toggle visibility Search & Display Options

Select All    Deselect All
 |   | 
Details
   print
  Records Links
Author Maury, M.; Murphy, K.; Kumar, S.; Mauerer, A.; Lee, G. url  doi
openurl 
  Title Spray-drying of proteins: effects of sorbitol and trehalose on aggregation and FT-IR amide I spectrum of an immunoglobulin G Type Journal Article
  Year 2005 Publication European Journal of Pharmaceutics and Biopharmaceutics Abbreviated Journal (down) Eur. J. Pharm. Biopharm.  
  Volume 59 Issue 2 Pages 251-261  
  Keywords Immunoglobulin; Spray-drying; Stabilization; Sorbitol; Trehalose; Water replacement  
  Abstract An immunoglobulin G (IgG) was spray-dried on a Büchi 190 laboratory spray-dryer at inlet and outlet air temperatures of 130 and 190°C, respectively. The IgG solution contains initially 115mg/ml IgG plus 50mg/ml sorbitol. After dialysis, at least 80% of low molecular weight component was removed. After spray-drying the dialyzed IgG and immediate redissolution of the powder, an increase in aggregates from 1 to 17% occurred. A major shift towards increase β-sheet structure was detected in the spray-dried solid, which, however, reverted to native structure on redissolution of the powder. A correlation between aggregation determined by size exclusion chromatography and alterations in secondary structure determined by Fourier transformation infra-red spectroscopy could not therefore be established. On spray-drying a non-dialyzed, sorbitol-containing IgG only some 0.7% aggregates were formed. The sorbitol is therefore evidently able to stabilize partially the IgG during the process of spray-drying. Addition of trehalose to the liquid feed produced quantitatively the same stabilizing action on the IgG during spray-drying as did the sorbitol. This finding again points towards a water replacement stabilization mechanism. The IgG spray-dried powder prepared from the dialyzed liquid feed showed continued substantial aggregation on dry storage at 25°C. This was substantially less in the non-dialyzed, sorbitol-containing spray-dried powder. Addition of trehalose to both dialyzed and non-dialyzed system produced substantial improvement in storage stability and reduction in aggregate formation in storage. The quantitative stabilizing effect of the trehalose was only slightly higher than that of the sorbitol. Taken together, these results indicate that both the sorbitol and trehalose stabilize the IgG primarily by a water replacement mechanism rather than by glassy immobilization. The relevance of this work is its questioning of the importance of the usually considered dominance of glassy stabilization of protein in dried systems of high glass transition temperature, such as trehalose. The low glass transition temperature sorbitol produces almost equal process and storage stability in this case.  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0939-6411 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number Equine Behaviour @ team @ Serial 6515  
Permanent link to this record
 

 
Author Meriggi, A.; Dagradi, V.; Dondina, O.; Perversi, M.; Milanesi, P.; Lombardini, M.; Raviglione, S.; Repossi, A. url  doi
openurl 
  Title Short-term responses of wolf feeding habits to changes of wild and domestic ungulate abundance in Northern Italy Type Journal Article
  Year 2014 Publication Ethology Ecology & Evolution Abbreviated Journal (down) Ethology Ecology & Evolution  
  Volume 27 Issue 4 Pages 389-411  
  Keywords  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Taylor & Francis Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0394-9370 ISBN Medium  
  Area Expedition Conference  
  Notes doi: 10.1080/03949370.2014.986768 Approved no  
  Call Number Equine Behaviour @ team @ Serial 6688  
Permanent link to this record
 

