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Bouchard, T.J.J.; Loehlin, J.C. |
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Title |
Genes, evolution, and personality |
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Journal Article |
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Year |
2001 |
Publication |
Behavior Genetics |
Abbreviated Journal  |
Behav Genet |
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Volume |
31 |
Issue |
3 |
Pages |
243-273 |
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Keywords |
Animals; *Evolution; Genetics, Behavioral; Humans; Individuality; Personality/*genetics; Twin Studies |
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Abstract |
There is abundant evidence, some of it reviewed in this paper, that personality traits are substantially influenced by the genes. Much remains to be understood about how and why this is the case. We argue that placing the behavior genetics of personality in the context of epidemiology, evolutionary psychology, and neighboring psychological domains such as interests and attitudes should help lead to new insights. We suggest that important methodological advances, such as measuring traits from multiple viewpoints, using large samples, and analyzing data by modern multivariate techniques, have already led to major changes in our view of such perennial puzzles as the role of “unshared environment” in personality. In the long run, but not yet, approaches via molecular genetics and brain physiology may also make decisive contributions to understanding the heritability of personality traits. We conclude that the behavior genetics of personality is alive and flourishing but that there remains ample scope for new growth and that much social science research is seriously compromised if it does not incorporate genetic variation in its explanatory models. |
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Department of Psychology. University of Minnesota, Minneapolis 55455, USA. bouch001@tc.umn.edu |
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0001-8244 |
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PMID:11699599 |
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Equine Behaviour @ team @ |
Serial |
4142 |
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Author |
Weiss, A.; King, J.E.; Figueredo, A.J. |
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Title |
The heritability of personality factors in chimpanzees (Pan troglodytes) |
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Journal Article |
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Year |
2000 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
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Volume |
30 |
Issue |
3 |
Pages |
213-221 |
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Animals; Female; Humans; Male; Models, Genetic; Pan troglodytes/*genetics; Personality/*genetics; Social Environment |
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Abstract |
Human personality and behavior genetic studies have resulted in a growing consensus that five heritable factors account for most variance in human personality. Prior research showed that chimpanzee personality is composed of a dominance-related factor and five human-like factors--Surgency, Dependability, Emotional Stability, Agreeableness, and Openness. Genetic, shared zoo, and nonshared environmental variance components of the six factors were estimated by regressing squared phenotypic differences of all possible pairs of chimpanzees onto 1 – Rij, where Rij equals the degree of relationship and a variable indicating whether the pair was housed in the same zoo. Dominance showed significant narrow-sense heritability. Shared zoo effects accounted for only a negligible proportion of the variance for all factors. |
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Department of Psychology, University of Arizona, Tucson 85721, USA. aweiss@u.arizona.edu |
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0001-8244 |
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PMID:11105395 |
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Equine Behaviour @ team @ |
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4143 |
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Author |
Boice, R. |
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Title |
Behavioral comparability of wild and domesticated rats |
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Journal Article |
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Year |
1981 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
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Volume |
11 |
Issue |
5 |
Pages |
545-553 |
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Keywords |
Animals; *Behavior, Animal; Female; Genetics, Behavioral; Intelligence; Learning; Male; Rats/*genetics |
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The oft-repeated concern for the lack of behavioral comparability of domestic rats with wild forms of Rattus norvegicus is unfounded. Laboratory rats appear to show the potential for all wild-type behaviors, including the most dramatic social postures. Moreover, domestics are capable of assuming a feral existence without difficulty, one where they readily behave in a fashion indistinguishable from wild rats. The one behavioral difference that is clearly established concerns performance in laboratory learning paradigms. The superiority of domestics in these laboratory tasks speaks more to quieting the concerns of degeneracy theorists than to problems of using domestic Norway rats as subjects representative of their species. |
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0001-8244 |
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PMID:7325955 |
