| Records |
| Author |
Bannasch, D.; Rinaldo, C.; Millon, L.; Latson, K.; Spangler, T.; Hubberty, S.; Galuppo, L.; Lowenstine, L. |
| Title |
SRY negative 64,XX intersex phenotype in an American saddlebred horse |
Type |
Journal Article |
| Year |
2007 |
Publication |
Veterinary Journal (London, England : 1997) |
Abbreviated Journal |
Vet J |
| Volume |
173 |
Issue |
2 |
Pages |
437-439 |
| Keywords |
Animals; Female; Genitalia/abnormalities; Hermaphroditism/*veterinary; Horse Diseases/*diagnosis/genetics; Horses/*genetics/*physiology; Karyotyping; Phenotype; Sex Differentiation; Sex Differentiation Disorders/diagnosis/veterinary; Sex-Determining Region Y Protein/genetics/*metabolism |
| Abstract |
A female American saddlebred horse was presented for surgical correction of a possible pseudohermaphrodite condition. The horse had abnormal external genitalia and exhibited stallion-like behaviour. No evidence of uterine or ovarian tissue was identified on laparoscopic examination, but hypoplastic testicular-like tissue was removed, although this was found to contain no spermatogonia upon histopathological examination. A karyotype was performed and showed the normal chromosomal complement for a female horse (64,XX). Polymerase chain reaction to detect the SRY gene was negative in peripheral blood as well as the testicular-like tissue. This case represents the first report of an SRY negative XX-male sex reversal intersex phenotype, which is a potentially inherited condition, in an American saddlebred horse. |
| Address |
Department of Population Health and Reproduction, School of Veterinary Medicine, University of California, Davis, CA 95616, USA. dlbannasch@ucdavis.edu |
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Place of Publication |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1090-0233 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:16386440 |
Approved |
no |
| Call Number |
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Serial |
1882 |
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| Author |
Hare, J.F.; Sealy, S.G.; Underwood, T.J.; Ellison, K.S.; Stewart, R.L.M. |
| Title |
Evidence of self-referent phenotype matching revisited: airing out the armpit effect |
Type |
Journal Article |
| Year |
2003 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
6 |
Issue |
1 |
Pages |
65-68 |
| Keywords |
Alleles; Animals; Birds; Cricetinae; Dogs; Humans; Invertebrates; Learning; *Odors; Pedigree; Phenotype; *Recognition (Psychology); Self Psychology; *Social Behavior |
| Abstract |
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| Address |
Department of Zoology, University of Manitoba, Winnipeg, MB R3T 2N2, Canada. harejf@cc.umanitoba.ca |
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Thesis |
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Place of Publication |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1435-9448 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:12701614 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2576 |
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| Author |
Harman, F.S.; Nicol, C.J.; Marin, H.E.; Ward, J.M.; Gonzalez, F.J.; Peters, J.M. |
| Title |
Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis |
Type |
Journal Article |
| Year |
2004 |
Publication |
Nature medicine |
Abbreviated Journal |
Nat Med |
| Volume |
10 |
Issue |
5 |
Pages |
481-483 |
| Keywords |
Animals; Azoxymethane/toxicity; Colonic Neoplasms/etiology/genetics/*prevention & control; Colonic Polyps/etiology/genetics/pathology/prevention & control; Disease Models, Animal; Mice; Mice, Knockout; Mice, Mutant Strains; Phenotype; Receptors, Cytoplasmic and Nuclear/deficiency/genetics/*physiology; Transcription Factors/deficiency/genetics/*physiology |
| Abstract |
Peroxisome proliferator-activated receptor-delta (PPAR-delta; also known as PPAR-beta) is expressed at high levels in colon tumors, but its contribution to colon cancer is unclear. We examined the role of PPAR-delta in colon carcinogenesis using PPAR-delta-deficient (Ppard(-/-)) mice. In both the Min mutant and chemically induced mouse models, colon polyp formation was significantly greater in mice nullizygous for PPAR-delta. In contrast to previous reports suggesting that activation of PPAR-delta potentiates colon polyp formation, here we show that PPAR-delta attenuates colon carcinogenesis. |
| Address |
Department of Veterinary Science and The Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, Pennsylvania 16802, USA. jmp21@psu.edu |
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Place of Publication |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
1078-8956 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:15048110 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
77 |
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| Author |
Hauber, M.E.; Sherman, P.W. |
| Title |
Designing and interpreting experimental tests of self-referent phenotype matching |
Type |
Journal Article |
| Year |
2003 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
6 |
Issue |
1 |
Pages |
69-71 |
| Keywords |
Animals; Birds; Body Constitution; Color; Humans; Pedigree; *Perception; Phenotype; *Recognition (Psychology); Research Design; *Self Psychology |
| Abstract |
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| Address |
Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853-2702, USA |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1435-9448 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:12658536 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2580 |
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| Author |
Mateo, J.M.; Johnston, R.E. |
| Title |
Kin recognition by self-referent phenotype matching: weighing the evidence |
Type |
Journal Article |
| Year |
2003 |
Publication |
Animal Cognition |
Abbreviated Journal |