 
Author Rutberg, A.T. url  doi
openurl 
  Title Horse Fly Harassment and the Social Behavior of Feral Ponies Type Journal Article
  Year 1987 Publication Ethology Abbreviated Journal (down) Ethology  
  Volume 75 Issue 2 Pages 145-154  
  Keywords  
  Abstract Abstract Horse flies (Tabanidae) on and around feral ponies in harem groups were counted at Assateague Island National Seashore, Maryland, U.S.A., between June and August 1985. Harem stallions attracted the most flies; adult mares showed intermediate fly numbers, while few flies landed on foals under any circumstances. The use of thermal and chemical cues by flies selecting a host may have helped create this disparity. When flies were abundant, ponies reduced spacing within the group. Ponies in larger groups suffered from fewer flies than ponies in smaller groups. There was, however, no evidence that ponies merged into larger groups in response to fly harassment, suggesting that biting flies play little role in structuring pony social organization.  
  Address  
  Corporate Author Thesis  
  Publisher Wiley/Blackwell (10.1111) Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0179-1613 ISBN Medium  
  Area Expedition Conference  
  Notes doi: 10.1111/j.1439-0310.1987.tb00648.x Approved no  
  Call Number Equine Behaviour @ team @ Serial 6417  
Permanent link to this record
 

 
Author Krange, O.; Skogen, K. url  doi
openurl 
  Title When the lads go hunting: The 'Hammertown mechanism' and the conflict over wolves in Norway Type Journal Article
  Year 2011 Publication Ethnography Abbreviated Journal (down) Ethnography  
  Volume 12 Issue 4 Pages 466-489  
  Keywords  
  Abstract Rural communities are changing. Depopulation and unemployment is accompanied by the advance of new perspectives on nature, where protection trumps resource extraction. These developments are perceived as threatening by rural working-class people with close ties to traditional land use ? a situation they often meet with cultural resistance. Cultural resistance is not necessarily launched against institutionalized power, nor does it necessarily imply a desire for fundamental social change. It should rather be seen as a struggle for autonomy. However, autonomy does not entail influence outside the cultural realm. Struggles to uphold traditional rural lifestyles ? for example by denouncing the current nature conservation regime ? could be understood in much the same conceptual framework as Willis employed in ?Learning to labour?. Based on an ethnographic study of the conflicts over wolf protection, we demonstrate that ?the Hammertown mechanism? is of a more general nature than often implied in the discussion of Willis? work.  
  Address  
  Corporate Author Thesis  
  Publisher SAGE Publications Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1466-1381 ISBN Medium  
  Area Expedition Conference  
  Notes doi: 10.1177/1466138110397227 Approved no  
  Call Number Equine Behaviour @ team @ Serial 6425  
Permanent link to this record
 

 
Author Drevemo, S.; Fredricson, I.; Hjertén, G.; McMIKEN, D. url  doi
openurl 
  Title Early development of gait asymmetries in trotting Standardbred colts Type Journal Article
  Year 1987 Publication Equine Veterinary Journal Abbreviated Journal (down) Equine. Vet. J.  
  Volume 19 Issue 3 Pages 189-191  
  Keywords  
  Abstract Summary Ten trotting Standardbred colts were recorded by high-speed cinematography at the ages of eight, 12 and 18 months. The horses were trotting on a treadmill operating at 4.0 m/secs. Five horses were subjected to a programme of intensified training from eight months of age, whereas the others were not trained and acted as controls. The films were analysed on a semi-automatic film-reading equipment and a number of variables used to demonstrate the gait symmetry were calculated and scaled by computer. Certain differences between left and right diagonal and contralateral pair of limbs, respectively, were noted, suggesting that laterality in horses may be inherited. The most pronounced systematic differences were found in 18-month old horses in the trained group. The results show the importance of careful gait examination and comprehensive coordination training at an early age.  
  Address  
  Corporate Author Thesis  
  Publisher American Medical Association (AMA) Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes https://doi.org/10.1111/j.2042-3306.1987.tb01373.x Approved no  
  Call Number Equine Behaviour @ team @ Serial 6702  
Permanent link to this record
 

