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Author |
Alexander, F. |
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Title |
The effect of diuretics on the faecal excretion of water and electrolytes in horses |
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Journal Article |
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Year |
1977 |
Publication |
British journal of pharmacology |
Abbreviated Journal |
Br J Pharmacol |
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Volume |
60 |
Issue |
4 |
Pages |
589-593 |
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Keywords |
Animals; Body Water/*metabolism; Chlorides/metabolism; Electrolytes/*metabolism; Feces/*analysis; Furosemide/*pharmacology; Horses; Hydrochlorothiazide/*pharmacology; Male; Potassium/metabolism; Sodium/metabolism; Time Factors |
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Abstract |
1. The effect on plasma, urinary and faecal electrolytes of frusemide and hydrochlorthiazide was measured in ponies, mean weight 180 kg. 2. The rapid loss in urine of large quantities of sodium had only a small effect on plasma sodium concentration. 3. Faecal sodium excretion was increased substantially after the administration of frusemide. 4. Frusemide increased faecal potassium during the 48 h following administration and faecal water in the 24/48 h period. It also produced a hypopotassaemia. 5. Hydrochlorthiazide increased faecal chloride during the 24 h after administration. 6. Frusemide increased the intestinal transit time of both liquid (polyethylene glycol) and particulate (Cr2O3) markers. |
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English |
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0007-1188 |
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PMID:907872 |
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Call Number |
refbase @ user @ |
Serial |
111 |
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Author |
Alexander, F. |
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Title |
The effect of some anti-diarrhoeal drugs on intestinal transit and faecal excretion of water and electrolytes in the horse |
Type |
Journal Article |
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Year |
1978 |
Publication |
Equine veterinary journal |
Abbreviated Journal |
Equine Vet J |
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Volume |
10 |
Issue |
4 |
Pages |
229-234 |
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Keywords |
Animals; Antidiarrheals/*pharmacology; Atropine/pharmacology; Electrolytes/*analysis/urine; Feces/*analysis; Gastrointestinal Motility/*drug effects; Horses/*metabolism/physiology; Loperamide/pharmacology; Male; Meperidine/pharmacology; Morphine/pharmacology; Opium/pharmacology; Water/*analysis |
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Abstract |
The effect of morphine, Tinct. opii, loperamide, pethidine and atropine on intestinal transit and the faecal and urinary excretion of water and electrolytes was studied in ponies. The rate of passage of a particulate marker was slowed by morphine, hastened then slowed by loperamide and Tinct. opii, and hastened by atropine. The liquid marker was slowed by Tinct. opii and hastened then slowed by the other drugs. Only loperamide decreased the faecal sodium excretion. This drug also decreased faecal water and weight; it appeared worthy of clinical trial in diarrhoea. Tinct. opii decreased by morphine, pethidine and atropine increased faecal water. |
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0425-1644 |
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PMID:738263 |
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Call Number |
refbase @ user @ |
Serial |
110 |
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Author |
Andersson, P.; Kvassman, J.; Lindstrom, A.; Olden, B.; Pettersson, G. |
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Title |
Effect of NADH on the pKa of zinc-bound water in liver alcohol dehydrogenase |
Type |
Journal Article |
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Year |
1981 |
Publication |
European Journal of Biochemistry / FEBS |
Abbreviated Journal |
Eur J Biochem |
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Volume |
113 |
Issue |
3 |
Pages |
425-433 |
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Keywords |
Alcohol Oxidoreductases/*metabolism; Aldehydes/metabolism; Animals; Binding Sites; Cinnamates/metabolism; Horses; Hydrogen-Ion Concentration; Kinetics; Ligands; Liver/*metabolism; NAD/*metabolism; Water/metabolism; Zinc/metabolism |
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Abstract |
Equilibrium constants for coenzyme binding to liver alcohol dehydrogenase have been determined over the pH range 10--12 by pH-jump stop-flow techniques. The binding of NADH or NAD+ requires the protonated form of an ionizing group (distinct from zinc-bound water) with a pKa of 10.4. Complex formation with NADH exhibits an additional dependence on the protonation state of an ionizing group with a pKa of 11.2. The binding of trans-N,N-dimethylaminocinnamaldehyde to the enzyme . NADH complex is prevented by ionization of the latter group. It is concluded from these results that the pKa-11.2-dependence of NADH binding most likely derives from ionization of the water molecule bound at the catalytic zinc ion of the enzyme subunit. The pKa value of 11.2 thus assigned to zinc-bound water in the enzyme . NADH complex appears to be typical for an aquo ligand in the inner-sphere ligand field provided by the zinc-binding amino acid residues in liver alcohol dehydrogenase. This means that the pKa of metal-bound water in zinc-containing enzymes can be assumed to correlate primarily with the number of negatively charged protein ligands coordinated by the active-site zinc ion. |
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English |
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ISSN |
0014-2956 |
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Notes |
PMID:7011796 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3810 |
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Author |
Andrews, F.M.; Ralston, S.L.; Sommardahl, C.S.; Maykuth, P.L.; Green, E.M.; White, S.L.; Williamson, L.H.; Holmes, C.A.; Geiser, D.R. |
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Title |
Weight, water, and cation losses in horses competing in a three-day event |
Type |
Journal Article |
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Year |
1994 |
Publication |
Journal of the American Veterinary Medical Association |
Abbreviated Journal |
J Am Vet Med Assoc |
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Volume |
205 |
