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Author (up) Alexander, F.; Collett, R.A.
Title Pethidine in the horse Type Journal Article
Year 1974 Publication Research in veterinary science Abbreviated Journal Res Vet Sci
Volume 17 Issue 1 Pages 136-137
Keywords Animals; Half-Life; Horses/*metabolism; Injections, Intravenous/veterinary; Male; Meperidine/administration & dosage/analysis/*metabolism/pharmacology
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ISSN 0034-5288 ISBN Medium
Area Expedition Conference
Notes PMID:4421117 Approved no
Call Number refbase @ user @ Serial 113
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Author (up) Alexander, F.; Nicholson, J.D.
Title The blood and saliva clearances of phenobarbitone and pentobarbitone in the horse Type Journal Article
Year 1968 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol
Volume 17 Issue 2 Pages 203-210
Keywords Animals; Female; *Horses; Injections, Intravenous; Male; Metabolic Clearance Rate; Pentobarbital/blood/*metabolism; Phenobarbital/blood/*metabolism; Protein Binding; *Saliva; Time Factors
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Language English Summary Language Original Title
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ISSN 0006-2952 ISBN Medium
Area Expedition Conference
Notes PMID:5647047 Approved no
Call Number refbase @ user @ Serial 117
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Author (up) Bugnyar, T.; Kotrschal, K.
Title Leading a conspecific away from food in ravens ( Corvus corax)? Type Journal Article
Year 2004 Publication Animal Cognition Abbreviated Journal Anim. Cogn.
Volume 7 Issue 2 Pages 69-76
Keywords Misleading – Deception – Raven – Social foraging
Abstract Active misleading of conspecifics has been described as a social strategy mainly for primates. Here we report a raven leading a competitor away from food in a social foraging task. Four individuals had to search and compete for hidden food at color-marked clusters of artificial food caches. At the beginning of the experiment, a subordinate male found and exploited the majority of the food. As a result, the dominant male displaced him from the already opened boxes. The subordinate male then developed a pattern, when the loss of reward to the dominant got high, of moving to unrewarded clusters and opening boxes there. This diversion often led the dominant to approach those unrewarded clusters and the subordinate then had a head start for exploiting the rewarded boxes. Subsequently, however, the dominant male learned not to follow the subordinate to unrewarded clusters and eventually started searching for the reward himself. These interactions between the two males illustrate the ravens' potential for deceptively manipulating conspecifics. We discuss under which circumstances ravens might use this capacity.
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Notes Approved no
Call Number Serial 2080
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Author (up) Bugnyar, T.; Kotrschal, K.
Title Movement coordination and signalling in ravens (Corvus corax): an experimental field study Type Journal Article
Year 2001 Publication Acta ethologica Abbreviated Journal Acta. Ethol.
Volume 3 Issue 2 Pages 101-109
Keywords Ravens – Corvus corax – Foraging – Coordination – Communication
Abstract Vagrant non-breeding ravens frequently attract conspecifics to rich ephemeral food sources. There, grouping may allow them to overcome the defence of territorial breeders. Here, we focus on ravens making use of regular food supplies in a game park, where they divert food from the provision of park animals. We investigated if ravens foraging in the Cumberland game park (Grünau, Austria) are attentive towards one another when they experience some unpredictability in food provisioning. We confronted a group of 30-50 ravens with two different treatments. Ten minutes ahead of the feeding of either wolves or wild boars we showed buckets containing pieces of meat to the ravens flying overhead. In the reliable cue treatment (RCT), the meat was placed next to one of the two enclosures, whereas in the unreliable cue treatment (UCT), the buckets were placed simultaneously in front of both enclosures though only in one of the enclosures were the animals fed 10 min later. Thus, during RCT but not during UCT, ravens could predict where food would become available. Only during UCT, ravens moved in large groups between the two feeding sites. Many ravens moving at the same time in the same direction may indicate some co-ordination in space and time, which is most likely achieved by social attraction among individuals. Furthermore, the number of ravens approaching and leaving, respectively, a feeding site cross-correlated with a temporary increase in the rate of a food-associated call, the yell. This suggests that in addition to watching each other, calling may have contributed to group formation. Possible benefits of group formation during food inspection are discussed.
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Notes Approved no
Call Number Serial 2081
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Author (up) Carroll, G.L.; Matthews, N.S.; Hartsfield, S.M.; Slater, M.R.; Champney, T.H.; Erickson, S.W.
