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| Author | Hodgson, D.; Howe, S.; Jeffcott, L.; Reid, S.; Mellor, D.; Higgins, A. | ||||
| Title | Effect of prolonged use of altrenogest on behaviour in mares | Type | |||
| Year | 2005 | Publication | Veterinary journal (London, England : 1997) | Abbreviated Journal | Vet J |
| Volume | 169 | Issue | 1 | Pages | 113-115 |
| Keywords | Administration, Oral; Anabolic Agents/adverse effects/*pharmacology; Animals; Behavior, Animal/*drug effects; Body Constitution/drug effects; Body Weight/drug effects; *Doping in Sports; Female; Horses/*physiology; Social Behavior; Social Dominance; Time Factors; Trenbolone/adverse effects/*analogs & derivatives/*pharmacology | ||||
| Abstract | Erratum in: Vet J. 2005 May;169(3):321. Corrected and republished in: Vet J. 2005 May;169(3):322-5. Oral administration of altrenogest for oestrus suppression in competition horses is believed to be widespread in some equestrian disciplines, and can be administered continuously for several months during a competition season. To examine whether altrenogest has any anabolic or other potential performance enhancing properties that may give a horse an unfair advantage, we examined the effect of oral altrenogest (0.044 mg/kg), given daily for a period of eight weeks, on social hierarchy, activity budget, body-mass and body condition score of 12 sedentary mares. We concluded that prolonged oral administration of altrenogest at recommended dose rates to sedentary mares resulted in no effect on dominance hierarchies, body mass or condition score. |
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| Address | Faculty of Veterinary Science, University of Sydney, Private Mailbag 4, Narellan Delivery Centre, Narellan, NSW 2567, Australia. davidh@camden.usyd.edu.au | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language | Original Title | ||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 1090-0233 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:15683772 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 671 | ||
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| Author | Matzke, S.M.; Oubre, J.L.; Caranto, G.R.; Gentry, M.K.; Galbicka, G. | ||||
| Title | Behavioral and immunological effects of exogenous butyrylcholinesterase in rhesus monkeys | Type | Journal Article | ||
| Year | 1999 | Publication | Pharmacology, Biochemistry, and Behavior | Abbreviated Journal | Pharmacol Biochem Behav |
| Volume | 62 | Issue | 3 | Pages | 523-530 |
| Keywords | Animals; Antibody Formation/drug effects; Behavior, Animal/*drug effects; Butyrylcholinesterase/*immunology/pharmacokinetics/*pharmacology; Cognition/drug effects; Color Perception/drug effects; Conditioning, Operant/drug effects; Discrimination Learning/drug effects; Half-Life; Horses; Humans; Macaca mulatta; Male | ||||
| Abstract | Although conventional therapies prevent organophosphate (OP) lethality, laboratory animals exposed to such treatments typically display behavioral incapacitation. Pretreatment with purified exogenous human or equine serum butyrylcholinesterase (Eq-BuChE), conversely, has effectively prevented OP lethality in rats and rhesus monkeys, without producing the adverse side effects associated with conventional treatments. In monkeys, however, using a commercial preparation of Eq-BuChE has been reported to incapacitate responding. In the present study, repeated administration of commercially prepared Eq-BuChE had no systematic effect on behavior in rhesus monkeys as measured by a six-item serial probe recognition task, despite 7- to 18-fold increases in baseline BuChE levels in blood. Antibody production induced by the enzyme was slight after the first injection and more pronounced following the second injection. The lack of behavioral effects, the relatively long in vivo half-life, and the previously demonstrated efficacy of BuChE as a biological scavenger for highly toxic OPs make BuChE potentially more effective than current treatment regimens for OP toxicity. | ||||
| Address | Walter Reed Army Institute of Research, Washington, DC 20307-5100, USA | ||||
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| Language | English | Summary Language | Original Title | ||
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| Series Volume | Series Issue | Edition | |||
| ISSN | 0091-3057 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:10080246 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 4064 | ||
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| Author | Tobin, T.; Combie, J.D. | ||||
| Title | Performance testing in horses: a review of the role of simple behavioral models in the design of performance experiments | Type | Journal Article | ||
| Year | 1982 | Publication | Journal of Veterinary Pharmacology and Therapeutics | Abbreviated Journal | J Vet Pharmacol Ther |
| Volume | 5 | Issue | 2 | Pages | 105-118 |
