Records |
Author |
Matzke, S.M.; Oubre, J.L.; Caranto, G.R.; Gentry, M.K.; Galbicka, G. |
Title |
Behavioral and immunological effects of exogenous butyrylcholinesterase in rhesus monkeys |
Type |
Journal Article |
Year |
1999 |
Publication |
Pharmacology, Biochemistry, and Behavior |
Abbreviated Journal |
Pharmacol Biochem Behav |
Volume |
62 |
Issue |
3 |
Pages |
523-530 |
Keywords |
Animals; Antibody Formation/drug effects; Behavior, Animal/*drug effects; Butyrylcholinesterase/*immunology/pharmacokinetics/*pharmacology; Cognition/drug effects; Color Perception/drug effects; Conditioning, Operant/drug effects; Discrimination Learning/drug effects; Half-Life; Horses; Humans; Macaca mulatta; Male |
Abstract |
Although conventional therapies prevent organophosphate (OP) lethality, laboratory animals exposed to such treatments typically display behavioral incapacitation. Pretreatment with purified exogenous human or equine serum butyrylcholinesterase (Eq-BuChE), conversely, has effectively prevented OP lethality in rats and rhesus monkeys, without producing the adverse side effects associated with conventional treatments. In monkeys, however, using a commercial preparation of Eq-BuChE has been reported to incapacitate responding. In the present study, repeated administration of commercially prepared Eq-BuChE had no systematic effect on behavior in rhesus monkeys as measured by a six-item serial probe recognition task, despite 7- to 18-fold increases in baseline BuChE levels in blood. Antibody production induced by the enzyme was slight after the first injection and more pronounced following the second injection. The lack of behavioral effects, the relatively long in vivo half-life, and the previously demonstrated efficacy of BuChE as a biological scavenger for highly toxic OPs make BuChE potentially more effective than current treatment regimens for OP toxicity. |
Address |
Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA |
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ISSN |
0091-3057 |
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PMID:10080246 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
4064 |
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Author |
Neuringer, A. |
Title |
Reinforced variability in animals and people: implications for adaptive action |
Type |
Journal Article |
Year |
2004 |
Publication |
The American Psychologist |
Abbreviated Journal |
Am Psychol |
Volume |
59 |
Issue |
9 |
Pages |
891-906 |
Keywords |
Animals; Behavior, Animal; *Choice Behavior; Conditioning, Operant; Creativeness; Discrimination (Psychology); Humans; Memory; Problem Solving; *Reinforcement (Psychology) |
Abstract |
Although reinforcement often leads to repetitive, even stereotyped responding, that is not a necessary outcome. When it depends on variations, reinforcement results in responding that is diverse, novel, indeed unpredictable, with distributions sometimes approaching those of a random process. This article reviews evidence for the powerful and precise control by reinforcement over behavioral variability, evidence obtained from human and animal-model studies, and implications of such control. For example, reinforcement of variability facilitates learning of complex new responses, aids problem solving, and may contribute to creativity. Depression and autism are characterized by abnormally repetitive behaviors, but individuals afflicted with such psychopathologies can learn to vary their behaviors when reinforced for so doing. And reinforced variability may help to solve a basic puzzle concerning the nature of voluntary action. |
Address |
Department of Psychology, Reed College, Portland, OR 97202, USA. allen.neuringer@reed.edu |
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English |
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ISSN |
0003-066X |
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Notes |
PMID:15584823 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
4106 |
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Author |
Suzuki, Y.; Toquenaga, Y. |
Title |
Effects of information and group structure on evolution of altruism: analysis of two-score model by covariance and contextual analyses |
Type |
Journal Article |
Year |
2005 |
Publication |
Journal of theoretical biology |
Abbreviated Journal |
J. Theor. Biol. |
Volume |
232 |
Issue |
2 |
Pages |
191-201 |
Keywords |
*Altruism; Analysis of Variance; *Communication; Cooperative Behavior; *Evolution; Game Theory; *Group Structure; Humans; Models, Genetic; Models, Psychological; Selection (Genetics); Trust |
Abstract |
