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Author |
Kordal, R.J.; Parsons, S.M. |
Title |
Liver alcohol dehydrogenase subunit equivalence studied by rapid sampling of alcohol product formed from sequentially bound [4α-3H]NADH |
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Journal Article |
Year |
1979 |
Publication |
Archives of Biochemistry and Biophysics |
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Volume |
194 |
Issue |
2 |
Pages |
439-448 |
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Abstract |
Horse liver alcohol dehydrogenase has been claimed to exhibit presteady-state “half-of-the-sites” reactivity with aromatic substrates under some circumstances. To clarify the role of half-of-the-sites reactivity in liver alcohol dehydrogenase the direct sampling of the alcohol product formed immediately after initiation of the reaction was studied using a rapid sampling device and [4α-3H]NADH. Liver alcohol dehydrogenase which contained a very low mole-ratio of [4α-3H]NADH bound to one subunit of the dimer was rapidly mixed with excess 4-(2'-imidazolylazo)benzaldehyde substrate and nonradioactive NADH to initiate the reaction, which was allowed to proceed for a short time before it was quenched. If strong HClO4 quench was used isolation of total free and bound azoalcohol product was possible. If NaOH quench was used isolation only of the azoalcohol product released by the enzyme was possible since most enzyme-bound azoalcohol was reversed back to azoaldehyde by the base. The pH-jump reversal reaction also was characterized spectroscopically by stopped flow technique. Nearly fullsites reactivity was observed for reaction in either direction. Furthermore (4α-3H]NADH bound firstly to one subunit in the dimer reacted essentially identically to NADH bound secondly to the other subunit. Thus, half-of-the-sites reactivity was not observed in these experiments nor did they give any indication of liver alcohol dehydrogenase active site nonequivalence induced by coenzyme binding or reaction. |
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refbase @ user @ |
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3983 |
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Author |
Graham, M.; Letz, R. |
Title |
Within-species variation in the development of ultrasonic signaling of preweanling rats |
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Journal Article |
Year |
1979 |
Publication |
Developmental Psychobiology |
Abbreviated Journal |
Dev Psychobiol |
Volume |
12 |
Issue |
2 |
Pages |
129-136 |
Keywords |
Animals; *Animals, Newborn; Animals, Suckling; Body Weight; Cold/adverse effects; Environment; Genotype; Individuality; Object Attachment; Rats; Stress/*physiopathology; Ultrasonics; *Vocalization, Animal |
Abstract |
The development of litter and individual differences in the rate of ultrasonic signaling of neonatal rats was studied. Systematic variations among litters and individuals emerged, without differential treatment. These differences were not correlated with variations in general development as indexed by body weight. Two experiments using a cross-fostering design showed that litter differences developed independently of variations in postnatal environment. These results indicate that the variations among litters in ultrasound rate have a prenatal, possibly genetic, etiology and may represent reliable indicants of response to environmental stress. |
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0012-1630 |
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PMID:456751 |
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Equine Behaviour @ team @ |
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4172 |
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Author |
Fiske, J.C.; Potter, G.D. |
Title |
Discrimination reversal learning in yearling horses |
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Journal Article |
Year |
1979 |
Publication |
J. Anim. Sci. |
Abbreviated Journal |
J. Anim. Sci. |
Volume |
49 |
Issue |
2 |
Pages |
583-588 |
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Twenty-six yearling horses were tested on a serial reversal learning discrimination combining spatial and brightness cues. An original discrimination of rewarded or nonrewarded stimuli was made followed by 20 daily reversals for position/brightness discrimination. Learning criteria were defined as 11 out of 12 correct, with the last eight responses all correct. Each horse was allowed 30 trials per discrimination to achieve criteria. Mean errors (ME) and mean trials (MT) required to achieve criteria were computed for each horse. A relative learning ability index (LAI) was calculated by the formula 1000/MT/ME. A daily emotionality score, based on a scale of one (tranquil) to six (very excitable) was assigned each horse each day after testing and a mean computed for each horse. A single subjective trainability score, based on a scale of one (difficult to train) to six (easy to train) was obtained for each horse from an independent trainer. Linear regression analyses for all 26 horses revealed a reduction in MT and ME (P<.01) over the 21-day test period indicating evidence of learning to learn. Differences (P<.05) were evident between sexes for MT and ME. Significant correlations between trainability scores and learning ability indices MT, ME, and LAI were evident for colts and geldings but not for fillies. Pooled data showed significant correlations between ME and trainability. There was a negative correlation (P<.05) between emotionality and trainability scores for all 26 horses, although the filly group did not exhibit significant correlation between these parameters. |
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Cited By (since 1996): 31; Export Date: 24 October 2008 |
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Admin @ knut @ |
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4583 |
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Author |
Rappolt, G. A.; John, J.; Thompson, N. S. |
Title |
Canine responses to familiar and unfamiliar humans |
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Journal Article |
Year |
1979 |
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Aggressive Behavior |
Abbreviated Journal |
Aggressive Behavior |
Volume |
5 |
Issue |
2 |
Pages |
155-161 |
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Dogs were observed during controlled approaches by their owners and by strangers. Significant differences between the dogs' responses to their owners and their responses to strangers were found. These results supported the popular belief that dogs respond differently to different persons, and not merely to different situations in which persons are usually encountered. |
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Departments of Biology and Psychology, Clark University, Worcester, Massachusetts DOI – 10.1002/1098-2337(1979)5 – 2<155 – - AID-AB2480050206>3.0.CO;2-D |
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Copyright © 1979 Wiley-Liss, Inc., A Wiley Company |
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Equine Behaviour @ team @ |
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4978 |
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Author |
Holm, S. |
Title |
A simple sequentially rejective multiple test procedure |