Issue |
5 |
Pages |
721-724 |
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Keywords |
Animals; Body Water/*metabolism; Body Weight/*physiology; Exertion/*physiology; Female; Horses/blood/*metabolism; Male; Physical Conditioning, Animal/physiology; Physical Endurance/physiology; Potassium/*blood; Sodium/*blood |
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Abstract |
Body weight of 48 horses competing in a 3-day event was measured the day before the event (baseline), following the dressage phase of the event (day 1), after the endurance phases of the event (day 2), and 18 to 24 hours after the endurance phases (day 3). Plasma sodium and potassium concentrations were measured the evening before, immediately after, and 10 minutes after the endurance phases. Total body water, water loss, and net exchangeable cation loss were then calculated. Body weight and total body water were significantly decreased, compared with baseline values, at all times during the event, and significant water loss was detected. The largest changes were recorded after the endurance phases of the event. Water deficits were still detected 18 to 24 hours after the endurance phases of the event. Mean plasma sodium concentration was significantly increased immediately after the endurance phases of the event, compared with concentration measured the evening before, and remained increased after the 10-minute recovery period, presumably because of dehydration. Mean plasma potassium concentration was significantly increased immediately after the endurance phases of the event, compared with concentration measured the evening before, but was not increased after the 10-minute recovery period. |
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Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville 37901-1071 |
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English |
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ISSN |
0003-1488 |
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Notes |
PMID:7989242 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3745 |
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Author |
Beerwerth, W.; Schurmann, J. |
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Title |
[Contribution to the ecology of mycobacteria] |
Type |
Journal Article |
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Year |
1969 |
Publication |
Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. 1. Abt. Medizinisch-Hygienische Bakteriologie, Virusforschung und Parasitologie. Originale |
Abbreviated Journal |
Zentralbl Bakteriol [Orig] |
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Volume |
211 |
Issue |
1 |
Pages |
58-69 |
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Keywords |
*Animal Feed; Animals; Cattle; Chickens; Ecology; Feces/*microbiology; *Food Microbiology; Germany, West; Horses; Hydroxides; Mycobacterium/classification/*isolation & purification; Mycobacterium tuberculosis/isolation & purification; Oxalates; *Sewage; Sheep; Sodium; *Soil Microbiology; Swine; *Water Microbiology |
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German |
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Original Title |
Zur Okologie der Mykobakterien |
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ISSN |
0372-8110 |
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Notes |
PMID:4989344 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2743 |
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Author |
Birch, H.L.; Bailey, A.J.; Goodship, A.E. |
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Title |
Macroscopic 'degeneration' of equine superficial digital flexor tendon is accompanied by a change in extracellular matrix composition |
Type |
Journal Article |
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Year |
1998 |
Publication |
Equine Veterinary Journal |
Abbreviated Journal |
Equine Vet J |
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Volume |
30 |
Issue |
6 |
Pages |
534-539 |
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Keywords |
Animals; Collagen/analysis; DNA/analysis; Extracellular Matrix/*chemistry; Glycosaminoglycans/analysis; Horses/injuries/*physiology; Immunohistochemistry; Rupture/veterinary; Tendon Injuries/metabolism/pathology/veterinary; Tendons/chemistry/*pathology; Water/analysis |
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Abstract |
Injuries to the superficial digital flexor tendon are common in horses required to gallop and jump at speed. Partial rupture of this tendon usually occurs in the central core of the midmetacarpal region and may be preceded by localised degenerative changes. Post mortem examination of apparently normal equine flexor tendons has revealed an abnormal macroscopic appearance in the central core, characterised by a reddish discolouration. We have previously shown that there is also physical damage to the collagen fibres. In the present study we tested the hypothesis that the abnormal appearance is accompanied by changes in the composition of the extracellular matrix of the tendon. Biochemical analysis of the extracellular matrix demonstrated an increase in total sulphated glycosaminoglycan content, increase in the proportion of type III collagen and decrease in collagen linked fluorescence in the central core of 'degenerated' tendons relative to tissue from the peripheral region of the same tendon. Dry matter content and total collagen content were not significantly different between tendon zones or normal and 'degenerated' tendons. These changes suggest a change in cell metabolism and matrix turnover in the central core of the tendon and are likely to contribute to a decrease in mechanical properties in this part of the tendon, predisposing to the characteristic partial rupture of the tendon. |
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Veterinary Basic Sciences, Royal Veterinary College, North Mymms, Hatfield, UK |
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English |
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ISSN |
0425-1644 |
ISBN |
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Notes |
PMID:9844973 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
3794 |
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Author |
Cancedda, M. |
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Title |
[Social and behavioral organization of horses on the Giara (Sardinia): distribution and aggregation] |
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Journal Article |
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Year |
1990 |
Publication |
Bollettino della Societa italiana di biologia sperimentale |
Abbreviated Journal |
Boll Soc Ital Biol Sper |
