| Records |
| Author |
Moon, C.; Baldridge, M.T.; Wallace, M.A.; Burnham, C.-A.D.; Virgin, H.W.; Stappenbeck, T.S. |
| Title |
Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation |
Type |
Journal Article |
| Year |
2015 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
521 |
Issue |
7550 |
Pages |
90-93 |
| Keywords |
Phenotype |
| Abstract |
The proliferation of genetically modified mouse models has exposed phenotypic variation between investigators and institutions that has been challenging to control1-5. In many cases, the microbiota is the presumed culprit of the variation. Current solutions to account for phenotypic variability include littermate and maternal controls or defined microbial consortia in gnotobiotic mice6,7. In conventionally raised mice, the microbiome is transmitted from the dam2,8,9. Here we show that microbially–driven dichotomous fecal IgA levels in WT mice within the same facility mimic the effects of chromosomal mutations. We observed in multiple facilities that vertically-transmissible bacteria in IgA-Low mice dominantly lowered fecal IgA levels in IgA-High mice after cohousing or fecal transplantation. In response to injury, IgA-Low mice showed increased damage that was transferable by fecal transplantation and driven by fecal IgA differences. We found that bacteria from IgA-Low mice degraded the secretory component (SC) of SIgA as well as IgA itself. These data indicate that phenotypic comparisons between mice must take into account the non-chromosomal hereditary variation between different breeders. We propose fecal IgA as one marker of microbial variability and conclude that cohousing and/or fecal transplantation enables analysis of progeny from different dams. |
| Address |
Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA. |
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Place of Publication |
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Editor |
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Language  |
eng |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0028-0836 |
ISBN |
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Medium |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
6005 |
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| Author |
van Dierendonck, M. |
| Title |
“Out of the box” – innovations and new developments in social housing for horses |
Type |
Conference Article |
| Year |
2015 |
Publication |
Proceedings of the 3. International Equine Science Meeting |
Abbreviated Journal |
Proc. 3. Int. Equine. Sci. Mtg |
| Volume |
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Issue |
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Pages |
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| Keywords |
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| Abstract |
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| Address |
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| Corporate Author |
van Dierendonck, M. |
Thesis |
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| Publisher |
xenophon Publishing |
Place of Publication |
Wald |
Editor |
Krueger, K. |
| Language |
english |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
Proc. 3. Int. Equine. Sci. Mtg |
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Series Issue |
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Edition |
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| ISSN |
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ISBN |
978-3-95625-000-2 |
Medium |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5817 |
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| Author |
Merola, I.; Lazzaroni, M.; Marshall-Pescini, S.; Prato-Previde, E. |
| Title |
Social referencing and cat–human communication |
Type |
Journal Article |
| Year |
2015 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
18 |
Issue |
3 |
Pages |
639-648 |
| Keywords |
Social referencing; Cats; Gaze alternation; Social learning; Human–cat communication |
| Abstract |
Cats’ (Felis catus) communicative behaviour towards humans was explored using a social referencing paradigm in the presence of a potentially frightening object. One group of cats observed their owner delivering a positive emotional message, whereas another group received a negative emotional message. The aim was to evaluate whether cats use the emotional information provided by their owners about a novel/unfamiliar object to guide their own behaviour towards it. We assessed the presence of social referencing, in terms of referential looking towards the owner (defined as looking to the owner immediately before or after looking at the object), the behavioural regulation based on the owner’s emotional (positive vs negative) message (vocal and facial), and the observational conditioning following the owner’s actions towards the object. Most cats (79 %) exhibited referential looking between the owner and the object, and also to some extent changed their behaviour in line with the emotional message given by the owner. Results are discussed in relation to social referencing in other species (dogs in particular) and cats’ social organization and domestication history. |
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Thesis |
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| Publisher |
Springer Berlin Heidelberg |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1435-9448 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5885 |
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| Author |
Defolie, C.; Malassis, R.; Serre, M.; Meunier, H. |
| Title |
Tufted capuchins (Cebus apella) adapt their communicative behaviour to human’s attentional states |
Type |
Journal Article |
| Year |
2015 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
18 |
Issue |
3 |
Pages |
747-755 |
| Keywords |
Gestural communication; Intentionality; Non-human primates; Social cognition; Attention; Pointing |
| Abstract |