Title The effect of detomidine and its antagonism with tolazoline on stress-related hormones, metabolites, physiologic responses, and behavior in awake ponies Type Journal Article
Year 1997 Publication Veterinary surgery : VS : the official journal of the American College of Veterinary Surgeons Abbreviated Journal Vet Surg
Volume 26 Issue 1 Pages 69-77
Keywords Adrenergic alpha-Antagonists/administration & dosage/*pharmacology; Animals; Behavior, Animal/drug effects/physiology; Blood Glucose/metabolism; Blood Pressure/drug effects/physiology; Consciousness/physiology; Dose-Response Relationship, Drug; Drug Interactions; Epinephrine/blood; Fatty Acids, Nonesterified/blood; Female; Heart Rate/drug effects/physiology; Horse Diseases/metabolism/physiopathology/psychology; Horses/blood/metabolism/*physiology; Hydrocortisone/blood; Hypnotics and Sedatives/administration & dosage/*pharmacology; Imidazoles/administration & dosage/*pharmacology; Injections, Intravenous; Male; Norepinephrine/blood; Receptors, Adrenergic, alpha/drug effects/*physiology; Stress/metabolism/physiopathology/veterinary; Time Factors; Tolazoline/administration & dosage/*pharmacology
Abstract Six ponies were used to investigate the effect of tolazoline antagonism of detomidine on physiological responses, behavior, epinephrine, norepinephrine, cortisol, glucose, and free fatty acids in awake ponies. Each pony had a catheter inserted into a jugular vein 1 hour before beginning the study. Awake ponies were administered detomidine (0.04 mg/kg intravenously [i.v.]) followed 20 minutes later by either tolazoline (4.0 mg/kg i.v.) or saline. Blood samples were drawn from the catheter 5 minutes before detomidine administration (baseline), 5 minutes after detomidine administration, 20 minutes before detomidine administration which was immediately before the administration of tolazoline or saline (time [T] = 0), and at 5, 30, and 60 minutes after injections of tolazoline or saline (T = 5, 30, and 60 minutes, respectively). Compared with heart rate at T = 0, tolazoline antagonism increased heart rate 45% at 5 minutes. There was no difference in heart rate between treatments at 30 minutes. Blood pressure remained stable after tolazoline, while it decreased over time after saline. Compared with concentrations at T = 0, tolazoline antagonism of detomidine in awake ponies resulted in a 55% increase in cortisol at 30 minutes and a 52% increase in glucose at 5 minutes. The change in free fatty acids was different for tolazoline and saline over time. Free fatty acids decreased after detomidine administration. Free fatty acids did not change after saline administration. After tolazoline administration, free fatty acids increased transiently. Tolazoline tended to decrease sedation and analgesia at 15 and 60 minutes postantagonism. Antagonism of detomidine-induced physiological and behavioral effects with tolazoline in awake ponies that were not experiencing pain appears to precipitate a stress response as measured by cortisol, glucose, and free fatty acids. If antagonism of an alpha-agonist is contemplated, the potential effect on hormones and metabolites should be considered.
Address Department of Small Animal Medicine and Surgery, Texas A&M University, College Station, USA
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ISSN 0161-3499 ISBN Medium
Area Expedition Conference
Notes PMID:9123816 Approved no
Call Number refbase @ user @ Serial 96
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Author (up) Doherty, T.J.; Frazier, D.L.
Title Effect of intravenous lidocaine on halothane minimum alveolar concentration in ponies Type Journal Article
Year 1998 Publication Equine veterinary journal Abbreviated Journal Equine Vet J
Volume 30 Issue 4 Pages 300-303
Keywords Anesthetics/administration & dosage/blood/*pharmacology; Anesthetics, Inhalation/administration & dosage/*analysis; Animals; Consciousness/drug effects; Dose-Response Relationship, Drug; Halothane/administration & dosage/*analysis; Horses/*physiology; Infusions, Intravenous/veterinary; Lidocaine/administration & dosage/blood/*pharmacology; Male
Abstract This study investigated the effect of lidocaine i.v. on halothane minimum alveolar concentration (MAC) in ponies. Six ponies were anaesthetised with thiopentone and succinylcholine, intubated and anaesthesia maintained with halothane. Ventilation was controlled and blood pressure maintained within clinically acceptable limits. Following a 2 h equilibration period, baseline halothane MAC was determined. The ponies were then given a loading dose of lidocaine (2.5 or 5 mg/kg bwt) or saline over 5 min, followed by a constant infusion of lidocaine (50 or 100 microg/kg/min, or saline, respectively). The halothane MAC was redetermined after a 60 min infusion of lidocaine or saline. The baseline halothane MAC for the control group was mean +/- s.d. 0.94 +/- 0.03%, and no significant decrease occurred following saline infusion. Lidocaine decreased halothane MAC in a dose-dependent fashion (r = 0.86; P < 0.0003). The results indicate that i.v. lidocaine may have a role in equine anaesthesia.
