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Author |
Czerlinski, G.H.; Wagner, M.; Erickson, J.O.; Theorell, H. |
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Title |
Chemical relaxation studies on the system liver alcohol dehydrogenase, NADH and imidazole |
Type |
Journal Article |
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Year |
1975 |
Publication  |
Acta Chemica Scandinavica. Series B: Organic Chemistry and Biochemistry |
Abbreviated Journal |
Acta Chem Scand B |
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Volume |
29 |
Issue |
8 |
Pages |
797-810 |
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Keywords |
Alcohol Oxidoreductases/*metabolism; Animals; Computers; Hydrogen-Ion Concentration; Imidazoles/*metabolism; Kinetics; Liver/enzymology/*metabolism; Mathematics; Models, Chemical; NAD/*metabolism; Time Factors |
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Abstract |
Several years ago, Theorell and Czerlinski conducted experiments on the system of horse liver alcohol dehydrogenase, reduced nicotinamide adenine dinucleotide and imidazole, using the first version of the temperature jump apparatus with detection of changes in fluorescence. These early experiments were repeated with improved instrumentation and confirmed the early experiments in general terms. However, the improved detection system allowed to measure a slight concentration dependence of the relaxation time of around 3 ms. Furthermore, the chemical relaxation time was smaller than the one determined earlier (by factor 2). The data were evaluated much more rigorously than before, allowing an appropriate interpretation of the results. The observed relaxation time is largely due to rate constants in an interconversion of ternary complexes, which are faster than three (of the four) dissociation rate constants, determined previously by Theorell and McKinley-McKee.1,2 This fact contributed to earlier difficulties of finding any concentration dependence. However, the binding of imidazole to the binary enzyme-coenzyme complex can be made to couple kinetically into the interconversion rate of the two ternary complexes. The observed signal derives largely from the ternary complex(es). A substantial fluorescence signal change is associated with the observed relaxation process, suggesting a relocation of the imidazole in reference to the nicotinamide moiety of the bound coenzyme. Nine models are considered with two types of coupling of pre-equilibria (none-all). Quantitative evaluations favor the model with two ternary complexes connected by an interconversion outside the four-step (bimolecular) cycle. The ternary complex outside the cycle has much higher fluorescence yield than the one inside. The interconversion equilibrium is near unity for imidazole. If it would be shifted very much to the side of the “dead-end” complex (as in isobutyramide?!), stimulating action could not take place. |
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0302-4369 |
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PMID:882 |
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refbase @ user @ |
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3887 |
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Author |
Romano, N.; Vitale, F.; Alesi, D.R.; Bonura, F.; La Licata, R.; Intonazzo, V.; Dardanoni, G.; Mammina, C. |
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Title |
The changing pattern of human immunodeficiency virus type 1 infection in intravenous drug users. Results of a six-year seroprevalence study in Palermo, Italy |
Type |
Journal Article |
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Year |
1992 |
Publication |
American Journal of Epidemiology |
Abbreviated Journal |
Am J Epidemiol |
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Volume |
135 |
Issue |
11 |
Pages |
1189-1196 |
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Keywords |
Acquired Immunodeficiency Syndrome/*epidemiology; Adolescent; Adult; Chi-Square Distribution; Cross-Sectional Studies; Female; HIV Antibodies/blood; HIV Infections/*epidemiology; HIV Seroprevalence/*trends; *Hiv-1; Hepatitis B Antibodies/blood; Hepatitis B Surface Antigens/blood; Heroin; Humans; Incidence; Italy/epidemiology; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Prevalence; Risk Factors; Substance Abuse, Intravenous/*epidemiology; Time Factors |
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Abstract |
A cross-sectional seroepidemiologic study was carried out between 1985 and 1990 in 1,567 heterosexual intravenous drug users who had been seen at the AIDS Regional Reference Center in Palermo, Italy, to evaluate the rate of human immunodeficiency virus type 1 (HIV-1) seroprevalence in this group and its long-term trend. Sixty serum samples collected from drug users in 1980 and 1983, before the founding of the Center (1985), were tested as well. Some demographic and behavioral risk factors were studied in a subgroup of intravenous drug users enrolled in 1985, 1987, and 1990 for their possible association with HIV-1. These factors were also studied in relation to hepatitis B virus infection, since both viruses share the same modes of spread. These drug users had a higher prevalence of markers for hepatitis B virus than of HIV-1 antibodies, and the prevalence rates in sera collected declined over time for both infections. The presence of both antibodies to HIV-1 and markers for hepatitis B virus was independently associated with the age of the drug user, the duration of drug use, and the year of serum collection. Antibodies to HIV-1 were observed more frequently in females than in males. No relation was found between education or employment status and the presence of HIV-1 antibodies or hepatitis B virus markers. Although new HIV-1 infections still occur, the decline in seroprevalence observed at the end of the 1980s might be related to modifications in social behavior among newer drug users, partial exhaustion of the susceptible population, and increasing risk awareness in more experienced users. |