| Keywords | Analgesics, Opioid/pharmacology; Animals; Apomorphine/pharmacology; Behavior, Animal/*drug effects; Dose-Response Relationship, Drug; Fentanyl/pharmacology; Horses/*physiology; Methylphenidate/pharmacology; *Models, Biological; Motor Activity/drug effects | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language | Original Title | ||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 0140-7783 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:6125601 | Approved | no | ||
| Call Number | refbase @ user @ | Serial | 1957 | ||
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| Author | Yamazaki, Y.; Shinohara, N.; Watanabe, S. | ||||
| Title | Visual discrimination of normal and drug induced behavior in quails (Coturnix coturnix japonica) | Type | Journal Article | ||
| Year | 2004 | Publication | Animal Cognition | Abbreviated Journal | Anim. Cogn. |
| Volume | 7 | Issue | 2 | Pages | 128-132 |
| Keywords | Animals; Behavior, Animal/*drug effects; Classification; Coturnix/*physiology; *Discrimination Learning; *Generalization (Psychology); Ketamine/pharmacology; Male; Methamphetamine/pharmacology; *Pattern Recognition, Visual; Video Recording; Visual Perception | ||||
| Abstract | The ability to discriminate the physical states of others could be an adaptive behavior, especially for social animals. For example, the ability to discriminate illness behavior would be helpful for avoiding spoiled foods. We report on an experiment with Japanese quails testing whether these birds can discriminate the physical states of conspecifics. The quails were trained to discriminate between moving video images of quails injected with psychoactive drugs and those in a normal (not injected) condition. Methamphetamine (stimulant) or ketamine (anesthetic) were used to produce drug-induced behaviors in conspecifics. The former induced hyperactive behavior and the latter hypoactive behavior. The subject quails could learn the discrimination and showed generalization to novel images of the drug-induced behaviors. They did not, however, show discriminative behavior according to the type and dosage of the drugs. Thus, they categorized the behavior not on the basis of degree of activity, but on the basis of abnormality. | ||||
| Address | Biopsychologie, Institut fur Kognitive Neurowissenschaft, Fakultat fur Psychologie, Ruhr-Universitat Bochum, 44780 Bochum, Germany. yumyam@bio.psy.ruhr-uni-bochum.de | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language | Original Title | ||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 1435-9448 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:15069613 | Approved | no | ||
| Call Number | Equine Behaviour @ team @ | Serial | 2527 | ||
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| Author | Zehnder, A.M.; Ramer, J.C.; Proudfoot, J.S. | ||||
| Title | The use of altrenogest to control aggression in a male Grant's Zebra (Equus burchelli boehmi) | Type | Journal Article | ||
| Year | 2006 | Publication | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians | Abbreviated Journal | J Zoo Wildl Med |
| Volume | 37 | Issue | 1 | Pages | 61-63 |
| Keywords | Aggression/*drug effects; Animals; Animals, Zoo; Behavior, Animal/*drug effects; Dose-Response Relationship, Drug; Equidae/*physiology; Female; Horses; Male; Treatment Outcome; Trenbolone/*analogs & derivatives/therapeutic use | ||||
| Abstract | A male Grant's Zebra (Equus burchelli boehmi) housed with two mares at the Indianapolis Zoo had a 9-yr history of intermittent aggressive behavior toward mares and other animals. Periods of separation allowed the mares time to heal after sustaining superficial bite wounds. On 26 March 2003, the male (890293) was started on altrenogest at a dosage of 19.8 mg orally once daily to allow reintroduction. The dosage was doubled (40 mg once a day) because of a perceived lack of response. Reintroduction to the mares occurred on 17 May 2003 with no signs of aggression noted. Treatment was reduced to 19.8 mg orally once a day and then discontinued. Altrenogest was restarted at 39.5 mg orally once a day because of the planned introduction of a new mare. There have been no major aggressive displays at this dosage of altrenogest and the dosage has recently been reduced following successful introduction of a new mare. | ||||
| Address | University of Florida, 2015 SW 16th Street, Gainesville, Florida 32610, USA | ||||
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| Publisher | Place of Publication | Editor | |||
| Language | English | Summary Language | Original Title | ||
| Series Editor | Series Title | Abbreviated Series Title | |||
| Series Volume | Series Issue | Edition | |||
| ISSN | 1042-7260 | ISBN | Medium | ||
| Area | Expedition | Conference | |||
| Notes | PMID:17312816 | Approved | no | ||
| Call Number | Serial | 1772 | |||
| Permanent link to this record | |||||