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Author Atock, M.A.; Williams, R.B. openurl 
  Title Welfare of competition horses Type Journal Article
  Year 1994 Publication Revue Scientifique et Technique (International Office of Epizootics) Abbreviated Journal Rev Sci Tech  
  Volume 13 Issue 1 Pages 217-232  
  Keywords *Animal Welfare; Animals; Doping in Sports; Ethics; Heat; Horses/*physiology; Housing, Animal/standards; Humidity; International Cooperation; Sports/*standards; Transportation/standards; Veterinary Medicine  
  Abstract In the large majority of cases and circumstances, horses benefit from their association with man. However, abuse of horses can occur, due to neglect or through the pressures of competition. The welfare of all animals, including competition horses, has become increasingly topical over the past ten years. Equestrian sport is coming under closer public scrutiny due to reports of apparent abuse. The bodies responsible for regulating these sports strenuously endeavour to protect the welfare of horses which compete under their rules and regulations. The Federation Equestre Internationale (FEI: International Equestrian Federation) is the sole authority for all international events in dressage, show-jumping, three-day event, driving, endurance riding and vaulting. The FEI rules illustrate the ways in which the welfare of competing horses is safeguarded.  
  Address Federation Equestre Internationale, Lausanne, Switzerland  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0253-1933 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:8173097 Approved no  
  Call Number Equine Behaviour @ team @ Serial 3747  
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Author Hodgson, D.; Howe, S.; Jeffcott, L.; Reid, S.; Mellor, D.; Higgins, A. doi  openurl
  Title Effect of prolonged use of altrenogest on behaviour in mares Type
  Year 2005 Publication Veterinary journal (London, England : 1997) Abbreviated Journal Vet J  
  Volume 169 Issue 1 Pages 113-115  
  Keywords Administration, Oral; Anabolic Agents/adverse effects/*pharmacology; Animals; Behavior, Animal/*drug effects; Body Constitution/drug effects; Body Weight/drug effects; *Doping in Sports; Female; Horses/*physiology; Social Behavior; Social Dominance; Time Factors; Trenbolone/adverse effects/*analogs & derivatives/*pharmacology  
  Abstract Erratum in:

Vet J. 2005 May;169(3):321.

Corrected and republished in:

Vet J. 2005 May;169(3):322-5.

Oral administration of altrenogest for oestrus suppression in competition horses is believed to be widespread in some equestrian disciplines, and can be administered continuously for several months during a competition season. To examine whether altrenogest has any anabolic or other potential performance enhancing properties that may give a horse an unfair advantage, we examined the effect of oral altrenogest (0.044 mg/kg), given daily for a period of eight weeks, on social hierarchy, activity budget, body-mass and body condition score of 12 sedentary mares. We concluded that prolonged oral administration of altrenogest at recommended dose rates to sedentary mares resulted in no effect on dominance hierarchies, body mass or condition score.
 
  Address Faculty of Veterinary Science, University of Sydney, Private Mailbag 4, Narellan Delivery Centre, Narellan, NSW 2567, Australia. davidh@camden.usyd.edu.au  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1090-0233 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:15683772 Approved no  
  Call Number refbase @ user @ Serial 671  
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Author Machnik, M.; Hegger, I.; Kietzmann, M.; Thevis, M.; Guddat, S.; Schanzer, W. doi  openurl
  Title Pharmacokinetics of altrenogest in horses Type Journal Article
  Year 2007 Publication Journal of Veterinary Pharmacology and Therapeutics Abbreviated Journal J Vet Pharmacol Ther  
  Volume 30 Issue 1 Pages 86-90  
  Keywords Administration, Oral; Animals; Chromatography, Liquid/veterinary; Doping in Sports/prevention & control; Horses/*metabolism; Male; Mass Spectrometry/veterinary; Progesterone Congeners/administration & dosage/blood/*pharmacokinetics/urine; Reproducibility of Results; Substance Abuse Detection/veterinary; Trenbolone/administration & dosage/*analogs & derivatives/blood/pharmacokinetics/urine  
  Abstract The Federation Equestre Internationale has permitted the use of altrenogest in mares for the control of oestrus. However, altrenogest is also suspicious to misuse in competition horses for its potential anabolic effects and suppression of typical male behaviour, and thus is a controlled drug. To investigate the pharmacokinetics of altrenogest in horses we conducted an elimination study. Five oral doses of 44 mug/kg altrenogest were administered to 10 horses at a dose interval of 24 h. Following administration blood and urine samples were collected at appropriate intervals. Altrenogest concentrations were measured by liquid chromatography-tandem mass spectrometry. The plasma levels of altrenogest reached maximal concentrations of 23-75 ng/mL. Baseline values were achieved within 3 days after the final administration. Urine peak concentrations of total altrenogest ranged from 823 to 3895 ng/mL. Twelve days after the final administration concentrations were below the limit of detection (ca 2 ng/mL).  
  Address Institute of Biochemistry, German Sport University, Cologne, Germany. m.machnik@biochem.dshs-koeln.de  
  Corporate Author Thesis  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0140-7783 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:17217407 Approved no  
  Call Number Serial 1841  
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