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Author Hillidge, C.J.; Lees, P. openurl 
  Title Cardiac output in the conscious and anaesthetised horse Type Journal Article
  Year 1975 Publication Equine veterinary journal Abbreviated Journal Equine Vet J  
  Volume 7 Issue 1 Pages 16-21  
  Keywords Anesthesia, Inhalation/*veterinary; Animals; Carbon Dioxide/blood; *Cardiac Output/veterinary; *Consciousness; Electrocardiography/veterinary; Ether, Ethyl; Female; Halothane; Heart Rate; Heart Ventricles/physiology; Horses/*physiology; Hydrogen-Ion Concentration; Male; Oxygen/blood; Posture  
  Abstract Cardiac output in the horse was measured before and at predetermined times during 2-hour periods of thiopentone-halothane and thiopentone-diethyl ether anaesthesia. Left ventricular stroke volume was decreased to a similar extent during anaesthesia with each volatile agent, but a greater reduction in cardiac output occurred during halothane anaesthesia. This finding reflected the differing effects of halothane and ether on heart rate, a slight bradycardia occurring with the former agent while ether produced a small degree of tachycardia. The latter effect was attributed to enhanced sympathoadrenal activity. Changes in cardiac output and stroke volume were considered in relation to other factors, including arterial blood pH and tensions of oxygen and carbon dioxide. Positive correlations between some of these variables and cardiac function were established. With both volatile agents the reductions in stroke volume and cardiac output were related to the duration of anaesthesia, being greatest during the early stages. Possible reasons for the tendency of stroke volume and cardiac output to return towards control levels are discussed.  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:234842 Approved no  
  Call Number refbase @ user @ Serial 102  
Permanent link to this record
 

 
Author Lees, P.; Tavernor, W.D. openurl 
  Title Influence of halothane and catecholamines on heart rate and rhythm in the horse Type Journal Article
  Year 1970 Publication British journal of pharmacology Abbreviated Journal Br J Pharmacol  
  Volume 39 Issue 1 Pages 149-159  
  Keywords Anesthesia, Inhalation; Animals; Arrhythmia/*chemically induced; Atropine/pharmacology; Catecholamines/*pharmacology; Consciousness; Epinephrine/administration & dosage; Ethers; Female; Halothane/*pharmacology; Heart Rate/*drug effects; Horses; Hypercapnia/physiopathology; Isoproterenol/pharmacology; Male; Norepinephrine/pharmacology; Propranolol/pharmacology  
  Abstract  
  Address  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0007-1188 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:5420092 Approved no  
  Call Number refbase @ user @ Serial 103  
Permanent link to this record
 

 
Author Alexander, F. openurl 
  Title Effect of phenylbutazone on electrolyte metabolism in ponies Type Journal Article
  Year 1982 Publication The Veterinary record Abbreviated Journal Vet. Rec.  
  Volume 110 Issue 12 Pages 271-272  
  Keywords Animals; Chlorides/metabolism; Electrolytes/*metabolism; Horses/*metabolism; Male; Phenylbutazone/*pharmacology; Sodium/metabolism  
  Abstract Phenylbutazone administered in therapeutic doses to ponies decreased urinary sodium and chloride excretion. The volume and osmolality of the urine was unaffected as was potassium excretion. Faecal excretion of chloride decreased and that of potassium increased, while faecal sodium excretion was unaffected. Plasma pH, bicarbonate and total carbon dioxide decreased after phenylbutazone administration. Packed cell volume, plasma sodium, potassium, carbon dioxide tension and chloride were unchanged.  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 0042-4900 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:7080416 Approved no  
  Call Number refbase @ user @ Serial 109  
Permanent link to this record
 

 
Author Alexander, F. openurl 
  Title The effect of some anti-diarrhoeal drugs on intestinal transit and faecal excretion of water and electrolytes in the horse Type Journal Article
  Year 1978 Publication Equine veterinary journal Abbreviated Journal Equine Vet J  
  Volume 10 Issue 4 Pages 229-234  
  Keywords Animals; Antidiarrheals/*pharmacology; Atropine/pharmacology; Electrolytes/*analysis/urine; Feces/*analysis; Gastrointestinal Motility/*drug effects; Horses/*metabolism/physiology; Loperamide/pharmacology; Male; Meperidine/pharmacology; Morphine/pharmacology; Opium/pharmacology; Water/*analysis  
  Abstract The effect of morphine, Tinct. opii, loperamide, pethidine and atropine on intestinal transit and the faecal and urinary excretion of water and electrolytes was studied in ponies. The rate of passage of a particulate marker was slowed by morphine, hastened then slowed by loperamide and Tinct. opii, and hastened by atropine. The liquid marker was slowed by Tinct. opii and hastened then slowed by the other drugs. Only loperamide decreased the faecal sodium excretion. This drug also decreased faecal water and weight; it appeared worthy of clinical trial in diarrhoea. Tinct. opii decreased by morphine, pethidine and atropine increased faecal water.  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 0425-1644 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:738263 Approved no  
  Call Number refbase @ user @ Serial 110  
Permanent link to this record
 