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Giuseppe D'Alessandro Department of Hygiene and Microbiology, School of Medicine, University of Palermo, Italy |
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0002-9262 |
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PMID:1626537 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
5258 |
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Mallavarapu, S.; Stoinski, T.S.; Bloomsmith, M.A.; Maple, T.L. |
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Title |
Postconflict behavior in captive western lowland gorillas (Gorilla gorilla gorilla) |
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Journal Article |
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Year |
2006 |
Publication |
American journal of primatology |
Abbreviated Journal |
Am. J. Primatol. |
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Volume |
68 |
Issue |
8 |
Pages |
789-801 |
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Keywords |
Animals; *Behavior, Animal; *Competitive Behavior; Conflict (Psychology); Female; Gorilla gorilla/*physiology/psychology; Male; Time Factors |
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Abstract |
Postconflict (PC) behaviors, including reconciliation and consolation, have been observed in many primate and several nonprimate species. Using the PC-matched control (MC) method, PC behavior was examined in two groups (n=13) of captive western lowland gorillas, a species for which no conflict resolution data have been published. Analyses of 223 conflicts showed significantly more affiliation between former opponents after a conflict when compared to control periods, indicating reconciliation. Results also showed significantly more affiliation between the victim and a third-party after a conflict, indicating consolation. Both solicited and unsolicited consolation were observed. The majority of the affiliative interactions observed for both reconciliation and consolation were social proximity, which suggests that unlike most nonhuman primates, proximity, rather than physical contact, may be the main mechanism for resolving conflicts in western lowland gorillas. PC behavior was not uniform throughout the groups, but rather varied according to dyad type. |
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Zoo Atlanta, Atlanta, Georgia 30315, USA. smallavarapu@zooatlanta.org |
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0275-2565 |
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PMID:16847973 |
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no |
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Call Number |
refbase @ user @ |
Serial |
2873 |
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Manson, J.H.; Perry, S.; Stahl, D. |
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Title |
Reconciliation in wild white-faced capuchins (Cebus capucinus) |
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Journal Article |
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Year |
2005 |
Publication |
American journal of primatology |
Abbreviated Journal |
Am. J. Primatol. |
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Volume |
65 |
Issue |
3 |
Pages |
205-219 |
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Keywords |
Aggression; Animals; Cebus/*psychology; Female; Male; Sex Factors; *Social Behavior; Social Dominance; Time Factors |
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Abstract |
The likelihood of reconciliation (defined as preferential peaceful contact among former opponents following conflicts) has been predicted to vary positively with relationship value and compatibility, and negatively with relationship security. Long-term data on wild white-faced capuchins (Cebus capucinus) indicate that dyads consisting of an adult female and an alpha male have high value and compatibility, but low security. Two studies of C. capucinus postconflict (PC) behavior were carried out at Lomas Barbudal Biological Reserve, Costa Rica. One study consisted of 30-min PC and matched control (MC) follows. The second study extracted PC and MC periods from long follows, yielding PC/MC periods averaging 105 min. In study 2, but not study 1, significantly more PC/MC pairs were attracted (former opponents affiliated with each other sooner in the PC period than in the MC period) than were dispersed (former opponents affiliated with each other sooner in the MC period than in the PC period). Reconciliation in study 2 could not be explained as a by-product of former opponents' tendency to seek affiliative contact with conspecifics generally, or of the spatial proximity of opponents following conflicts. Attempted reconciliation was less likely to be followed by renewed aggression when reconciliation attempts were delayed following conflicts. The data were insufficient for a formal test of differences in conciliatory tendency (the difference between the number of attracted and dispersed PC/MC pairs, divided by the total number of pairs) among dyad types to be conducted. |
