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Author Schmoldt, A.; Benthe, H.F.; Haberland, G. openurl 
  Title Digitoxin metabolism by rat liver microsomes Type Journal Article
  Year 1975 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol  
  Volume 24 Issue 17 Pages 1639-1641  
  Keywords Animals; Chromatography, Thin Layer; Digitoxigenin/metabolism; Digitoxin/*metabolism; Hydroxylation; Male; Microsomes, Liver/*metabolism; NADP/metabolism; Rats; Time Factors  
  Abstract  
  Address (up)  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0006-2952 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:10 Approved no  
  Call Number Admin @ knut @ Serial 20  
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Author Jallon, J.M.; Risler, Y.; Iwatsubo, M. openurl 
  Title Beef liver L-Glutamate dehydrogenase mechanism: presteady state study of the catalytic reduction of 2.oxoglutarate by NADPH Type Journal Article
  Year 1975 Publication Biochemical and biophysical research communications Abbreviated Journal Biochem Biophys Res Commun  
  Volume 67 Issue 4 Pages 1527-1536  
  Keywords Animals; Cattle; Glutamate Dehydrogenase/*metabolism; Ketoglutaric Acids; Kinetics; Liver/*enzymology; Nadp; Oxidation-Reduction; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet  
  Abstract  
  Address (up)  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0006-291X ISBN Medium  
  Area Expedition Conference  
  Notes PMID:1038 Approved no  
  Call Number Admin @ knut @ Serial 21  
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Author Rodier, F. openurl 
  Title [Spectral properties of porcine plasminogen: study of the acidic transition (author's transl)] Type Journal Article
  Year 1976 Publication European journal of biochemistry / FEBS Abbreviated Journal Eur J Biochem  
  Volume 63 Issue 2 Pages 553-562  
  Keywords Animals; Binding Sites; Guanidines; Hydrogen-Ion Concentration; *Plasminogen; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Swine; Temperature  
  Abstract The acidic transition of porcine plasminogen, prepared by affinity chromatography, was studied by non-destructive methods. These methods are based on the analysis of the behaviour of the tryptophyls under various conditions. The perturbation of the absorption and emission spectra by pH or temperature and the dynamic quenching of the intrinsic fluorescence are used to obtain information on structural changes which affect the environment of these residues. It is shown that by decreasing pH the fluorescence emission spectra are shifted toward the long wavelengths, with a broadening of the fluorescence band. The same effect can be obtained at constant pH by heating the protein solution. In order to analyze these phenomena, it is assumed that the fluorescence intensities at 355 nm and 328 nm reflect the proportion of the tryptophans which are exposed to the solvent, and buried, respectively. The plot of the ratio of the fluorescence intensities at these wavelengths versus pH or temperature leads to a titration curve showing an unmasking of tryptophans. The proportion of exposed tryptophans is measured by the dynamic fluorescence quenching technique and the data analyzed according to Lehrer. The plot of the fraction of exposed tryptophyls versus pH also shows the unmasking of these chromophores. Thermal perturbation of a solution of plaminogen at neutral pH induces a difference absorption spectrum whose amplitudes at the maxima are proportional to the number of exposed aromatic residues. The comparison with a solution of fully denatured plasminogen in 6 M guanidium chloride, where all the tryptophyls are exposed, shows that the percentage of exposure is equal to 59%. This number is significantly higher than the percentage found by the fluorescence quenching technique (20%), indicating that some tryptophyls are located in crevices, exposed to the solvent but not to the iodide. At acidic pH the absorption difference spectra induced by thermal perturbation are not classical, since they show an inversion and a new band between 300 nm and 305 nm. This band is mentioned in the literature as a minor band of tryptophan which appears when this chromophore is located in an asymmetric environment. On plotting the maximum amplitude of these spectra obtained at acidic pH versus temperature, we obtain a curve indicating that two types of antagonistic interactions are involved in the perturbation of the chromophores spectra. The spectrophotometric titration of plasminogen gives classical absorption difference spectra. By plotting the maximum amplitude at 292 nm versus pH, we obtain a titration curve with an apparent pK of 2.9 units. This pK is acidic which respect to the pK value of a normal carboxyl. This low value can be due to a positively charged group in the neighbourhood of a carboxyl, which interacts with one or more chromophores. When the carboxyl becomes protonated, this positively charged group is free and available to perturb the environment of some chromophores...  
