many aspects of human perception, memory, and symbolic thought. In this review, two classes of simple associative learning tasks that address these core cognitive capacities are discussed. The first set, including reinforcer revaluation and mediated learning procedures, address the power of Pavlovian conditioned stimuli to gain access, through learning, to representations of upcoming events. The second set of investigations concern the construction of complex stimulus representations, as illustrated in studies of contextual learning, the conjunction of explicit stimulus elements in configural learning procedures, and recent studies of episodic-like memory. The importance of identifying both cognitive process and brain system bases of performance in animal models is emphasized. |
|
| |
Address |
Department of Psychological and Brain Sciences, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0149-7634 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15555675 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2803 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Sarter, M. |
|
| |
Title |
Animal cognition: defining the issues |
Type |
Journal Article |
| |
Year |
2004 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
|
| |
Volume |
28 |
Issue |
7 |
Pages |
645-650 |
|
| |
Keywords |
Animals; Behavior, Animal/*physiology; Cognition/*physiology; Humans; *Models, Animal; Psychopharmacology/methods; Reproducibility of Results |
|
| |
Abstract |
The assessment of cognitive functions in rodents represents a critical experimental variable in many research fields, ranging from the basic cognitive neurosciences to psychopharmacology and neurotoxicology. The increasing use of animal behavioral tests as 'assays' for the assessment of effects on learning and memory has resulted in a considerable heterogeneity of data, particularly in the field of behavioral and psycho pharmacology. The limited predictive validity of changes in behavioral performance observed in standard animal tests of learning and memory indicates that a renewed effort to scrutinize the validity of these tests is warranted. In humans, levels of processing (effortful vs. automatic) and categories of information (procedural vs. episodic/declarative) are important variables of cognitive operations. The design of tasks that assess the recall of 'episodic' or 'declarative' information appears to represent a particular challenge for research using laboratory rodents. For example, the hypothesis that changes in inspection time for a previously encountered place or object are based on the recall of declarative/episodic information requires substantiation. In order to generalize findings on the effects of neuronal or pharmacological manipulations on learning and memory, obtained from one species and one task, to other species and other tasks, the mediating role of important sets of variables which influence learning and memory (e.g. attentional, affective) needs to be determined. Similar to the view that a neuronal manipulation (e.g. a lesion) represents a theory of the condition modeled (e.g. a degenerative disorder), an animal behavioral task represents a theory of the behavioral/cognitive process of interest. Therefore, the test of hypotheses regarding the validity of procedures used to assess cognitive functions in animals is an inherent part of the research process. |
|
| |
Address |
Department of Psychology, University of Michigan, 4032 East Hall, 525 E. University Avenue, Ann Arbor, MI 48109-1109, USA. msarter@umich.edu |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0149-7634 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:15555674 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2804 |
|
| Permanent link to this record |
| |
|
| |
|
Author |
Branchi, I.; Bichler, Z.; Berger-Sweeney, J.; Ricceri, L. |
|
| |
Title |
Animal models of mental retardation: from gene to cognitive function |
Type |
Journal Article |
| |
Year |
2003 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
|
| |
Volume |
27 |
Issue |
1-2 |
Pages |
141-153 |
|
| |
Keywords |
Animals; Animals, Genetically Modified/growth & development; Behavior/physiology; Behavior, Animal; Brain/*growth & development; Cognition/*physiology; *Disease Models, Animal; Environment; Genes; Genetic Diseases, Inborn/physiopathology; Humans; Mental Retardation/classification/*genetics/*physiopathology |
|
| |
Abstract |
About 2-3% of all children are affected by mental retardation, and genetic conditions rank among the leading causes of mental retardation. Alterations in the information encoded by genes that regulate critical steps of brain development can disrupt the normal course of development, and have profound consequences on mental processes. Genetically modified mouse models have helped to elucidate the contribution of specific gene alterations and gene-environment interactions to the phenotype of several forms of mental retardation. Mouse models of several neurodevelopmental pathologies, such as Down and Rett syndromes and X-linked forms of mental retardation, have been developed. Because behavior is the ultimate output of brain, behavioral phenotyping of these models provides functional information that may not be detectable using molecular, cellular or histological evaluations. In particular, the study of ontogeny of behavior is recommended in mouse models of disorders having a developmental onset. Identifying the role of specific genes in neuropathologies provides a framework in which to understand key stages of human brain development, and provides a target for potential therapeutic intervention. |
|
| |
Address |
Section of Behavioural Pathophysiology, Laboratorio di Fisiopatologia di Organo e di Sistema, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy. branchi@iss.it |
|
| |
Corporate Author |
|
Thesis |
|
|
| |
Publisher |
|
Place of Publication |
|
Editor |
|
|
| |
Language |
English |
Summary Language |
|
Original Title |
|
|
| |
Series Editor |
|
Series Title |
|
Abbreviated Series Title |
|
|
| |
Series Volume |
|
Series Issue |
|
Edition |
|
|
| |
ISSN |
0149-7634 |
ISBN |
|
Medium |
|
|
| |
Area |
|
Expedition |
|
Conference |
|
|
| |
Notes |
PMID:12732230 |
Approved |
no |
|
| |
Call Number |
Equine Behaviour @ team @ |
Serial |
2805 |
|
| Permanent link to this record |