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Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany. manson@eva.mpg.de |
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0275-2565 |
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PMID:15772989 |
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Call Number |
refbase @ user @ |
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2874 |
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Author |
Palagi, E.; Paoli, T.; Tarli, S.B. |
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Title |
Reconciliation and consolation in captive bonobos (Pan paniscus) |
Type |
Journal Article |
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Year |
2004 |
Publication |
American journal of primatology |
Abbreviated Journal |
Am. J. Primatol. |
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Volume |
62 |
Issue |
1 |
Pages |
15-30 |
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Keywords |
Aggression/psychology; *Agonistic Behavior; Animals; Animals, Zoo/*psychology; *Conflict (Psychology); *Empathy; Female; Male; Pan paniscus/*psychology; Sex Factors; *Social Behavior; Time Factors |
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Abstract |
Although reconciliation in bonobos (Pan paniscus) has previously been described, it has not been analyzed heretofore by the postconflict (PC) match-control (MC) method. Furthermore, although reconciliation has been investigated before in this species, consolation has not. In this study we analyzed agonistic and affiliative contacts in all sex-class combinations to clarify and reevaluate the occurrence of reconciliation in bonobos via the PC-MC method. We also investigated the occurrence of consolation by analyzing the victims' triadic contact tendency (TCT), the influence of the sex of victims, and the relative occurrence of consolation and reconciliation. We collected 167 pairs of PC-MC observations in a captive group of bonobos (in Apeldoorn, The Netherlands). The conciliatory tendency (CCT) we obtained was tendentially lower than the mean value previously found for Yerkes captive chimpanzees. Close relationships, which were present in all female-female (FF) and some male-female (MF) dyads, positively affected reconciliation rates. When only adult PC-MC pairs (157) were considered, the mean TCTs and CCTs did not differ significantly. When we focused on types of PC affiliative contact, in the case of consolation we found a striking preference for sociosexual patterns. As to the relative occurrence of consolation and reconciliation, the highest level of the former was found in the absence of the latter. When reconciliation took place, consolation generally preceded it, suggesting that consolation may be a substitutive behavior. Our findings suggest that even if reconciliation remains the best option, consolation may be an alternative substitute for reconciliation that is used to buffer the tension originating from an unresolved conflict. Reconciliation and consolation are complex phenomena that are probably related to the life history of a group. Given that few studies have been conducted on this subject, we can not at this time make any generalizations regarding conflict resolution in certain species by comparing results among studies. |
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Address |
Centro Interdipartimentale Museo di Storia Naturale e del Territorio, Universita di Pisa, Pisa, Italy. betta.palagi@museo.unipi.it |
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0275-2565 |
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PMID:14752810 |
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no |
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Call Number |
refbase @ user @ |
Serial |
2876 |
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Bottoms, G.D.; Roesel, O.F.; Rausch, F.D.; Akins, E.L. |
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Title |
Circadian variation in plasma cortisol and corticosterone in pigs and mares |
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Journal Article |
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Year |
1972 |
Publication |
American Journal of Veterinary Research |
Abbreviated Journal |
Am J Vet Res |
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33 |
Issue |
4 |
Pages |
785-790 |
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Keywords |
Animals; *Circadian Rhythm; Corticosterone/*blood; Female; Horses/*metabolism; Hydrocortisone/*blood; Methods; Swine/*metabolism; Time Factors |
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0002-9645 |
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PMID:5017871 |
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Equine Behaviour @ team @ |
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4074 |
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Lewis, K.P.; Jaffe, S.; Brannon, E.M. |
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Title |
Analog number representations in mongoose lemurs (Eulemur mongoz): evidence from a search task |
