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Author Morales, J.L.; Manchado, M.; Vivo, J.; Galisteo, A.M.; Aguera, E.; Miro, F.
Title Angular kinematic patterns of limbs in elite and riding horses at trot Type Journal Article
Year 1998 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 30 Issue (down) 6 Pages 528-533
Keywords Animals; Biomechanics; Breeding; Extremities/*physiology; Gait/*physiology; Horses/*physiology; Image Processing, Computer-Assisted; Joints/*physiology; Male; Video Recording
Abstract Normal speed videography was used to determine the angular parameters of 28 Spanish Thoroughbreds at trot. Horses were divided into 3 groups: Group UT, comprising 9 animals (provided by the VII National Stud, Cordoba, Spain) which had undergone no specific training programme and which were hand led at the trot; Group T, formed by 19 horses considered to be highly bred and trained, and which were also hand led; and Group RT, comprising the same horses as the latter group but this time trotted by a rider. Each animal was filmed 6 times from the right-hand side, using a Hi8 (25 Hz) video camera. Angular parameters for fore- and hindlimb joints were measured in each stride from computer-grabbed frames and entered into a spreadsheet for calculation; parameters included maximum and minimum angles, range of motion, and angles at landing, lift off and maximum hoof height; the times at which maximum angle, minimum angle, lift off and maximum hoof height occurred were calculated as percentages of total stride duration. Stride velocity (mean [s.d.]) was 4.01 (0.62), 3.60 (0.34) and 3.07 (0.36) m/s for Groups UT, T and RT, respectively. Data were then compared between Groups UT-T and Groups T-RT. Compared with Group UT, horses from Group T featured a shorter stance percentage (P<0.001) in both fore- and hindlimbs. The range of motion in forelimbs was smaller (P<0.05), due to lower retraction (P<0.001); moreover, maximum retraction appeared earlier (P<0.05). Greater scapular inclination was in evidence (P<0.05) and the shoulder joint extended further (P<0.05). Fore- and hind fetlock joints revealed a relatively shorter hyperextension period during the stance phase (P<0.01). Compared with Group T, horses from Group RT had a longer stance percentage, with belated maximum retraction of the fore- and hindlimbs. The range of movement in scapular inclination was greater (P<0.05), due to a smaller minimum angle (P<0.01), and the shoulder joint flexed more (P<0.05). The elbow joint extended more and for longer during the stance phase. Initial extension of the hip joint (P<0.05) and tarsus (P<0.001) lasted longer. The carpal and fore and hind fetlock joints recorded relatively longer hyperextension times, in addition to greater hyperextension during the stance phase. The results from the present study suggest that rider-effect must be taken in consideration when well gaited horses are selected for dressage purposes.
Address Department of Compared Anatomy and Pathology, University of Cordoba, Veterinary Faculty, Spain
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:9844972 Approved no
Call Number Equine Behaviour @ team @ Serial 3734
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Author Dabareiner, R.M.; Sullins, K.E.; White, N.A. 2nd
Title Progression of femoropatellar osteochondrosis in nine young horses. Clinical, radiographic and arthroscopic findings Type Journal Article
Year 1993 Publication Veterinary Surgery : VS : the Official Journal of the American College of Veterinary Surgeons Abbreviated Journal Vet Surg
Volume 22 Issue (down) 6 Pages 515-523
Keywords Animals; Arthroscopy/veterinary; Debridement/veterinary; Exudates and Transudates; Female; Femur; Follow-Up Studies; Horse Diseases/*diagnosis/radiography/surgery; Horses; Lameness, Animal/*etiology; Male; Osteochondritis/diagnosis/radiography/surgery/*veterinary; Patella; Stifle; Treatment Outcome
Abstract The clinical and radiographic progression, and arthroscopic findings for nine young horses (< 1 year of age) with femoropatellar osteochondrosis (OCD) are presented. Horses had a 2 to 12 week history of bilateral (8 horses) or unilateral (1 horse) hindlimb lameness. The most consistent clinical signs included femoropatellar joint distention and bilateral hindlimb lameness. At the onset of clinical signs, radiographic lesions were not present (4 horses) or subtle (5 horses), but were easily identified on radiographs taken 4 to 24 weeks later. Arthroscopic surgery was delayed until radiographic changes became obvious. Surgical findings in 20 femoropatellar joints were most commonly osteochondral “flaps” located on the proximal lateral trochlear ridge of the femur and were larger than had been indicated by the radiographs. Eight horses were being used for their intended purpose, which was racing (3 horses were racing and 3 were in race training), dressage (1 horse) or pleasure riding (1 horse). One horse required a second surgery when similar lesions developed on the opposite stifle, and was euthanatized 2 months later because of persistent lameness. One clinical signs are observed, osteochondrosis lesions of the distal femur can progress in foals younger than 9 months of age and the full extent of the radiographic lesion may take several weeks to develop.