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  Publisher Place of Publication Editor  
  Language French Summary Language Original Title Proprietes spectrales du plasminogene porcin. Etude de la transition acide  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0014-2956 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:4326 Approved no  
  Call Number Admin @ knut @ Serial 22  
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Author Turpeinen, O. openurl 
  Title Effect of cholesterol-lowering diet on mortality from coronary heart disease and other causes Type Journal Article
  Year 1979 Publication Circulation Abbreviated Journal Circulation  
  Volume 59 Issue 1 Pages 1-7  
  Keywords Coronary Disease/blood/*mortality/prevention & control; Dairy Products; *Dietary Fats; *Fats, Unsaturated; Finland; Humans; Hypercholesterolemia/complications/*diet therapy/mortality; Male; Middle Aged; Neoplasms/mortality  
  Abstract International statistics indicate that there is a close correlation between the consumption of saturated fats (dairy fats and meat fats) and the mortality from coronary heart disease (CHD), and this conception has been confirmed by many epidemiological studies. Such studies alone, however, cannot prove the existence of a cause-and-effect relationship between these two variables; dietary intervention trials are needed. The Finnish Mental Hospital Study was such a trial, conducted in two hospitals near Helsinki in 1959--1971. Practically total replacement of dairy fats by vegetable oils in the diets of these hospitals was followed by a substantial reduction in the mortality of men from CHD. Total mortality also appeared to be reduced. As to the causes of death other than CHD, none was significantly influenced by dietary change. This was also true for malignant neoplasms. To alleviate the burden of CHD on public health, many investigators have recommended important changes in the quantity and quality of dietary fats.  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0009-7322 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:758101 Approved no  
  Call Number refbase @ user @ Serial 33  
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Author Houpt, K.A. openurl 
  Title New perspectives on equine stereotypic behaviour Type Editorial
  Year 1995 Publication Equine veterinary journal Abbreviated Journal Equine Vet J  
  Volume 27 Issue 2 Pages 82-83  
  Keywords Animals; Horses/*psychology; Stereotyped Behavior/*physiology  
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  Address (up)  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:7607153 Approved no  
  Call Number refbase @ user @ Serial 34  
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Author Krzeminska, W. openurl 
  Title [The child learns about the world] Type Journal Article
  Year 1979 Publication Pielegniarka i polozna Abbreviated Journal Pieleg Polozna  
  Volume Issue 7 Pages 24-25  
  Keywords Child; *Child Development; Child, Preschool; Humans; *Learning  
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  Language Polish Summary Language Original Title Dziecko poznaje swiat  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0048-4148 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:260249 Approved no  
  Call Number refbase @ user @ Serial 43  
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Author Houpt, K.A. openurl 
  Title Stable vices and trailer problems Type Journal Article
  Year 1986 Publication The Veterinary clinics of North America. Equine practice Abbreviated Journal Vet Clin North Am Equine Pract  
  Volume 2 Issue 3 Pages 623-633  
  Keywords Aerophagy/veterinary; Aggression; Animals; *Animals, Domestic; *Behavior, Animal; Fear; Frustration; Habits; *Horses; Locomotion; Mastication; Social Environment; Transportation  
  Abstract Stable vices include oral vices such as cribbing, wood chewing, and coprophagia, as well as stall walking, weaving, pawing, and stall kicking. Some of these behaviors are escape behaviors; others are forms of self-stimulation. Most can be eliminated by pasturing rather than stall confinement. Trailering problems include failure to load, scrambling in the moving trailer, struggling in the stationary trailer, and refusal to unload. Gradual habituation to entering the trailer, the presence of another horse, or a change in trailer type can be used to treat these problems.  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0749-0739 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:3492249 Approved no  
  Call Number refbase @ user @ Serial 48  
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Author Crowell-Davis, S.L.; Houpt, K.A. openurl 
  Title Maternal behavior Type Journal Article
  Year 1986 Publication The Veterinary clinics of North America. Equine practice Abbreviated Journal Vet Clin North Am Equine Pract  
  Volume 2 Issue 3 Pages 557-571  
  Keywords Aggression; Animals; Animals, Wild; Female; *Horses; Lactation; *Maternal Behavior; Pregnancy; *Pregnancy, Animal; Rejection (Psychology)  
  Abstract Parturition in mares is rapid and is followed by a brief period of sensitivity to imprinting on a foal. There is large individual variation in normal maternal style, but normal mothers actively defend their foal, remain near the foal when it is sleeping, tolerate or assist nursing, and do not injure their own foal. Disturbance of a mare and foal during the early imprinting period can predispose a mare to rejection of her foal; therefore, it should be avoided. There are a variety of forms of foal rejection and numerous etiologies. Therefore, each case should be evaluated individually.  