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Journal Article |
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Year |
2005 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
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Volume |
8 |
Issue |
4 |
Pages |
247-252 |
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Keywords |
Analysis of Variance; Animals; *Behavior, Animal; *Feeding Behavior; Female; Lemuridae/*psychology; Male; Mathematics; Odors; Smell/physiology; Time Factors |
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Abstract |
A wealth of data demonstrating that monkeys and apes represent number have been interpreted as suggesting that sensitivity to number emerged early in primate evolution, if not before. Here we examine the numerical capacities of the mongoose lemur (Eulemur mongoz), a member of the prosimian suborder of primates that split from the common ancestor of monkeys, apes and humans approximately 47-54 million years ago. Subjects observed as an experimenter sequentially placed grapes into an opaque bucket. On half of the trials the experimenter placed a subset of the grapes into a false bottom such that they were inaccessible to the lemur. The critical question was whether lemurs would spend more time searching the bucket when food should have remained in the bucket, compared to when they had retrieved all of the food. We found that the amount of time lemurs spent searching was indicative of whether grapes should have remained in the bucket, and furthermore that lemur search time reliably differentiated numerosities that differed by a 1:2 ratio, but not those that differed by a 2:3 or 3:4 ratio. Finally, two control conditions determined that lemurs represented the number of food items, and neither the odor of the grapes, nor the amount of grape (e.g., area) in the bucket. These results suggest that mongoose lemurs have numerical representations that are modulated by Weber's Law. |
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Department of Anthropology, Washington University, St. Louis, MO 63130-4899, USA |
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1435-9448 |
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PMID:15660208 |
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Equine Behaviour @ team @ |
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2497 |
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Author |
Beran, M.J. |
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Title |
Long-term retention of the differential values of Arabic numerals by chimpanzees (Pan troglodytes) |
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Journal Article |
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Year |
2004 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
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Volume |
7 |
Issue |
2 |
Pages |
86-92 |
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Keywords |
Animals; Cognition; Female; Language; Longitudinal Studies; Male; *Mathematics; *Mental Recall; Pan troglodytes/*psychology; *Retention (Psychology); *Semantics; Time Factors |
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Abstract |
As previously reported (Beran and Rumbaugh, 2001), two chimpanzees used a joystick to collect dots, one-at-a-time, on a computer monitor, and then ended a trial when the number of dots collected was equal to the Arabic numeral presented for the trial. Here, the chimpanzees were presented with the task again after an interval of 6 months and then again after an additional interval of 3.25 years. During each interval, the chimpanzees were not presented with the task, and this allowed an assessment of the extent to which both animals retained the values of each Arabic numeral. Despite lower performance at each retention interval compared to the original study, both chimpanzees performed above chance levels in collecting a quantity of dots equal to the target numeral, one chimpanzee for the numerals 1-7, and the second chimpanzee for the numerals 1-6. For the 3.25-year retention, errors were more dispersed around each target numeral than in the original study, but the chimpanzees' performances again appeared to be based on a continuous representation of magnitude rather than a discrete representation of number. These data provide an experimental demonstration of long-term retention of the differential values of Arabic numerals by chimpanzees. |
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Language Research Center, Georgia State University, 3401 Panthersville Road, Decatur, GA 30034, USA. mjberan@yahoo.com |
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1435-9448 |
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PMID:15069607 |
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Call Number |
Equine Behaviour @ team @ |
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2533 |
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Reichmuth Kastak, C.; Schusterman, R.J. |
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Title |
Long-term memory for concepts in a California sea lion ( Zalophus californianus) |
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Journal Article |
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Year |
2002 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
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Volume |
