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| Author | Domjan, M. | ||||
| Title | Selective suppression of drinking during a limited period following aversive drug treatment in rats | Type | Journal Article | ||
| Year | 1977 | Publication | Journal of Experimental Psychology. Animal Behavior Processes | Abbreviated Journal | J Exp Psychol Anim Behav Process |
| Volume | 3 | Issue | 1 | Pages | 66-76 |
| Keywords | Animals; *Avoidance Learning; Awareness; Conditioning, Operant; Dose-Response Relationship, Drug; Drinking Behavior/*drug effects; Lithium/*poisoning; Male; Osmolar Concentration; Rats; Saccharin/administration & dosage; *Taste; Time Factors | ||||
| Abstract | Administration of lithium chloride disrupted the intake of flavored solutions but not water in rats. This intake suppression was directly related to the amount of lithium administered (Experiment 1), occurred with both palatable and unpalatable novel saccharin solutions (Experiment 2), but was only observed if subjects were tested starting less than 75 min. after lithium treatment (Experiment 3). Twenty-five daily exposures to saccharin did not attenuate the effect (Experiment 4). However, in saccharin-reared and vinegar-reared rats, lithium did not disrupt consumption of the solutions these subjects had access to throughout life, even though suppressions of intake were observed when these subjects were tested with novel flavors (Experiment 5). The selective disruption of drinking is interpreted as a novelty-dependent sensitization reaction to the discomfort of aversive drug administration. | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 0097-7403 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:845544 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 2788 | ||
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