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Volume |
66 |
Issue |
11 |
Pages |
1089-1096 |
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Keywords |
Animals; *Animals, Wild/physiology/psychology; Environment; Female; *Horses/physiology/psychology; Italy; Male; Population Density; Sexual Behavior, Animal; *Social Behavior; Social Dominance; Water |
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Abstract |
In this paper some considerations on the environment of the 42 Kmq of the volcanic-basaltic Giara tableland are discussed. Conditioning by the environment and its effect on the distribution of a population of 712 horses is illustrated in view of their social and behavioural organization. |
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Istituto di Fisiologia Generale e Speciale, Universita di Sassari |
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Italian |
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Introduzione all'organizzazione sociale e comportamentale dei cavallini sulla Giara (Sardegna): distribuzione ed aggregazione |
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0037-8771 |
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Notes |
PMID:2095819 |
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no |
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Call Number |
refbase @ user @ |
Serial |
673 |
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Author |
Domjan, M. |
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Title |
Determinants of the enhancement of flavored-water intake by prior exposure |
Type |
Journal Article |
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Year |
1976 |
Publication |
Journal of Experimental Psychology. Animal Behavior Processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
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Volume |
2 |
Issue |
1 |
Pages |
17-27 |
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Keywords |
Animals; Arousal; *Awareness; Behavior, Animal; *Cognition; *Drinking Behavior; Environment; Escape Reaction; Fear; Male; Rats; Saccharin/administration & dosage; *Taste; Thirst; Time Factors; Water Deprivation |
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Abstract |
The intake of a 2.0% sodium saccharin solution in rats was observed to increase as a function of both the number (Experiment 1) and the duration (Experiment 3) of prior periods of access to the saccharin flavor, but did not increase when subjects were maintained on a fluid deprivation procedure in the absence of saccharin exposure (Experiment 2). The enhancement of intake was further influenced by the schedule of saccharin preexposures in the absence of variations in the amount of solution tasted (Experiment 4). The effect was not a function of the opportunity for subjects to determine their own pattern of contact with the saccharin flavor, the opportunity for association of the flavor with hunger and thirst reduction, or the amount of saccharin swallowed during preexposure (Experiment 5). These results suggest that mere exposure to a flavored solution is sufficient to increase subsequent intakes. The phenomenon is discussed in terms of the attenuation of neophobia elicited by the novelty of flavored solutions. |
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0097-7403 |
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Notes |
PMID:1249524 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2790 |
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Author |
Gibson, B.M.; Shettleworth, S.J.; McDonald, R.J. |
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Title |
Finding a goal on dry land and in the water: differential effects of disorientation on spatial learning |
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Journal Article |
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Year |
2001 |
Publication |
Behavioural brain research |
Abbreviated Journal |
Behav. Brain. Res. |
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Volume |
123 |
Issue |
1 |
Pages |
103-111 |
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Keywords |
Animals; Cues; Environment; Male; Maze Learning/*physiology; Orientation/*physiology; Rats; Rats, Long-Evans; Spatial Behavior/*physiology; Water |
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Abstract |
Two previous studies, Martin et al. (J. Exp. Psychol. Anim. Behav. Process. 23 (1997) 183) and Dudchenko et al. (J. Exp. Psychol. Anim. Behav. Process. 23 (1997) 194), report that, compared to non-disoriented controls, rats disoriented before testing were disrupted in their ability to learn the location of a goal on a dry radial-arm maze task, but that both groups learned at the same rate in the Morris water maze. However, the radial-arm maze task was much more difficult than the water maze. In the current set of experiments, we examined the performance of control and disoriented rats on more comparable dry land and water maze tasks. Compared to non-disoriented rats, rats that were disoriented before testing were significantly impaired in locating a goal in a circular dry arena, but not a water tank. The results constrain theoretical explanations for the differential effects of disorientation on different spatial tasks. |
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Department of Psychology, University of Toronto, 100 St. George Street, Toronto, Ontario, Canada M5S 3G3. gibson@psych.utoronto.ca |
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0166-4328 |
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PMID:11377733 |
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Call Number |
refbase @ user @ |
Serial |
372 |
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Author |
Golynski, M.; Szczepanik, M.P.; Wilkolek, P.M.; Adamek, L.R.; Sitkowski, W.; Taszkun, I. |
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Title |
Influence of hair clipping on transepidermal water loss values in horses: a pilot study |
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Journal Article |
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Year |
2018 |
Publication |
Polish Journal of Veterinary Sciences |
Abbreviated Journal |
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vol. 21 |
Issue |
No 1 |
Pages |
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Keywords |
horses; transepidermal water loss; clipping |
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University of Warmia and Mazury in Olsztyn |
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Equine Behaviour @ team @ |
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6612 |
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