An altruistic individual has to gamble on cooperation to a stranger because it does not know whether the stranger is trustworthy before direct interaction. Nowak and Sigmund (Nature 393 (1998a) 573; J. Theor. Biol. 194 (1998b) 561) presented a new theoretical framework of indirect reciprocal altruism by image scoring game where all individuals are informed about a partner's behavior from its image score without direct interaction. Interestingly, in a simplified version of the image scoring game, the evolutionarily stability condition for altruism became a similar form of Hamilton's rule, i.e. inequality that the probability of getting correct information is more than the ratio of cost to benefit. Since the Hamilton's rule was derived by evolutionarily stable analysis, the evolutionary meaning of the probability of getting correct information has not been clearly examined in terms of kin and group selection. In this study, we applied covariance analysis to the two-score model for deriving the Hamilton's rule. We confirmed that the probability of getting correct information was proportional to the bias of altruistic interactions caused by using information about a partner's image score. The Hamilton's rule was dependent on the number of game bouts even though the information reduced the risk of cooperation to selfish one at the first encounter. In addition, we incorporated group structure to the two-score model to examine whether the probability of getting correct information affect selection for altruism by group selection. We calculated a Hamilton's rule of group selection by contextual analysis. Group selection is very effective when either the probability of getting correct information or that of future interaction, or both are low. The two Hamilton's rules derived by covariance and contextual analyses demonstrated the effects of information and group structure on the evolution of altruism. We inferred that information about a partner's behavior and group structure can produce flexible pathways for the evolution of altruism. |
Address |
Integrative Environmental Sciences, Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1, Ten-Nou-Dai, Tsukuba, Ibaraki 305-8572, Japan. yukari@pe.ies.life.tsukuba.ac.jp |
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ISSN |
0022-5193 |
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Notes |
PMID:15530489 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
556 |
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Author |
Gallup, G.G.J. |
Title |
Do minds exist in species other than our own? |
Type |
Journal Article |
Year |
1985 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
Volume |
9 |
Issue |
4 |
Pages |
631-641 |
Keywords |
Animals; Awareness; *Behavior, Animal; Child Psychology; Child, Preschool; *Cognition; Consciousness; Evolution; Humans; Infant; Language; Pan troglodytes; Philosophy; Psychological Theory; Species Specificity |
Abstract |
An answer to the question of animal awareness depends on evidence, not intuition, anecdote, or debate. This paper examines some of the problems inherent in an analysis of animal awareness, and whether animals might be aware of being aware is offered as a more meaningful distinction. A framework is presented which can be used to make a determination about the extent to which other species have experiences similar to ours based on their ability to make inferences and attributions about mental states in others. The evidence from both humans and animals is consistent with the idea that the capacity to use experience to infer the experience of others is a byproduct of self-awareness. |
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English |
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Edition |
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ISSN |
0149-7634 |
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Conference |
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Notes |
PMID:4080281 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2808 |
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Author |
Pickens, C.L.; Holland, P.C. |
Title |
Conditioning and cognition |
Type |
Journal Article |
Year |
2004 |
Publication |
Neuroscience and Biobehavioral Reviews |
Abbreviated Journal |
Neurosci Biobehav Rev |
Volume |
28 |
Issue |
7 |
Pages |
651-661 |
Keywords |
Animals; Association Learning/physiology; Cognition/*physiology; Conditioning (Psychology)/*physiology; Discrimination Learning/physiology; Humans; Memory; Models, Psychological; Reinforcement (Psychology); Visual Perception/physiology |
Abstract |
Animals' abilities to use internal representations of absent objects to guide adaptive behavior and acquire new information, and to represent multiple spatial, temporal, and object properties of complex events and event sequences, may underlie many aspects of human perception, memory, and symbolic thought. In this review, two classes of simple associative learning tasks that address these core cognitive capacities are discussed. The first set, including reinforcer revaluation and mediated learning procedures, address the power of Pavlovian conditioned stimuli to gain access, through learning, to representations of upcoming events. The second set of investigations concern the construction of complex stimulus representations, as illustrated in studies of contextual learning, the conjunction of explicit stimulus elements in configural learning procedures, and recent studies of episodic-like memory. The importance of identifying both cognitive process and brain system bases of performance in animal models is emphasized. |
Address |