Anim. Cogn. |
| Volume |
6 |
Issue |
1 |
Pages |
73-76 |
| Keywords |
Animals; Brain/embryology; Cricetinae/embryology; Humans; Learning; Odors; Phenotype; *Recognition (Psychology); Reproducibility of Results; Research Design; *Self Psychology; *Smell |
| Abstract |
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| Address |
Department of Psychology, Cornell University, NY 14853-7601, Ithaca, USA. jmateo@uchicago.edu |
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Place of Publication |
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| Language |
English |
Summary Language |
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Original Title |
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| Series Editor |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
1435-9448 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:12658537 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
2579 |
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| Author |
McBride, S.D.; Parker, M.O.; Roberts, K.; Hemmings, A. |
| Title |
Applied neurophysiology of the horse; implications for training, husbandry and welfare |
Type |
Journal Article |
| Year |
2017 |
Publication |
Applied Animal Behaviour Science |
Abbreviated Journal |
Appl. Anim. Behav. Sci. |
| Volume |
190 |
Issue |
|
Pages |
90-101 |
| Keywords |
Horse; Neurophysiology; Behaviour; Endophenotype; Equitation science; Welfare |
| Abstract |
Understanding the neural circuits underlying equine behaviour has the potential to help optimise strategies of husbandry and training. This review discusses two areas of neurophysiological research in a range of species and relates this information to the horse. The first discussion focuses on mechanisms of learning and motivation and assesses how this information can be applied to improve the training of the horse. The second concerns the identification of the equine neurophysiological phenotype, through behavioural and genetic probes, as a way of improving strategies for optimal equine husbandry and training success. The review finishes by identifying directions for future research with an emphasis on how neurophysiological systems (and thus behaviour) can be modified through strategic husbandry. This review highlights how a neurophysioloigical understanding of horse behaviour can play an important role in attaining the primary objectives of equitation science as well as improving the welfare of the horse. |
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Thesis |
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Place of Publication |
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Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0168-1591 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
6627 |
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| Author |
McComb, K.; Clutton-Brock, T. |
| Title |
Is mate choice copying or aggregation responsible for skewed distributions of females on leks? |
Type |
Journal Article |
| Year |
1994 |
Publication |
Proceedings. Biological sciences / The Royal Society |
Abbreviated Journal |
Proc Biol Sci |
| Volume |
255 |
Issue |
1342 |
Pages |
13-19 |
| Keywords |
Animals; Deer/*physiology; Estrus/physiology; Female; Male; Phenotype; Sexual Behavior, Animal/*physiology; Territoriality |
| Abstract |
In several lek-breeding populations of birds and mammals, females arriving on leks tend to join males that already have females in their territories. This might occur either because females have an evolved preference for mating with males that are attractive to other females, or because they join groups of other females to obtain greater safety from predation or dangerous harassment by males. We have previously used controlled experiments to show that oestrous fallow deer females join males with established harems because they are attracted to female groups rather than to the males themselves. Here we demonstrate that the preference for males with females over males without females is specific to oestrous females and weak or absent in anoestrous ones, and that it is not associated with a preference for mating with males that have previously been seen to mate with other females. Furthermore, oestrous females given the choice between males that do not already have females with them show no significant preference for antlered over deantlered males or for older males over younger ones. We conclude that female attraction to other females on the lek is likely to be an adaptation to avoiding harassment in mixed-sex herds. In this situation, a male's ability to maintain the cohesion of his harem may be the principal cause of variation in mating success between males. |
| Address |
Department of Zoology, University of Cambridge, U.K |
| Corporate Author |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0962-8452 |
ISBN |
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Medium |
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| Area |
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Expedition |
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Conference |
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| Notes |
PMID:8153135 |
Approved |
no |
| Call Number |
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Serial |
1823 |
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| Author |
Moon, C.; Baldridge, M.T.; Wallace, M.A.; Burnham, C.-A.D.; Virgin, H.W.; Stappenbeck, T.S. |
| Title |
Vertically transmitted faecal IgA levels determine extra-chromosomal phenotypic variation |
Type |
Journal Article |
| Year |
2015 |
Publication |
Nature |
Abbreviated Journal |
Nature |
| Volume |
521 |
Issue |
7550 |
Pages |
90-93 |
| Keywords |
Phenotype |
| Abstract |