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Equine Behaviour @ team @ |
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4144 |
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Author |
McClearn, G.E. |
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Title |
Behavioral genetics |
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Journal Article |
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Year |
1971 |
Publication |
Behavioral Science |
Abbreviated Journal |
Behav Sci |
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Volume |
16 |
Issue |
1 |
Pages |
64-81 |
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Keywords |
Amino Acid Metabolism, Inborn Errors; Animals; Aptitude; Behavior, Animal; Chromosome Aberrations; Cognition; Cytogenetics; Female; *Genetics, Behavioral; Genetics, Population; Humans; Intelligence; Mental Retardation; Mice; Models, Biological; Personality; Phenylketonurias; Pregnancy; Research; Schizophrenia; Sex Chromosome Aberrations; Twins |
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0005-7940 |
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PMID:5105941 |
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Equine Behaviour @ team @ |
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4150 |
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Crosby, M.B.; Zhang, J.; Nowling, T.M.; Svenson, J.L.; Nicol, C.J.; Gonzalez, F.J.; Gilkeson, G.S. |
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Title |
Inflammatory modulation of PPAR gamma expression and activity |
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Journal Article |
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Year |
2006 |
Publication |
Clinical immunology |
Abbreviated Journal |
Clin Immunol |
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118 |
Issue |
2-3 |
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276-283 |
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Keywords |
Age Factors; Animals; Cell Line, Transformed; Cells, Cultured; Female; Inflammation Mediators/*physiology; Kidney/metabolism; Mesangial Cells/metabolism; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Mice, Knockout; Nitric Oxide/biosynthesis; Nitric Oxide Synthase Type II/biosynthesis/genetics; PPAR gamma/*biosynthesis/*genetics/metabolism; Up-Regulation/immunology |
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Abstract |
Nitric oxide (NO) production increases with age in the lupus-prone MRL/lpr mouse, paralleling disease activity. One mechanism for excess NO production in MRL/lpr mice may be a defect in down-regulatory mechanisms of the iNOS pathway. A potential modulator of NO is the nuclear hormone receptor peroxisome proliferation activated receptor gamma (PPARgamma). We demonstrate that renal PPARgamma protein expression was altered as disease progressed in MRL/lpr mice, which paralleled increased iNOS protein expression. Additionally, MRL/lpr-derived primary mesangial cells expressed less PPARgamma than BALB/c mesangial cells and produced more NO in response to LPS and IFNgamma. Furthermore, PPARgamma activity was reduced in mesangial cells following exposure to inflammatory mediators. This activity was restored with the addition of a NOS enzyme inhibitor. These results indicate that the activation of inflammatory pathways may lead to reduced activity and expression of PPARgamma, further exacerbating the disease state. |
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Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA |
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1521-6616 |
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PMID:16303334 |
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Call Number |
refbase @ user @ |
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67 |
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Author |
Edwards, D.H.; Spitzer, N. |
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Title |
6. Social dominance and serotonin receptor genes in crayfish |
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Journal Article |
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Year |
2006 |
Publication |
Current Topics in Developmental Biology |
Abbreviated Journal |
Curr Top Dev Biol |
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74 |
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177-199 |
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Animals; Astacoidea/*genetics/physiology; Humans; Receptors, Serotonin/*genetics; Serotonin/physiology; *Social Dominance |
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Abstract |
Gene expression affects social behavior only through changes in the excitabilities of neural circuits that govern the release of the relevant motor programs. In turn, social behavior affects gene expression only through patterns of sensory stimulation that produce significant activation of relevant portions of the nervous system. In crayfish, social interactions between pairs of animals lead to changes in behavior that mark the formation of a dominance hierarchy. Those changes in behavior result from changes in the excitability of specific neural circuits. In the new subordinate, circuits for offensive behavior become less excitable and those for defensive behavior become more excitable. Serotonin, which is implicated in mechanisms for social dominance in many animals, modulates circuits for escape and avoidance responses in crayfish. The modulatory effects of serotonin on the escape circuits have been found to change with social dominance, becoming excitatory in dominant crayfish and inhibitory in subordinates. These changes in serotonin's effects on escape affect the synaptic response to sensory input of a single cell, the lateral giant (LG) command neuron for escape. Moreover, these changes