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Author |
Wilson, M.T.; Ranson, R.J.; Masiakowski, P.; Czarnecka, E.; Brunori, M. |
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Title  |
A kinetic study of the pH-dependent properties of the ferric undecapeptide of cytochrome c (microperoxidase) |
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Journal Article |
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Year |
1977 |
Publication |
European Journal of Biochemistry / FEBS |
Abbreviated Journal |
Eur J Biochem |
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Volume |
77 |
Issue |
1 |
Pages |
193-199 |
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Keywords |
Animals; Cyanides; *Cytochrome c Group/metabolism; Ferric Compounds; Horses; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Mathematics; Myocardium/enzymology; *Oligopeptides/metabolism; *Peptide Fragments/metabolism; Protein Binding; Spectrophotometry; Temperature |
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Abstract |
The ferric form of the haem undecapeptide, derived from horse cytochrome c by peptic digestion, undergoes at least three pH-induced transitions with pK values of 3.4, 5.8 and 7.6. Temperature-jump experiments suggest that the first of these is due to the binding of a deprotonated imidazole group to the feric iron while the second and third arise from the binding of the two available amino groups present (the alpha-NH2 of valine and the epsilon-NH2 of lysine). Molecular models indicate that steric retraints on the peptide dictate that these amino groups may only coordinate to iron atoms via intermolecular bonds, thus leading to the polymerization of the peptide. Cyanide binding studies are in agreement with these conclusions and also yield a value of 3.6 X 10(6) M-1 s-1 for the intrinsic combination constant of CN- anion with the haem. A model is proposed which describes the pH-dependent properties of the ferric undecapeptide. |
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0014-2956 |
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PMID:20304 |
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Call Number |
Equine Behaviour @ team @ |
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3814 |
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Author |
Seyfarth, R.M. |
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Title |
A model of social grooming among adult female monkeys |
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Journal Article |
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Year |
1977 |
Publication |
Journal of Theoretical Biology |
Abbreviated Journal |
J. Theor. Biol. |
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Volume |
65 |
Issue |
4 |
Pages |
671-698 |
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Keywords |
Animals; Behavior, Animal; Female; *Grooming; Haplorhini/*physiology; *Models, Biological; Reproduction; Social Dominance; Time Factors |
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Abstract |
Grooming networks among adult female monkeys exhibit two similar features across a number of different species. High-ranking animals receive more grooming than others, and the majority of grooming occurs between females of adjacent rank. A theoretical model which duplicates these features is presented, and the properties of the model are used to explain the possible causation and function of female grooming behaviour. The model illustrates how relatively simple principles governing the behaviour of individuals may be used to explain more complex aspects of the social structure of non-human primate groups. |
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0022-5193 |
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PMID:406485 |
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Call Number |
Equine Behaviour @ team @ |
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5259 |
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Author |
Bard Jbl, |
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Title |
A unity underlying the different zebra stripping patterns |
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Journal Article |
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Year |
1977 |
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J Zool Lond |
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Volume |
183 |
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Pages |
527-539 |
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Notes |
from Professor Hans Klingels Equine Reference List |
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no |
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Call Number |
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Serial |
923 |
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Author |
Anderson , M.C.; Shettleworth, S.J. |
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Title |
Behavioral adaptation to fixed-interval and fixed-time food delivery in golden hamsters |
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Journal Article |
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Year |
1977 |
Publication |
Journal of the Experimental Analysis of Behavior (JEAB) |
Abbreviated Journal |
J Exp Anal Behav |
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27 |
Issue |
1 |
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33-49 |
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Abstract |
Food-deprived golden hamsters in a large enclosure received food every 30 sec contingent on lever pressing, or free while their behavior was continuously recorded in terms of an exhaustive classification of motor patterns. As with other species in other situations, behavior became organized into two main classes. One (terminal behaviors) increased in probability throughout interfood intervals; the other (interim behaviors) peaked earlier in interfood intervals. Which class an activity belonged to was independent of whether food was contingent on lever pressing. When food was omitted on some of the intervals (thwarting), the terminal activities began sooner in the next interval, and different interim activities changed in different ways. The interim activities did not appear to be schedule-induced in the usual sense. Rather, the hamsters left the area of the feeder when food was not due and engaged in activities they would normally perform in the experimental environment. |
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0022-5002 |
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PMID:16811980 |
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Call Number |
refbase @ user @ |
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388 |
