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Author de Waal, F.B.; Uno, H.; Luttrell, L.M.; Meisner, L.F.; Jeannotte, L.A. openurl 
  Title Behavioral retardation in a macaque with autosomal trisomy and aging mother Type Journal Article
  Year 1996 Publication American journal of mental retardation : AJMR Abbreviated Journal Am J Ment Retard  
  Volume 100 Issue 4 Pages 378-390  
  Keywords Animals; *Behavior, Animal; Brain/physiopathology; Female; Hydrocephalus/complications; Longitudinal Studies; Macaca mulatta/*genetics; Magnetic Resonance Imaging; Male; *Maternal Age; Psychomotor Disorders/*etiology; Social Behavior; Trisomy/*genetics; X Chromosome  
  Abstract The social development of a female rhesus monkey (Macaca mulatta) was followed from the day of birth until her death, at age 32 months. The subject, born to an older mother, had an extra autosome (karyotype: 43, XX, +18), an affliction that came about spontaneously. MRI scans revealed that she was also hydrocephalic. Compared to 23 female monkeys growing up under identical conditions, the subject showed serious motor deficiencies, a dramatic delay in the development of social behavior, poorly established dominance relationships, and greater than usual dependency on mother and kin. The subject was well-integrated into the social group, however.  
  Address (down) University of Wisconsin-Madison, USA  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0895-8017 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:8718992 Approved no  
  Call Number refbase @ user @ Serial 205  
Permanent link to this record
 

 
Author Nettle, D. doi  openurl
  Title The evolution of personality variation in humans and other animals Type Journal Article
  Year 2006 Publication The American Psychologist Abbreviated Journal Am Psychol  
  Volume 61 Issue 6 Pages 622-631  
  Keywords Animals; Birds; *Evolution; Female; Fishes; Humans; Insects; Male; Personality/*genetics/*physiology  
  Abstract A comprehensive evolutionary framework for understanding the maintenance of heritable behavioral variation in humans is yet to be developed. Some evolutionary psychologists have argued that heritable variation will not be found in important, fitness-relevant characteristics because of the winnowing effect of natural selection. This article propounds the opposite view. Heritable variation is ubiquitous in all species, and there are a number of frameworks for understanding its persistence. The author argues that each of the Big Five dimensions of human personality can be seen as the result of a trade-off between different fitness costs and benefits. As there is no unconditionally optimal value of these trade-offs, it is to be expected that genetic diversity will be retained in the population.  
  Address (down) University of Newcastle, Newcastle, United Kingdom. daniel.nettle@ncl.ac.uk  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0003-066X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16953749 Approved no  
  Call Number Equine Behaviour @ team @ Serial 4105  
Permanent link to this record
 

 
Author Branchi, I.; Bichler, Z.; Berger-Sweeney, J.; Ricceri, L. openurl 
  Title Animal models of mental retardation: from gene to cognitive function Type Journal Article
  Year 2003 Publication Neuroscience and Biobehavioral Reviews Abbreviated Journal Neurosci Biobehav Rev  
  Volume 27 Issue 1-2 Pages 141-153  
  Keywords Animals; Animals, Genetically Modified/growth & development; Behavior/physiology; Behavior, Animal; Brain/*growth & development; Cognition/*physiology; *Disease Models, Animal; Environment; Genes; Genetic Diseases, Inborn/physiopathology; Humans; Mental Retardation/classification/*genetics/*physiopathology  
  Abstract About 2-3% of all children are affected by mental retardation, and genetic conditions rank among the leading causes of mental retardation. Alterations in the information encoded by genes that regulate critical steps of brain development can disrupt the normal course of development, and have profound consequences on mental processes. Genetically modified mouse models have helped to elucidate the contribution of specific gene alterations and gene-environment interactions to the phenotype of several forms of mental retardation. Mouse models of several neurodevelopmental pathologies, such as Down and Rett syndromes and X-linked forms of mental retardation, have been developed. Because behavior is the ultimate output of brain, behavioral phenotyping of these models provides functional information that may not be detectable using molecular, cellular or histological evaluations. In particular, the study of ontogeny of behavior is recommended in mouse models of disorders having a developmental onset. Identifying the role of specific genes in neuropathologies provides a framework in which to understand key stages of human brain development, and provides a target for potential therapeutic intervention.  
