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Author Alexander, F.
Title Effect of phenylbutazone on electrolyte metabolism in ponies Type Journal Article
Year 1982 Publication The Veterinary record Abbreviated Journal Vet. Rec.
Volume 110 Issue 12 Pages 271-272
Keywords Animals; Chlorides/metabolism; Electrolytes/*metabolism; Horses/*metabolism; Male; Phenylbutazone/*pharmacology; Sodium/metabolism
Abstract Phenylbutazone administered in therapeutic doses to ponies decreased urinary sodium and chloride excretion. The volume and osmolality of the urine was unaffected as was potassium excretion. Faecal excretion of chloride decreased and that of potassium increased, while faecal sodium excretion was unaffected. Plasma pH, bicarbonate and total carbon dioxide decreased after phenylbutazone administration. Packed cell volume, plasma sodium, potassium, carbon dioxide tension and chloride were unchanged.
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
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ISSN 0042-4900 ISBN Medium
Area Expedition Conference
Notes PMID:7080416 Approved no
Call Number refbase @ user @ Serial (up) 109
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Author Alexander, F.
Title The effect of some anti-diarrhoeal drugs on intestinal transit and faecal excretion of water and electrolytes in the horse Type Journal Article
Year 1978 Publication Equine veterinary journal Abbreviated Journal Equine Vet J
Volume 10 Issue 4 Pages 229-234
Keywords Animals; Antidiarrheals/*pharmacology; Atropine/pharmacology; Electrolytes/*analysis/urine; Feces/*analysis; Gastrointestinal Motility/*drug effects; Horses/*metabolism/physiology; Loperamide/pharmacology; Male; Meperidine/pharmacology; Morphine/pharmacology; Opium/pharmacology; Water/*analysis
Abstract The effect of morphine, Tinct. opii, loperamide, pethidine and atropine on intestinal transit and the faecal and urinary excretion of water and electrolytes was studied in ponies. The rate of passage of a particulate marker was slowed by morphine, hastened then slowed by loperamide and Tinct. opii, and hastened by atropine. The liquid marker was slowed by Tinct. opii and hastened then slowed by the other drugs. Only loperamide decreased the faecal sodium excretion. This drug also decreased faecal water and weight; it appeared worthy of clinical trial in diarrhoea. Tinct. opii decreased by morphine, pethidine and atropine increased faecal water.
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ISSN 0425-1644 ISBN Medium
Area Expedition Conference
Notes PMID:738263 Approved no
Call Number refbase @ user @ Serial (up) 110
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Author Alexander, F.
Title The effect of diuretics on the faecal excretion of water and electrolytes in horses Type Journal Article
Year 1977 Publication British journal of pharmacology Abbreviated Journal Br J Pharmacol
Volume 60 Issue 4 Pages 589-593
Keywords Animals; Body Water/*metabolism; Chlorides/metabolism; Electrolytes/*metabolism; Feces/*analysis; Furosemide/*pharmacology; Horses; Hydrochlorothiazide/*pharmacology; Male; Potassium/metabolism; Sodium/metabolism; Time Factors
Abstract 1. The effect on plasma, urinary and faecal electrolytes of frusemide and hydrochlorthiazide was measured in ponies, mean weight 180 kg. 2. The rapid loss in urine of large quantities of sodium had only a small effect on plasma sodium concentration. 3. Faecal sodium excretion was increased substantially after the administration of frusemide. 4. Frusemide increased faecal potassium during the 48 h following administration and faecal water in the 24/48 h period. It also produced a hypopotassaemia. 5. Hydrochlorthiazide increased faecal chloride during the 24 h after administration. 6. Frusemide increased the intestinal transit time of both liquid (polyethylene glycol) and particulate (Cr2O3) markers.
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-1188 ISBN Medium
Area Expedition Conference
Notes PMID:907872 Approved no
Call Number refbase @ user @ Serial (up) 111
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Author Alexander, F.; Collett, R.A.
