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Author |
Saigo, S. |
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Title |
Kinetic and equilibrium studies of alkaline isomerization of vertebrate cytochromes c |
Type |
Journal Article |
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Year |
1981 |
Publication |
Biochimica et Biophysica Acta |
Abbreviated Journal |
Biochim Biophys Acta |
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Volume |
669 |
Issue |
1 |
Pages |
13-20 |
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Keywords |
Amino Acid Sequence; Animals; Cytochrome c Group/*metabolism; Dogs; Hydrogen-Ion Concentration; Isomerism; Kinetics; Vertebrates/metabolism |
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Abstract |
Equilibria and kinetics of alkaline isomerization of seven ferricytochromes c from vertebrates were studied by pH-titration and pH-jump methods in the pH region of 7-12. In the equilibrium behavior, no significant difference was detected among the cytochromes c, whereas marked differences in the kinetic behavior were observed. According to the kinetic behavior of the isomerization, the cytochromes c examined fall into three classes: Group I (horse, sheep, dog and pigeon cytochromes c), Group II (tuna and bonito cytochromes c) and Group III (rhesus monkey cytochrome c). The kinetic results are interpreted in terms of the sequential scheme: Neutral form in equilibrium with fast Transient form in equilibrium with slow Alkaline form where the neutral and alkaline forms are the species stable at neutral and alkaline pH, respectively, and the transient form is a kinetic intermediate. From comparison of the primary sequences of the seven cytochromes c and the classification of these cytochromes c, it is concluded that the amino acid substitution Phe/Tyr at the 46-th position has a major influence on the kinetic behavior. In Group II and III cytochromes c, the ionization of Tyr-46 is suggested to bring about loosening of the heme crevice and thus facilitate the ligand replacement involved in the isomerization. |
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0006-3002 |
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PMID:6271238 |
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no |
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Call Number |
refbase @ user @ |
Serial |
3871 |
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Author |
Boice, R. |
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Title |
Behavioral comparability of wild and domesticated rats |
Type |
Journal Article |
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Year |
1981 |
Publication |
Behavior Genetics |
Abbreviated Journal |
Behav Genet |
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Volume |
11 |
Issue |
5 |
Pages |
545-553 |
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Keywords |
Animals; *Behavior, Animal; Female; Genetics, Behavioral; Intelligence; Learning; Male; Rats/*genetics |
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Abstract |
The oft-repeated concern for the lack of behavioral comparability of domestic rats with wild forms of Rattus norvegicus is unfounded. Laboratory rats appear to show the potential for all wild-type behaviors, including the most dramatic social postures. Moreover, domestics are capable of assuming a feral existence without difficulty, one where they readily behave in a fashion indistinguishable from wild rats. The one behavioral difference that is clearly established concerns performance in laboratory learning paradigms. The superiority of domestics in these laboratory tasks speaks more to quieting the concerns of degeneracy theorists than to problems of using domestic Norway rats as subjects representative of their species. |
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0001-8244 |
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PMID:7325955 |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4144 |
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Author |
Hoff, M.P.; Nadler, R.D.; Maple, T.L. |
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Title |
Development of infant independence in a captive group of lowland gorillas |
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Journal Article |
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Year |
1981 |
Publication |
Developmental Psychobiology |
Abbreviated Journal |
Dev Psychobiol |
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Volume |
14 |
Issue |
3 |
Pages |
251-265 |
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Keywords |
Animals; *Dependency (Psychology); Female; Gorilla gorilla/*growth & development; Male; Maternal Behavior; *Personality; Sex Factors; Social Behavior; Weaning |
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Abstract |