  Address (down) Section of Behavioural Pathophysiology, Laboratorio di Fisiopatologia di Organo e di Sistema, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161 Roma, Italy. branchi@iss.it  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0149-7634 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12732230 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2805  
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Author Drent, P.J.; van Oers, K.; van Noordwijk, A.J. doi  openurl
  Title Realized heritability of personalities in the great tit (Parus major) Type Journal Article
  Year 2003 Publication Proceedings. Biological sciences / The Royal Society Abbreviated Journal Proc Biol Sci  
  Volume 270 Issue 1510 Pages 45-51  
  Keywords Aggression; Animals; Animals, Domestic; Animals, Wild; *Behavior, Animal; Breeding; Exploratory Behavior; Female; *Heredity; Male; Selection (Genetics); Songbirds/*genetics/*physiology; Variation (Genetics)  
  Abstract Behaviour under conditions of mild stress shows consistent patterns in all vertebrates: exploratory behaviour, boldness, aggressiveness covary in the same way. The existence of highly consistent individual variation in these behavioural strategies, also referred to as personalities or coping styles, allows us to measure the behaviour under standardized conditions on birds bred in captivity, link the standardized measurements to the behaviour under natural conditions and measure natural selection in the field. We have bred the great tit (Parus major), a classical model species for the study of behaviour under natural conditions, in captivity. Here, we report a realized heritability of 54 +/- 5% for early exploratory behaviour, based on four generations of bi-directional artificial selection. In addition to this, we measured hand-reared juveniles and their wild-caught parents in the laboratory. The heritability found in the mid-offspring-mid-parent regression was significantly different from zero. We have thus established the presence of considerable amounts of genetic variation for personality types in a wild bird.  
  Address (down) Netherlands Institute of Ecology, PO Box 40, 6666 ZG Heteren, The Netherlands. drent@cto.nioo.knaw.nl  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0962-8452 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:12590770 Approved no  
  Call Number refbase @ user @ Serial 591  
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Author de Waal, F.B. openurl 
  Title The end of nature versus nurture Type Journal Article
  Year 1999 Publication Scientific American Abbreviated Journal Sci Am  
  Volume 281 Issue 6 Pages 94-99  
  Keywords Animals; *Behavior; Behavior, Animal; Ecology; *Environment; Ethology; Evolution; Female; *Genetics; Humans; Instinct; Learning; Male; Sex Characteristics; Twin Studies  
  Abstract  
  Address (down) Living Links Center, Yerkes Regional Primate Research Center, Atlanta, USA  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0036-8733 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:10614071 Approved no  
  Call Number refbase @ user @ Serial 192  
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Author Momozawa, Y.; Takeuchi, Y.; Tozaki, T.; Kikusui, T.; Hasegawa, T.; Raudsepp, T.; Chowdhary, B.P.; Kusunose, R.; Mori, Y. doi  openurl
  Title SNP detection and radiation hybrid mapping in horses of nine candidate genes for temperament Type Journal Article
  Year 2007 Publication Animal Genetics Abbreviated Journal Anim Genet  
  Volume 38 Issue 1 Pages 81-83  
  Keywords Animals; *Behavior, Animal; Breeding; Horses/*genetics/physiology; *Polymorphism, Single Nucleotide; Radiation Hybrid Mapping; *Temperament  
  Abstract  
  Address (down) Laboratory of Veterinary Ethology, The University of Tokyo, Tokyo 113-8657, Japan  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0268-9146 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:17257195 Approved no  
  Call Number Serial 1834  
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Author Ishida, N.; Hirano, T.; Mukoyama, H. openurl 
  Title Detection of aberrant alleles in the D-loop region of equine mitochondrial DNA by single-strand conformation polymorphism (SSCP) analysis Type Journal Article
  Year 1994 Publication Animal Genetics Abbreviated Journal Anim Genet  
  Volume 25 Issue 4 Pages 287  
  Keywords *Alleles; Animals; Base Sequence; *DNA, Mitochondrial; DNA, Single-Stranded/genetics; Female; Gene Frequency; Genomic Imprinting; Horses/*genetics; Male; Molecular Sequence Data; Pedigree; *Polymorphism, Genetic  
  Abstract  
  Address (down) Laboratory of Molecular and Cellular Biology, Japan Racing Association, Tokyo  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0268-9146 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:7985852 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2213  
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Author Ishida, N.; Oyunsuren, T.; Mashima, S.; Mukoyama, H.; Saitou, N. url  openurl
  Title Mitochondrial DNA sequences of various species of the genus Equus with special reference to the phylogenetic relationship between Przewalskii's wild horse and domestic horse Type Journal Article
  Year 1995 Publication Journal of Molecular Evolution Abbreviated Journal J Mol Evol  
  Volume 41 Issue 2 Pages 180-188  
  Keywords Animals; Base Sequence; Chromosomes; Conserved Sequence/genetics; DNA, Mitochondrial/*genetics; Evolution; Genetic Variation/*genetics; Horses/*genetics; Molecular Sequence Data; *Phylogeny; RNA, Transfer, Pro/genetics; Sequence Alignment; Sequence Analysis, DNA  
  Abstract The noncoding region between tRNAPro and the large conserved sequence block is the most variable region in the mammalian mitochondrial DNA D-loop region. This variable region (ca. 270 bp) of four species of Equus, including Mongolian and Japanese native domestic horses as well as Przewalskii's (or Mongolian) wild horse, were sequenced. These data were compared with our recently published Thoroughbred horse mitochondrial DNA sequences. The evolutionary rate of this region among the four species of Equus was estimated to be 2-4 x 10(-8) per site per year. Phylogenetic trees of Equus species demonstrate that Przewalskii's wild horse is within the genetic variation among the domestic horse. This suggests that the chromosome number change (probably increase) of the Przewalskii's wild horse occurred rather recently.  