Address Department of Large Animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, Knoxville 37901-1071, USA
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Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:9705112 Approved no
Call Number refbase @ user @ Serial 95
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Author (up) Grubb, T.L.; Foreman, J.H.; Benson, G.J.; Thurmon, J.C.; Tranquilli, W.J.; Constable, P.D.; Olson, W.O.; Davis, L.E.
Title Hemodynamic effects of calcium gluconate administered to conscious horses Type Journal Article
Year 1996 Publication Journal of veterinary internal medicine / American College of Veterinary Internal Medicine Abbreviated Journal J Vet Intern Med
Volume 10 Issue 6 Pages 401-404
Keywords Animals; Blood Pressure/drug effects/physiology; Calcium/blood; Calcium Gluconate/administration & dosage/*pharmacology; Cardiac Output/drug effects/physiology; Consciousness/*physiology; Dose-Response Relationship, Drug; Female; Heart Rate/drug effects/physiology; Hemodynamic Processes/*drug effects/physiology; Horses/blood/*physiology; Infusions, Intravenous; Male; Myocardial Contraction/drug effects/physiology; Respiration/drug effects/physiology; Stroke Volume/drug effects/physiology; Time Factors
Abstract Calcium gluconate was administered to conscious horses at 3 different rates (0.1, 0.2, and 0.4 mg/kg/min for 15 minutes each). Serum calcium concentrations and parameters of cardiovascular function were evaluated. All 3 calcium administration rates caused marked increases in both ionized and total calcium concentrations, cardiac index, stroke index, and cardiac contractility (dP/dtmax). Mean arterial pressure and right atrial pressure were unchanged; heart rate decreased markedly during calcium administration. Ionized calcium concentration remained between 54% and 57% of total calcium concentration throughout the study. We conclude that calcium gluconate can safely be administered to conscious horses at 0.1 to 0.4 mg/kg/min and that administration will result in improved cardiac function.
Address Department of Veterinary Clinical Medicine, University of Illinois at Urbana-Champaign, USA
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ISSN 0891-6640 ISBN Medium
Area Expedition Conference
Notes PMID:8947873 Approved no
Call Number refbase @ user @ Serial 97
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Author (up) Hubbell, J.A.E.; Muir, W.W.
Title Antagonism of detomidine sedation in the horse using intravenous tolazoline or atipamezole Type Journal Article
Year 2006 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 38 Issue 3 Pages 238-241
Keywords Animals; Behavior, Animal/drug effects/physiology; Dose-Response Relationship, Drug; Double-Blind Method; Horses/*physiology; Hypnotics and Sedatives/*antagonists & inhibitors; Imidazoles/*antagonists & inhibitors/*pharmacology; Infusions, Intravenous/veterinary; Kinetics; Safety; Tolazoline/*pharmacology; Videotape Recording
Abstract REASONS FOR PERFORMING STUDY: The ability to shorten the duration of sedation would potentially improve safety and utility of detomidine. OBJECTIVES: To determine the effects of tolazoline and atipamezole after detomidine sedation. HYPOTHESIS: Administration of tolazoline or atipamezole would not affect detomidine sedation. METHODS: In a randomised, placebo-controlled, double-blind, descriptive study, detomidine (0.02 mg/kg bwt i.v.) was administered to 6 mature horses on 4 separate occasions. Twenty-five mins later, each horse received one of 4 treatments: Group 1 saline (0.9% i.v.) as a placebo control; Group 2 atipamezole (0.05 mg/kg bwt i.v.); Group 3 atipamezole (0.1 mg/kg bwt i.v.); and Group 4 tolazoline (4.0 mg/kg bwt i.v.). Sedation, muscle relaxation and ataxia were scored by 3 independent observers at 9 time points. Horses were led through an obstacle course at 7 time points. Course completion time was recorded and the ability of the horse to traverse the course was scored by 3 independent observers. Horses were videotaped before, during and after each trip through the obstacle course. RESULTS: Atipamezole and tolazoline administration incompletely antagonised the effects of detomidine, but the time course to recovery was shortened. CONCLUSIONS AND POTENTIAL RELEVANCE: Single bolus administration of atipamezole or tolazoline produced partial reversal of detomidine sedation and may be useful for minimising detomidine sedation.