In March 1976, 3 lowlands gorillas (Gorilla gorilla gorilla) were born to primiparous females living with an adult male in a large compound at the field station of the Yerkes Regional Primate Research Center of Emory University. Observations of parent and infant behavior began at the birth of the infants, using several methods of data collection. This report focuses on the development of independence in these infants over the 1st 1 1/2 years of life. As expected, measures of mother-infant contact and proximity decreased with age. Several measures suggested that infant independence developed as an interactive process between mothers and infants, with primary responsibility changing over the months of study. Maternal behaviors that served to maintain mother-infant contact were found to decrease with age, with an eventual shift to infant responsibility for contact maintenance. Additionally, the adult male appeared to influence developing independence as reflected in the maternal protectiveness evoked by his behavior. |
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0012-1630 |
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PMID:7262467 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4170 |
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Author |
Bernstein, I.S.; Dobrofsky, M. |
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Title |
Compensatory social responses of older pigtailed monkeys to maternal separation |
Type |
Journal Article |
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Year |
1981 |
Publication |
Developmental Psychobiology |
Abbreviated Journal |
Dev Psychobiol |
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Volume |
14 |
Issue |
2 |
Pages |
163-168 |
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Keywords |
Animals; Dependency (Psychology); Female; Macaca nemestrina; Male; *Maternal Deprivation; *Social Behavior |
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Abstract |
Thirteen 3-5-year-old pigtailed monkeys were subjected to five 2-hr maternal separations while remaining in their normal social group. Significant changes in activity profiles were noted during separation and reunion phases. This suggests the continued social dependence of older offspring upon the matriarch. The shift in social activities reflected attempts by the juvenile and adolescent subjects to compensate for maternal absence by intensification of other affiliative social behavior and avoidance of potentially socially disruptive situation. The subjects oriented more towards kin in the absence of the matriarch, but actual time with kin decreased. Upon the return of the matriarch, the intensified some responses depressed during her absence and returned to preseparation social relationships. Play and aggressive responses declined whereas social approaches increased during maternal absences. Submissive responses declined upon the return of the matriarch, and play increased. The subjects also showed a marked, temporary increase of direct interaction, largely sniffing and grooming, with the matriarch upon her return. |
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0012-1630 |
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Notes |
PMID:7202854 |
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no |
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Call Number |
Equine Behaviour @ team @ |
Serial |
4171 |
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Author |
Houpt, K.A.; Parsons, M.S.; Hintz, H.F. |
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Title |
Learning ability of orphan foals, of normal foals and of their mothers |
Type |
Journal Article |
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Year |
1982 |
Publication |
Journal of animal science |
Abbreviated Journal |
J. Anim Sci. |
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Volume |
55 |
Issue |
5 |
Pages |
1027-1032 |
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Keywords |
Age Factors; Animals; Body Weight; Dominance-Subordination; Female; Horses/*physiology; *Learning; *Maternal Deprivation; Mothers/*psychology |
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Abstract |
The maze learning ability of six pony foals that had been weaned at birth was compared to that of six foals reared normally. The foals' learning ability was also compared to their mothers' learning ability at the same task; the correct turn in a single choice point maze. The maze learning test was conducted when the foals were 6 to 8 mo old and after the mothered foals had been weaned. There was no significant difference between the ability of orphaned (weaned at birth) and mothered foals in their ability to learn to turn left (6 +/- .7 and 5.1 +/- .1 trials, respectively) or to learn the reversal, to turn right (6.7 +/- .6 and 6.2 +/- .6 trials, respectively). The orphan foals spent significantly more time in the maze in their first exposure to it than the mothered foals (184 +/- 42 vs 55 +/- 15 s. Mann Whitney U = 7, P less than .05). The mothers of the foals (n = 11) learned to turn left as rapidly as the foals (5.9 +/- .7 trials), but they were slower to learn to turn right (9.8 +/- 1.4 vs 6.4 +/- .4 trials, Mann Whitney U = 33, P less than .05), indicating that the younger horses learned more rapidly. There was no correlation between the trials to criteria of the mare and those of her foal, but there was a significant negative correlation between rank in trials to criteria and age (r = -65, P less than .05) when data from the mare and foal trials were combined. The dominance hierarchy of the mares was determined using a paired feeding test in which two horses competed for one bucket of feed. Although there was no correlation between rank in the hierarchy and maze learning ability, there was a correlation between body weight and rank in the hierarchy (r = .7, P less than .05). This may indicate either that heavier horses are likely to be dominant or that horses high in dominance gain more weight. Maternal deprivation did not appear to seriously retard learning of a simple maze by foals, although the orphans moved more slowly initially. The lack of maternal influence on learning is also reflected in the lack of correlation between the mare's learning ability and that of her foal. Young horses appear to learn more rapidly than older horses. |