5 |
Issue |
4 |
Pages |
225-232 |
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Animals; Concept Formation; Female; Memory/*physiology; Mental Processes; Sea Lions/physiology/*psychology; Time Factors |
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Abstract |
An adult California sea lion ( Zalophus californianus) with extensive experience in performing discrimination learning tasks was tested to evaluate her long-term memory for two previously learned concepts. An associative concept, that of equivalence classification, was retested after a retention interval of approximately 1 year. The sea lion had originally shown emergent equivalence classification with nonsimilarity-based classes of stimuli in a simple discrimination repeated-reversal procedure as well as in a matching-to-sample procedure. The 1-year memory test revealed no decrement in classification performance in either procedure. A relational concept, that of generalized identity matching, was retested after approximately 10 years. The sea lion had originally received trial-and-error exemplar training with identity matching-to-sample problems prior to transferring the concept to novel stimulus configurations. In the 10-year memory test, the sea lion immediately and reliably applied the previously established identity concept to familiar and novel sets of matching problems. These are the first reports of long-term conceptual memory in a nonprimate species. The experimental findings are consistent with a variety of observations of sea lions in natural settings, which indicate that natal sites, feeding areas, and individuals may be remembered over long periods of time. |
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Long Marine Laboratory, University of California at Santa Cruz, 100 Shaffer Road, Santa Cruz, CA 95060, USA. coll@cats.ucsc.edu |
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1435-9448 |
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PMID:12461600 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2590 |
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Author |
Waite, T.A. |
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Title |
Interruptions improve choice performance in gray jays: prolonged information processing versus minimization of costly errors |
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Journal Article |
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Year |
2002 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
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Volume |
5 |
Issue |
4 |
Pages |
209-214 |
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Animals; *Behavior, Animal; *Choice Behavior; Female; Learning; Male; Models, Biological; Motivation; Reinforcement Schedule; Songbirds/*physiology; Time Factors |
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Abstract |
Under the assumption that selection favors minimization of costly errors, erroneous choice may be common when its fitness cost is low. According to an adaptive-choice model, this cost depends on the rate at which an animal encounters the choice: the higher this rate, the smaller the cost of choosing a less valuable option. Errors should thus be more common when interruptions to foraging are shorter. A previous experiment supported this prediction: gray jays, Perisoreus canadensis, were more error prone when subjected to shorter delays to access to food rewards. This pattern, though, is also predicted by an attentional-constraints model. Because the subjects were able to inspect the rewards during delays, their improved performance when subjected to longer delays could have been a byproduct of the experimentally prolonged opportunity for information processing. To evaluate this possibility, a follow-up experiment manipulated both delay to access and whether rewards could be inspected during delays. Depriving jays of the opportunity to inspect rewards (using opaque lids) induced only a small, nonsignificant increase in error rate. This effect was independent of length of delay and so the jays' improved performance when subjected to longer delays was not simply a byproduct of prolonged information processing. More definitively, even when the jays were prevented from inspecting rewards during delays, their performance improved when subjected to longer delays. The findings are thus consistent with the adaptive-choice model. |
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Department of Evolution, Ecology, and Organismal Biology, Ohio State University, 1735 Neil Avenue, Columbus, OH 43210-1293, USA. waite.1@osu.edu |
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Series Volume |
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Series Issue |
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Edition |
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ISSN |
1435-9448 |
ISBN |
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Medium |
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Area |
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Expedition |
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Conference |
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Notes |
PMID:12461598 |
Approved |
no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
2592 |
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| Permanent link to this record |