 
Author Alexander, F. openurl 
  Title The effect of diuretics on the faecal excretion of water and electrolytes in horses Type Journal Article
  Year 1977 Publication British journal of pharmacology Abbreviated Journal Br J Pharmacol  
  Volume 60 Issue 4 Pages 589-593  
  Keywords Animals; Body Water/*metabolism; Chlorides/metabolism; Electrolytes/*metabolism; Feces/*analysis; Furosemide/*pharmacology; Horses; Hydrochlorothiazide/*pharmacology; Male; Potassium/metabolism; Sodium/metabolism; Time Factors  
  Abstract 1. The effect on plasma, urinary and faecal electrolytes of frusemide and hydrochlorthiazide was measured in ponies, mean weight 180 kg. 2. The rapid loss in urine of large quantities of sodium had only a small effect on plasma sodium concentration. 3. Faecal sodium excretion was increased substantially after the administration of frusemide. 4. Frusemide increased faecal potassium during the 48 h following administration and faecal water in the 24/48 h period. It also produced a hypopotassaemia. 5. Hydrochlorthiazide increased faecal chloride during the 24 h after administration. 6. Frusemide increased the intestinal transit time of both liquid (polyethylene glycol) and particulate (Cr2O3) markers.  
  Address  
  Corporate Author Thesis  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0007-1188 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:907872 Approved no  
  Call Number refbase @ user @ Serial 111  
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Author Alexander, F.; Collett, R.A. openurl 
  Title Pethidine in the horse Type Journal Article
  Year 1974 Publication Research in veterinary science Abbreviated Journal Res Vet Sci  
  Volume 17 Issue 1 Pages 136-137  
  Keywords Animals; Half-Life; Horses/*metabolism; Injections, Intravenous/veterinary; Male; Meperidine/administration & dosage/analysis/*metabolism/pharmacology  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0034-5288 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:4421117 Approved no  
  Call Number refbase @ user @ Serial 113  
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Author Alexander, F.; Nicholson, J.D. openurl 
  Title The blood and saliva clearances of phenobarbitone and pentobarbitone in the horse Type Journal Article
  Year 1968 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol  
  Volume 17 Issue 2 Pages 203-210  
  Keywords Animals; Female; *Horses; Injections, Intravenous; Male; Metabolic Clearance Rate; Pentobarbital/blood/*metabolism; Phenobarbital/blood/*metabolism; Protein Binding; *Saliva; Time Factors  
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  Language English Summary Language Original Title  
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  Series Volume Series Issue Edition  
  ISSN 0006-2952 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:5647047 Approved no  
  Call Number refbase @ user @ Serial 117  
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Author Alexander, F.; Horner, M.W.; Moss, M.S. openurl 
  Title The salivary secretion and clearance in the horse of chloral hydrate and its metabolites Type Journal Article
  Year 1967 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol  
  Volume 16 Issue 7 Pages 1305-1311  
  Keywords Animals; Chloral Hydrate/blood/*metabolism/urine; Chromatography, Gas; Ethanol/blood/urine; Horses; Male; Parotid Gland/metabolism; Saliva/*analysis; Trichloroacetic Acid/blood/urine  
  Abstract  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0006-2952 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:6053598 Approved no  
  Call Number refbase @ user @ Serial 118  
Permanent link to this record
 

 
Author Weik, H.; Altmann, J. openurl 
  Title The effect of L(+)-lactate on rat and horse adipose tissue in vitro Type Journal Article
  Year 1972 Publication Zentralblatt fur Veterinarmedizin. Reihe A Abbreviated Journal Zentralbl Veterinarmed A  
  Volume 19 Issue 6 Pages 514-518  
  Keywords Adipose Tissue/analysis/*drug effects; Animals; Fatty Acids, Nonesterified; Glycerol/metabolism; Horses; Lactates/*pharmacology; Lipid Metabolism; Male; Rats  
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  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0514-7158 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:4626300 Approved no  
  Call Number refbase @ user @ Serial 132  
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Author Altmann, H.J.; Weik, H. openurl 
  Title [Serum fatty acid patterns of phospholipid fractions in horses] Type Journal Article
  Year 1971 Publication Zeitschrift fur Tierphysiologie, Tierernahrung und Futtermittelkunde Abbreviated Journal Z Tierphysiol Tierernahr Futtermittelkd  
  Volume 28 Issue 5 Pages 285-288  
  Keywords Animals; Chromatography, Thin Layer; Fatty Acids/*blood; *Horses; Male; Phospholipids/*blood  
  Abstract  
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  Language German Summary Language Original Title Fettsaurenmuster der Phospholipidfraktionen im plasma des Pferdes  
  Series Editor Series Title Abbreviated Series Title (up)  
  Series Volume Series Issue Edition  
  ISSN 0044-3565 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:5141052 Approved no  
  Call Number refbase @ user @ Serial 133  
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