| Records |
| Author |
Chittka, L.; Dyer, A. |
| Title |
Cognition: Your face looks familiar |
Type |
Journal Article |
| Year |
2012 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
481 |
Issue |
7380 |
Pages |
154-155 |
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Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved. |
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| ISSN |
0028-0836 |
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| Notes |
10.1038/481154a |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
5494 |
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| Author |
Moon, C.; Baldridge, M.T.; Wallace, M.A.; Burnham, C.-A.D.; Virgin, H.W.; Stappenbeck, T.S. |
| Title |
Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation |
Type |
Journal Article |
| Year |
2015 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
521 |
Issue |
7550 |
Pages |
90-93 |
| Keywords |
Phenotype |
| Abstract |
The proliferation of genetically modified mouse models has exposed phenotypic variation between investigators and institutions that has been challenging to control1-5. In many cases, the microbiota is the presumed culprit of the variation. Current solutions to account for phenotypic variability include littermate and maternal controls or defined microbial consortia in gnotobiotic mice6,7. In conventionally raised mice, the microbiome is transmitted from the dam2,8,9. Here we show that microbially–driven dichotomous fecal IgA levels in WT mice within the same facility mimic the effects of chromosomal mutations. We observed in multiple facilities that vertically-transmissible bacteria in IgA-Low mice dominantly lowered fecal IgA levels in IgA-High mice after cohousing or fecal transplantation. In response to injury, IgA-Low mice showed increased damage that was transferable by fecal transplantation and driven by fecal IgA differences. We found that bacteria from IgA-Low mice degraded the secretory component (SC) of SIgA as well as IgA itself. These data indicate that phenotypic comparisons between mice must take into account the non-chromosomal hereditary variation between different breeders. We propose fecal IgA as one marker of microbial variability and conclude that cohousing and/or fecal transplantation enables analysis of progeny from different dams. |
| Address |
Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA. |
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eng |
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0028-0836 |
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no |
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Equine Behaviour @ team @ |
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6005 |
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Karenina, K.; Giljov, A.; Ingram, J.; Rowntree, V.J.; Malashichev, Y. |
| Title |
Lateralization of mother�infant interactions in a diverse range of mammal species |
Type |
Journal Article |
| Year |
2017 |
Publication |
Nature Ecology & Evolution |
Abbreviated Journal |
Nat Ecol Evol |
| Volume |
1 |
Issue |
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Pages |
0030 Ep - |
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| Abstract |
Left-cradling bias is a distinctive feature of maternal behaviour in humans and great apes, but its evolutionary origin remains unknown. In 11 species of marine and terrestrial mammal, we demonstrate consistent patterns of lateralization in mother�infant interactions, indicating right hemisphere dominance for social processing. In providing clear evidence that lateralized positioning is beneficial in mother�infant interactions, our results illustrate a significant impact of lateralization on individual fitness. |
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Nature Publishing Group SN - |
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Equine Behaviour @ team @ |
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6040 |
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Devinsky, O.; Boesch, J.M.; Cerda-Gonzalez, S.; Coffey, B.; Davis, K.; Friedman, D.; Hainline, B.; Houpt, K.; Lieberman, D.; Perry, P.; Prüss, H.; Samuels, M.A.; Small, G.W.; Volk, H.; Summerfield, A.; Vite, C.; Wisniewski, T.; Natterson-Horowitz, B. |
| Title |
A cross-species approach to disorders affecting brain and behaviour |
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Journal Article |
| Year |
2018 |
Publication |
Nature Reviews Neurology |
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Structural and functional elements of biological systems are highly conserved across vertebrates. Many neurological and psychiatric conditions affect both humans and animals. A cross-species approach to the study of brain and behaviour can advance our understanding of human disorders via the identification of unrecognized natural models of spontaneous disorders, thus revealing novel factors that increase vulnerability or resilience, and via the assessment of potential therapies. Moreover, diagnostic and therapeutic advances in human neurology and psychiatry can often be adapted for veterinary patients. However, clinical and research collaborations between physicians and veterinarians remain limited, leaving this wealth of comparative information largely untapped. Here, we review pain, cognitive decline syndromes, epilepsy, anxiety and compulsions, autoimmune and infectious encephalitides and mismatch disorders across a range of animal species, looking for novel insights with translational potential. This comparative perspective can help generate novel hypotheses, expand and improve clinical trials and identify natural animal models of disease resistance and vulnerability. |
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1759-4766 |
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no |
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Equine Behaviour @ team @ Devinsky2018 |
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6420 |
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| Author |
Henry, S.; Fureix, C.; Rowberry, R.; Bateson, M.; Hausberger, M. |
| Title |
Do horses with poor welfare show 'pessimistic' cognitive biases? |
Type |
Journal Article |
| Year |
2017 |
Publication |
The Science of Nature |
Abbreviated Journal |
Sci. Nat. |
| Volume |
104 |
Issue |
1 |
Pages |
8 |
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| Abstract |
This field study tested the hypothesis that domestic horses living under putatively challenging-to-welfare conditions (for example involving social, spatial, feeding constraints) would present signs of poor welfare and co-occurring pessimistic judgement biases. Our subjects were 34 horses who had been housed for over 3 years in either restricted riding school situations (e.g. kept in single boxes, with limited roughage, ridden by inexperienced riders; N = 25) or under more naturalistic conditions (e.g. access to free-range, kept in stable social groups, leisure riding; N = 9). The horses' welfare was assessed by recording health-related, behavioural and postural indicators. Additionally, after learning a location task to discriminate a bucket containing either edible food ('positive' location) or unpalatable food ('negative' location), the horses were presented with a bucket located near the positive position, near the negative position and halfway between the positive and negative positions to assess their judgement biases. The riding school horses displayed the highest levels of behavioural and health-related problems and a pessimistic judgment bias, whereas the horses living under more naturalistic conditions displayed indications of good welfare and an optimistic bias. Moreover, pessimistic bias data strongly correlated with poor welfare data. This suggests that a lowered mood impacts a non-human species' perception of its environment and highlights cognitive biases as an appropriate tool to assess the impact of chronic living conditions on horse welfare. |
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1432-1904 |
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no |
| Call Number |
Equine Behaviour @ team @ Henry2017 |
Serial |
6665 |
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