Title Proceedings: Some observations on the pharmacokinetics of trimethoprim in the horse Type Journal Article
Year 1974 Publication British journal of pharmacology Abbreviated Journal Br J Pharmacol
Volume 52 Issue 1 Pages 142p
Keywords Animals; Half-Life; Horses/*metabolism; Kinetics; Trimethoprim/*metabolism
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-1188 ISBN Medium
Area Expedition Conference
Notes PMID:4451793 Approved no
Call Number refbase @ user @ Serial (up) 112
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Author Alexander, F.; Collett, R.A.
Title Pethidine in the horse Type Journal Article
Year 1974 Publication Research in veterinary science Abbreviated Journal Res Vet Sci
Volume 17 Issue 1 Pages 136-137
Keywords Animals; Half-Life; Horses/*metabolism; Injections, Intravenous/veterinary; Male; Meperidine/administration & dosage/analysis/*metabolism/pharmacology
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0034-5288 ISBN Medium
Area Expedition Conference
Notes PMID:4421117 Approved no
Call Number refbase @ user @ Serial (up) 113
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Author Alexander, F.; Davies, M.E.; Muir, A.R.
Title Bacteriophage-like particles in the large intestine of the horse Type Journal Article
Year 1970 Publication Research in veterinary science Abbreviated Journal Res Vet Sci
Volume 11 Issue 6 Pages 592-593
Keywords Animals; Bacteriophages/*isolation & purification; Cecum/microbiology; Colon/microbiology
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Language English Summary Language Original Title
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ISSN 0034-5288 ISBN Medium
Area Expedition Conference
Notes PMID:5498578 Approved no
Call Number refbase @ user @ Serial (up) 114
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Author Alexander, F.
Title Multiple fistulation of the horse's large intestine Type Journal Article
Year 1970 Publication The British veterinary journal Abbreviated Journal Br. Vet. J.
Volume 126 Issue 11 Pages 604-606
Keywords Animals; Cecum/physiology; Colon/physiology; Horses/*physiology; Intestinal Fistula; Intestine, Large/*physiology; *Intubation, Gastrointestinal; Methods
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Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-1935 ISBN Medium
Area Expedition Conference
Notes PMID:5492494 Approved no
Call Number refbase @ user @ Serial (up) 115
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Author Alexander, F.; Davies, M.E.
Title Studies on vitamin B12 in the horse Type Journal Article
Year 1969 Publication The British veterinary journal Abbreviated Journal Br. Vet. J.
Volume 125 Issue 4 Pages 169-176
Keywords Animals; Biological Assay; Cattle; Chickens; Feces/analysis; Horses/*metabolism; Humans; Lactobacillus/metabolism; Rabbits; Rats; Sheep; Urine/analysis; Vitamin B 12/*analysis
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0007-1935 ISBN Medium
Area Expedition Conference
Notes PMID:5814055 Approved no
Call Number refbase @ user @ Serial (up) 116
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Author Alexander, F.; Nicholson, J.D.
Title The blood and saliva clearances of phenobarbitone and pentobarbitone in the horse Type Journal Article
Year 1968 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol
Volume 17 Issue 2 Pages 203-210
Keywords Animals; Female; *Horses; Injections, Intravenous; Male; Metabolic Clearance Rate; Pentobarbital/blood/*metabolism; Phenobarbital/blood/*metabolism; Protein Binding; *Saliva; Time Factors
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Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0006-2952 ISBN Medium
Area Expedition Conference
Notes PMID:5647047 Approved no
Call Number refbase @ user @ Serial (up) 117
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Author Alexander, F.; Horner, M.W.; Moss, M.S.
Title The salivary secretion and clearance in the horse of chloral hydrate and its metabolites Type Journal Article
Year 1967 Publication Biochemical pharmacology Abbreviated Journal Biochem Pharmacol
Volume 16 Issue 7 Pages 1305-1311
Keywords Animals; Chloral Hydrate/blood/*metabolism/urine; Chromatography, Gas; Ethanol/blood/urine; Horses; Male; Parotid Gland/metabolism; Saliva/*analysis; Trichloroacetic Acid/blood/urine
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Corporate Author Thesis
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0006-2952 ISBN Medium
Area Expedition Conference
Notes PMID:6053598 Approved no
Call Number refbase @ user @ Serial (up) 118
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