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Author |
Fretz Pb, |
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Title |
Behavioral virilization in a brood mare |
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Journal Article |
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Year |
1977 |
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Abbreviated Journal |
Appl Anim Ethol |
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3 |
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Pages |
277-280 |
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Notes |
from Professor Hans Klingels Equine Reference List |
Approved |
no |
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Call Number |
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Serial |
1097 |
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Author |
Klingel H, |
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Title |
Communication in Perissodactyla |
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Book Chapter |
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Year |
1977 |
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Abbreviated Journal |
in Sebeok TA (ed): How Animals Communicate |
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715-727, |
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from Professor Hans Klingels Equine Reference List |
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no |
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1305 |
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Author |
Zeeb K, |
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Title |
Comparison du comportement des chevaux et des resultats du dressage au cirque |
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Journal Article |
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Year |
1977 |
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Abbreviated Journal |
Ann Med Vet |
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121 |
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37-38 |
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from Professor Hans Klingels Equine Reference List |
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no |
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1749 |
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Author |
Owaga Ml, |
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Title |
Comparison of analysis of stomach contents and feacal samples from zebra |
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Journal Article |
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Year |
1977 |
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Abbreviated Journal |
E Afr Wildl J |
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15 |
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Pages |
217-222 |
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from Professor Hans Klingels Equine Reference List |
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no |
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1446 |
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Author |
Tsong, T.Y. |
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Title |
Conformational relaxations of urea- and guanidine hydrochloride-unfolded ferricytochrome c |
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Journal Article |
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Year |
1977 |
Publication |
The Journal of Biological Chemistry |
Abbreviated Journal |
J Biol Chem |
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Volume |
252 |
Issue |
24 |
Pages |
8778-8780 |
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Keywords |
*Cytochrome c Group; Guanidines/*pharmacology; Protein Conformation/drug effects; Spectrometry, Fluorescence; Urea/*pharmacology |
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Abstract |
Several recent studies of protein the unfolded proteins. In urea- and guanidine HCl-unfolded ferricytochrome c (horse heart), an acid-induced spin state transformation of the heme group has been detected by the heme absorptions, Trp-59 fluorescence, and the intrinsic viscosity of protein. Kinetics of this second conformational transition, by the temperature jump and stopped flow methods, are complex. One rapid reaction (tau1), pH-independent, occurs in a 50-mus range; the second reaction (tau2), in a 1-ms range, depends linearly upon pH and is faster at the alkaline side; a third reaction (tau3), in a 1-s range, shows a sigmoidal transition at pH 5.1 and is faster at the acidic side. The results are consistent with a kinetic scheme which involves protein conformational changes in the transformation of the heme coordination state. The kinetics, along with previous equilibrium studies, indicate that ligand or charge interactions within a protein molecule are not completely prohibited even in strongly denaturing conditions, such as in high concentrations of urea and guanidine HCl. Thus, local structures of peptide chain associated with these interactions can exist in the unfolded protein. |
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0021-9258 |
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PMID:200618 |
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Call Number |
refbase @ user @ |
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3882 |
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Author |
Francis-Smith, K.; Wood-Gush, D.G.M. |
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Title |
Copropgagia as seen in thoroughbred foals |
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Journal Article |
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Year |
1977 |
Publication |
Equine veterinary journal |
Abbreviated Journal |
Equine Vet J |
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Volume |
9 |
Issue |
3 |
Pages |
155-157 |
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Keywords |
animal; article; coprophagy; defecation; eating; female; horse; horse disease; human; mastication |
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Abstract |
Four Thoroughbred foals were seen to quickly eat part of the faeces deposited by their own dams on some 40 per cent of the mare-defaecating occasions observed between the second and fifth week after birth. They did not do it before or after this period. This behaviour was thought to be a feeding pattern which formed a normal part of the foal's development. |
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from Professor Hans Klingels Equine Reference List |
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Call Number |
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1090 |
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