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Author (up) Blunden, A.S.; Smith, K.C.; Whitwell, K.E.; Dunn, K.A. doi  openurl
  Title Systemic infection by equid herpesvirus-1 in a Grevy's zebra stallion (Equus grevyi) with particular reference to genital pathology Type Journal Article
  Year 1998 Publication Journal of Comparative Pathology Abbreviated Journal J Comp Pathol  
  Volume 119 Issue 4 Pages 485-493  
  Keywords Animals; Animals, Zoo; Epididymis/pathology/virology; Equidae/*virology; Herpesviridae Infections/diagnosis/pathology/*veterinary; Herpesvirus 1, Equid/isolation & purification/*pathogenicity; Lymph Nodes/pathology/virology; Male; Nasal Mucosa/pathology/virology; Pulmonary Edema/pathology; Spleen/virology; Testis/*pathology/virology  
  Abstract A severe multi-systemic form of equid herpesvirus-1 infection is described in an adult zebra stallion. There was multifocal necrotizing rhinitis, marked hydrothorax and pulmonary oedema, with viral antigen expression in degenerating epithelial cells, local endothelial cells and intravascular leucocytes of the nasal mucosa and lung. Specific localization of EHV-1 infection was seen in the testes and epididymides, including infection of Leydig cells and germinal epithelium, which would have facilitated venereal shedding of virus in life. The case provided a unique opportunity to study hitherto undescribed aspects of the pathogenesis of naturally occurring EHV-1 infection in the male equine genital tract. Restriction digests of the isolate demonstrated a pattern similar to that of EHV-1 isolates previously recovered from aborted zebra and onager fetuses.  
  Address Animal Health Trust Centre for Preventive Medicine, Newmarket, Suffolk, UK  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0021-9975 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:9839210 Approved no  
  Call Number Equine Behaviour @ team @ Serial 2239  
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