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0021-8812 |
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Notes |
PMID:7174546 |
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no |
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Call Number |
refbase @ user @ |
Serial |
58 |
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Author |
Alexander, F. |
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Title |
Effect of phenylbutazone on electrolyte metabolism in ponies |
Type |
Journal Article |
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Year |
1982 |
Publication |
The Veterinary record |
Abbreviated Journal |
Vet. Rec. |
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Volume |
110 |
Issue |
12 |
Pages |
271-272 |
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Keywords |
Animals; Chlorides/metabolism; Electrolytes/*metabolism; Horses/*metabolism; Male; Phenylbutazone/*pharmacology; Sodium/metabolism |
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Abstract |
Phenylbutazone administered in therapeutic doses to ponies decreased urinary sodium and chloride excretion. The volume and osmolality of the urine was unaffected as was potassium excretion. Faecal excretion of chloride decreased and that of potassium increased, while faecal sodium excretion was unaffected. Plasma pH, bicarbonate and total carbon dioxide decreased after phenylbutazone administration. Packed cell volume, plasma sodium, potassium, carbon dioxide tension and chloride were unchanged. |
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ISSN |
0042-4900 |
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PMID:7080416 |
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no |
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refbase @ user @ |
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109 |
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Author |
Turner, J.W.J.; Kirkpatrick, J.F. |
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Title |
Androgens, behaviour and fertility control in feral stallions |
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Journal Article |
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Year |
1982 |
Publication |
Journal of reproduction and fertility. Supplement |
Abbreviated Journal |
J Reprod Fertil Suppl |
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Volume |
32 |
Issue |
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Pages |
79-87 |
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Keywords |
Animals; Animals, Wild; Copulation/drug effects; Female; *Fertility/drug effects; Horses/*physiology; Male; Periodicity; Pregnancy; Seasons; *Sexual Behavior, Animal/drug effects; Sexual Maturation; Sperm Count; Sperm Motility/drug effects; Testosterone/*blood/pharmacology |
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Abstract |
This field study of feral stallions in Montana and Idaho examines and correlates the seasonal pattern of plasma androgens and specific sociosexual behaviour and reports the effect of a long-acting androgenic steroid on this behaviour and on fertility. Plasma testosterone was measured by competitive protein binding assay in samples obtained by jugular venepuncture from captured animals. In samples taken from 34 sexually mature stallions in 6 different months during the year, a definite seasonal pattern in testosterone was present, with a peak in May (3.04 +/- 0.63 ng/ml) and a nadir in December (1.55 +/- 0.34 ng/ml). Values were less than 2.0 ng/ml in non-breeding months and greater than 2.4 ng/ml in breeding months. Behavioural endpoints measured were (1) stallion scent marking in response to elimination by mares (elimination marking), (2) mounting and (3) copulation. The frequencies of each of these endpoints followed closely the seasonal pattern seen for plasma androgens. In the fertility study microcapsulated testosterone propionate (microTP) was administered i.m. to 10 harem stud stallions 3 months before the 1980 breeding season. In these stallions and in 10 control harem studs, the above behavioural endpoints were examined in the 1980 and 1981 breeding seasons, and foal counts were made in 1981. There were no direct inhibitory or stimulatory effects of microTP treatment on any of the behavioural endpoints in either year. In 1981 foals were produced in 87.5% of the control bands and 28.4% of the microTP-treated bands. These results indicate that microencapsulated testosterone propionate can provide effective fertility control in feral horses without causing significant alterations in sociosexual behaviour. |
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ISSN |
0449-3087 |
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Notes |
PMID:6962905 |
Approved |
no |