Animal communication has become a widely studied field of research, especially because of the associated debates on the origin of human language. Due to their phylogenetic proximity with humans, non-human primates represent a suitable model to investigate the precursors of language. This study focuses on the perception of the attentional states of others, an important prerequisite to intentional communication. We investigated whether capuchins (Cebus apella) produce a learnt pointing gesture towards a hidden and unreachable food reward as a function of the attentional status of the human experimenter. For that purpose, we tested five subjects that we first trained to indicate by a pointing gesture towards the human partner the position of a reward hidden by an assistant. Then, capuchins were tested in two experimental conditions randomly ordered. In the first condition—motivation trial—the experimenter was attentive to the subject gestures and rewarded him immediately when it pointed towards the baited cylinder. During the second condition—test trial—the experimenter adopted one of the following attention states and the subject was rewarded after 10 s has elapsed, regardless of the subject’s behaviour. Five attentional states were tested: (1) experimenter absent, (2) experimenter back to the monkey, (3) experimenter’s head away, (4) experimenter watching above the monkey, and (5) experimenter watching the monkey face. Our results reveal a variation in our subjects’ communicative behaviours with a discrimination of the different postural clues (body and head orientation) available in our experimental conditions. This study suggests that capuchins can flexibly use a communicative gesture to adapt to the attentional state of their partner and provides evidence that acquired communicative gestures of monkeys might be used intentionally. |
| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Springer Berlin Heidelberg |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1435-9448 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5886 |
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| Author |
Oliva, J.L.; Rault, J.-L.; Appleton, B.; Lill, A. |
| Title |
Oxytocin enhances the appropriate use of human social cues by the domestic dog (Canis familiaris) in an object choice task |
Type |
Journal Article |
| Year |
2015 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
18 |
Issue |
3 |
Pages |
767-775 |
| Keywords |
Cognition; Cues; Dog; Oxytocin; Social |
| Abstract |
It has been postulated that the neuropeptide, oxytocin, is involved in human–dog bonding. This may explain why dogs, compared to wolves, are such good performers on object choice tasks, which test their ability to attend to, and use, human social cues in order to find hidden food treats. The objective of this study was to investigate the effect of intranasal oxytocin administration, which is known to increase social cognition in humans, on domestic dogs’ ability to perform such a task. We hypothesised that dogs would perform better on the task after an intranasal treatment of oxytocin. Sixty-two (31 males and 31 females) pet dogs completed the experiment over two different testing sessions, 5–15 days apart. Intranasal oxytocin or a saline control was administered 45 min before each session. All dogs received both treatments in a pseudo-randomised, counterbalanced order. Data were collected as scores out of ten for each of the four blocks of trials in each session. Two blocks of trials were conducted using a momentary distal pointing cue and two using a gazing cue, given by the experimenter. Oxytocin enhanced performance using momentary distal pointing cues, and this enhanced level of performance was maintained over 5–15 days time in the absence of oxytocin. Oxytocin also decreased aversion to gazing cues, in that performance was below chance levels after saline administration but at chance levels after oxytocin administration. |
| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Springer Berlin Heidelberg |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1435-9448 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5887 |
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| Author |
Takaoka, A.; Maeda, T.; Hori, Y.; Fujita, K. |
| Title |
Do dogs follow behavioral cues from an unreliable human? |
Type |
Journal Article |
| Year |
2015 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim.Cogn. |
| Volume |
18 |
Issue |
2 |
Pages |
475-483 |
| Keywords |
Dog; Dog–human interaction; Selective trust; Pointing; Object choice task |
| Abstract |
Dogs are known to consistently follow human pointing gestures. In this study, we asked whether dogs “automatically” do this or whether they flexibly adjust their behavior depending upon the reliability of the pointer, demonstrated in an immediately preceding event. We tested pet dogs in a version of the object choice task in which a piece of food was hidden in one of the two containers. In Experiment 1, Phase 1, an experimenter pointed at the baited container; the second container was empty. In Phase 2, after showing the contents of both containers to the dogs, the experimenter pointed at the empty container. In Phase 3, the procedure was exactly as in Phase 1. We compared the dogs’ responses to the experimenter’s pointing gestures in Phases 1 and 3. Most dogs followed pointing in Phase 1, but many fewer did so in Phase 3. In Experiment 2, dogs followed a new experimenter’s pointing in Phase 3 following replication of procedures of Phases 1 and 2 in Experiment 1. This ruled out the possibility that dogs simply lost motivation to participate in the task in later phases. These results suggest that not only dogs are highly skilled at understanding human pointing gestures, but also they make inferences about the reliability of a human who presents cues and consequently modify their behavior flexibly depending on the inference. |
| Address |
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| Corporate Author |
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Thesis |
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| Publisher |
Springer Berlin Heidelberg |
Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1435-9448 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5888 |
| Permanent link to this record |