Address Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg, Virginia
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0161-3499 ISBN Medium
Area Expedition Conference
Notes PMID:8116209 Approved no
Call Number Equine Behaviour @ team @ Serial 3748
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Author Birch, H.L.; Bailey, A.J.; Goodship, A.E.
Title Macroscopic 'degeneration' of equine superficial digital flexor tendon is accompanied by a change in extracellular matrix composition Type Journal Article
Year 1998 Publication Equine Veterinary Journal Abbreviated Journal Equine Vet J
Volume 30 Issue (down) 6 Pages 534-539
Keywords Animals; Collagen/analysis; DNA/analysis; Extracellular Matrix/*chemistry; Glycosaminoglycans/analysis; Horses/injuries/*physiology; Immunohistochemistry; Rupture/veterinary; Tendon Injuries/metabolism/pathology/veterinary; Tendons/chemistry/*pathology; Water/analysis
Abstract Injuries to the superficial digital flexor tendon are common in horses required to gallop and jump at speed. Partial rupture of this tendon usually occurs in the central core of the midmetacarpal region and may be preceded by localised degenerative changes. Post mortem examination of apparently normal equine flexor tendons has revealed an abnormal macroscopic appearance in the central core, characterised by a reddish discolouration. We have previously shown that there is also physical damage to the collagen fibres. In the present study we tested the hypothesis that the abnormal appearance is accompanied by changes in the composition of the extracellular matrix of the tendon. Biochemical analysis of the extracellular matrix demonstrated an increase in total sulphated glycosaminoglycan content, increase in the proportion of type III collagen and decrease in collagen linked fluorescence in the central core of 'degenerated' tendons relative to tissue from the peripheral region of the same tendon. Dry matter content and total collagen content were not significantly different between tendon zones or normal and 'degenerated' tendons. These changes suggest a change in cell metabolism and matrix turnover in the central core of the tendon and are likely to contribute to a decrease in mechanical properties in this part of the tendon, predisposing to the characteristic partial rupture of the tendon.
Address Veterinary Basic Sciences, Royal Veterinary College, North Mymms, Hatfield, UK
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:9844973 Approved no
Call Number Equine Behaviour @ team @ Serial 3794
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Author Steinhoff, H.J.
Title A continuous wave laser T-jump apparatus and its application to chemical reactions in hemoglobin single crystals Type Journal Article
Year 1988 Publication Journal of Biochemical and Biophysical Methods Abbreviated Journal J Biochem Biophys Methods
Volume 15 Issue (down) 6 Pages 319-330
Keywords Animals; Chemistry; Crystallization; *Heat; *Hemoglobins; Horses/blood; *Lasers; Methemoglobin; Solutions; Thermodynamics; Thiocyanates
Abstract A laser temperature jump apparatus is constructed where the T-jump is achieved by means of the direct absorption of continuous laser radiation of low intensity by a solid sample. The final temperature in the irradiated volume element is reached when the absorbed radiation power equals the dissipation of heat by heat conduction. The time range from the beginning of irradiation to the stationary state depends on the geometry of the irradiated volume element and is less than 10 ms. The heating laser beam is simultaneously used to detect the relaxation to the new chemical equilibrium in the sample. Relaxation processes with relaxation rates between 10(2) s-1 and less than 10(-3) s-1 on samples with volumes less than 10(-3) mm3 may be investigated using this T-jump method. One application of this method is the determination of reaction rates of ligand reactions in hemoglobin single crystals. Rate constants obtained for the reaction of thiocyanate with crystallized horse methemoglobin are presented.
