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| Author | Hostikka, S.L.; Eddy, R.L.; Byers, M.G.; Hoyhtya, M.; Shows, T.B.; Tryggvason, K. | ||||
| Title | Identification of a distinct type IV collagen alpha chain with restricted kidney distribution and assignment of its gene to the locus of X chromosome-linked Alport syndrome | Type | Journal Article | ||
| Year | 1990 | Publication | Proceedings of the National Academy of Sciences of the United States of America | Abbreviated Journal | Proc. Natl. Acad. Sci. U.S.A. |
| Volume | 87 | Issue | 4 | Pages | 1606-1610 |
| Keywords | Amino Acid Sequence; Base Sequence; Chromosome Mapping; Cloning, Molecular; Collagen/*genetics; Epitopes/analysis; Female; Fluorescent Antibody Technique; Gene Library; *Genes; Humans; Immunoblotting; Kidney/cytology/*metabolism; Macromolecular Substances; Molecular Sequence Data; Nephritis, Hereditary/*genetics; Oligopeptides/chemical synthesis/immunology; Placenta/metabolism; Pregnancy; Restriction Mapping; Sequence Homology, Nucleic Acid; *X Chromosome | ||||
Abstract  |
We have identified and extensively characterized a type IV collagen alpha chain, referred to as alpha 5(IV). Four overlapping cDNA clones isolated contain an open reading frame for 543 amino acid residues of the carboxyl-terminal end of a collagenous domain, a 229-residue carboxyl-terminal noncollagenous domain, and 1201 base pairs coding for a 3' untranslated region. The collagenous Gly-Xaa-Yaa repeat sequence has five imperfections that coincide with those in the corresponding region of the alpha 1(IV) chain. The noncollagenous domain has 12 conserved cysteine residues and 83% and 63% sequence identity with the noncollagenous domains of the alpha 1(IV) and alpha 2(IV) chains, respectively. The alpha 5(IV) chain has less sequence identity with the putative bovine alpha 3(IV) and alpha 4(IV) chains. Antiserum against an alpha 5(IV) synthetic peptide stained a polypeptide chain of about 185 kDa by immunoblot analysis and immunolocalization of the chain in human kidney was almost completely restricted to the glomerulus. The gene was assigned to the Xq22 locus by somatic cell hybrids and in situ hybridization. This may be identical or close to the locus of the X chromosome-linked Alport syndrome that is believed to be a type IV collagen disease. | ||||
| Address | Biocenter, University of Oulu, Finland | ||||
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| Language | English | Summary Language | Original Title | ||
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| ISSN | 0027-8424 | ISBN | Medium | ||
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| Notes | PMID:1689491 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 5291 | ||
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| Author | Malara, L.; De Pasquale, A.; Ingala, A.; Innella, G. | ||||
| Title | The influence of management on horse behavioural reactivity in therapeutic riding programs. | Type | Conference Article | ||
| Year | 2008 | Publication | IESM 2008 | Abbreviated Journal | |
| Volume | Issue | Pages | |||
| Keywords | Management; Horses; Therapeutic Riding; Behaviour; Reactivity | ||||
| Abstract |
We investigated 8 horses in five therapeutic riding centres situated in San Cataldo (Caltanissetta – I), Nicosia (Catania – II), Pellaro (Reggio Calabria – III), San Gregorio (Catania – IV), Niguarda Hospitals (Milan – V). The managements of the animals were of different typologies: Type 1, Type 2 and Type 3. In type 1 the horses were used for therapeutic riding only. Furthermore intra and interspecific social interactions were not allowed. In type 2 the horses played kinetic activities and made social interactions. In type 3 the horses were free in paddock, as intra and interspecific social interactions were allowed. The centre I, with a management of type 1, housed 1 horse (A1); the centre II, with a management of type 2, housed 1 horse (B2); the centre III, with a management of type 1, housed 1 horse (C1); the centre IV, with a management of type 2, housed 2 horses (D2 and E2); the centre V, with a management of type 3, housed 3 horses (F3, G3 and H3). Breeds of horses were: Anglo-Arab (n°1), Avelignese (n°3), Italian Selle (n°3), draught-horse crossbreed (n°1). They were 2 geldings and 6 females. Their ages ranged from 12 to 23 years. We observed a total of 64 patients affected by different pathologies: autism, motory handicap, blindness and deafness, children“s cerebral paralysis, relational problems, mental deficiency, Down”s syndrome. The horses“ behaviour was observed at rest and during therapeutic activities with these patients. The Heart Rate (HR) was used as physiological parameter for an ethological evaluation, measured by a telemetric heart rate monitor (Polar Horse Trainer). Horses were analysed with a reactivity test for emotional homeostasis evaluation, too. Heart rate values were studied with non parametrical statistical analysis methods. Distinct