  Address (down) Laboratory of Molecular and Cellular Biology, Japan Racing Association, Tokyo  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0022-2844 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:7666447 Approved no  
  Call Number Equine Behaviour @ team @ Serial 5042  
Permanent link to this record
 

 
Author Stock, K.F.; Distl, O. openurl 
  Title Evaluation of expected response to selection for orthopedic health and performance traits in Hanoverian Warmblood horses Type Journal Article
  Year 2005 Publication American Journal of Veterinary Research Abbreviated Journal Am J Vet Res  
  Volume 66 Issue 8 Pages 1371-1379  
  Keywords Animals; Bone Diseases/genetics/*veterinary; *Breeding; Genetic Predisposition to Disease; Horse Diseases/*genetics; Horses/*genetics; Joint Diseases/genetics/*veterinary; Selection (Genetics)  
  Abstract OBJECTIVE: To determine whether selection schemes accounting for orthopedic health traits were compatible with breeding progress in performance parameters in Hanoverian Warmblood horses. ANIMALS: 5,928 horses. PROCEDURE: Relative breeding values (RBVs) were predicted for osseous fragments in fetlock (metacarpo- and metatarsophalangeal) and tarsal joints, deforming arthropathy in tarsal joints, and pathologic changes in distal sesamoid bones. Selection schemes were developed on the basis of total indices for radiographic findings (TIR), dressage (TID), and jumping (TIJ). Response to selection was traced over 2 generations of horses for dressage and jumping ability and all-purpose breeding. Development of mean RBVs and mean total indices in sires and prevalences of orthopedic health traits in their offspring were used to assess response to selection. RESULTS: Giving equal weight toTIR andTID, TIJ, or a combined index of 60% TID and 40% TIJ, 43% to 53% of paternal grandsires and 70% to 82% of descending sires passed selection. In each case, RBVs and total indices increased by as much as 9% in selected sires, when compared with all sires, and prevalences of orthopedic health traits in offspring of selected sires decreased relatively by as much as 16%. When selection was exclusively based on TID, TIJ, or TID and TIJ, percentages of selected sires were 44% to 66% in the first and 73% to 84% in the second generation and TID and TIJ increased by 9% to 10% and 19% to 23%, respectively. CONCLUSIONS AND CLINICAL RELEVANCE: Compared with exclusively performance-based selection, percentages of selected sires changed slightly and breeding progress in TID, TIJ, or TID and TIJ was only slightly decreased; however, prevalences of orthopedic health traits decreased in offspring of TIR-selected sires.  
  Address (down) Institute for Animal Breeding and Genetics, University of Veterinary Medicine Hannover (Foundation), Bunteweg 17p, 30559 Hannover, Germany  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0002-9645 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:16173480 Approved no  
  Call Number Equine Behaviour @ team @ Serial 3713  
Permanent link to this record
 

 
Author Ricard, A.; Chanu, I. doi  openurl
  Title Genetic parameters of eventing horse competition in France Type Journal Article
  Year 2001 Publication Genetics, Selection, Evolution. : GSE Abbreviated Journal Genet Sel Evol  
  Volume 33 Issue 2 Pages 175-190  
  Keywords Animals; Behavior, Animal; Female; France; Genotype; Horses/*genetics; Male; Physical Conditioning, Animal; Selection (Genetics); *Sports; Stereotyped Behavior  
  Abstract Genetic parameters of eventing horse competitions were estimated. About 13 000 horses, 30 000 annual results during 17 years and 110 000 starts in eventing competitions during 8 years were recorded. The measures of performance were logarithmic transformations of annual earnings, annual earnings per start, and annual earnings per place, and underlying variables responsible for ranks in each competition. Heritabilities were low (0.11 / 0.17 for annual results, 0.07 for ranks). Genetic correlations between criteria were high (greater than 0.90) except between ranks and earnings per place (0.58) or per start (0.67). Genetic correlations between ages (from 5 to 10 years old) were also high (more than 0.85) and allow selection on early performances. The genetic correlation between the results in different levels of competition (high/international and low/amateur) was near 1. Genetic correlations of eventing with other disciplines, which included partial aptitude needed for eventing, were very low for steeplechase races (0.18) and moderate with sport: jumping (0.45), dressage (0.58). The results suggest that selection on jumping performance will lead to some positive correlated response for eventing performance, but much more response could be obtained if a specific breeding objective and selection criteria were developed for eventing.  
  Address (down) Institut national de la recherche agronomique, Station de genetique quantitative et appliquee, 78352 Jouy-en-Josas Cedex, France. ugenata@dga.inra.fr  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0999-193X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:11333833 Approved no  
  Call Number Equine Behaviour @ team @ Serial 3728  
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