Abstract: When Christopher Columbus and his men embarked on the second Colombian expedition to the New World (1493), the crew suffered from fever, respiratory symptoms and malaise. It is generally accepted that the disease was influenza. Pigs, horses and hens acquired in Gomera (Canary Islands) traveled in the same ship. The pigs may well have been the origin of the flu and the intermediary hosts for genetic recombination of other viral subtypes. The Caribbean archipelago had a large population of birds, the natural reservoir of the avian influenza virus. In this ecological scenario there was a concurrence of several biological elements that had never before coexisted in the New World: pigs, horses, the influenza virus and humans. We propose that birds are likely to have played an important role in the epidemiology of the flu occurring on the second Colombian trip, which caused a fatal demographic catastrophe, with an estimated mortality of 90% among the natives.

Abstract: Five cases with so-called “Dermato- und Enterozoenwahn” are reported, and the following themes are analysed from the “multidimensional” point of view: 1) process to build the shape of the intruder which is bothering the patients, 2) behavior against the intruding small animal and attitude towards the therapeutist; their characteristic manner to make complaints, 3) premorbid personality and 4) physical findings. In regard to one of the formation types of this disease, we have postulated through the neuropsychological analysis of case 5 (somatoparaphrenic patient) that patients of the typical cases 1, 2 and 3 suffer from a special kind of agnosia (perturbation of recognition; disturbance of aperception) in which they take their abnormal body sensations for causing by the small imaginary animals. Our cases showed the importance of a premorbid personality and present life-situations in combination with physical dissolution taking part in the pathoplastic process of this particular disease.

Abstract: The first anatomical studies were realized on the animal by Galen and Vesalius. Bourgelat created the first veterinarian school in Lyons, then in Paris where the famous dissection of a man on his horse can be seen (Fragonard). The Lafosse dynasty was interested in the study of the horse care and the painter Sollier showed the most beautiful coloured engravings about the horses. A chair of anatomy was created to compare the human and animal anatomy by the school of Jardin des Plantes en 1855.