management typologies provided statistically different basal mean values of heart rate (intergroup and intragroup): Type 1 vs Type 2 (P~0.05) and Type 1 vs Type 3 (P<0.05). The comparison of heart rate during therapeutic activities of diverse management showed the following results: A1 vs B2 (P<0.05), B2 vs C1 (P<0.05), Type 1 vs Type 2 (P<0.01). Different managements, both in the same or different typologies, gave significantly diverse results (A1 vs E2: P~0.05; C1 vs E2: P~0.05; B2 vs E2: P~0.05). This study shows that the statistic differences obtained by therapies with autistic patients derive from management conditions of Type 1. In reactivity test there aren”t any significant differences among the three management typologies. However, we recorded strong variation between medium and maximum values of heart rate, especially in Type 1 and Type 2 of management. These high variations of heart rate indicated fear reaction of the horse to new stimuli. This reaction could lead to dangerous accidents for patients during therapeutic activities. Horses used in therapeutic riding programs must be evaluated before this employment. Horse's behaviour can be assessed by an ethological observation and a reactivity test. Furthermore, the horses must be guaranteed welfare conditions and must live in an environment enriched with sensorial stimuli and respectful of their physiological and ethological needs. |
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| Address | Dept. of Experimental Sciences and Applied Biotechnologies, Unit of Applied Physiology and Comparative Ethology , Faculty of Veterinary Medicine – University of Messina, Italy. | ||||
| Corporate Author | Innella, G. | Thesis | |||
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| ISSN | ISBN | Medium | |||
| Area | Expedition | Conference | IESM 2008 | ||
| Notes | Poster IESM 2008 | Approved | yes | ||
| Call Number | Equine Behaviour @ team @ | Serial | 4491 | ||
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| Author | Imura, T.; Tomonaga, M. | ||||
| Title | Perception of depth from shading in infant chimpanzees ( Pan troglodytes) | Type | Journal Article | ||
| Year | 2003 | Publication | Animal Cognition | Abbreviated Journal | Anim. Cogn. |
| Volume | 6 | Issue | 4 | Pages | 253-258 |
| Keywords | Age Factors; Animals; Contrast Sensitivity/*physiology; Depth Perception/*physiology; Discrimination Learning/*physiology; Female; Male; Pan troglodytes/growth & development/*physiology/*psychology; Pattern Recognition, Visual/physiology | ||||
| Abstract |
We investigated the ability to perceive depth from shading, one of the pictorial depth cues, in three chimpanzee infants aged 4-10 months old, using a preferential reaching task commonly used to study pictorial depth perception in human infants. The chimpanzee infants reached significantly more to three-dimensional toys than to pictures thereof and more to the three-dimensional convex than to the concave. Furthermore, two of the three infants reached significantly more to the photographic convex than to the photographic concave. These infants also looked longer at the photographic convex than the concave. Our results suggest that chimpanzees perceive, at least as early as the latter half of the first year of life, pictorial depth defined by shading information. Photographic convexes contain richer information about pictorial depth (e.g., attached shadow, cast shadow, highlighted area, and global difference in brightness) than simple computer-graphic graded patterns. These cues together might facilitate the infants' perception of depth from shading. | ||||
| Address | Graduate School of Humanities, Kwansei Gakuin University, Uegahara, Nishinomiya, Hyogo 662-8501, Japan | ||||
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| Language | English | Summary Language | Original Title | ||
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| ISSN | 1435-9448 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:14610661 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 2550 | ||
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| Author | Linklater, W.L.; Cameron, E.Z.; Stafford, K.J.; Veltman, C.J. | ||||
| Title | Social and spatial structure and range use by Kaimanawa wild horses (Equus caballus: Equidae) | Type | Journal Article | ||
| Year | 2000 | Publication | New Zealand Journal of Ecology | Abbreviated Journal | New Zealand J. Ecol. |
| Volume | 24 | Issue | 2 | Pages | 139-152 |
| Keywords | Bachelor male; Band; Density; Habitat use; Home range; Management proposals; Micro-climate; Vegetation monitoring; habitat use; home range; mammal; social structure; spatial distribution; New Zealand; Equus caballus | ||||
| Abstract |
