| Record |
| Author |
Blunden, A.S.; Smith, K.C.; Whitwell, K.E.; Dunn, K.A. |
| Title |
Systemic infection by equid herpesvirus-1 in a Grevy's zebra stallion (Equus grevyi) with particular reference to genital pathology |
Type |
Journal Article |
| Year |
1998 |
Publication |
Journal of Comparative Pathology |
Abbreviated Journal |
J Comp Pathol |
| Volume |
119 |
Issue |
4 |
Pages |
485-493 |
| Keywords |
Animals; Animals, Zoo; Epididymis/pathology/virology; Equidae/*virology; Herpesviridae Infections/diagnosis/pathology/*veterinary; Herpesvirus 1, Equid/isolation & purification/*pathogenicity; Lymph Nodes/pathology/virology; Male; Nasal Mucosa/pathology/virology; Pulmonary Edema/pathology; Spleen/virology; Testis/*pathology/virology |
| Abstract |
A severe multi-systemic form of equid herpesvirus-1 infection is described in an adult zebra stallion. There was multifocal necrotizing rhinitis, marked hydrothorax and pulmonary oedema, with viral antigen expression in degenerating epithelial cells, local endothelial cells and intravascular leucocytes of the nasal mucosa and lung. Specific localization of EHV-1 infection was seen in the testes and epididymides, including infection of Leydig cells and germinal epithelium, which would have facilitated venereal shedding of virus in life. The case provided a unique opportunity to study hitherto undescribed aspects of the pathogenesis of naturally occurring EHV-1 infection in the male equine genital tract. Restriction digests of the isolate demonstrated a pattern similar to that of EHV-1 isolates previously recovered from aborted zebra and onager fetuses. |
| Address |
Animal Health Trust Centre for Preventive Medicine, Newmarket, Suffolk, UK |
| Corporate Author |
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Thesis |
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| Publisher |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language  |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0021-9975 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:9839210 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2239 |
| Permanent link to this record |