The proliferation of genetically modified mouse models has exposed phenotypic variation between investigators and institutions that has been challenging to control1-5. In many cases, the microbiota is the presumed culprit of the variation. Current solutions to account for phenotypic variability include littermate and maternal controls or defined microbial consortia in gnotobiotic mice6,7. In conventionally raised mice, the microbiome is transmitted from the dam2,8,9. Here we show that microbially–driven dichotomous fecal IgA levels in WT mice within the same facility mimic the effects of chromosomal mutations. We observed in multiple facilities that vertically-transmissible bacteria in IgA-Low mice dominantly lowered fecal IgA levels in IgA-High mice after cohousing or fecal transplantation. In response to injury, IgA-Low mice showed increased damage that was transferable by fecal transplantation and driven by fecal IgA differences. We found that bacteria from IgA-Low mice degraded the secretory component (SC) of SIgA as well as IgA itself. These data indicate that phenotypic comparisons between mice must take into account the non-chromosomal hereditary variation between different breeders. We propose fecal IgA as one marker of microbial variability and conclude that cohousing and/or fecal transplantation enables analysis of progeny from different dams. |
| Address |
Department of Pathology and Immunology, Washington University School of Medicine, St Louis, Missouri 63110, USA. |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
eng |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0028-0836 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
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Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
6005 |
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| Author |
Morley, K.I.; Montgomery, G.W. |
| Title |
The genetics of cognitive processes: candidate genes in humans and animals |
Type |
Journal Article |
| Year |
2001 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
| Volume |
31 |
Issue |
6 |
Pages |
511-531 |
| Keywords |
Animals; *Chromosome Mapping; Drosophila melanogaster; Genetic Markers/*genetics; Humans; Intelligence/*genetics; Mental Retardation/genetics; Mice; Phenotype; Quantitative Trait, Heritable |
| Abstract |
It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition was compiled. Some genes are particularly strong candidates based on evidence for involvement in cognitive processes in humans, mice, and Drosophila melanogaster. This survey confirms that many genes are associated with cognitive variation and highlights the potential importance of animal models in the study of human cognition. |
| Address |
Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Brisbane, Australia |
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Thesis |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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Series Issue |
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Edition |
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| ISSN |
0001-8244 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:11838530 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4141 |
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| Author |
Zhang, T.-Y.; Parent, C.; Weaver, I.; Meaney, M.J. |
| Title |
Maternal programming of individual differences in defensive responses in the rat |
Type |
Journal Article |
| Year |
2004 |
Publication |
Annals of the New York Academy of Sciences |
Abbreviated Journal |
Ann N Y Acad Sci |
| Volume |
1032 |
Issue |
|
Pages |
85-103 |
| Keywords |
Adaptation, Biological; Aggression/*physiology; Animals; Evolution; Female; Gene Expression/physiology; Humans; Individuality; *Maternal Behavior; Phenotype; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Stress, Psychological/physiopathology |
| Abstract |
This paper describes the results of a series of studies showing that variations in mother-pup interactions program the development of individual differences in behavioral and endocrine stress responses in the rat. These effects are associated with altered expression of genes in brain regions, such as the amygdala, hippocampus, and hypothalamus, that regulate the expression of stress responses. Studies from evolutionary biology suggest that such “maternal effects” are common and often associated with variations in the quality of the maternal environment. Together these findings suggest an epigenetic process whereby the experience of the mother alters the nature of the parent-offspring interactions and thus the phenotype of the offspring. |
| Address |
McGill Program for the Study of Behavior, Genes and Environment, Douglas Hospital Research Centre, Department of Psychiatry, McGill University, 6875 boul. LaSalle, Montreal (Quebec), Canada H4H 1R3 |
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Place of Publication |
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Editor |
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| Language |
English |
Summary Language |
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Original Title |
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Series Title |
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Abbreviated Series Title |
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| Series Volume |
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Series Issue |
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Edition |
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| ISSN |
0077-8923 |
ISBN |
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Medium |
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Expedition |
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Conference |
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| Notes |
PMID:15677397 |
Approved |
no |
| Call Number |
Equine Behaviour @ team @ |
Serial |
4132 |
| Permanent link to this record |