We measured horse density, social structure, habitat use, home ranges and altitudinal micro-climates in the south-western Kaimanawa ranges east of Waiouru, New Zealand. Horse density in the Auahitotara ecological sector averaged 3.6 horses.km-2 and ranged from 0.9 to 5.2 horses.km-2 within different zones. The population's social structure was like that of other feral horse populations with an even adult sex ratio, year round breeding groups (bands) with stable adult membership consisting of 1 to 11 mares, 1 to 4 stallions, and their predispersal offspring, and bachelor groups with unstable membership. Bands and bachelor males were loyal to undefended home ranges with central core use areas. Band home range sizes varied positively with adult band size. Home ranges overlapped entirely with other home ranges. Horses were more likely to occupy north facing aspects, short tussock vegetation and flush zones and avoid high altitudes, southern aspects, steeper slopes, bare ground and forest remnants. Horses were more likely to be on north facing aspects, steeper slopes, in exotic and red tussock grasslands and flush zones during winter and at lower altitudes and on gentler slopes in spring and summer. Seasonal shifts by bands to river basin and stream valley floors in spring and higher altitudes in autumn and winter are attributed to the beginning of foaling and mating in spring and formation of frost inversion layers in winter. Given horse habitat selectivity and the presence of other ungulate herbivores, results from present exclosures are likely to exaggerate the size of horse impacts on range vegetation. Proposals to manage the population by relocation and confinement are likely to modify current social structure and range use behaviour and may lead to the need for more intensive management in the longer term. | ||||
| Address | Ecology Group, Institute of Natural Resources, Massey University, Private Bag 11-222, Palmerston North, New Zealand | ||||
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| ISSN | 01106465 (Issn) | ISBN | Medium | ||
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| Notes | Cited By (since 1996): 12; Export Date: 21 April 2007; Source: Scopus; Language of Original Document: English; Correspondence Address: Linklater, W.L.; Ecology Group; Institute of Natural Resources; Massey University; Private Bag 11-222 Palmerston North, New Zealand; email: wlinklater@hotmail.com | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 793 | ||
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| Author | Houpt, K.A.; Northrup, N.; Wheatley, T.; Houpt, T.R. | ||||
| Title | Thirst and salt appetite in horses treated with furosemide | Type | Journal Article | ||
| Year | 1991 | Publication | Journal of applied physiology (Bethesda, Md. : 1985) | Abbreviated Journal | J Appl Physiol |
| Volume | 71 | Issue | 6 | Pages | 2380-2386 |
| Keywords | Animals; Appetite/*drug effects; Blood Volume; Diuresis; Drinking/drug effects; Female; Furosemide/*pharmacology; Horses; Natriuresis; Sodium, Dietary/*administration & dosage; Thirst/*drug effects | ||||
| Abstract |
When a preliminary experiment in sodium-replete ponies revealed an increase, but not a significant increase, in salt consumption after furosemide treatment, the experiment was repeated using sodium-deficient horses in which aldosterone levels might be expected to be elevated to test the hypothesis that a background of aldosterone is necessary for salt appetite. Ten Standardbred mares were injected intravenously with furosemide or an equivalent volume of 0.9% sodium chloride as a control to test the effect of furosemide on their salt appetite and blood constituents. Sodium intake and sodium loss in urine, as well as water intake and urine output, were measured and compared to determine accuracy of compensation for natriuresis and diuresis. Plasma protein and packed cell volume showed significant increases in response to furosemide treatment (F = 29.31, P less than 0.001 and F = 11.20, P less than 0.001, respectively). There were no significant changes in plasma sodium concentration or osmolality in response to the treatment (P greater than 0.05). The furosemide-treated horses consumed 126 +/- 14.8 g salt, significantly more than when they were given the control injection (94.5 +/- 9.8 g; t = 2.22, P = 0.05). In response to furosemide, horses lost 962 +/- 79.7 and consumed 2,170 +/- 5 meq sodium; however, compared with control, they lost 955 meq more sodium and ingested only 570 meq more sodium, so they were undercompensating for natriuresis. The furosemide-treated horses drank 9.6 +/- 0.8 kg of water, significantly more than when they received the control injection (6.4 +/- 0.8 kg; t = 6.9, P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS) | ||||
| Address | Department of Physiology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853-6401 | ||||
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| Language | English | Summary Language | Original Title | ||
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| ISSN | 8750-7587 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:1778936 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 38 | ||