occur over a 2-week period and for the subordinate are reversible at any time following a reversal of the animal's status. The results have suggested that a persistent change in social status leads to a gradual change in the expression of serotonin receptors to a pattern that is more appropriate for the new status. To test that hypothesis, the expression patterns of crayfish serotonin receptors must be compared in dominant and subordinate animals. Two of potentially five serotonin receptors in crayfish have been cloned, sequenced, and pharmacologically characterized. Measurements of receptor expression in the whole CNS of dominant and subordinate crayfish have produced inconclusive results, probably because each receptor is widespread in the nervous system and is likely to experience opposite expression changes in different areas of the CNS. Both receptors have recently been found in identified neurons that mediate escape responses, and so the next step will be to measure their expression in these identified cells in dominant and subordinate animals. |
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Department of Biology, Georgia State University, Atlanta, GA 30302, USA |
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0070-2153 |
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PMID:16860668 |
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no |
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Equine Behaviour @ team @ |
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4364 |
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Author |
Barrey, E.; Desliens, F.; Poirel, D.; Biau, S.; Lemaire, S.; Rivero, J.L.L.; Langlois, B. |
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Title |
Early evaluation of dressage ability in different breeds |
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Journal Article |
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Year |
2002 |
Publication |
Equine Veterinary Journal. Supplement |
Abbreviated Journal |
Equine Vet J Suppl |
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Volume |
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Issue |
34 |
Pages |
319-324 |
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Keywords |
Animals; Biomechanics; Breeding; Discriminant Analysis; Female; Forelimb; Gait/genetics/*physiology; Hindlimb; Horses/anatomy & histology/*genetics/*physiology; Male; Photography/veterinary; *Physical Conditioning, Animal; Sports |
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Abstract |
Dressage is one of the Olympic equestrian sports practiced in several countries using different horse breeds. Specific characteristics of the walk, trot and canter are required for dressage. It has been assumed that some of these traits could be selected for genetically and contribute to dressage performance. The purpose of this study was to compare the walk, trot and conformation characteristics in young horses of different breeds used for dressage. A total of 142 horses age 3 years were classified into 3 groups of breeds (German, French and Spanish saddle horses) and tested using the same procedure. The skeletal conformation measurements were made by image analysis. Gait variables of the walk and trot were measured by the accelerometric gait analysis system Equimetrix. Discriminant analysis could explain the variability between the groups by taking into account the walk (P<0.0003), trot (P<0.0001) and conformation variables (P<0.0001). Many gait and conformation variables were significantly different between the breeds. In summary, the German horses had gait characteristics more adapted for dressage competition, and the results of this group could be used as a reference for early evaluation in dressage. Purebred Spanish horses could be considered as a reference for collected gaits used for farm work and old academic dressage. The gait and conformation tests could be applied in a breeding or crossing plan to detect more accurately young horses with good dressage ability. |
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INRA, Station de Genetique Quantitative et Appliquee, Groupe Cheval, Jouy-en-Josas, France |
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PMID:12405708 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3726 |
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Author |
Ricard, A.; Chanu, I. |
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Title |
Genetic parameters of eventing horse competition in France |
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Journal Article |
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Year |
2001 |
Publication |
Genetics, Selection, Evolution. : GSE |
Abbreviated Journal |
Genet Sel Evol |
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33 |
Issue |
2 |
Pages |
175-190 |
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Animals; Behavior, Animal; Female; France; Genotype; Horses/*genetics; Male; Physical Conditioning, Animal; Selection (Genetics); *Sports; Stereotyped Behavior |
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Genetic parameters of eventing horse competitions were estimated. About 13 000 horses, 30 000 annual results during 17 years and 110 000 starts in eventing competitions during 8 years were recorded. The measures of performance were logarithmic transformations of annual earnings, annual earnings per start, and annual earnings per place, and underlying variables responsible for ranks in each competition. Heritabilities were low (0.11 / 0.17 for annual results, 0.07 for ranks). Genetic correlations between criteria were high (greater than 0.90) except between ranks and earnings per place (0.58) or per start (0.67). Genetic correlations between ages (from 5 to 10 years old) were also high (more than 0.85) and allow selection on early performances. The genetic correlation between the results in different levels of competition (high/international and low/amateur) was near 1. Genetic correlations of eventing with other disciplines, which included partial aptitude needed for eventing, were very low for steeplechase races (0.18) and moderate with sport: jumping (0.45), dressage (0.58). The results suggest that selection on jumping performance will lead to some positive correlated response for eventing performance, but much more response could be obtained if a specific breeding objective and selection criteria were developed for eventing. |