 
Author Morgan, K.; Funkquist, P.; Nyman, G. url  doi
openurl 
  Title The effect of coat clipping on thermoregulation during intense exercise in trotters Type Journal Article
  Year 2002 Publication Equine Veterinary Journal Abbreviated Journal (down) Equine Veterinary Journal  
  Volume 34 Issue S34 Pages 564-567  
  Keywords horse; thermoregulation; heat loss; recovery; blood temperature; oxygen uptake  
  Abstract Summary The aim of this study was to study the physiological, especially thermoregulatory, responses during intense exercise in the clipped horse compared to the horse with winter coat. Six Standardbred trotters were studied before and after clipping. They performed an inclined incremental high intensity treadmill exercise test and were monitored during recovery. The clipped horse differed significantly (ANOVA) during exercise as compare to coated: less increase in central venous blood temperature, higher skin surface temperature, greater difference skin to ambient temperature and higher rate of nonevaporative heat loss. The clipped horse had significantly lower total cutaneous evaporative heat loss from walk to end of peak exercise and a shorter time for recovery for the respiratory rate using a paired t test. The clipped horse showed a tendency (P = 0.059) to decreased oxygen uptake during the stepwise increase in workload. We concluded that the clipped horse experienced less strain on the thermoregulatory system due to an enhanced heat loss. Some clipped horses in the study showed a more efficient power output; future studies with emphasis on respiration and oxygen demand are needed to explain this.  
  Address  
  Corporate Author Thesis  
  Publisher American Medical Association (AMA) Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes doi: 10.1111/j.2042-3306.2002.tb05484.x Approved no  
  Call Number Equine Behaviour @ team @ Serial 6614  
Permanent link to this record
 

 
Author Goodwin, D. url  doi
openurl 
  Title The importance of ethology in understanding the behaviour of the horse Type Journal Article
  Year 1999 Publication Equine Veterinary Journal Abbreviated Journal (down) Equine Veterinary Journal  
  Volume 31 Issue S28 Pages 15-19  
  Keywords horse; behaviour; domestication; interspecific communication  
  Abstract Summary Domestication has provided the horse with food, shelter, veterinary care and protection, allowing individuals an increased chance of survival. However, the restriction of movement, limited breeding opportunities and a requirement to expend energy, for the benefit of another species, conflict with the evolutionary processes which shaped the behaviour of its predecessors. The behaviour of the horse is defined by its niche as a social prey species but many of the traits which ensured the survival of its ancestors are difficult to accommodate in the domestic environment. There has been a long association between horses and man and many features of equine behaviour suggest a predisposition to interspecific cooperation. However, the importance of dominance in human understanding of social systems has tended to overemphasise its importance in the human-horse relationship. The evolving horse-human relationship from predation to companionship, has resulted in serial conflicts of interest for equine and human participants. Only by understanding the nature and origin of these conflicts can ethologists encourage equine management practices which minimise deleterious effects on the behaviour of the horse.  
  Address  
  Corporate Author Thesis  
  Publisher American Medical Association (AMA) Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes Approved no  
  Call Number Equine Behaviour @ team @ Serial 6714  
Permanent link to this record
 

 
Author Bonin, S.J.; Clayton, H.M.; Lanovaz, J.L.; Johnston, T. url  doi
openurl 
  Title Comparison of mandibular motion in horses chewing hay and pellets Type Journal Article
  Year 2007 Publication Equine Veterinary Journal Abbreviated Journal (down) Equine Vet. J.  
  Volume 39 Issue 3 Pages 258-262  
  Keywords horse; temporomandibular joint; mastication; kinematics  
  Abstract Summary Reasons for performing study: Previous studies have suggested that temporomandibular joint (TMJ) kinematics depend on the type of food being masticated, but accurate measurements of TMJ motion in horses chewing different feeds have not been published. Hypothesis: The temporomandibular joint has a larger range of motion when horses chew hay compared to pellets. Methods: An optical motion capture system was used to track skin markers on the skull and mandible of 7 horses as they chewed hay and pellets. A virtual marker was created on the midline between the mandibles at the level of the 4th premolar teeth to represent the overall motion of the mandible relative to the skull during the chewing cycle. Results: Frequency of the chewing cycles was lower for hay than for pellets. Excursions of the virtual mandibular marker were significantly larger in all 3 directions when chewing hay compared to pellets. The mean velocity of the virtual mandibular marker during the chewing cycle was the same when chewing the 2 feeds. Conclusions: The range of mediolateral displacement of the mandible was sufficient to give full occlusal contact of the upper and lower dental arcades when chewing hay but not when chewing pellets. Potential relevance: These findings support the suggestion that horses receiving a diet high in concentrate feeds may require more frequent dental prophylactic examinations and treatments to avoid the development of dental irregularities associated with smaller mandibular excursions during chewing.  
  Address  
  Corporate Author Thesis  
  Publisher American Medical Association (AMA) Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes doi: 10.2746/042516407X157792 Approved no  
  Call Number Equine Behaviour @ team @ Serial 6513  
Permanent link to this record
 