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| Author | Lonon, A.M.; Zentall, T.R. | ||||
| Title | Transfer of value from S+ to S- in simultaneous discriminations in humans | Type | Journal Article | ||
| Year | 1999 | Publication | The American journal of psychology | Abbreviated Journal | Am J Psychol |
| Volume | 112 | Issue | 1 | Pages | 21-39 |
| Keywords | Adolescent; Adult; Animals; Color Perception; Columbidae; Conditioning, Classical; *Discrimination Learning; Female; Humans; Male; Middle Aged; *Motivation; Orientation; Pattern Recognition, Visual; Psychomotor Performance; Reaction Time; *Transfer (Psychology) | ||||
| Abstract |
When animals learn a simultaneous discrimination, some of the value of the positive stimulus (S+) appears to transfer to the negative stimulus (S-). The present experiments demonstrate that such value transfer can also be found in humans. In Experiment 1 humans were trained on 2 simple simultaneous discriminations, the first between a highly positive stimulus, A (1,000 points); and a negative stimulus, B (0 points); and the second between a less positive stimulus, C (100 points); and a negative stimulus, D (0 points). On test trials, most participants preferred B over D. In Experiments 2 and 3 the value of the 2 original discriminations was equated in training (A[100]B[0] and C[100]D[0]). In Experiment 2 the values of the positive stimuli were then altered (A[1,000]C[0]); again, most participants preferred B over D. In Experiment 3, however, when the values of B and D were altered (B[1,000]D[0]), participants were indifferent to A and C. Thus, the mechanism that underlies value transfer in humans appears to be related to Pavlovian second-order conditioning. Similar mechanisms may be involved in assimilation processes in social contexts. | ||||
| Address | University of Kentucky, USA | ||||
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| Language | English | Summary Language | Original Title | ||
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| ISSN | 0002-9556 | ISBN | Medium | ||
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| Notes | PMID:10696277 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 249 | ||
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| Author | Watanabe, S.; Huber, L. | ||||
| Title | Animal logics: decisions in the absence of human language | Type | Journal Article | ||
| Year | 2006 | Publication | Animal Cognition | Abbreviated Journal | Anim. Cogn. |
| Volume | 9 | Issue | 4 | Pages | 235-245 |
| Keywords | *Animal Communication; Animals; Behavior, Animal/*physiology; Brain/physiology; Cognition/*physiology; Decision Making/*physiology; Evolution; Humans; *Language; *Logic; Problem Solving/physiology | ||||
| Abstract |
Without Abstract | ||||
| Address | Department of Psychology, Keio University, Mita 2-15-45, Minato-ku, Tokyo 108, Japan. swat@flet.keio.ac.jp | ||||
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| Language | English | Summary Language | Original Title | ||
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| ISSN | 1435-9448 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:16909231 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 2453 | ||
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| Author | Lyn, H.; Savage-Rumbaugh, E.S. | ||||
| Title | Observational word learning in two bonobos (Pan paniscus): ostensive and non-ostensive contexts | Type | Journal Article | ||
| Year | 2000 | Publication | Language & Communication | Abbreviated Journal | |
| Volume | 20 | Issue | 3 | Pages | 255-273 |
| Keywords | Language acquisition; Bonobo; Fast mapping | ||||
| Abstract |
Word learning has been extensively studied in humans. Children seem to be able to map new words onto objects with only one exposure to the referent. This ability has been called “fast mapping”(Carey, 1978 and Carey). Using a modified human paradigm, this paper explores two language-competent bonobos' (Pan paniscus) abilities to map new words to objects in realistic surroundings with few exposures to the referents. This paper also investigates the necessity of the apes maintaining visual contact (ostensive context) with the item to map the novel name onto the novel object. The bonobos tested in this experiment were able to map new words onto objects and could do so without visual contact with the items. | ||||
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| Call Number | Equine Behaviour @ team @ | Serial | 4675 | ||
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| Author | Gehlen, H.; Große, V.; Doher, M. | ||||
| Title | Möglichkeiten und Grenzen des Herdenschutzes für Pferde in Zusammenhang mit der wachsenden Wolfspopulation in Deutschland Literaturrecherche und Befragung von Pferdehaltern zur Gefährdungsbeurteilung [Options and limitations of protecting horse husbandries in times of growing wolf populations in Germany Review of the literature and horse owner questionnaire on risk assessment] | Type | Journal Article | ||