Department of Psychological and Brain Sciences, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218, USA |
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English |
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ISSN |
0149-7634 |
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Notes |
PMID:15555675 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2803 |
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Author |
Cowell, P.E.; Fitch, R.H.; Denenberg, V.H. |
Title |
Laterality in animals: relevance to schizophrenia |
Type |
Journal Article |
Year |
1999 |
Publication |
Schizophrenia Bulletin |
Abbreviated Journal |
Schizophr Bull |
Volume |
25 |
Issue |
1 |
Pages |
41-62 |
Keywords |
Adult; Animals; Cognition; *Disease Models, Animal; Functional Laterality/*physiology; Humans; Language; Motor Activity/physiology; Schizophrenia/*physiopathology |
Abstract |
Anomalies in the laterality of numerous neurocognitive dimensions associated with schizophrenia have been documented, but their role in the etiology and early development of the disorder remain unclear. In the study of normative neurobehavioral organization, animal models have shed much light on the mechanisms underlying and the factors affecting adult patterns of both functional and structural asymmetry. Nonhuman species have more recently been used to investigate the environmental, genetic, and neuroendocrine factors associated with developmental language disorders in humans. We propose that the animal models used to study the basis of lateralization in normative development and language disorders such as dyslexia could be modified to investigate lateralized phenomena in schizophrenia. |
Address |
Dept. of Human Communication Sciences, University of Sheffield, United Kingdom |
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English |
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Edition |
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ISSN |
0586-7614 |
ISBN |
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Notes |
PMID:10098913 |
Approved |
no |
Call Number |
Equine Behaviour @ team @ |
Serial |
2827 |
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Author |
Papakostas, Y.G.; Daras, M.D.; Liappas, I.A.; Markianos, M. |
Title |
Horse madness (hippomania) and hippophobia |
Type |
Journal Article |
Year |
2005 |
Publication |
History of Psychiatry |
Abbreviated Journal |
Hist Psychiatry |
Volume |
16 |
Issue |
Pt 4 (no 64) |
Pages |
467-471 |
Keywords |
Ancient Lands; Animals; Cattle; History, Ancient; Horse Diseases/*history; Horses; Humans; *Mythology |
Abstract |
Anthropophagic horses have been described in classical mythology. From a current perspective, two such instances are worth mentioning and describing: Glaucus of Potniae, King of Efyra, and Diomedes, King of Thrace, who were both devoured by their horses. In both cases, the horses' extreme aggression and their subsequent anthropophagic behaviour were attributed to their madness (hippomania) induced by the custom of feeding them with flesh. The current problem of 'mad cow' disease (bovine spongiform encephalopathy) is apparently related to a similar feed pattern. Aggressive behaviour in horses can be triggered by both biological and psychological factors. In the cases cited here, it is rather unlikely that the former were the cause. On the other hand, the multiple abuses imposed on the horses, coupled with people's fantasies and largely unconscious fears (hippophobia), may possibly explain these mythological descriptions of 'horse-monsters'. |
Address |
Athens University Medical School |
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English |
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ISSN |
0957-154X |
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Notes |
PMID:16482685 |
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no |
Call Number |
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Serial |
1876 |
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Author |
Seyfarth, R.M.; Cheney, D.L.; Bergman, T.J. |
Title |
Primate social cognition and the origins of language |
Type |
Journal Article |
Year |
2005 |
Publication |
Trends in Cognitive Sciences |
Abbreviated Journal |
Trends. Cognit. Sci. |
Volume |
9 |
Issue |
6 |
Pages |
264-266 |
Keywords |
Animals; *Cognition; Humans; *Language; Papio; Psychological Theory; Social Behavior; *Social Perception |
Abstract |
Are the cognitive mechanisms underlying language unique, or can similar mechanisms be found in other domains? Recent field experiments demonstrate that baboons' knowledge of their companions' social relationships is based on discrete-valued traits (identity, rank, kinship) that are combined to create a representation of social relations that is hierarchically structured, open-ended, rule-governed, and independent of sensory modality. The mechanisms underlying language might have evolved from the social knowledge of our pre-linguistic primate ancestors. |
Address |
Departments of Biology and Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA. seyfarth@psych.upenn.edu |
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ISSN |