 
Author Dyson, S. url  doi
openurl 
  Title The Ridden Horse Pain Ethogram Type Journal Article
  Year 2022 Publication Equine Veterinary Education Abbreviated Journal (down) Equine Vet Educ  
  Volume 34 Issue 7 Pages 372-380  
  Keywords horse; lameness; canter; behaviour; saddle-fit; rider skill  
  Abstract Summary The Ridden Horse Pain Ethogram (RHpE) comprises 24 behaviours, the majority of which are at least 10 times more likely to be seen in lame horses compared with non-lame horses. The observation of >=8/24 behaviours is likely to reflect the presence of musculoskeletal pain, although some lame horses score <8/24 behaviours. A marked reduction in RHpE scores after resolution of lameness using diagnostic anaesthesia proves a causal relationship between pain and RHpE scores. Horses should be assessed for approximately 10?min in walk, trot (including 10?m diameter circles), canter and transitions. The validity of the RHpE has been verified for use in horses which perform dressage-type movements, and which have been trained to work with the front of the head in a vertical position. It has not, as yet, been used in horses while jumping, racehorses, western performance or endurance horses. The RHpE provides a valuable tool for riders, trainers, veterinarians and other equine professionals to recognise the presence of musculoskeletal pain, even if overt lameness cannot be recognised. Riders with a higher skill-level may improve gait quality, but cannot obscure behavioural signs of pain, although specific behaviours may change. Tight saddle tree points, the rider sitting on the caudal third of the saddle and rider weight may influence RHpE scores. Accurate application of the RHpE requires training and practice. The RHpE is a powerful tool for the assessment of ridden horses and the identification of likely musculoskeletal pain. Such pain merits further investigation and treatment, to improve equine welfare and performance. The RHpE provides an additional means of evaluating the response to diagnostic anaesthesia. It provides a mechanism for client education and a diplomatic way of communicating with clients about equine discomfort related to saddle-fit, rider size, their position in the saddle and ability to ride in balance.  
  Address  
  Corporate Author Thesis  
  Publisher American Medical Association (AMA) Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0957-7734 ISBN Medium  
  Area Expedition Conference  
  Notes https://doi.org/10.1111/eve.13468 Approved no  
  Call Number Equine Behaviour @ team @ Serial 6693  
Permanent link to this record
 

 
Author Gleerup, K.B.; Lindegaard, C. url  doi
openurl 
  Title Recognition and quantification of pain in horses: A tutorial review Type Journal Article
  Year 2016 Publication Equine Veterinary Education Abbreviated Journal (down) Equine Vet Educ  
  Volume 28 Issue 1 Pages 47-57  
  Keywords horse; pain evaluation; pain scale; pain behaviour; pain face  
  Abstract Summary Pain management is dependent on the quality of the pain evaluation. Ideally, pain evaluation is objective, pain-specific and easily incorporated into a busy equine clinic. This paper reviews the existing knowledge base regarding the identification and quantification of pain in horses. Behavioural indicators of pain in horses in the context of normal equine behaviour, as well as various physiological parameters potentially useful for pain evaluation, are discussed. Areas where knowledge is sparse are identified and a new equine pain scale based on results from all reviewed papers is proposed. Finally, the most important considerations in relation to the implementation of a pain scale in a hospital setting are discussed.  
  Address  
  Corporate Author Thesis  
  Publisher American Medical Association (AMA) Place of Publication Editor  
  Language Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0957-7734 ISBN Medium  
  Area Expedition Conference  
  Notes https://doi.org/10.1111/eve.12383 Approved no  
  Call Number Equine Behaviour @ team @ Serial 6705  
Permanent link to this record
Select All    Deselect All
 |   | 
Details
   print