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Journal Article |
Year |
1979 |
Publication |
Scandinavian Journal of Statistics |
Abbreviated Journal |
Scand J Stat |
Volume |
6 |
Issue |
2 |
Pages |
65-70 |
Keywords |
statistical_tests |
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This paper presents a simple and widely applicable multiple test procedure of the sequentially rejective type, i.e. hypotheses are rejected one at a time until no further rejections can be done. It is shown that the test has a prescribed level of significance protection against error of the first kind for any combination of true hypotheses. The power properties of the test and a number of possible applications are also discussed. |
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Equine Behaviour @ team @ citeulike:4294367 |
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5005 |
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Author |
Turpeinen, O. |
Title |
Effect of cholesterol-lowering diet on mortality from coronary heart disease and other causes |
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Journal Article |
Year |
1979 |
Publication |
Circulation |
Abbreviated Journal |
Circulation |
Volume |
59 |
Issue |
1 |
Pages |
1-7 |
Keywords |
Coronary Disease/blood/*mortality/prevention & control; Dairy Products; *Dietary Fats; *Fats, Unsaturated; Finland; Humans; Hypercholesterolemia/complications/*diet therapy/mortality; Male; Middle Aged; Neoplasms/mortality |
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International statistics indicate that there is a close correlation between the consumption of saturated fats (dairy fats and meat fats) and the mortality from coronary heart disease (CHD), and this conception has been confirmed by many epidemiological studies. Such studies alone, however, cannot prove the existence of a cause-and-effect relationship between these two variables; dietary intervention trials are needed. The Finnish Mental Hospital Study was such a trial, conducted in two hospitals near Helsinki in 1959--1971. Practically total replacement of dairy fats by vegetable oils in the diets of these hospitals was followed by a substantial reduction in the mortality of men from CHD. Total mortality also appeared to be reduced. As to the causes of death other than CHD, none was significantly influenced by dietary change. This was also true for malignant neoplasms. To alleviate the burden of CHD on public health, many investigators have recommended important changes in the quantity and quality of dietary fats. |
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0009-7322 |
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PMID:758101 |
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refbase @ user @ |
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33 |
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Asa, C.S.; Goldfoot, D.A.; Ginther, O.J. |
Title |
Sociosexual behavior and the ovulatory cycle of ponies (Equus caballus) observed in harem groups |
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Journal Article |
Year |
1979 |
Publication |
Hormones and Behavior |
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Horm Behav |
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13 |
Issue |
1 |
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49-65 |
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Observations of sociosexual behavior of adult ponies, made on two harem groups (each comprised of one vasectomized male and three females), were correlated with follicular development and ovulation for a total of 15 cycles (minimum of 2 cycles per female). Mean cycle length (interovulatory interval) was found to be 19.7 days, with behavioral estrus lasting 7-8 days (5.5 days preovulatory; 2.3 days postovulatory). Estrous females typically showed increased frequencies of approaching and following the stallion, urinating, presenting, clitoral winking, and tail raising. Approaching and following the stallion appeared earlier and persisted longer than other estrous responses. Deviations from the modal estrous pattern included cycles with subestrus, continual estrus, behavioral estrus in the absence of ovulation, and displays of female mounting. Dominance tests revealed that a mare's status was unaffected by the phases of the estrous cycle. The presence of more than one estrous female affected the copulatory performance of both stallions, most notably in reduced latencies to first mount, intromission, and ejaculation, in spite of differences between the stallions in sexual vigor. Each stallion usually selected the dominant mare for copulation when there were multiple estrous females present, but mounts were not displayed exclusively to one female per test. The social testing situation made apparent the importance of use of space in sociosexual communication in this species, particularly in avoidance of the stallion by diestrous mares and standing alone or in proximity to him by estrous mares. |
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0018-506x |
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Equine Behaviour @ team @ |
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5363 |
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Author |
ANGLE M, et al |
Title |
Androgenes in feral stallions |
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Conference Volume |
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1979 |
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Symposium on the Ecology and Behavior of wild and feral Equids |
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31-38 |
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Laramie |
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from Prof. Hans Klingels Equine Reference List |
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refbase @ user @ |
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641 |
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Author |
Gates, S. |
Title |
A Study of home ranges of free ranging Exmoore ponies |
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Journal Article |
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1979 |
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Mammal Revision |
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Mamm. Rev. |
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9 |
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:3-18 |
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refbase @ user @ |
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765 |
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Asa Cs, |
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Sociosexual behavior in the domestic pony |
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Conference Article |
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1979 |
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Symposium on the Ecology and Behavior of Wild and Feral Equids |
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59-70 |
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Univ. of Wyoming. |
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Laramie |
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from Professor Hans Klingels Equine Reference List |
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900 |
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