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Call Number |
refbase @ user @ |
Serial |
138 |
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Author |
Shettleworth, S.J.; Krebs, J.R. |
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Title |
How marsh tits find their hoards: the roles of site preference and spatial memory |
Type |
Journal Article |
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Year |
1982 |
Publication |
Journal of experimental psychology. Animal behavior processes |
Abbreviated Journal |
J Exp Psychol Anim Behav Process |
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Volume |
8 |
Issue |
4 |
Pages |
354-375 |
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Keywords |
Animals; *Appetitive Behavior; Birds; Cues; Discrimination Learning; *Memory; *Mental Recall; *Orientation; *Space Perception |
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Abstract |
Marsh tits (Parus palustris) store single food items in scattered locations and recover them hours or days later. Some properties of the spatial memory involved were analyzed in two laboratory experiments. In the first, marsh tits were offered 97 sites for storing 12 seeds. They recovered a median of 65% of them 2-3 hr later, making only two errors per seed while doing so. Over trials, they used some sites more often than others, but during recovery they were more likely to visit a site of any preference value if they had stored a seed there that day than if they had not. Recovery performance was much worse if the experimenters moved the seeds between storage and recovery. A fixed search strategy that had some of the same average properties as the tits' search behavior also did worse than the real birds. In Experiment 2, any tendency to visit the same sites on successive daily tests in the aviary was placed in opposition to memory for storage sites by allowing the tits to store more seeds 2 hr after storing a first batch. They tended to avoid individual storage sites holding seeds from the first batch. When the tits searched for all the seeds 2 hr later, they tended to recover more seeds from the second batch than from the first, i.e., there was a recency effect. |
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0097-7403 |
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PMID:7175447 |
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no |
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Call Number |
refbase @ user @ |
Serial |
385 |
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Author |
Tobin, T.; Combie, J.D. |
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Title |
Performance testing in horses: a review of the role of simple behavioral models in the design of performance experiments |
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Journal Article |
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Year |
1982 |
Publication |
Journal of Veterinary Pharmacology and Therapeutics |
Abbreviated Journal |
J Vet Pharmacol Ther |
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Volume |
5 |
Issue |
2 |
Pages |
105-118 |
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Analgesics, Opioid/pharmacology; Animals; Apomorphine/pharmacology; Behavior, Animal/*drug effects; Dose-Response Relationship, Drug; Fentanyl/pharmacology; Horses/*physiology; Methylphenidate/pharmacology; *Models, Biological; Motor Activity/drug effects |
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ISSN |
0140-7783 |
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PMID:6125601 |
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refbase @ user @ |
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1957 |
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Author |
Klingel, H. |
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Title |
Social organization of feral horses |
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Journal Article |
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Year |
1982 |
Publication |
Journal of Reproduction and Fertility. Supplement |
Abbreviated Journal |
J Reprod Fertil Suppl |
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Volume |
32 |
Issue |
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Pages |
89-95 |
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Keywords |
Animals; Animals, Wild; Female; Horses/*physiology; Male; Sexual Behavior, Animal; *Social Behavior; Territoriality |
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Abstract |
The basic social unit in feral horses is the family group consisting of one stallion, one to a few unrelated mares and their foals. Surplus stallions associate in bachelor groups. Stallions are instrumental in bringing mares together in a unit which then persists even without a stallion. The similarity of social organization in populations living in a variety of different habitats indicates that feral horses have reverted to the habits of their wild ancestors, and that domestication has had no influence on this basic behavioural feature. |
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0449-3087 |
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PMID:6962906 |
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refbase @ user @ |
Serial |
1958 |
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