Address Institut fur Biophysik, Ruhr-Universitat Bochum, F.R.G
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0165-022X ISBN Medium
Area Expedition Conference
Notes PMID:3379245 Approved no
Call Number Equine Behaviour @ team @ Serial 3804
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Author Saigo, S.
Title A transient spin-state change during alkaline isomerization of ferricytochrome c Type Journal Article
Year 1981 Publication Journal of Biochemistry Abbreviated Journal J Biochem (Tokyo)
Volume 89 Issue (down) 6 Pages 1977-1980
Keywords Animals; *Cytochrome c Group; Horses; Hydrogen-Ion Concentration; Isomerism; Kinetics; Myocardium/enzymology; Oxidation-Reduction; Spectrophotometry
Abstract Kinetic difference spectra during the alkaline isomerization of ferricytochrome c were obtained by the pH-jump method in the range of 540 to 655 nm. The spectrum of the transient intermediate, which appears during the course of the isomerization, was reproduced from the spectra. The intermediate showed an intense absorption band at 600 nm, indicating that it is a high spin or mixed spin species. This is in contrast to the stable neutral and alkaline forms which are low spin species. The transient spin-state change during the isomerization was also observed upon rapid oxidation of ferrocytochrome c at alkaline pH.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0021-924X ISBN Medium
Area Expedition Conference
Notes PMID:6270075 Approved no
Call Number Equine Behaviour @ team @ Serial 3808
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Author Ridge, J.A.; Baldwin, R.L.; Labhardt, A.M.
Title Nature of the fast and slow refolding reactions of iron(III) cytochrome c Type Journal Article
Year 1981 Publication Biochemistry Abbreviated Journal Biochemistry
Volume 20 Issue (down) 6 Pages 1622-1630
Keywords Animals; Ascorbic Acid; *Cytochrome c Group; Guanidines; Horses; Kinetics; Oxidation-Reduction; Protein Conformation; Spectrum Analysis
Abstract The fast and slow refolding reactions of iron(III) cytochrome c (Fe(III) cyt c), previously studied by Ikai et al. (Ikai, A., Fish, W. W., & Tanford, C. (1973) J. Mol. Biol. 73, 165--184), have been reinvestigated. The fast reaction has the major amplitude (78%) and is 100-fold faster than the slow reaction in these conditions (pH 7.2, 25 degrees C, 1.75 M guanidine hydrochloride). We show here that native cyt c is the product formed in the fast reaction as well as in the slow reaction. Two probes have been used to test for formation of native cyt c. absorbance in the 695-nm band and rate of reduction of by L-ascorbate. Different unfolded species (UF, US) give rise to the fast and slow refolding reactions, as shown both by refolding assays at different times after unfolding (“double-jump” experiments) and by the formation of native cyt c in each of the fast and slow refolding reactions. Thus the fast refolding reaction is UF leads to N and the slow refolding reaction is Us leads to N, where N is native cyt c, and there is a US in equilibrium UF equilibrium in unfolded cyt c. The results are consistent with the UF in equilibrium US reaction being proline isomerization, but this has not yet been tested in detail. Folding intermediates have been detected in both reactions. In the UF leads to N reaction, the Soret absorbance change precedes the recovery of the native 695-nm band spectrum, showing that Soret absorbance monitors the formation of a folding intermediate. In the US leads to N reaction an ascorbate-reducible intermediate has been found at an early stage in folding and the Soret absorbance change occurs together with the change at 695 nm as N is formed in the final stage of folding.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0006-2960 ISBN Medium
Area Expedition Conference
Notes PMID:6261802 Approved no
Call Number Equine Behaviour @ team @ Serial 3809
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Author Czerlinski, G.H.; Erickson, J.O.; Theorell, H.