  Address (up)  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0749-0739 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:3492245 Approved no  
  Call Number refbase @ user @ Serial 49  
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Author Crowell-Davis, S.L.; Houpt, K.A. openurl 
  Title Techniques for taking a behavioral history Type Journal Article
  Year 1986 Publication The Veterinary clinics of North America. Equine practice Abbreviated Journal Vet Clin North Am Equine Pract  
  Volume 2 Issue 3 Pages 507-518  
  Keywords Animals; *Behavior, Animal; Cooperative Behavior; *Horses; Maternal Behavior  
  Abstract A thorough behavioral history is essential for adequate assessment of a given case. In reviewing the chief complaint, a description of what actually happened, rather than the owner's interpretation of what happened, is required. Other behavior problems, environment, rearing history, and training need to be reviewed. Sample question sets for some common problems are given.  
  Address (up)  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0749-0739 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:3492242 Approved no  
  Call Number refbase @ user @ Serial 50  
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Author Youket, R.J.; Carnevale, J.M.; Houpt, K.A.; Houpt, T.R. openurl 
  Title Humoral, hormonal and behavioral correlates of feeding in ponies: the effects of meal frequency Type Journal Article
  Year 1985 Publication Journal of animal science Abbreviated Journal J. Anim Sci.  
  Volume 61 Issue 5 Pages 1103-1110  
  Keywords Animals; Behavior, Animal/physiology; Blood Glucose/*analysis; Blood Proteins/*analysis; Blood Volume; *Eating; Feeding Behavior/physiology; Female; Heart Rate; Horses/blood/*physiology; Male; Osmolar Concentration; Osmotic Pressure; Triiodothyronine/*blood  
  Abstract The effect of meal frequency on body fluid, glucose, triiodothyronine (T3), heart rate and behavior was measured in 10 ponies. A simple reversal design was used in which each pony received one meal/day (1X) for 2 wk and six meals/day (6X) for 2 wk. The total intake/day was held constant. Feeding was followed by a rise in plasma levels of glucose, T3, protein and osmolality. One large meal was followed by significantly greater changes in all of the variables than was a meal one-sixth the size. Plasma T3 rose from 41 +/- 5 (SE) ng/liter before feeding to 43 +/- 5 ng/liter following a small meal, but rose significantly higher, from 39 +/- 4 to 60 +/- 10 ng/liter, following a large meal. Glucose rose from 84 +/- 3 to 109 +/- 7 mg/dl following a small meal and rose significantly higher, from 83 +/- 3 to 154 +/- 11 mg/dl, after a large meal. Plasma protein rose from 6.55 +/- .14 to 6.62 +/- .16 g/dl following a small meal and from 6.45 +/- .14 to 6.99 +/- .11 g/dl following a large meal. Osmolality rose from 227 +/- 1 mosmol/liter before to 279 +/- 1 mosmol/liter following a small meal and significantly higher from 278 +/- 2 to 285 +/- 1 mosnol/liter following a large meal. Heart rate rose from 42 beats/min in the absence of feed to 50 beats/min when food was visible to the ponies and did not rise higher when eating began. There were no significant differences in the cardiac response to one large meal and that to a small meal.(ABSTRACT TRUNCATED AT 250 WORDS)  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0021-8812 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:4077755 Approved no  
  Call Number refbase @ user @ Serial 51  
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