Address Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, 601 Tharp Street, Columbus, Ohio 43210, USA
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Series Editor Series Title Abbreviated Series Title
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ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:16706278 Approved no
Call Number Serial 1869
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Author (up) Romano, N.; Vitale, F.; Alesi, D.R.; Bonura, F.; La Licata, R.; Intonazzo, V.; Dardanoni, G.; Mammina, C.
Title The changing pattern of human immunodeficiency virus type 1 infection in intravenous drug users. Results of a six-year seroprevalence study in Palermo, Italy Type Journal Article
Year 1992 Publication American Journal of Epidemiology Abbreviated Journal Am J Epidemiol
Volume 135 Issue 11 Pages 1189-1196
Keywords Acquired Immunodeficiency Syndrome/*epidemiology; Adolescent; Adult; Chi-Square Distribution; Cross-Sectional Studies; Female; HIV Antibodies/blood; HIV Infections/*epidemiology; HIV Seroprevalence/*trends; *Hiv-1; Hepatitis B Antibodies/blood; Hepatitis B Surface Antigens/blood; Heroin; Humans; Incidence; Italy/epidemiology; Logistic Models; Male; Multivariate Analysis; Odds Ratio; Prevalence; Risk Factors; Substance Abuse, Intravenous/*epidemiology; Time Factors
Abstract A cross-sectional seroepidemiologic study was carried out between 1985 and 1990 in 1,567 heterosexual intravenous drug users who had been seen at the AIDS Regional Reference Center in Palermo, Italy, to evaluate the rate of human immunodeficiency virus type 1 (HIV-1) seroprevalence in this group and its long-term trend. Sixty serum samples collected from drug users in 1980 and 1983, before the founding of the Center (1985), were tested as well. Some demographic and behavioral risk factors were studied in a subgroup of intravenous drug users enrolled in 1985, 1987, and 1990 for their possible association with HIV-1. These factors were also studied in relation to hepatitis B virus infection, since both viruses share the same modes of spread. These drug users had a higher prevalence of markers for hepatitis B virus than of HIV-1 antibodies, and the prevalence rates in sera collected declined over time for both infections. The presence of both antibodies to HIV-1 and markers for hepatitis B virus was independently associated with the age of the drug user, the duration of drug use, and the year of serum collection. Antibodies to HIV-1 were observed more frequently in females than in males. No relation was found between education or employment status and the presence of HIV-1 antibodies or hepatitis B virus markers. Although new HIV-1 infections still occur, the decline in seroprevalence observed at the end of the 1980s might be related to modifications in social behavior among newer drug users, partial exhaustion of the susceptible population, and increasing risk awareness in more experienced users.
Address Giuseppe D'Alessandro Department of Hygiene and Microbiology, School of Medicine, University of Palermo, Italy
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ISSN 0002-9262 ISBN Medium
Area Expedition Conference
Notes PMID:1626537 Approved no
Call Number Equine Behaviour @ team @ Serial 5258
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Author (up) Schloegl, C.; Kotrschal, K.; Bugnyar, T.
Title Modifying the object-choice task: Is the way you look important for ravens? Type Journal Article
Year 2008 Publication Behavioural Processes Abbreviated Journal Behav. Process.
Volume 77 Issue 1 Pages 61-65
Keywords Gaze; Modification; Object-choice task; Raven
Abstract Most animals seem to have difficulties in using gaze cues to find hidden food in object-choice tasks. For instance, chimpanzees usually fail in these tests, even though they are capable of following other's gaze geometrically behind barriers. Similar to chimpanzees, common ravens are skilled in tracking other's gaze but fail in object-choice tasks. We here explored whether procedural modifications, which had been used successfully in chimpanzees, would also yield positive results in ravens. In our modifications (a) the experimenter approached the cup while gazing at it, (b) the gaze cue was accompanied by a sound and (c) the experimenter could actually see the food while giving the gaze cue. Two out of seven birds performed above chance level in some of these conditions. However, we ascribe this improvement to the individuals' learning ability rather than to an understanding of the communicative nature of the task. This interpretation is further supported by results of a follow-up experiment suggesting that ravens may not rely on conspecifics' gaze cues for finding food caches in a natural foraging context. In sum, our results suggest that ravens may not transfer their gaze follow abilities to foraging situations involving hidden food.
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Notes Approved no
Call Number Equine Behaviour @ team @ Serial 4505
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