Title Chemical relaxation studies on the horse liver alcohol dehydrogenase system Type Journal Article
Year 1979 Publication Physiological Chemistry and Physics Abbreviated Journal Physiol Chem Phys
Volume 11 Issue (down) 6 Pages 537-569
Keywords Alcohol Oxidoreductases/*metabolism; Animals; Buffers; Electron Transport; Ethanol/metabolism; Horses; Hydrogen-Ion Concentration; Liver/*enzymology; Mathematics; NAD/metabolism; Oscillometry; Osmolar Concentration; Temperature; Time Factors
Abstract Chemical relaxation studies on the system horse liver alcohol dehydrogenase, nicotinamide adenine dinucleotide, and ethanol were conducted observing fluorescence changes between 400 and 500 nm. Temperature-jump experiments were performed at pH 6.5, 7.0, 8.0, and 9.0; concentration-jump experiments at pH 9.0. The reciprocal of the slowest relaxation time was found to be linearly dependent upon the enzyme concentration for relatively low enzyme concentrations, as predicted earlier. Use of the wide pH-range necessitated expression of the four apparent dissociation constants of the catalytic reaction cycle in terms of pH-independent constants. The system was described in terms of only one (or two) catalysis-linked protons not associated with the electron transfer. Protonic steps in a buffered system are in rapid equilibrium, too fast to be measured with the equipment available. Assuming only two of the four bimolecular reaction steps in the four-step cycle are fast compared to the remaining two, six cases may be considered with six expressions for the reciprocal of the slowest relaxation time. Comparison with the experimental data revealed that the bimolecular reaction steps governing the slowest relaxation time change with pH. Above the effective time resolution of the temperature-lump instrument with fluorescence detection (0.1 msec) only one other relaxation time was detectable and only at pH 9. This relaxation time, found to be independent of the concentration of all reactants within experimental error (r = 10 +/- 5 msec), is most likely due to an interconversion among ternary complexes.
Address
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0031-9325 ISBN Medium
Area Expedition Conference
Notes PMID:44918 Approved no
Call Number Equine Behaviour @ team @ Serial 3813
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Author Emery, N.J.
Title The eyes have it: the neuroethology, function and evolution of social gaze Type Journal Article
Year 2000 Publication Neuroscience and Biobehavioral Reviews Abbreviated Journal Neurosci Biobehav Rev
Volume 24 Issue (down) 6 Pages 581-604
Keywords Animals; *Eye; Fixation, Ocular; Humans; *Social Behavior
Abstract Gaze is an important component of social interaction. The function, evolution and neurobiology of gaze processing are therefore of interest to a number of researchers. This review discusses the evolutionary role of social gaze in vertebrates (focusing on primates), and a hypothesis that this role has changed substantially for primates compared to other animals. This change may have been driven by morphological changes to the face and eyes of primates, limitations in the facial anatomy of other vertebrates, changes in the ecology of the environment in which primates live, and a necessity to communicate information about the environment, emotional and mental states. The eyes represent different levels of signal value depending on the status, disposition and emotional state of the sender and receiver of such signals. There are regions in the monkey and human brain which contain neurons that respond selectively to faces, bodies and eye gaze. The ability to follow another individual's gaze direction is affected in individuals with autism and other psychopathological disorders, and after particular localized brain lesions. The hypothesis that gaze following is “hard-wired” in the brain, and may be localized within a circuit linking the superior temporal sulcus, amygdala and orbitofrontal cortex is discussed.
Address Center for Neuroscience, Department of Psychiatry & California Regional Primate Research Center, University of California, Davis, CA 95616, USA. njemery@ucdavis.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0149-7634 ISBN Medium
Area Expedition Conference
Notes PMID:10940436 Approved no
Call Number refbase @ user @ Serial 3996
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Author Verheyen, K.; Price, J.; Lanyon, L.; Wood, J.