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Institut national de la recherche agronomique, Station de genetique quantitative et appliquee, 78352 Jouy-en-Josas Cedex, France. ugenata@dga.inra.fr |
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0999-193X |
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PMID:11333833 |
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Equine Behaviour @ team @ |
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3728 |
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Yokoyama, S.; Radlwimmer, F.B. |
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Title |
The molecular genetics of red and green color vision in mammals |
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Journal Article |
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Year |
1999 |
Publication |
Genetics |
Abbreviated Journal |
Genetics |
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Volume |
153 |
Issue |
2 |
Pages |
919-932 |
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Keywords |
Amino Acid Sequence; Animals; Base Sequence; COS Cells; Cats; Color Perception/*genetics; DNA Primers; Deer; Dolphins; *Evolution, Molecular; Goats; Guinea Pigs; Horses; Humans; Mammals/*genetics/physiology; Mice; Molecular Sequence Data; Opsin/biosynthesis/chemistry/*genetics; *Phylogeny; Rabbits; Rats; Recombinant Proteins/biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; Sciuridae; Sequence Alignment; Sequence Homology, Amino Acid; Transfection |
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Abstract |
To elucidate the molecular mechanisms of red-green color vision in mammals, we have cloned and sequenced the red and green opsin cDNAs of cat (Felis catus), horse (Equus caballus), gray squirrel (Sciurus carolinensis), white-tailed deer (Odocoileus virginianus), and guinea pig (Cavia porcellus). These opsins were expressed in COS1 cells and reconstituted with 11-cis-retinal. The purified visual pigments of the cat, horse, squirrel, deer, and guinea pig have lambdamax values at 553, 545, 532, 531, and 516 nm, respectively, which are precise to within +/-1 nm. We also regenerated the “true” red pigment of goldfish (Carassius auratus), which has a lambdamax value at 559 +/- 4 nm. Multiple linear regression analyses show that S180A, H197Y, Y277F, T285A, and A308S shift the lambdamax values of the red and green pigments in mammals toward blue by 7, 28, 7, 15, and 16 nm, respectively, and the reverse amino acid changes toward red by the same extents. The additive effects of these amino acid changes fully explain the red-green color vision in a wide range of mammalian species, goldfish, American chameleon (Anolis carolinensis), and pigeon (Columba livia). |
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Department of Biology, Syracuse University, Syracuse, New York 13244, USA. syokoyam@mailbox.syr.edu |
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0016-6731 |
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PMID:10511567 |
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Equine Behaviour @ team @ |
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4063 |
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Author |
Zhao, C.J.; Qin, Y.H.; Lee, X.H.; Wu, C. |
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Title |
Molecular and cytogenetic paternity testing of a male offspring of a hinny |
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Journal Article |
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Year |
2006 |
Publication |
Journal of Animal Breeding and Genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie |
Abbreviated Journal |
J Anim Breed Genet |
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123 |
Issue |
6 |
Pages |
403-405 |
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Keywords |
Animals; Cytogenetic Analysis; DNA, Mitochondrial/genetics; Equidae/*genetics; Female; Horses/genetics; Hybridization, Genetic; Male; Microsatellite Repeats; Pedigree; Protamines/genetics; Sexual Behavior, Animal |
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An alleged male foal of a female mule, whose sire and grandparents were unknown, was identified for its pedigree. Parentage testing was conducted by comparing polymorphism of 12 microsatellite DNA sites and mitochondrial D-loop sequences of the male foal and the female mule. Both the sequence analysis of species-specific DNA fragments and a cytogenetic analysis were performed to identify the species of the foal and its parents. The results showed that the alleged female mule is actually a hinny, and the male foal, which possesses 62 chromosomes, qualifies as an offspring of the female hinny and a jack donkey. |
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Equine Center, China Agricultural University, Beijing, China |
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English |
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0931-2668 |
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PMID:17177697 |
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Call Number |
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1846 |
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