| Year | 2012 | Publication | Tierärztliche Praxis Großtier/Nutztier Ausgabe G | Abbreviated Journal | Tierarztl Prax Ausg G |
| Volume | 49 | Issue | 05 | Pages | 301-309 |
| Keywords | Wolfsrisse – Bedrohung – Weidehaltung – Pferdehaltung – Verletzungen; Wolf kill – threat – pasture management – horse husbandry – injury | ||||
| Abstract |
Zusammenfassung Gegenstand und Ziel Seit 2000 siedelt sich der Wolf in Deutschland wieder an. Mit steigenden Wolfszahlen nehmen die durch Wölfe verursachten Nutztierschäden zu, wobei auch Pferde betroffen sind. Ziel der Studie war es, einen Überblick zu dieser Problematik sowie Lösungsansätze zu geben. Material und Methoden Anhand einer Literaturrecherche wurden Daten zur Wolfspopulation in Deutschland, wolfsbedingten Schäden sowie Möglichkeiten und Grenzen des Herdenschutzes beim Pferd eruiert. Eine Online-Befragung von Pferdehaltern/-besitzern diente dazu, die tatsächliche und/oder gefühlte Bedrohung durch Wölfe und die daraus resultierenden Auswirkungen auf die Pferdehaltung zu ermitteln. Ergebnisse Die Literaturrecherche zeigte ein kontinuierliches Anwachsen der Wolfspopulation in den letzten Jahren und insbesondere seit 2016 einen deutlichen Anstieg wolfsverursachter Nutztierschäden, wobei Pferde selten betroffen waren. Bei der Online-Befragung stammte die Hälfte der 574 ausgewerteten Fragebögen aus Brandenburg und Niedersachsen. Den größten Einfluss auf die Gefährdungsbeurteilung eigener Pferde durch die wachsende Wolfspopulation hatte das Wissen der Pferdehalter über Wolfsangriffe im eigenen Landkreis, wobei insbesondere die Aspekte einer Haltung von Jungpferden und Weidegang für die Pferde eine Rolle spielten. 64 % der Befragten gaben an, ihre Pferdehaltung trotz der zunehmenden Wolfspopulation nicht geändert zu haben. Nur 8 von 576 Pferdehaltern gaben amtlich bestätigte Wolfsübergriffe an und 30 hatten einen vermuteten Wolfsschaden amtlichen Stellen nicht gemeldet. Mehr als die Hälfte der Befragten, die Kontakt zu einem Wolfsberater hatten, bezeichneten die Zusammenarbeit als nicht bis wenig zielführend. Schlussfolgerung und klinische Relevanz Die Zahl amtlich bestätigter Wolfsangriffe auf Pferde ist gering. Durch einen grundsätzlich durchgeführten Gentest bei entsprechendem Verdacht ließen sich diese Zahlen objektivieren. Trotz des Bewusstseins einer zunehmenden Gefährdung von Pferden durch Wölfe unternehmen Pferdehalter überwiegend keine prophylaktischen Schutzmaßnahmen. Die Kommunikation zwischen den für das Wolfsmonitoring zuständigen Behörden und den Pferdehaltern erscheint verbesserungswürdig. Abstract Objective Since 2000 the wolf population is reestablishing itself in Germany. In consequence to increasing numbers, livestock damage caused by wolves is on the rise, with horses likewise being affected. The aim of the study was to provide an overview of this challenge and its possible solutions. Material and methods Based on a literature research, data on the wolf population in Germany, wolf-related damage as well as possibilities and limitations of herd protection for horses were evaluated. An online survey addressed to horse owners/keepers served to determine the actual and/or perceived threat posed by wolves and the resulting effects on horse husbandry. Results The literature search showed a continuous increase of the wolf population in recent years as well as a significant increase of wolf-caused livestock damage in general especially since 2016; although horses were rarely affected. Half of the 574 evaluated questionnaires were from Brandenburg and Lower Saxony. The greatest influence on the individual risk assessment concerning their own horses by the growing wolf population was the horse owners� knowledge of wolf attacks in their own county. Especially the aspects of keeping young horses as well as pasture keeping played a significant role. 64 % of respondents indicated that they had not changed their horse management practices despite the increasing wolf population. Only 8 of 576 horse owners had reported officially confirmed wolf attacks and 30 respondents had not reported a suspected wolf damage to official agencies. More than half of the respondents who had contact with a wolf advisor described the cooperation as either not or only slightly purposeful. Conclusion and clinical relevance The number of officially confirmed wolf attacks on horses is low. These numbers could be objectified by a routinely performed genetic test in case of corresponding suspicion. Despite the awareness of an increasing danger of horses by wolves, horse owners mostly do not undertake prophylactic protection measures. The communication between responsible authorities for wolf monitoring and horse owners seems to be in need of improvement. |
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| Notes | Approved | no | |||
| Call Number | Equine Behaviour @ team @ | Serial | 6673 | ||
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