| Records |
Author  |
Hillidge, C.J.; Lees, P. |
| Title |
Cardiac output in the conscious and anaesthetised horse |
Type |
Journal Article |
| Year |
1975 |
Publication |
Equine veterinary journal |
Abbreviated Journal |
Equine Vet J |
| Volume |
7 |
Issue |
1 |
Pages |
16-21 |
| Keywords |
Anesthesia, Inhalation/*veterinary; Animals; Carbon Dioxide/blood; *Cardiac Output/veterinary; *Consciousness; Electrocardiography/veterinary; Ether, Ethyl; Female; Halothane; Heart Rate; Heart Ventricles/physiology; Horses/*physiology; Hydrogen-Ion Concentration; Male; Oxygen/blood; Posture |
| Abstract |
Cardiac output in the horse was measured before and at predetermined times during 2-hour periods of thiopentone-halothane and thiopentone-diethyl ether anaesthesia. Left ventricular stroke volume was decreased to a similar extent during anaesthesia with each volatile agent, but a greater reduction in cardiac output occurred during halothane anaesthesia. This finding reflected the differing effects of halothane and ether on heart rate, a slight bradycardia occurring with the former agent while ether produced a small degree of tachycardia. The latter effect was attributed to enhanced sympathoadrenal activity. Changes in cardiac output and stroke volume were considered in relation to other factors, including arterial blood pH and tensions of oxygen and carbon dioxide. Positive correlations between some of these variables and cardiac function were established. With both volatile agents the reductions in stroke volume and cardiac output were related to the duration of anaesthesia, being greatest during the early stages. Possible reasons for the tendency of stroke volume and cardiac output to return towards control levels are discussed. |
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English |
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| ISSN |
0425-1644 |
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| Notes |
PMID:234842 |
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no |
| Call Number |
refbase @ user @ |
Serial |
102 |
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| Author |
Lees, P.; Tavernor, W.D. |
| Title |
Influence of halothane and catecholamines on heart rate and rhythm in the horse |
Type |
Journal Article |
| Year |
1970 |
Publication |
British journal of pharmacology |
Abbreviated Journal |
Br J Pharmacol |
| Volume |
39 |
Issue |
1 |
Pages |
149-159 |
| Keywords |
Anesthesia, Inhalation; Animals; Arrhythmia/*chemically induced; Atropine/pharmacology; Catecholamines/*pharmacology; Consciousness; Epinephrine/administration & dosage; Ethers; Female; Halothane/*pharmacology; Heart Rate/*drug effects; Horses; Hypercapnia/physiopathology; Isoproterenol/pharmacology; Male; Norepinephrine/pharmacology; Propranolol/pharmacology |
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English |
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| ISSN |
0007-1188 |
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| Notes |
PMID:5420092 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
103 |
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| Author |
Tavernor, W.D.; Lees, P. |
| Title |
A pharmacological investigation of the influence of suxamethonium on cardiac function in the horse |
Type |
Journal Article |
| Year |
1968 |
Publication |
Experientia |
Abbreviated Journal |
Experientia |
| Volume |
24 |
Issue |
6 |
Pages |
582-583 |
| Keywords |
Animals; Arrhythmia/chemically induced; Consciousness; Halothane; Heart/innervation; Heart Rate/*drug effects; Horses/*physiology; Oxygen; Propranolol/pharmacology; Receptors, Sensory/drug effects; Stimulation, Chemical; Succinylcholine/antagonists & inhibitors/*pharmacology; Sympathetic Nervous System/physiology; Tachycardia/chemically induced; Thiopental |
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0014-4754 |
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| Notes |
PMID:5697737 |
Approved |
no |
| Call Number |
refbase @ user @ |
Serial |
104 |
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