1364-6613 |
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PMID:15925802 |
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no |
Call Number |
refbase @ user @ |
Serial |
343 |
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Author |
Whiten, A.; Goodall, J.; McGrew, W.C.; Nishida, T.; Reynolds, V.; Sugiyama, Y.; Tutin, C.E.; Wrangham, R.W.; Boesch, C. |
Title |
Cultures in chimpanzees |
Type |
Journal Article |
Year |
1999 |
Publication |
Nature |
Abbreviated Journal |
Nature |
Volume |
399 |
Issue |
6737 |
Pages |
682-685 |
Keywords |
Animals; *Behavior, Animal; Cognition; *Culture; Humans; Pan troglodytes/*physiology; Species Specificity |
Abstract |
As an increasing number of field studies of chimpanzees (Pan troglodytes) have achieved long-term status across Africa, differences in the behavioural repertoires described have become apparent that suggest there is significant cultural variation. Here we present a systematic synthesis of this information from the seven most long-term studies, which together have accumulated 151 years of chimpanzee observation. This comprehensive analysis reveals patterns of variation that are far more extensive than have previously been documented for any animal species except humans. We find that 39 different behaviour patterns, including tool usage, grooming and courtship behaviours, are customary or habitual in some communities but are absent in others where ecological explanations have been discounted. Among mammalian and avian species, cultural variation has previously been identified only for single behaviour patterns, such as the local dialects of song-birds. The extensive, multiple variations now documented for chimpanzees are thus without parallel. Moreover, the combined repertoire of these behaviour patterns in each chimpanzee community is itself highly distinctive, a phenomenon characteristic of human cultures but previously unrecognised in non-human species. |
Address |
Scottish Primate Research Group, School of Psychology, University of St Andrews, UK |
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English |
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ISSN |
0028-0836 |
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PMID:10385119 |
Approved |
no |
Call Number |
refbase @ user @ |
Serial |
742 |
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Author |
McCrory, P.; Turner, M.; LeMasson, B.; Bodere, C.; Allemandou, A. |
Title |
An analysis of injuries resulting from professional horse racing in France during 1991-2001: a comparison with injuries resulting from professional horse racing in Great Britain during 1992-2001 |
Type |
Journal Article |
Year |
2006 |
Publication |
British Journal of Sports Medicine |
Abbreviated Journal |
Br J Sports Med |
Volume |
40 |
Issue |
7 |
Pages |
614-618 |
Keywords |
Accidental Falls/statistics & numerical data; Accidents, Occupational/statistics & numerical data; Animals; Athletic Injuries/*epidemiology/etiology; Female; France/epidemiology; Great Britain/epidemiology; *Horses; Humans; Incidence; Ireland/epidemiology; Male; Prospective Studies |
Abstract |
BACKGROUND: It has been previously shown that professional jockeys suffer high rates of fatal and non-fatal injuries in the pursuit of their occupation. Little is known, however, about differences in injury rates between countries. AIM: To determine the rate of fatal and non-fatal injuries in flat and jump jockeys in France and to compare the injury rates with those in Great Britain and Ireland Method: Prospectively collected injury data on professional jockeys were used as the basis of the analysis. RESULTS: Limb fractures occur four times more often in both flat and jump racing in France than in Great Britain. Similarly dislocations are diagnosed 20 times more often in flat and three times more often in jump racing. This difference is surprising given that French jockeys have fewer falls per ride than their British counterparts in flat racing, although they do have more falls than the British in jump racing. Similarly concussion rates seem to be higher in French jockeys, although there may be a difference in the diagnostic methods used in the different countries. By contrast, soft tissue injuries account for a far smaller percentage of injuries than in Great Britain. CONCLUSION: There are striking differences in injury rates between countries which may be explained in part by a difference in track conditions-for example, harder tracks in France-or different styles of racing--for example, larger fields of horses per race in France. |
Address |
Centre for Health, Exercise and Sports Medicine and Brain Research Institute, University of Melbourne, Parkville, Victoria, Australia. paulmccr@bigpond.net.au |
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Edition |
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ISSN |
1473-0480 |
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Notes |
PMID:16687479 |
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no |
Call Number |
Equine Behaviour @ team @ |
Serial |
3762 |
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