Title Exercise distance and speed affect the risk of fracture in racehorses Type Journal Article
Year 2006 Publication Bone Abbreviated Journal Bone
Volume 39 Issue (down) 6 Pages 1322-1330
Keywords Animals; Case-Control Studies; Cohort Studies; England; Exertion; Female; Fractures, Bone/etiology/*veterinary; Horse Diseases/*etiology; Horses/*injuries; Male; Physical Conditioning, Animal/adverse effects/methods; Poisson Distribution; Prospective Studies; Regression Analysis; Risk Factors; Running/injuries/physiology
Abstract In order to gain insight into those training regimens that can minimise the risk of fracture in athletic populations, we conducted a large epidemiological study in racehorses. Thoroughbred racehorses provide a suitable model for studying fracture development and exercise-related risk factors in physically active populations. They represent a homogeneous population, undertaking intensive exercise programmes that are sufficiently heterogeneous to determine those factors that influence injury risk. Daily exercise information was recorded for a cohort of 1178 thoroughbreds that were monitored for up to 2 years. A total of 148 exercise-induced fractures occurred in the study population. Results from a nested case-control study showed a strong interactive effect of exercise distances at different speeds on fracture risk. Horses that exceeded 44 km at canter (< or =14 m/s) and 6 km at gallop (>14 m/s) in a 30-day period were at particularly increased risk of fracture. These distances equate to ca. 7700 bone loading cycles at canter and 880 loading cycles at gallop. Fifty-six fractures occurred in the subset of study horses that were followed since entering training as yearlings, when skeletally immature (n = 335). Cohort analysis of this data set showed that, in previously untrained bones, accumulation of canter exercise increased the risk of fracture (P < or = 0.01), whereas accumulation of high-speed gallop exercise had a protective effect (P < 0.01). However, increasing distances at canter and gallop in short time periods (up to one month) were associated with an increasing fracture risk. All training exercise involves a balance between the risk of fracture inherent in exposure to loading and the beneficial effect that loading has by stimulating bone cells to produce a more robust architecture. Results from our study provide important epidemiological evidence of the effects of physical exercise on bone adaptation and injury risk and can be used to inform the design of safer exercise regimens in physically active populations.
Address Epidemiology Unit, Animal Health Trust, Newmarket, United Kingdom. kverheyen@rvc.ac.uk
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 8756-3282 ISBN Medium
Area Expedition Conference
Notes PMID:16926125 Approved no
Call Number Equine Behaviour @ team @ Serial 4030
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Author Lagarde, J.; Kelso, J.A.S.; Peham, C.; Licka, T.
Title Coordination dynamics of the horse-rider system Type Journal Article
Year 2005 Publication Journal of Motor Behavior Abbreviated Journal J Mot Behav
Volume 37 Issue (down) 6 Pages 418-424
Keywords Animals; Biomechanics; *Horses; Humans; Professional Competence; Psychomotor Performance/*physiology; *Sports; Time Factors
Abstract The authors studied the interaction between rider and horse by measuring their ensemble motions in a trot sequence, comparing 1 expert and 1 novice rider. Whereas the novice's movements displayed transient departures from phase synchrony, the expert's motions were continuously phase-matched with those of the horse. The tight ensemble synchrony between the expert and the horse was accompanied by an increase in the temporal regularity of the oscillations of the trunk of the horse. Observed differences between expert and novice riders indicated that phase synchronization is by no means perfect but requires extended practice. Points of contact between horse and rider may haptically convey effective communication between them.
Address Center for Complex Systems and Brain Sciences, Florida Atlantic University, Boca Raton, FL 33431-771, USA. lagarde@ccs.fau.edu
Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0022-2895 ISBN Medium
Area Expedition Conference
Notes PMID:16280312 Approved no
Call Number Equine Behaviour @ team @ Serial 4034
Permanent link to this record